DE69503885T2 - Gemeinschaftlich verwendete genetische marker zur diagnostik der alzheimerschen krankheit, methode und diagnostischer reagenziensatz - Google Patents

Gemeinschaftlich verwendete genetische marker zur diagnostik der alzheimerschen krankheit, methode und diagnostischer reagenziensatz

Info

Publication number
DE69503885T2
DE69503885T2 DE69503885T DE69503885T DE69503885T2 DE 69503885 T2 DE69503885 T2 DE 69503885T2 DE 69503885 T DE69503885 T DE 69503885T DE 69503885 T DE69503885 T DE 69503885T DE 69503885 T2 DE69503885 T2 DE 69503885T2
Authority
DE
Germany
Prior art keywords
alzheimer
disease
genetic markers
pct
diagnostics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69503885T
Other languages
English (en)
Other versions
DE69503885D1 (de
Inventor
Philippe Amouyel
Marie-Christin Chartier-Harlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Original Assignee
Institut Pasteur de Lille
Institut National de la Sante et de la Recherche Medicale INSERM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institut Pasteur de Lille, Institut National de la Sante et de la Recherche Medicale INSERM filed Critical Institut Pasteur de Lille
Publication of DE69503885D1 publication Critical patent/DE69503885D1/de
Application granted granted Critical
Publication of DE69503885T2 publication Critical patent/DE69503885T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
DE69503885T 1994-03-07 1995-03-06 Gemeinschaftlich verwendete genetische marker zur diagnostik der alzheimerschen krankheit, methode und diagnostischer reagenziensatz Expired - Lifetime DE69503885T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9402603A FR2716894B1 (fr) 1994-03-07 1994-03-07 Marqueurs génétiques utilisés conjointement pour le diagnostic de la maladie d'Alzheimer, méthode et kit de diagnostic.
PCT/FR1995/000259 WO1995024504A1 (fr) 1994-03-07 1995-03-06 Marqueurs genetiques utilises conjointement pour le diagnostic de la maladie d'alzheimer, methode et kit de diagnostic

Publications (2)

Publication Number Publication Date
DE69503885D1 DE69503885D1 (de) 1998-09-10
DE69503885T2 true DE69503885T2 (de) 1999-04-22

Family

ID=9460754

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69503885T Expired - Lifetime DE69503885T2 (de) 1994-03-07 1995-03-06 Gemeinschaftlich verwendete genetische marker zur diagnostik der alzheimerschen krankheit, methode und diagnostischer reagenziensatz

Country Status (9)

Country Link
US (1) US5942392A (de)
EP (1) EP0749498B1 (de)
JP (1) JP3662585B2 (de)
AT (1) ATE169343T1 (de)
CA (1) CA2184635C (de)
DE (1) DE69503885T2 (de)
DK (1) DK0749498T3 (de)
FR (1) FR2716894B1 (de)
WO (1) WO1995024504A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022683A (en) * 1996-12-16 2000-02-08 Nova Molecular Inc. Methods for assessing the prognosis of a patient with a neurodegenerative disease
ES2128265B1 (es) * 1997-06-04 2000-03-01 Euroespes S A Kit genetico para la caracterizacion molecular de la enfermedad de alzheimer.
FR2765591B1 (fr) * 1997-07-01 2002-08-09 Pasteur Institut Procede de diagnostic de la maladie d'alzheimer
CA2297005A1 (en) * 1997-09-12 1999-03-25 Anthony David Smith Method for determining propensity for developing late-onset alzheimer's disease
US6251587B1 (en) 1997-12-16 2001-06-26 Nova Molecular, Inc. Method for determining the prognosis of a patient with a neurological disease
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
EP1001037A3 (de) * 1998-09-28 2003-10-01 Whitehead Institute For Biomedical Research Vorselektion und Isolierung eines Einzelnukleotidpolymorphismus
DE69903278D1 (de) * 1999-07-09 2002-11-07 Inst Pasteur De Lille Lille Verfahren zur Diagnose oder zur Prognose von Alzheimer Krankheit: therapeutische Zusammensetzung zur Verhinderung oder zur Behandlung von Alzheimer Krankheit
WO2004011943A1 (en) * 2002-07-30 2004-02-05 The Regents Of The University Of California Method of diagnosing alzheimer's disease
EP1623996A1 (de) * 2004-08-06 2006-02-08 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Verbessertes Verfahren zur Auswahl eines Proteins von einer Bibliothek
US8071307B2 (en) 2005-04-04 2011-12-06 Asubio Pharma Co., Ltd. Method of detecting relative risk for the onset of atopic dermatitis by gene single nucleotide polymorphism analysis
WO2006110621A2 (en) * 2005-04-11 2006-10-19 Cornell Research Foundation, Inc. Multiplexed biomarkers for monitoring the alzheimer's disease state of a subject
JP2008538496A (ja) 2005-04-12 2008-10-30 ４５４ ライフ サイエンシーズ コーポレイション ウルトラディープ配列決定を用いて配列変異体を決定するための方法
US20060228721A1 (en) 2005-04-12 2006-10-12 Leamon John H Methods for determining sequence variants using ultra-deep sequencing
CA2679511A1 (en) * 2007-03-16 2008-09-25 454 Life Sciences Corporation System and method for detection of hiv drug resistant variants

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ257215A (en) * 1992-10-13 1996-12-20 Univ Duke Diagnosis or prognosis of alzheimers using the presence of apolipoprotein e type 4 as an indicator and apolipoprotein e isoform specific antibodies

Also Published As

Publication number Publication date
FR2716894B1 (fr) 1996-05-24
CA2184635A1 (fr) 1995-09-14
EP0749498B1 (de) 1998-08-05
FR2716894A1 (fr) 1995-09-08
DE69503885D1 (de) 1998-09-10
US5942392A (en) 1999-08-24
DK0749498T3 (da) 1999-05-10
CA2184635C (fr) 2008-11-18
EP0749498A1 (de) 1996-12-27
JPH09511138A (ja) 1997-11-11
ATE169343T1 (de) 1998-08-15
WO1995024504A1 (fr) 1995-09-14
JP3662585B2 (ja) 2005-06-22

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