DE69434314D1 - Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse - Google Patents

Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse

Info

Publication number
DE69434314D1
DE69434314D1 DE69434314T DE69434314T DE69434314D1 DE 69434314 D1 DE69434314 D1 DE 69434314D1 DE 69434314 T DE69434314 T DE 69434314T DE 69434314 T DE69434314 T DE 69434314T DE 69434314 D1 DE69434314 D1 DE 69434314D1
Authority
DE
Germany
Prior art keywords
genanalysis
mononucleotides
polymorphism
sites
ancestry
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69434314T
Other languages
English (en)
Other versions
DE69434314T2 (de
Inventor
Philip Goelet
R Knapp
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Orchid Cellmark Inc
Original Assignee
Orchid Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26842710&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69434314(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Orchid Biosciences Inc filed Critical Orchid Biosciences Inc
Application granted granted Critical
Publication of DE69434314D1 publication Critical patent/DE69434314D1/de
Publication of DE69434314T2 publication Critical patent/DE69434314T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
DE69434314T 1993-11-03 1994-11-02 Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse Revoked DE69434314T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14514593A 1993-11-03 1993-11-03
US145145 1993-11-03
US21653894A 1994-03-23 1994-03-23
US216538 1994-03-23
PCT/US1994/012632 WO1995012607A1 (en) 1993-11-03 1994-11-02 Single nucleotide polymorphisms and their use in genetic analysis

Publications (2)

Publication Number Publication Date
DE69434314D1 true DE69434314D1 (de) 2005-04-28
DE69434314T2 DE69434314T2 (de) 2006-03-30

Family

ID=26842710

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434314T Revoked DE69434314T2 (de) 1993-11-03 1994-11-02 Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse

Country Status (8)

Country Link
US (2) US20020094525A1 (de)
EP (1) EP0726905B1 (de)
AT (1) ATE291583T1 (de)
AU (1) AU8132194A (de)
CA (1) CA2175695A1 (de)
DE (1) DE69434314T2 (de)
ES (1) ES2240970T3 (de)
WO (1) WO1995012607A1 (de)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU694187B2 (en) * 1994-02-07 1998-07-16 Beckman Coulter, Inc. Ligase/polymerase-mediated genetic bit analysis TM of single nucleotide polymorphisms and its use in genetic analysis
US5541322A (en) * 1994-10-14 1996-07-30 Glaxo Wellcome Inc. Synthesis of 6-azaandrostenones
US6391550B1 (en) 1996-09-19 2002-05-21 Affymetrix, Inc. Identification of molecular sequence signatures and methods involving the same
EP0941366A2 (de) * 1996-11-06 1999-09-15 Whitehead Institute For Biomedical Research Biallelische marker
US5830665A (en) * 1997-03-03 1998-11-03 Exact Laboratories, Inc. Contiguous genomic sequence scanning
US5888778A (en) * 1997-06-16 1999-03-30 Exact Laboratories, Inc. High-throughput screening method for identification of genetic mutations or disease-causing microorganisms using segmented primers
US6566101B1 (en) 1997-06-16 2003-05-20 Anthony P. Shuber Primer extension methods for detecting nucleic acids
US7105353B2 (en) 1997-07-18 2006-09-12 Serono Genetics Institute S.A. Methods of identifying individuals for inclusion in drug studies
EP0892068A1 (de) * 1997-07-18 1999-01-20 Genset Sa Verfahren zur Herstellung einer genetischen Karte des menschlichen Genoms mit hoher Dichte, basierend auf Linkage Disequilibrium
US6692909B1 (en) 1998-04-01 2004-02-17 Whitehead Institute For Biomedical Research Coding sequence polymorphisms in vascular pathology genes
WO1999053095A2 (en) * 1998-04-09 1999-10-21 Whitehead Institute For Biomedical Research Biallelic markers
US6537751B1 (en) 1998-04-21 2003-03-25 Genset S.A. Biallelic markers for use in constructing a high density disequilibrium map of the human genome
EP1071817A2 (de) * 1998-04-21 2001-01-31 Genset Biallelische marker zur verwendung in der herstellung von karten des menschlichen genoms mit hoher markerdichte
US6525185B1 (en) 1998-05-07 2003-02-25 Affymetrix, Inc. Polymorphisms associated with hypertension
US6703228B1 (en) 1998-09-25 2004-03-09 Massachusetts Institute Of Technology Methods and products related to genotyping and DNA analysis
US6403309B1 (en) 1999-03-19 2002-06-11 Valigen (Us), Inc. Methods for detection of nucleic acid polymorphisms using peptide-labeled oligonucleotides and antibody arrays
AU1477601A (en) * 1999-11-10 2001-06-06 Affymetrix, Inc. Genetic compositions and methods
AU2001245489A1 (en) * 2000-03-07 2001-09-17 Whitehead Institute For Biomedical Research Human single nucleotide polymorphisms
EP1182265A1 (de) * 2000-08-15 2002-02-27 Eidgenössische Technische Hochschule Zürich Methode zum Nachweis genetischer Merkmale verbesserter Zuchttierembryonen vor Implantation
US6428964B1 (en) 2001-03-15 2002-08-06 Exact Sciences Corporation Method for alteration detection
GB0111886D0 (en) * 2001-05-15 2001-07-04 Animal Health Trust Genetic typing
US20030129630A1 (en) * 2001-10-17 2003-07-10 Equigene Research Inc. Genetic markers associated with desirable and undesirable traits in horses, methods of identifying and using such markers
GB0205455D0 (en) 2002-03-07 2002-04-24 Molecular Sensing Plc Nucleic acid probes, their synthesis and use
AU2003247715B8 (en) * 2002-06-28 2008-06-05 Orchid Cellmark Inc. Methods and compositions for analyzing compromised samples using single nucleotide polymorphism panels
TW200413527A (en) 2002-10-29 2004-08-01 Riken Amplification of nucleic acid
CA2512110A1 (en) 2002-12-31 2004-07-22 Mmi Genomics, Inc. Compositions, methods, and systems for inferring bovine breed
US20050181394A1 (en) * 2003-06-20 2005-08-18 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20040259100A1 (en) * 2003-06-20 2004-12-23 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050053980A1 (en) 2003-06-20 2005-03-10 Illumina, Inc. Methods and compositions for whole genome amplification and genotyping
US20050014165A1 (en) * 2003-07-18 2005-01-20 California Pacific Medical Center Biomarker panel for colorectal cancer
WO2005040400A2 (en) * 2003-10-24 2005-05-06 Mmi Genomics, Inc. Methods and systems for inferring traits to manage non-beef livestock
WO2005063977A1 (ja) 2003-12-25 2005-07-14 Riken 核酸の増幅法およびこれを利用した変異核酸の検出法
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
WO2006123943A1 (en) 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
JP5592802B2 (ja) 2008-01-25 2014-09-17 セラノスティクス ラボラトリー 薬物応答を評価するための方法および組成物
CA2794248C (en) * 2010-03-24 2018-02-20 Glendon John Parker Methods for conducting genetic analysis using protein polymorphisms
EP2576823A1 (de) 2010-06-04 2013-04-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Konstitutiv aktive prolactin-rezeptorvarianten als prognostische marker und therapeutische ziele zur vorbeugung des fortschritts von hormonabhängigen karzinomen in richtung hormonunabhängigkeit
US20230120825A1 (en) * 2020-02-28 2023-04-20 Laboratory Corporation Of America Holdings Compositions, Methods, and Systems for Paternity Determination

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853936A1 (de) * 1978-12-14 1980-07-03 Bayer Ag Phosphonsaeureester
US4582788A (en) * 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
US4683194A (en) * 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GB8606719D0 (en) * 1986-03-19 1986-04-23 Lister Preventive Med Genetic probes
GB8612087D0 (en) * 1986-05-19 1986-06-25 Ici Plc Hybridisation probes
GB8810400D0 (en) * 1988-05-03 1988-06-08 Southern E Analysing polynucleotide sequences
WO1989010414A1 (en) * 1988-04-28 1989-11-02 Robert Bruce Wallace AMPLIFIED SEQUENCE POLYMORPHISMS (ASPs)
WO1990001069A1 (en) * 1988-07-20 1990-02-08 Segev Diagnostics, Inc. Process for amplifying and detecting nucleic acid sequences
GB2228086A (en) * 1988-11-25 1990-08-15 Ici Plc Characterisation of genomic DNA
IE66572B1 (en) * 1989-02-13 1996-01-24 Geneco Pty Ltd Detection of a nucleic acid sequence or a change therein
FR2650840B1 (fr) * 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
US5851762A (en) * 1990-07-11 1998-12-22 Gene Type Ag Genomic mapping method by direct haplotyping using intron sequence analysis
US5234811A (en) * 1991-09-27 1993-08-10 The Scripps Research Institute Assay for a new gaucher disease mutation
JP3643375B2 (ja) * 1990-12-06 2005-04-27 エフ．ホフマン ― ラ ロシュ アーゲー ＨＬＡ ＤＲβのＤＮＡタイピングのための方法および試薬
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
WO1992016657A1 (en) * 1991-03-13 1992-10-01 E.I. Du Pont De Nemours And Company Method of identifying a nucleotide present at a defined position in a nucleic acid
US5266459A (en) * 1992-02-24 1993-11-30 The Scripps Research Institute Gaucher's disease: detection of a new mutation in intron 2 of the glucocerebrosidase gene
US5429923A (en) * 1992-12-11 1995-07-04 President And Fellows Of Harvard College Method for detecting hypertrophic cardiomyophathy associated mutations

Also Published As

Publication number Publication date
US20020094525A1 (en) 2002-07-18
ATE291583T1 (de) 2005-04-15
US20030170624A1 (en) 2003-09-11
WO1995012607A1 (en) 1995-05-11
CA2175695A1 (en) 1995-05-11
DE69434314T2 (de) 2006-03-30
ES2240970T3 (es) 2005-10-16
EP0726905A4 (de) 1997-12-17
AU8132194A (en) 1995-05-23
EP0726905A1 (de) 1996-08-21
EP0726905B1 (de) 2005-03-23

Similar Documents

Publication Publication Date Title
DE69434314D1 (de) Polymorphismus von mononukleotiden und ihre verwendung in der genanalyse
ATE325892T1 (de) Multiparameter fluoreszenz in situ hybridisierung
DE69333073D1 (de) Verwendungen von fluoreszierenden n-nukleosiden und dessen analogen
DE69724209D1 (de) Erkennung einer genetischen prädisposition fur osteoporose
ATE225406T1 (de) Ein screeningsystem auf zellbasis
DE59310281D1 (de) Verfahren zur präparierung und hybridisierung von spezifischen proben
ATE191934T1 (de) Verfahren zur isothermer amplifikation von nukleinsäure molekülen
IL147793A0 (en) Optical system analysis of cells
DE69531542D1 (de) Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse
DE69835010D1 (de) Feststellung von endometriumkrebs
DE69829860D1 (de) Spezies-übergreifendes anfärben von chromosomen
FI956052A (fi) Salmonellan tunnistus polymeraasiketjureaktorilla
IL139163A (en) Method of predicting the ability of compounds to modulate the biological activity of receptors
DE69637579D1 (de) Methode zur Amplifizierung von Nukleinsäure und entsprechende Regenzien dafür
DE69418284T2 (de) Vorrichtung zur analyse von haptenen und ihre verwendung
ES2175095T3 (es) Marcadores de adn respecto al tamaño de una camada de cerdos.
DE69628449D1 (de) Verfahren zur identifizierung unbekannter allele
DE69709804D1 (de) Nachweis von nukleotidsequenzen durch signalamplifizierung
DE69030804T2 (de) Reagenzien zur verbesserung von hybridisierung
ATE357516T1 (de) Modulation molekularer wechselwirkungspositionen in rns und anderen biomolekülen
ATE301189T1 (de) Neues verfahren zum nachweis von cryptosporidium
BR9814866A (pt) Uso de oligÈmeros de ácido poliamida nucléicopara produzir uma resposta biológica
AU2514999A (en) Mood disorder gene

Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee
8327 Change in the person/name/address of the patent owner

Owner name: ORCHID CELLMARK INC., PRINCETON, N.J., US

8370 Indication related to discontinuation of the patent is to be deleted
8331 Complete revocation