DE69431285D1 - Herstellungsmethode von markierten genen; transcripten und proteinen - Google Patents

Herstellungsmethode von markierten genen; transcripten und proteinen

Info

Publication number
DE69431285D1
DE69431285D1 DE69431285T DE69431285T DE69431285D1 DE 69431285 D1 DE69431285 D1 DE 69431285D1 DE 69431285 T DE69431285 T DE 69431285T DE 69431285 T DE69431285 T DE 69431285T DE 69431285 D1 DE69431285 D1 DE 69431285D1
Authority
DE
Germany
Prior art keywords
transcripts
proteins
producing marked
marked genes
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69431285T
Other languages
English (en)
Other versions
DE69431285T2 (de
Inventor
Jonathan Wallace Jarvik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of DE69431285D1 publication Critical patent/DE69431285D1/de
Application granted granted Critical
Publication of DE69431285T2 publication Critical patent/DE69431285T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1065—Preparation or screening of tagged libraries, e.g. tagged microorganisms by STM-mutagenesis, tagged polynucleotides, gene tags
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
    • C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
DE69431285T 1993-01-05 1994-01-05 Herstellungsmethode von markierten genen; transcripten und proteinen Expired - Fee Related DE69431285T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/000,619 US5652128A (en) 1993-01-05 1993-01-05 Method for producing tagged genes, transcripts, and proteins
PCT/US1994/000254 WO1994016092A1 (en) 1993-01-05 1994-01-05 Method for producing tagged genes, transcripts, and proteins

Publications (2)

Publication Number Publication Date
DE69431285D1 true DE69431285D1 (de) 2002-10-10
DE69431285T2 DE69431285T2 (de) 2003-07-31

Family

ID=21692289

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69431285T Expired - Fee Related DE69431285T2 (de) 1993-01-05 1994-01-05 Herstellungsmethode von markierten genen; transcripten und proteinen

Country Status (5)

Country Link
US (5) US5652128A (de)
EP (1) EP0656954B1 (de)
DE (1) DE69431285T2 (de)
ES (1) ES2181714T3 (de)
WO (1) WO1994016092A1 (de)

Families Citing this family (50)

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US5652128A (en) * 1993-01-05 1997-07-29 Jarvik; Jonathan Wallace Method for producing tagged genes, transcripts, and proteins
US5789655A (en) * 1994-05-13 1998-08-04 The Regents Of The University Of California Transgenic animals expressing artificial epitope-tagged proteins
AUPN480095A0 (en) * 1995-08-15 1995-09-07 Commonwealth Scientific And Industrial Research Organisation Epitope tagging system
US5866330A (en) * 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US5695937A (en) * 1995-09-12 1997-12-09 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US6346392B1 (en) * 1996-11-27 2002-02-12 Smithkline Beecham Corporation Polynucleotides encoding a novel glutamine transport ATP-binding protein
US5928888A (en) * 1996-09-26 1999-07-27 Aurora Biosciences Corporation Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and secondary screening capabilities
US7332338B2 (en) 1996-10-04 2008-02-19 Lexicon Pharmaceuticals, Inc. Vectors for making genomic modifications
US20040072243A1 (en) * 1996-10-11 2004-04-15 Lexicon Genetics Incorporated Indexed library of cells containing genomic modifications and methods of making and utilizing the same
AU5168598A (en) * 1996-11-08 1998-05-29 Jonathan W. Jarvik Method for producing tagged genes, transcripts and proteins
US5948677A (en) * 1996-12-09 1999-09-07 Jarvik; Jonathan W. Reading frame independent epitope tagging
CA2205888A1 (en) 1997-07-11 1999-01-11 John J. Priatel Complementation trap
CA2224475A1 (en) * 1998-02-25 1999-08-25 University Of British Columbia Protein interaction and transcription factor trap
CA2263784A1 (en) 1998-03-23 1999-09-23 Megabios Corporation Dual-tagged proteins and their uses
US6436707B1 (en) * 1998-03-27 2002-08-20 Lexicon Genetics Incorporated Vectors for gene mutagenesis and gene discovery
US6808921B1 (en) * 1998-03-27 2004-10-26 Lexicon Genetics Incorporated Vectors for gene mutagenesis and gene discovery
US6498286B1 (en) 1998-08-20 2002-12-24 Ffr Cooperative Germplasm containing an identifier nucleotide sequence and method for identifying germplasm
EP1165775A2 (de) 1999-03-05 2002-01-02 Maxygen, Inc. Rekombination von insertionsmodifizierten nucleinsäuren
MXPA02003232A (es) * 1999-09-30 2003-09-22 Alexion Pharma Inc Composiciones y metodos para alternar la expresion de genes.
US7816098B2 (en) * 2000-01-31 2010-10-19 Sense Proteomic Limited Methods of making and using a protein array
JP4730804B2 (ja) * 2000-01-31 2011-07-20 センス・プロテオミック・リミテッド 方法
US6897020B2 (en) * 2000-03-20 2005-05-24 Newlink Genetics Inc. Methods and compositions for elucidating relative protein expression levels in cells
US20060134629A1 (en) * 2000-03-20 2006-06-22 Link Charles J Methods and compositions for elucidating protein expression profiles in cells
ATE344456T1 (de) * 2000-05-05 2006-11-15 Purdue Research Foundation Durch affinität ausgewählte unterschriftspeptide zur identifizierung und quantifizierung von proteinen
JP2002142765A (ja) * 2000-07-14 2002-05-21 Tosoh Corp 新規ゲノム解析法
EP1301632A2 (de) * 2000-07-19 2003-04-16 Pointilliste, Inc. Eingebettetes sortieren und hochdurchsatzscreening
AU8337701A (en) * 2000-08-14 2002-02-25 Us Health Enhanced homologous recombination mediated by lambda recombination proteins
US6821747B2 (en) 2001-07-12 2004-11-23 Automated Cell, Inc. Suppression of non-biological motion
US20030143612A1 (en) * 2001-07-18 2003-07-31 Pointilliste, Inc. Collections of binding proteins and tags and uses thereof for nested sorting and high throughput screening
EP1432992A2 (de) * 2001-09-27 2004-06-30 Purdue Research Foundation Kontrolle von isotopeneffekten während der analytfraktionierung
EP1474504A2 (de) * 2002-01-24 2004-11-10 Pointilliste, Inc. Verwendung von sammlungen von bindungsstellen für die probenprofilierung und andere anwendungen
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
EP1585806A2 (de) * 2002-10-30 2005-10-19 Pointilliste, Inc. Verfahren zur herstellung von kollektionen mit polypeptid-tag und die polypeptide mit tag enthaltende einfangsysteme
EP1597577A4 (de) * 2003-02-10 2007-02-21 Pointilliste Inc Selbstanordnende arrays und ihre anwendung
WO2005012497A2 (en) * 2003-07-29 2005-02-10 Trellis Bioscience, Inc. Translocation tagging
WO2005026686A2 (en) * 2003-09-09 2005-03-24 Compass Genetics, Llc Multiplexed analytical platform
WO2005029040A2 (en) * 2003-09-18 2005-03-31 Parallele Biosciences, Inc. System and methods for enhancing signal-to-noise ratios of microarray-based measurements
CN1860232A (zh) * 2003-09-30 2006-11-08 莱克康遗传公司 鉴别基因功能的方法和组合物
US20050095648A1 (en) * 2003-10-30 2005-05-05 Mario Geysen Method for designing linear epitopes and algorithm therefor and polypeptide epitopes
WO2005067980A2 (en) * 2004-01-12 2005-07-28 Pointilliste, Inc. Design of therapeutics and therapeutics
EP1713936B1 (de) * 2004-02-12 2009-12-09 Population Genetics Technologies Ltd Corporation of Great Britain Genetische analyse mittels sequenzspezifischem sortieren
EP2412816B1 (de) 2004-07-26 2014-12-03 Pfenex Inc. Verfahren zur verbesserten Proteinexpression durch Strain-Engineering
US7407757B2 (en) * 2005-02-10 2008-08-05 Population Genetics Technologies Genetic analysis by sequence-specific sorting
WO2006099604A2 (en) * 2005-03-16 2006-09-21 Compass Genetics, Llc Methods and compositions for assay readouts on multiple analytical platforms
CA2617930A1 (en) 2005-08-09 2007-03-29 Revivicor, Inc. Transgenic ungulates expressing ctla4-ig and uses thereof
US20090149338A1 (en) * 2005-09-30 2009-06-11 Hughes Thomas E System for detecting protein-protein interactions
JP5444553B2 (ja) 2007-04-27 2014-03-19 フェネックス インコーポレイテッド 微生物宿主を迅速にスクリーニングして、異種タンパク質発現の収率および／または質が改善されている特定の株を同定する方法
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
WO2009093242A2 (en) * 2008-01-24 2009-07-30 Yeda Research And Development Co. Ltd. Cell populations for polypeptide analysis and uses of same
US9695416B2 (en) 2012-07-18 2017-07-04 Siemens Healthcare Diagnostics Inc. Method of normalizing biological samples

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0451700A1 (de) * 1990-04-10 1991-10-16 Miles Inc. Rekombinante APP Minigene zur Expression in Transgen-Mäusen als Alzheimer-Krankheitsmuster
DE4021458C1 (de) * 1990-07-05 1991-08-29 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften Ev, 3400 Goettingen, De
WO1992013071A1 (en) * 1991-01-28 1992-08-06 Massachusetts Institute Of Technology Method of exon amplification
US5652128A (en) * 1993-01-05 1997-07-29 Jarvik; Jonathan Wallace Method for producing tagged genes, transcripts, and proteins

Also Published As

Publication number Publication date
EP0656954B1 (de) 2002-09-04
US5916810A (en) 1999-06-29
WO1994016092A1 (en) 1994-07-21
EP0656954A1 (de) 1995-06-14
US6080541A (en) 2000-06-27
EP0656954A4 (de) 1997-04-09
US5652128A (en) 1997-07-29
US6472207B1 (en) 2002-10-29
US6096717A (en) 2000-08-01
DE69431285T2 (de) 2003-07-31
ES2181714T3 (es) 2003-03-01

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee