DE69428877D1 - Hemmung einer Fehlentwicklung der Ovarien, verspüteter Pubertät oder sexuellem Infantilismus - Google Patents

Hemmung einer Fehlentwicklung der Ovarien, verspüteter Pubertät oder sexuellem Infantilismus

Info

Publication number
DE69428877D1
DE69428877D1 DE69428877T DE69428877T DE69428877D1 DE 69428877 D1 DE69428877 D1 DE 69428877D1 DE 69428877 T DE69428877 T DE 69428877T DE 69428877 T DE69428877 T DE 69428877T DE 69428877 D1 DE69428877 D1 DE 69428877D1
Authority
DE
Germany
Prior art keywords
inhibiting ovarian
sexual infantilism
late puberty
infantilism
sexual
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69428877T
Other languages
English (en)
Other versions
DE69428877T2 (de
Inventor
Jeffrey Alan Dodge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Application granted granted Critical
Publication of DE69428877D1 publication Critical patent/DE69428877D1/de
Publication of DE69428877T2 publication Critical patent/DE69428877T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
DE69428877T 1993-12-21 1994-12-19 Hemmung einer Fehlentwicklung der Ovarien, verspüteter Pubertät oder sexuellem Infantilismus Expired - Fee Related DE69428877T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/170,946 US5451589A (en) 1993-12-21 1993-12-21 Methods of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism

Publications (2)

Publication Number Publication Date
DE69428877D1 true DE69428877D1 (de) 2001-12-06
DE69428877T2 DE69428877T2 (de) 2002-04-25

Family

ID=22621923

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69428877T Expired - Fee Related DE69428877T2 (de) 1993-12-21 1994-12-19 Hemmung einer Fehlentwicklung der Ovarien, verspüteter Pubertät oder sexuellem Infantilismus

Country Status (19)

Country Link
US (4) US5451589A (de)
EP (1) EP0662325B1 (de)
JP (1) JPH07215867A (de)
KR (1) KR950016733A (de)
CN (1) CN1107702A (de)
AT (1) ATE207748T1 (de)
AU (1) AU8153294A (de)
CA (1) CA2138500A1 (de)
CZ (1) CZ321694A3 (de)
DE (1) DE69428877T2 (de)
DK (1) DK0662325T3 (de)
ES (1) ES2162844T3 (de)
HU (1) HUT71228A (de)
IL (1) IL112049A0 (de)
NO (1) NO944917L (de)
PT (1) PT662325E (de)
RU (1) RU94045272A (de)
SI (1) SI0662325T1 (de)
ZA (1) ZA9410097B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE406909T1 (de) 1993-05-13 2008-09-15 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
US5856340A (en) * 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
DE19604231A1 (de) * 1996-01-29 1997-07-31 Schering Ag Pharmazeutisches Kombinationspräparat und seine Verwendung zur Behandlung von gynäkologischen Störungen
IL120266A (en) * 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
TW442286B (en) * 1996-02-28 2001-06-23 Pfizer New therapeutic uses of estrogen agonists
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
US6054446A (en) 1997-12-24 2000-04-25 Sri International Anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use
US6649645B1 (en) 1998-12-23 2003-11-18 Pharmacia Corporation Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
WO2000066612A1 (en) 1999-05-04 2000-11-09 Strakan Limited Androgen glycosides and androgenic activity thereof
US20040087572A1 (en) * 2000-10-25 2004-05-06 Anderson Pamela Wang Method for inhibiting cataracts

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US5075321A (en) * 1987-03-24 1991-12-24 University Of Pennsylvania Methods of treating diseases characterized by interactions of IgG-containing immune complexes with macrophage Fc receptors using antiestrogenic benzothiophenes
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体

Also Published As

Publication number Publication date
US5843962A (en) 1998-12-01
EP0662325A3 (de) 1995-10-11
CN1107702A (zh) 1995-09-06
KR950016733A (ko) 1995-07-20
ZA9410097B (en) 1996-06-19
IL112049A0 (en) 1995-03-15
ATE207748T1 (de) 2001-11-15
HU9403654D0 (en) 1995-02-28
DK0662325T3 (da) 2001-12-03
EP0662325A2 (de) 1995-07-12
DE69428877T2 (de) 2002-04-25
CA2138500A1 (en) 1995-06-22
US5719165A (en) 1998-02-17
PT662325E (pt) 2002-03-28
JPH07215867A (ja) 1995-08-15
CZ321694A3 (en) 1995-08-16
ES2162844T3 (es) 2002-01-16
NO944917D0 (no) 1994-12-19
HUT71228A (en) 1995-11-28
SI0662325T1 (en) 2002-06-30
AU8153294A (en) 1995-06-29
NO944917L (no) 1995-06-22
EP0662325B1 (de) 2001-10-31
US5760060A (en) 1998-06-02
US5451589A (en) 1995-09-19
RU94045272A (ru) 1996-10-20

Similar Documents

Publication Publication Date Title
UA26930C2 (uk) Засіб для іhгібуваhhя еhдометріозу
DE69430465T2 (de) Hemmung uteriner Fibrose
DK0659416T3 (da) Inhibering af seborE og acne
DE69412049D1 (de) Hemmung von dysfunctionalen Uterusblutungen
DE69428877T2 (de) Hemmung einer Fehlentwicklung der Ovarien, verspüteter Pubertät oder sexuellem Infantilismus

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee