DE69427185T2 - Phase-Stift Kolloide zur Verwendung als Ultraschallkontrastmittel - Google Patents
Phase-Stift Kolloide zur Verwendung als UltraschallkontrastmittelInfo
- Publication number
- DE69427185T2 DE69427185T2 DE69427185T DE69427185T DE69427185T2 DE 69427185 T2 DE69427185 T2 DE 69427185T2 DE 69427185 T DE69427185 T DE 69427185T DE 69427185 T DE69427185 T DE 69427185T DE 69427185 T2 DE69427185 T2 DE 69427185T2
- Authority
- DE
- Germany
- Prior art keywords
- liquid
- dispersed
- phase
- animal
- contrast agents
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000002961 echo contrast media Substances 0.000 title abstract 2
- 239000000084 colloidal system Substances 0.000 title 1
- 239000007788 liquid Substances 0.000 abstract 4
- 239000000839 emulsion Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000012071 phase Substances 0.000 abstract 2
- 230000036760 body temperature Effects 0.000 abstract 1
- 238000009835 boiling Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 238000001246 colloidal dispersion Methods 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000006260 foam Substances 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000001361 intraarterial administration Methods 0.000 abstract 1
- 238000007912 intraperitoneal administration Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 239000007791 liquid phase Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000004530 micro-emulsion Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 238000002604 ultrasonography Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/008,172 US5558855A (en) | 1993-01-25 | 1993-01-25 | Phase shift colloids as ultrasound contrast agents |
| US08/148,284 US5595723A (en) | 1993-01-25 | 1993-11-08 | Method for preparing storage stable colloids |
| PCT/US1994/000422 WO1994016739A1 (en) | 1993-01-25 | 1994-01-19 | Phase shift colloids as ultrasound contrast agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69427185D1 DE69427185D1 (de) | 2001-06-13 |
| DE69427185T2 true DE69427185T2 (de) | 2001-12-06 |
Family
ID=26677890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69427185T Expired - Fee Related DE69427185T2 (de) | 1993-01-25 | 1994-01-19 | Phase-Stift Kolloide zur Verwendung als Ultraschallkontrastmittel |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US5558853A (de) |
| EP (1) | EP0680341B1 (de) |
| JP (1) | JP3621413B2 (de) |
| CN (1) | CN1068230C (de) |
| AT (1) | ATE200985T1 (de) |
| BR (1) | BR9405667A (de) |
| CA (1) | CA2154590C (de) |
| CZ (1) | CZ191695A3 (de) |
| DE (1) | DE69427185T2 (de) |
| ES (1) | ES2158892T3 (de) |
| FI (1) | FI953546A (de) |
| HU (1) | HUT72323A (de) |
| NO (1) | NO952819L (de) |
| NZ (1) | NZ262237A (de) |
| PL (1) | PL176116B1 (de) |
| SG (1) | SG52198A1 (de) |
| SK (1) | SK281535B6 (de) |
| WO (1) | WO1994016739A1 (de) |
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1994
- 1994-01-19 NZ NZ262237A patent/NZ262237A/en unknown
- 1994-01-19 CA CA002154590A patent/CA2154590C/en not_active Expired - Fee Related
- 1994-01-19 CZ CZ951916A patent/CZ191695A3/cs unknown
- 1994-01-19 BR BR9405667A patent/BR9405667A/pt not_active Application Discontinuation
- 1994-01-19 JP JP51708494A patent/JP3621413B2/ja not_active Expired - Fee Related
- 1994-01-19 US US08/182,024 patent/US5558853A/en not_active Expired - Lifetime
- 1994-01-19 DE DE69427185T patent/DE69427185T2/de not_active Expired - Fee Related
- 1994-01-19 ES ES94908587T patent/ES2158892T3/es not_active Expired - Lifetime
- 1994-01-19 SG SG1995002382A patent/SG52198A1/en unknown
- 1994-01-19 AT AT94908587T patent/ATE200985T1/de active
- 1994-01-19 HU HU9502163A patent/HUT72323A/hu unknown
- 1994-01-19 PL PL94309986A patent/PL176116B1/pl unknown
- 1994-01-19 EP EP94908587A patent/EP0680341B1/de not_active Expired - Lifetime
- 1994-01-19 CN CN94191564A patent/CN1068230C/zh not_active Expired - Fee Related
- 1994-01-19 WO PCT/US1994/000422 patent/WO1994016739A1/en not_active Application Discontinuation
- 1994-01-19 SK SK930-95A patent/SK281535B6/sk unknown
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1995
- 1995-06-06 US US08/469,472 patent/US5707607A/en not_active Expired - Fee Related
- 1995-07-17 NO NO952819A patent/NO952819L/no not_active Application Discontinuation
- 1995-07-24 FI FI953546A patent/FI953546A/fi unknown
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1996
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Also Published As
| Publication number | Publication date |
|---|---|
| CZ191695A3 (en) | 1996-05-15 |
| WO1994016739A1 (en) | 1994-08-04 |
| DE69427185D1 (de) | 2001-06-13 |
| SK281535B6 (sk) | 2001-04-09 |
| EP0680341B1 (de) | 2001-05-09 |
| CA2154590C (en) | 2001-06-12 |
| FI953546A0 (fi) | 1995-07-24 |
| ES2158892T3 (es) | 2001-09-16 |
| JPH08508977A (ja) | 1996-09-24 |
| CA2154590A1 (en) | 1994-08-04 |
| NO952819D0 (no) | 1995-07-17 |
| SK93095A3 (en) | 1995-11-08 |
| EP0680341A1 (de) | 1995-11-08 |
| BR9405667A (pt) | 1995-11-21 |
| HU9502163D0 (en) | 1995-09-28 |
| NZ262237A (en) | 1997-06-24 |
| US5558853A (en) | 1996-09-24 |
| ATE200985T1 (de) | 2001-05-15 |
| SG52198A1 (en) | 1998-09-28 |
| CN1068230C (zh) | 2001-07-11 |
| JP3621413B2 (ja) | 2005-02-16 |
| US5707607A (en) | 1998-01-13 |
| NO952819L (no) | 1995-09-22 |
| PL176116B1 (pl) | 1999-04-30 |
| AU680652B2 (en) | 1997-08-07 |
| US5876696A (en) | 1999-03-02 |
| AU6162494A (en) | 1994-08-15 |
| PL309986A1 (en) | 1995-11-13 |
| HUT72323A (en) | 1996-04-29 |
| FI953546A (fi) | 1995-09-22 |
| CN1119831A (zh) | 1996-04-03 |
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