DE69509279T2 - Wässrige konzentrierte Lösungen enthaltend Argatroban - Google Patents

Wässrige konzentrierte Lösungen enthaltend Argatroban

Info

Publication number
DE69509279T2
DE69509279T2 DE69509279T DE69509279T DE69509279T2 DE 69509279 T2 DE69509279 T2 DE 69509279T2 DE 69509279 T DE69509279 T DE 69509279T DE 69509279 T DE69509279 T DE 69509279T DE 69509279 T2 DE69509279 T2 DE 69509279T2
Authority
DE
Germany
Prior art keywords
solutions containing
concentrated solutions
aqueous concentrated
argatroban
esp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69509279T
Other languages
English (en)
Other versions
DE69509279D1 (de
Inventor
Frederic Andre
Veronique Avril
Jean Montel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of DE69509279D1 publication Critical patent/DE69509279D1/de
Publication of DE69509279T2 publication Critical patent/DE69509279T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
DE69509279T 1994-02-03 1995-02-02 Wässrige konzentrierte Lösungen enthaltend Argatroban Expired - Fee Related DE69509279T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401195A FR2715566B1 (fr) 1994-02-03 1994-02-03 Solutions aqueuses concentrées d'argatroban.

Publications (2)

Publication Number Publication Date
DE69509279D1 DE69509279D1 (de) 1999-06-02
DE69509279T2 true DE69509279T2 (de) 1999-11-25

Family

ID=9459714

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69509279T Expired - Fee Related DE69509279T2 (de) 1994-02-03 1995-02-02 Wässrige konzentrierte Lösungen enthaltend Argatroban

Country Status (25)

Country Link
US (1) US5679690A (de)
EP (1) EP0669131B1 (de)
JP (1) JP3027103B2 (de)
KR (1) KR100257692B1 (de)
CN (1) CN1054743C (de)
AT (1) ATE179327T1 (de)
AU (1) AU687133B2 (de)
CA (1) CA2141704C (de)
CZ (1) CZ284611B6 (de)
DE (1) DE69509279T2 (de)
DK (1) DK0669131T3 (de)
ES (1) ES2132547T3 (de)
FI (1) FI950459A (de)
FR (1) FR2715566B1 (de)
GR (1) GR3030149T3 (de)
HK (1) HK1013623A1 (de)
HU (1) HU218220B (de)
IL (1) IL112527A (de)
NO (1) NO307324B1 (de)
NZ (1) NZ270445A (de)
PL (1) PL178586B1 (de)
RU (1) RU2136282C1 (de)
SK (1) SK12795A3 (de)
TW (1) TW436295B (de)
ZA (1) ZA95837B (de)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840733A (en) * 1996-07-01 1998-11-24 Redcell, Canada, Inc. Methods and compositions for producing novel conjugates of thrombin inhibitors and endogenous carriers resulting in anti-thrombins with extended lifetimes
US5786153A (en) * 1996-09-12 1998-07-28 Chiron Diagnostics Corporation Prevention of probe coating on automated analyzers using a non-denaturing surfactant
WO1998053828A1 (fr) * 1997-05-27 1998-12-03 Senju Pharmaceutical Co., Ltd. Preparations aqueuses contenant de l'israpafant
US9066695B2 (en) 1998-04-30 2015-06-30 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8688188B2 (en) 1998-04-30 2014-04-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8346337B2 (en) 1998-04-30 2013-01-01 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US6949816B2 (en) 2003-04-21 2005-09-27 Motorola, Inc. Semiconductor component having first surface area for electrically coupling to a semiconductor chip and second surface area for electrically coupling to a substrate, and method of manufacturing same
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US8974386B2 (en) 1998-04-30 2015-03-10 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8480580B2 (en) 1998-04-30 2013-07-09 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
US8465425B2 (en) 1998-04-30 2013-06-18 Abbott Diabetes Care Inc. Analyte monitoring device and methods of use
FR2793412B1 (fr) * 1999-05-11 2001-07-27 Synthelabo Formulations galeniques d'argatroban pour administration sous-cutanee
KR100399373B1 (ko) * 2000-12-20 2003-09-26 주식회사 아이센스 콜란산 고리를 포함하는 디글라이콜릭 디아마이드 유도체,그의 제조방법 및 용도
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
EP1397068A2 (de) 2001-04-02 2004-03-17 Therasense, Inc. Gerät und verfahren zur blutzuckerverfolgung
US6984395B2 (en) * 2001-04-11 2006-01-10 Qlt, Inc. Drug delivery system for hydrophobic drugs
AU2003303597A1 (en) 2002-12-31 2004-07-29 Therasense, Inc. Continuous glucose monitoring system and methods of use
KR101010547B1 (ko) * 2003-03-20 2011-01-24 미쓰비시 타나베 파마 코퍼레이션 알기닌아미드류를 함유하는 의약 제제
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
EP1718198A4 (de) 2004-02-17 2008-06-04 Therasense Inc Verfahren und system zur bereitstellung einer datenkommunikation in einem kontinuierlichen blutzuckerüberwachungs- und managementsystem
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
KR20080042155A (ko) * 2005-09-01 2008-05-14 백스터 인터내셔널 인코포레이티드 가용화제로서의 산을 포함하는 아가트로반 제제
US7766829B2 (en) 2005-11-04 2010-08-03 Abbott Diabetes Care Inc. Method and system for providing basal profile modification in analyte monitoring and management systems
US7620438B2 (en) 2006-03-31 2009-11-17 Abbott Diabetes Care Inc. Method and system for powering an electronic device
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US7920907B2 (en) 2006-06-07 2011-04-05 Abbott Diabetes Care Inc. Analyte monitoring system and method
CA2662853C (en) * 2006-08-31 2016-07-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US7687516B2 (en) * 2006-09-27 2010-03-30 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
JP5624766B2 (ja) * 2006-09-27 2014-11-12 イーグル・ファーマシューティカルズ・インコーポレーテッド アルコールを含まないアルガトロバン製剤
US20100076019A1 (en) * 2006-10-11 2010-03-25 Eagle Pharmaceuticals, Inc. Alcohol free formulation of argatroban
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
WO2008135828A2 (en) 2007-05-03 2008-11-13 Pfizer Products Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US8703204B2 (en) 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
WO2008149192A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
EP2240162A4 (de) 2007-12-06 2013-10-09 Bend Res Inc Nanoteilchen mit einem nicht-ionisierbaren polymer und einem amin-funktionalisierten methacrylat-copolymer
EP2231169B1 (de) 2007-12-06 2016-05-04 Bend Research, Inc. Pharmazeutische zusammensetzungen mit nanopartikeln und resuspensionsmaterial
US7915290B2 (en) * 2008-02-29 2011-03-29 Baxter International Inc. Argatroban formulations and methods for making and using same
US20090221637A1 (en) * 2008-02-29 2009-09-03 Baxter International Inc. Solid-state salt argatroban formulations and methods for producing and using the same
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US9226701B2 (en) 2009-04-28 2016-01-05 Abbott Diabetes Care Inc. Error detection in critical repeating data in a wireless sensor system
WO2010138856A1 (en) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Medical device antenna systems having external antenna configurations
WO2011026148A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte monitoring system and methods for managing power and noise
WO2011026147A1 (en) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Analyte signal processing device and methods
US9320461B2 (en) 2009-09-29 2016-04-26 Abbott Diabetes Care Inc. Method and apparatus for providing notification function in analyte monitoring systems
CN102366410B (zh) * 2011-09-14 2013-05-29 海南灵康制药有限公司 一种阿加曲班脂质体注射剂
JP6443802B2 (ja) 2011-11-07 2018-12-26 アボット ダイアベティス ケア インコーポレイテッドＡｂｂｏｔｔ Ｄｉａｂｅｔｅｓ Ｃａｒｅ Ｉｎｃ． 分析物モニタリング装置および方法
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
US20150034098A1 (en) 2013-07-11 2015-02-05 Aqua Turf International, Inc. Air filtration mask with opening front cover
DE102014108210A1 (de) 2014-06-11 2015-12-17 Dietrich Gulba Rodentizid
CN114025746B (zh) * 2019-05-10 2023-08-25 福多兹制药公司 抗血栓形成剂的可注射聚合物纳米颗粒组合物及其方法
CN110478471B (zh) * 2019-09-17 2020-04-10 鲁南制药集团股份有限公司 一种阿加曲班注射液及其制备方法
KR20220145892A (ko) 2020-07-03 2022-10-31 도시바 미쓰비시덴키 산교시스템 가부시키가이샤 무정전 전원 시스템
EP4070658A1 (de) 2021-04-06 2022-10-12 BIORoxx GmbH Verwendung von blutgerinnungshemmenden verbindungen als rodentizide
CN113855635A (zh) * 2021-10-20 2021-12-31 陇南市第一人民医院 一种阿加曲班注射液脂质体及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE48623B1 (en) * 1978-08-31 1985-03-20 Mitsubishi Chem Ind Alpha-(n-arylsulfonyl-l-argininamides,processes for their preparation and pharmaceutical compositions containing these substances
JPS6431727A (en) * 1987-07-28 1989-02-02 Mitsubishi Chem Ind Dissolution of argininamide and drug composition containing argininamides
JPH02129123A (ja) * 1988-11-07 1990-05-17 Mitsubishi Kasei Corp 抗血液凝固剤
CA2091715A1 (en) * 1992-03-18 1993-09-19 Mitsubishi Kasei Corporation Argatroban preparations for ophthalmic use
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use

Also Published As

Publication number Publication date
FI950459A (fi) 1995-08-04
CA2141704C (fr) 2001-07-03
HK1013623A1 (en) 1999-09-03
SK12795A3 (en) 1995-08-09
HUT71524A (en) 1995-12-28
ZA95837B (en) 1996-03-29
IL112527A (en) 1999-04-11
NO950377D0 (no) 1995-02-02
TW436295B (en) 2001-05-28
CZ284611B6 (cs) 1999-01-13
CZ27195A3 (en) 1995-09-13
NO950377L (no) 1995-08-04
KR100257692B1 (ko) 2000-08-01
AU687133B2 (en) 1998-02-19
RU95101387A (ru) 1997-02-27
ES2132547T3 (es) 1999-08-16
CA2141704A1 (fr) 1995-08-04
CN1109754A (zh) 1995-10-11
FR2715566B1 (fr) 1996-03-08
FI950459A0 (fi) 1995-02-02
IL112527A0 (en) 1995-05-26
PL307041A1 (en) 1995-08-07
DK0669131T3 (da) 1999-11-01
RU2136282C1 (ru) 1999-09-10
AU1154395A (en) 1995-08-10
NZ270445A (en) 1995-07-26
US5679690A (en) 1997-10-21
EP0669131A1 (de) 1995-08-30
GR3030149T3 (en) 1999-08-31
PL178586B1 (pl) 2000-05-31
EP0669131B1 (de) 1999-04-28
CN1054743C (zh) 2000-07-26
HU218220B (hu) 2000-06-28
JP3027103B2 (ja) 2000-03-27
DE69509279D1 (de) 1999-06-02
ATE179327T1 (de) 1999-05-15
NO307324B1 (no) 2000-03-20
JPH07277980A (ja) 1995-10-24
KR950031042A (ko) 1995-12-18
FR2715566A1 (fr) 1995-08-04

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-SYNTHELABO, PARIS, FR

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee