DE69429310D1 - Verfahren zum Nachweis des bakteriellen Wachstums einer Vielzahl in Kulturfläschchen - Google Patents
Verfahren zum Nachweis des bakteriellen Wachstums einer Vielzahl in KulturfläschchenInfo
- Publication number
- DE69429310D1 DE69429310D1 DE69429310T DE69429310T DE69429310D1 DE 69429310 D1 DE69429310 D1 DE 69429310D1 DE 69429310 T DE69429310 T DE 69429310T DE 69429310 T DE69429310 T DE 69429310T DE 69429310 D1 DE69429310 D1 DE 69429310D1
- Authority
- DE
- Germany
- Prior art keywords
- detection
- large number
- bacterial growth
- culture vials
- vials
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 230000001580 bacterial effect Effects 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
- G01N21/253—Colorimeters; Construction thereof for batch operation, i.e. multisample apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/46—Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N2021/7769—Measurement method of reaction-produced change in sensor
- G01N2021/7786—Fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/04—Batch operation; multisample devices
- G01N2201/0438—Linear motion, sequential
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2201/00—Features of devices classified in G01N21/00
- G01N2201/10—Scanning
- G01N2201/101—Scanning measuring head
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/028—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having reaction cells in the form of microtitration plates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/808—Optical sensing apparatus
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/113,444 US5397709A (en) | 1993-08-27 | 1993-08-27 | System for detecting bacterial growth in a plurality of culture vials |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69429310D1 true DE69429310D1 (de) | 2002-01-17 |
DE69429310T2 DE69429310T2 (de) | 2002-07-18 |
Family
ID=22349453
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69429310T Expired - Fee Related DE69429310T2 (de) | 1993-08-27 | 1994-08-16 | Verfahren zum Nachweis des bakteriellen Wachstums einer Vielzahl in Kulturfläschchen |
Country Status (6)
Country | Link |
---|---|
US (2) | US5397709A (de) |
EP (1) | EP0640826B1 (de) |
JP (1) | JPH0829116B2 (de) |
AU (1) | AU679078B2 (de) |
CA (1) | CA2130014C (de) |
DE (1) | DE69429310T2 (de) |
Families Citing this family (146)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5858769A (en) * | 1989-05-15 | 1999-01-12 | Akzo Nobel N.V. | Device for detecting microorganisms |
CA2156281A1 (en) * | 1993-02-17 | 1994-09-01 | Anthony Hugh Carr | Improvements in or relating to monitoring |
US5580784A (en) * | 1993-09-29 | 1996-12-03 | Becton Dickinson And Company | Data collection apparatus for use with chemical sensors |
US6387651B1 (en) | 1995-04-12 | 2002-05-14 | Biolog, Inc. | Comparative phenotype analysis of two or more microorganisms using a plurality of substrates within a microwell device |
US6352854B1 (en) | 1995-04-25 | 2002-03-05 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US5925562A (en) * | 1995-04-25 | 1999-07-20 | Irori | Remotely programmable matrices with memories |
US6416714B1 (en) | 1995-04-25 | 2002-07-09 | Discovery Partners International, Inc. | Remotely programmable matrices with memories |
US5961923A (en) * | 1995-04-25 | 1999-10-05 | Irori | Matrices with memories and uses thereof |
US6319668B1 (en) | 1995-04-25 | 2001-11-20 | Discovery Partners International | Method for tagging and screening molecules |
US6331273B1 (en) | 1995-04-25 | 2001-12-18 | Discovery Partners International | Remotely programmable matrices with memories |
US6017496A (en) | 1995-06-07 | 2000-01-25 | Irori | Matrices with memories and uses thereof |
US5874214A (en) | 1995-04-25 | 1999-02-23 | Irori | Remotely programmable matrices with memories |
US6025129A (en) * | 1995-04-25 | 2000-02-15 | Irori | Remotely programmable matrices with memories and uses thereof |
US6340588B1 (en) * | 1995-04-25 | 2002-01-22 | Discovery Partners International, Inc. | Matrices with memories |
US5741462A (en) | 1995-04-25 | 1998-04-21 | Irori | Remotely programmable matrices with memories |
US5891739A (en) * | 1995-06-27 | 1999-04-06 | Becton Dickinson And Company | Multiple sample container |
CA2179364C (en) * | 1995-06-27 | 1999-09-28 | Klaus W. Berndt | Method and apparatus for detecting microorganisms |
US6048734A (en) | 1995-09-15 | 2000-04-11 | The Regents Of The University Of Michigan | Thermal microvalves in a fluid flow method |
US5798514A (en) * | 1996-01-11 | 1998-08-25 | Accumed Inc. | Circular bar code |
US5705384A (en) * | 1996-05-16 | 1998-01-06 | Becton Dickinson And Company | Compact high-volume microorganism detection apparatus |
GB2313188B (en) * | 1996-05-17 | 1999-10-20 | Pfizer Ltd | Spectrophotometric analysis |
US6171554B1 (en) * | 1996-10-02 | 2001-01-09 | Matrix Technologies Corporation | Apparatus and method for alphanumerically identifying and arranging test tubes |
US6166761A (en) * | 1997-01-09 | 2000-12-26 | Interface Multigrad Technology | Method and apparatus for monitoring a biological sample |
GB9714347D0 (en) * | 1997-07-09 | 1997-09-10 | Oxoid Ltd | Image analysis systems and devices for use therewith |
US5922617A (en) * | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
DE1075328T1 (de) * | 1998-05-01 | 2001-10-11 | Ammann Kelly G | Automatische diagnostische analysevorrichtung und -verfahren |
EP0953838A1 (de) * | 1998-05-01 | 1999-11-03 | F. Hoffmann-La Roche Ag | Vorrichtung zur gleichzeitigen Überwachung von in einer Mehrzahl von Reaktionsgefässen stattfindenden Reaktionen |
AU759974B2 (en) * | 1998-05-16 | 2003-05-01 | Applied Biosystems, Llc | Instrument for monitoring polymerase chain reaction of DNA |
US6818437B1 (en) * | 1998-05-16 | 2004-11-16 | Applera Corporation | Instrument for monitoring polymerase chain reaction of DNA |
US7498164B2 (en) | 1998-05-16 | 2009-03-03 | Applied Biosystems, Llc | Instrument for monitoring nucleic acid sequence amplification reaction |
EP1080364B1 (de) * | 1998-05-19 | 2002-11-20 | Cepheid | Mehrkanaliges optisches detektionssystem |
GB9818176D0 (en) | 1998-08-21 | 1998-10-14 | Aromascan Plc | Method for detecting microorganisms |
FR2784189B3 (fr) | 1998-10-05 | 2000-11-03 | Commissariat Energie Atomique | Biopuce et dispositif de lecture d'une biopuce comportant une pluralite de zones de reconnaissance moleculaire |
FR2784188B1 (fr) * | 1998-10-05 | 2000-12-22 | Commissariat Energie Atomique | Biopuce et dispositif de lecture d'une biopuce comportant une pluralite de zones de reconnaissance moleculaire |
EP1147394A1 (de) * | 1998-12-15 | 2001-10-24 | Union Carbide Chemicals & Plastics Technology Corporation | Vorrichtung und verfahren zur kombinatorischen chemischen analyse |
US6271022B1 (en) * | 1999-03-12 | 2001-08-07 | Biolog, Inc. | Device for incubating and monitoring multiwell assays |
US6251624B1 (en) * | 1999-03-12 | 2001-06-26 | Akzo Nobel N.V. | Apparatus and method for detecting, quantifying and characterizing microorganisms |
NL1011664C2 (nl) * | 1999-03-24 | 2000-05-15 | Datascan Group B V | Inrichting en werkwijze voor het selecteren en vastleggen van een beeld dat een deel vormt van een bestraald of emitterend object. |
JP3597729B2 (ja) * | 1999-05-11 | 2004-12-08 | 日立ソフトウエアエンジニアリング株式会社 | 蛍光測光方法及び蛍光測光装置 |
JP3815969B2 (ja) * | 1999-05-12 | 2006-08-30 | アクララ バイオサイエンシーズ, インコーポレイテッド | 微量流体デバイスにおける多重方式蛍光検出 |
US7387891B2 (en) * | 1999-05-17 | 2008-06-17 | Applera Corporation | Optical instrument including excitation source |
US20050279949A1 (en) * | 1999-05-17 | 2005-12-22 | Applera Corporation | Temperature control for light-emitting diode stabilization |
US7410793B2 (en) * | 1999-05-17 | 2008-08-12 | Applera Corporation | Optical instrument including excitation source |
US7423750B2 (en) * | 2001-11-29 | 2008-09-09 | Applera Corporation | Configurations, systems, and methods for optical scanning with at least one first relative angular motion and at least one second angular motion or at least one linear motion |
US6696239B1 (en) | 2000-04-20 | 2004-02-24 | Biolog, Inc. | Comparative phenotype analysis for assessment of biological active compounds such as antimicrobials |
US6563581B1 (en) | 2000-07-14 | 2003-05-13 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
US20030160957A1 (en) * | 2000-07-14 | 2003-08-28 | Applera Corporation | Scanning system and method for scanning a plurality of samples |
EP1309719B2 (de) | 2000-08-14 | 2022-09-07 | University of Maryland at Baltimore County | Bioreaktor und bioverfahrenstechnik |
US6692700B2 (en) | 2001-02-14 | 2004-02-17 | Handylab, Inc. | Heat-reduction methods and systems related to microfluidic devices |
US8895311B1 (en) | 2001-03-28 | 2014-11-25 | Handylab, Inc. | Methods and systems for control of general purpose microfluidic devices |
US6852287B2 (en) | 2001-09-12 | 2005-02-08 | Handylab, Inc. | Microfluidic devices having a reduced number of input and output connections |
US7829025B2 (en) | 2001-03-28 | 2010-11-09 | Venture Lending & Leasing Iv, Inc. | Systems and methods for thermal actuation of microfluidic devices |
US7010391B2 (en) | 2001-03-28 | 2006-03-07 | Handylab, Inc. | Methods and systems for control of microfluidic devices |
US7323140B2 (en) | 2001-03-28 | 2008-01-29 | Handylab, Inc. | Moving microdroplets in a microfluidic device |
US7635588B2 (en) * | 2001-11-29 | 2009-12-22 | Applied Biosystems, Llc | Apparatus and method for differentiating multiple fluorescence signals by excitation wavelength |
EP2775291B1 (de) | 2002-05-17 | 2016-01-13 | Life Technologies Corporation | Vorrichtung zur Unterscheidung mehrerer Fluoreszenzsignale anhand ihrer Anregungswellenlänge |
KR101186271B1 (ko) | 2002-06-26 | 2012-09-27 | 애버리 데니슨 코포레이션 | 폴리프로필렌/올레핀 탄성체 혼합물을 포함하는 배향된필름 |
AU2003207980A1 (en) * | 2002-06-27 | 2004-01-19 | I.M.T. Interface Multigrad Technology Ltd. | Changing the temperature of a liquid sample and a receptacle useful therefor |
US7148043B2 (en) | 2003-05-08 | 2006-12-12 | Bio-Rad Laboratories, Inc. | Systems and methods for fluorescence detection with a movable detection module |
JP2005006553A (ja) * | 2003-06-19 | 2005-01-13 | Olympus Corp | 細胞培養検出装置 |
GB2423151B (en) * | 2003-07-23 | 2007-05-09 | Essen Instr Inc | Examination systems for biological samples |
EP2402089A1 (de) | 2003-07-31 | 2012-01-04 | Handylab, Inc. | Verarbeitung partikelhaltiger Proben |
US20050127279A1 (en) * | 2003-08-15 | 2005-06-16 | Harris Martin R. | Multiplexed fiber optic sensor system |
US7067323B2 (en) * | 2003-10-15 | 2006-06-27 | Lighthouse Instruments, Llc | System and method for automated headspace analysis |
JP2007522801A (ja) | 2004-01-07 | 2007-08-16 | リーブテック,インコーポレイテッド | 一体のスパージャーとセンサー受け器を有する混合用袋 |
DE102004017039A1 (de) * | 2004-04-02 | 2005-11-03 | Rwth Aachen | Verfahren und Vorrichtung zur Erfassung von Prozessparametern von Reaktionsflüssigkeiten in mehreren geschüttelten Mikroreaktoren |
WO2005108620A2 (en) | 2004-05-03 | 2005-11-17 | Handylab, Inc. | Processing polynucleotide-containing samples |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
JP4767536B2 (ja) * | 2004-12-28 | 2011-09-07 | オリンパス株式会社 | 培養観察装置 |
US7310147B2 (en) * | 2005-01-27 | 2007-12-18 | Genetix Limited | Robotic apparatus for picking of cells and other applications with integrated spectroscopic capability |
US20060166305A1 (en) * | 2005-01-27 | 2006-07-27 | Genetix Limited | Animal cell confluence detection method and apparatus |
CA2842232C (en) * | 2005-03-10 | 2015-01-27 | Gen-Probe Incorporated | Systems and methods to perform assays for detecting or quantifying analytes within samples |
US7888125B2 (en) | 2005-05-09 | 2011-02-15 | Theranos, Inc. | Calibration of fluidic devices |
WO2007044917A2 (en) * | 2005-10-11 | 2007-04-19 | Handylab, Inc. | Polynucleotide sample preparation device |
US7727473B2 (en) | 2005-10-19 | 2010-06-01 | Progentech Limited | Cassette for sample preparation |
US7754148B2 (en) | 2006-12-27 | 2010-07-13 | Progentech Limited | Instrument for cassette for sample preparation |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8088616B2 (en) * | 2006-03-24 | 2012-01-03 | Handylab, Inc. | Heater unit for microfluidic diagnostic system |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
JP5415253B2 (ja) * | 2006-03-24 | 2014-02-12 | ハンディラブ・インコーポレーテッド | 微小流体サンプルを処理するための一体化システム及びその使用方法 |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
US8012744B2 (en) | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
WO2008060604A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
WO2008061165A2 (en) | 2006-11-14 | 2008-05-22 | Handylab, Inc. | Microfluidic cartridge and method of making same |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
USD621060S1 (en) | 2008-07-14 | 2010-08-03 | Handylab, Inc. | Microfluidic cartridge |
CA2693654C (en) | 2007-07-13 | 2018-02-13 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8133671B2 (en) | 2007-07-13 | 2012-03-13 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
AU2013205266B2 (en) * | 2007-07-13 | 2015-06-11 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
US9618139B2 (en) | 2007-07-13 | 2017-04-11 | Handylab, Inc. | Integrated heater and magnetic separator |
US20090136385A1 (en) | 2007-07-13 | 2009-05-28 | Handylab, Inc. | Reagent Tube |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
SG10201606120XA (en) | 2007-10-02 | 2016-09-29 | Theranos Inc | Modular Point-Of-Care Devices And Uses Thereof |
US20100314447A1 (en) * | 2007-10-17 | 2010-12-16 | Agilent Technologies, Inc. | Measurement device with motion-triggered data exchange |
WO2009103003A2 (en) * | 2008-02-15 | 2009-08-20 | Bio-Rad Laboratories, Inc. | Scanning fluorescent reader with diffuser system |
US20100009351A1 (en) * | 2008-07-11 | 2010-01-14 | Handylab, Inc. | Polynucleotide Capture Materials, and Method of Using Same |
USD618820S1 (en) | 2008-07-11 | 2010-06-29 | Handylab, Inc. | Reagent holder |
USD787087S1 (en) | 2008-07-14 | 2017-05-16 | Handylab, Inc. | Housing |
WO2010132749A2 (en) | 2009-05-15 | 2010-11-18 | Biomerieux, Inc. | Automated transfer mechanism for microbial. detection apparatus |
US9574219B2 (en) | 2009-05-15 | 2017-02-21 | Biomerieux, Inc. | Device for sampling a specimen container |
CN105825049A (zh) | 2009-10-19 | 2016-08-03 | 提拉诺斯公司 | 集成的健康数据采集和分析系统 |
WO2011106384A1 (en) | 2010-02-23 | 2011-09-01 | Genturadx, Inc. | Apparatus and methods for integrated sample preparation, reaction and detection |
AU2010354100B2 (en) | 2010-05-14 | 2015-07-09 | Biomerieux, Inc. | Identification and/or characterization of a microbial agent using taxonomic hierarchical classification |
CN103540518B (zh) | 2010-07-23 | 2015-07-08 | 贝克曼考尔特公司 | 化验盒 |
US9046507B2 (en) | 2010-07-29 | 2015-06-02 | Gen-Probe Incorporated | Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure |
CN106248582B (zh) | 2011-01-21 | 2020-10-20 | 拉布拉多诊断有限责任公司 | 样品使用最大化的系统和方法 |
CN103403533B (zh) | 2011-02-24 | 2017-02-15 | 简.探针公司 | 用于分辨光信号检测器中不同调制频率的光信号的系统和方法 |
CA3082652A1 (en) | 2011-04-15 | 2012-10-18 | Becton, Dickinson And Company | Scanning real-time microfluidic thermocycler and methods for synchronized thermocycling and scanning optical detection |
WO2012151473A2 (en) | 2011-05-04 | 2012-11-08 | Luminex Corporation | Apparatus and methods for integrated sample preparation, reaction and detection |
US9121827B2 (en) | 2011-06-30 | 2015-09-01 | Mocon, Inc. | Method of contemporaneously monitoring changes in analyte concentration in a plurality of samples on individual schedules |
WO2013023697A1 (en) * | 2011-08-17 | 2013-02-21 | Luxcel Biosciences Limited | Tool and method for validating operational performance of a photoluminesence based analytical instrument |
DK2761305T3 (da) | 2011-09-30 | 2017-11-20 | Becton Dickinson Co | Forenet reagensstrimmel |
USD692162S1 (en) | 2011-09-30 | 2013-10-22 | Becton, Dickinson And Company | Single piece reagent holder |
EP2773892B1 (de) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Vorrichtung zur vorbereitung von polynukleotidproben |
KR20140091033A (ko) | 2011-11-07 | 2014-07-18 | 베크만 컬터, 인코포레이티드 | 검체 컨테이너 검출 |
BR112014011046A2 (pt) | 2011-11-07 | 2017-06-13 | Beckman Coulter, Inc. | fluxo de trabalho e sistema de centrífuga |
WO2013070754A1 (en) | 2011-11-07 | 2013-05-16 | Beckman Coulter, Inc. | Robotic arm |
CN104053997B (zh) | 2011-11-07 | 2016-12-21 | 贝克曼考尔特公司 | 用于处理样本的系统和方法 |
WO2013070740A1 (en) | 2011-11-07 | 2013-05-16 | Beckman Coulter, Inc. | Aliquotter system and workflow |
US8973736B2 (en) | 2011-11-07 | 2015-03-10 | Beckman Coulter, Inc. | Magnetic damping for specimen transport system |
RU2658773C2 (ru) | 2012-02-03 | 2018-06-22 | Бектон, Дикинсон Энд Компани | Система и способ выполнения автоматизированных тестов над множеством биологических проб |
CA2804843C (en) * | 2012-02-06 | 2021-02-02 | Ortho-Clinical Diagnostics, Inc. | Multiple time windows for extending the range of an assay |
US10475527B2 (en) | 2012-03-22 | 2019-11-12 | Biomerieux, Inc. | Method and system for detection of microbial growth in a specimen container |
US8935001B2 (en) | 2012-03-29 | 2015-01-13 | bioMeriéux, Inc. | System and method for establishing and/or maintaining proper alignment of a robotic transfer mechanism |
KR102055611B1 (ko) * | 2012-08-17 | 2019-12-13 | 넥서스 디엑스, 아이엔씨. | 테스트 플랫폼, 검사장치 및 그 제어방법 |
WO2014086411A1 (en) | 2012-12-05 | 2014-06-12 | Luxcel Biosciences Limited | Individually and flexibly deployable target-analyte sensitive particulate probes and method of making and using |
US9684005B2 (en) * | 2013-12-06 | 2017-06-20 | BL Photonics Inc. | Apparatus and method for spectroscopic analysis of vinification liquids using coded sample containers |
EP4056380B1 (de) | 2014-10-21 | 2024-04-03 | Gen-Probe Incorporated | Verfahren und vorrichtung zum drucken auf einem gegenstand mit einer gekrümmten oberfläche |
WO2017205748A1 (en) | 2016-05-27 | 2017-11-30 | Biomerieux, Inc. | System and method of load balancing speciment containers within detection instruments |
WO2017205763A1 (en) | 2016-05-27 | 2017-11-30 | Biomerieux, Inc. | System and method for transferring specimen containers between detection instruments |
US11249021B2 (en) * | 2016-06-30 | 2022-02-15 | Esco Medical Aps | Apparatus for the incubation of a biological material |
JP6698451B2 (ja) * | 2016-07-11 | 2020-05-27 | オリンパス株式会社 | 観察装置 |
JP6815787B2 (ja) * | 2016-08-09 | 2021-01-20 | オリンパス株式会社 | 観察装置、観察装置の制御方法及び観察装置の制御プログラム |
DE102016116377A1 (de) | 2016-09-01 | 2018-03-01 | Rheinisch-Westfälisch Technische Hochschule (RWTH) Aachen | Verfahren und Vorrichtung zur Erfassung von Prozessparametern in Flüssigkulturen |
US10427162B2 (en) | 2016-12-21 | 2019-10-01 | Quandx Inc. | Systems and methods for molecular diagnostics |
WO2018206746A1 (en) | 2017-05-10 | 2018-11-15 | Luxcel Biosciences Limited | Real-time cellular or pericellular microenvironmental oxygen control |
CN110621586A (zh) | 2017-05-16 | 2019-12-27 | 安捷伦科技有限公司 | 消除顶空的微量滴定板盖以及通过盖光学地测量孔氧气浓度的方法 |
WO2022256580A1 (en) * | 2021-06-02 | 2022-12-08 | Richard Postrel | Instant bio-sensing for the detection of early onset diseases |
WO2023196546A1 (en) | 2022-04-08 | 2023-10-12 | Agilent Technologies, Inc. | Headspace eliminating microtiter plate lid |
WO2023196547A1 (en) | 2022-04-08 | 2023-10-12 | Agilent Technologies, Inc. | Microtiter plate lid and magnetic adapter |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3781120A (en) * | 1970-09-14 | 1973-12-25 | Technicon Instr | Self-locating sample receptacle having integral identification label |
US3773426A (en) * | 1972-02-22 | 1973-11-20 | Department Of Health Educ Welf | Bacterial growth detector |
CA1020068A (en) * | 1975-06-10 | 1977-11-01 | Edward T. Sheaff | Device for examining biological specimens |
US4115010A (en) * | 1976-02-03 | 1978-09-19 | Merck & Co., Inc. | Automated plate reader |
US4116775A (en) * | 1976-05-03 | 1978-09-26 | Mcdonnell Douglas Corporation | Machine and process for reading cards containing medical specimens |
FR2368709A1 (fr) * | 1976-10-19 | 1978-05-19 | Pasteur Institut | Photometre automatique |
US4349510A (en) * | 1979-07-24 | 1982-09-14 | Seppo Kolehmainen | Method and apparatus for measurement of samples by luminescence |
EP0025350A3 (de) * | 1979-09-05 | 1981-06-10 | Dynatech Ag | Apparat zum Feststellen von Lumineszenz-Reaktionen |
JPS57132038A (en) * | 1981-02-10 | 1982-08-16 | Olympus Optical Co Ltd | Photometric device |
US4397560A (en) * | 1981-04-23 | 1983-08-09 | Bio-Tek Instruments, Inc. | Photometer with microtray well position indicator |
AU566435B2 (en) * | 1983-12-05 | 1987-10-22 | Becton Dickinson & Company | Identification of microorganisms by infrared analysis of evolved carbon dioxide |
US4657870A (en) * | 1984-04-23 | 1987-04-14 | Ryder International Corporation | Incubator optical system for viewing sterilization indicator |
DE3420760A1 (de) * | 1984-06-04 | 1985-12-05 | Bayer Ag, 5090 Leverkusen | Beleuchtungseinrichtung fuer die optische, insbesondere bildanalytische auswertung von mikrobiologischen objekten |
US4772453A (en) * | 1985-03-01 | 1988-09-20 | Lisenbee Wayne F | Luminiscence measurement arrangement |
US5096807A (en) * | 1985-03-06 | 1992-03-17 | Murex Corporation | Imaging immunoassay detection system with background compensation and its use |
US4678894A (en) * | 1985-04-18 | 1987-07-07 | Baxter Travenol Laboratories, Inc. | Sample identification system |
CH669851A5 (de) * | 1986-03-06 | 1989-04-14 | Tecan Ag | |
GB8607975D0 (en) * | 1986-04-01 | 1986-05-08 | Fisons Plc | Devices |
GB2190195A (en) * | 1986-05-09 | 1987-11-11 | Cambridge Life Sciences | Microtitre plate reader |
US4861727A (en) * | 1986-09-08 | 1989-08-29 | C. R. Bard, Inc. | Luminescent oxygen sensor based on a lanthanide complex |
US4945060A (en) * | 1988-03-15 | 1990-07-31 | Akzo N. V. | Device for detecting microorganisms |
US5164796A (en) * | 1988-03-15 | 1992-11-17 | Akzo N.V. | Apparatus and method for detection of microorganisms |
US5268304A (en) * | 1988-10-13 | 1993-12-07 | The United States Of America As Represented By The Secretary Of The Navy | Method of determining the concentration of a chemical of interest in a solution |
JP2897027B2 (ja) * | 1988-10-27 | 1999-05-31 | スズキ株式会社 | 免疫学的凝集反応検出装置 |
CA1329263C (en) * | 1989-03-01 | 1994-05-03 | Mark Krichever | Bar code scanner |
JP2750605B2 (ja) * | 1989-05-17 | 1998-05-13 | スズキ株式会社 | 粒子凝集パターン判定方法 |
US5082628A (en) * | 1989-09-19 | 1992-01-21 | Park Pharmaceuticals, Inc. | Luminometer |
JPH087222B2 (ja) * | 1990-01-18 | 1996-01-29 | 持田製薬株式会社 | 自動分注希釈装置 |
FR2659142B1 (fr) * | 1990-03-02 | 1992-06-05 | Gespac Instr Sa | Automate analyseur pour le groupage sanguin. |
ATE132537T1 (de) * | 1990-03-29 | 1996-01-15 | Avl Photronics Corp | Verfahren und apparat zum nachweis biologischer aktivitäten in einer probe |
JPH0678978B2 (ja) * | 1990-05-25 | 1994-10-05 | スズキ株式会社 | 凝集パターン検出装置 |
DE4109118C2 (de) * | 1991-03-20 | 1995-04-06 | Lange Gmbh Dr Bruno | Verfahren zum automatischen Auswerten eines Probeninhaltsstoffes einer Wasserprobe |
DE4123817C2 (de) * | 1991-07-18 | 1994-06-09 | Berthold Lab Prof Dr | Strahlungsmeßgerät, insbesondere zur Messung der Lumineszenz |
US5290701A (en) * | 1991-08-28 | 1994-03-01 | Wilkins Judd R | Microbial detection system and process |
US5304492A (en) * | 1991-11-26 | 1994-04-19 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Spectrophotometer for chemical analyses of fluids |
EP0592624B1 (de) * | 1992-03-09 | 2001-09-19 | Accumed International Inc. | Diagnostische mikrobiologische testvorrichtung und verfahren |
US5302813A (en) * | 1992-04-02 | 1994-04-12 | Symbol Technologies, Inc. | Multi-bit digitizer |
US5401465A (en) * | 1992-05-05 | 1995-03-28 | Chiron Corporation | Luminometer with reduced sample crosstalk |
US5432061A (en) * | 1992-09-01 | 1995-07-11 | Becton Dickinson And Company | Method and apparatus for detecting microorganisms |
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1993
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1994
- 1994-08-09 AU AU70203/94A patent/AU679078B2/en not_active Ceased
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- 1994-08-29 JP JP6204039A patent/JPH0829116B2/ja not_active Expired - Lifetime
- 1994-11-18 US US08/341,825 patent/US5595708A/en not_active Expired - Lifetime
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AU679078B2 (en) | 1997-06-19 |
CA2130014C (en) | 2001-02-20 |
JPH07163394A (ja) | 1995-06-27 |
US5397709A (en) | 1995-03-14 |
JPH0829116B2 (ja) | 1996-03-27 |
AU7020394A (en) | 1995-03-09 |
DE69429310T2 (de) | 2002-07-18 |
CA2130014A1 (en) | 1995-02-28 |
US5595708A (en) | 1997-01-21 |
EP0640826B1 (de) | 2001-12-05 |
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