DE69426415T2 - Intrapulmonares hormonabgabesystem - Google Patents

Intrapulmonares hormonabgabesystem

Info

Publication number
DE69426415T2
DE69426415T2 DE69426415T DE69426415T DE69426415T2 DE 69426415 T2 DE69426415 T2 DE 69426415T2 DE 69426415 T DE69426415 T DE 69426415T DE 69426415 T DE69426415 T DE 69426415T DE 69426415 T2 DE69426415 T2 DE 69426415T2
Authority
DE
Germany
Prior art keywords
intrapulmonary
delivery system
hormone delivery
hormone
intrapulmonary hormone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69426415T
Other languages
English (en)
Other versions
DE69426415D1 (en
Inventor
M Rubsamen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aradigm Corp
Original Assignee
Aradigm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aradigm Corp filed Critical Aradigm Corp
Application granted granted Critical
Publication of DE69426415D1 publication Critical patent/DE69426415D1/de
Publication of DE69426415T2 publication Critical patent/DE69426415T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0083—Timers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/0081—Locking means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
DE69426415T 1993-01-29 1994-01-27 Intrapulmonares hormonabgabesystem Expired - Fee Related DE69426415T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1098993A 1993-01-29 1993-01-29
PCT/US1994/001072 WO1994016756A1 (en) 1993-01-29 1994-01-27 Intrapulmonary delivery of hormones

Publications (2)

Publication Number Publication Date
DE69426415D1 DE69426415D1 (en) 2001-01-18
DE69426415T2 true DE69426415T2 (de) 2001-07-26

Family

ID=21748377

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69426415T Expired - Fee Related DE69426415T2 (de) 1993-01-29 1994-01-27 Intrapulmonares hormonabgabesystem

Country Status (7)

Country Link
US (1) US5419315A (de)
EP (1) EP0681491B1 (de)
JP (1) JPH08509465A (de)
AU (1) AU6167894A (de)
DE (1) DE69426415T2 (de)
ES (1) ES2154673T3 (de)
WO (1) WO1994016756A1 (de)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6012450A (en) * 1993-01-29 2000-01-11 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US6024090A (en) * 1993-01-29 2000-02-15 Aradigm Corporation Method of treating a diabetic patient by aerosolized administration of insulin lispro
US7448375B2 (en) * 1993-01-29 2008-11-11 Aradigm Corporation Method of treating diabetes mellitus in a patient
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
TW402506B (en) 1993-06-24 2000-08-21 Astra Ab Therapeutic preparation for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
IS1796B (is) * 1993-06-24 2001-12-31 Ab Astra Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
WO1995024183A1 (en) 1994-03-07 1995-09-14 Inhale Therapeutic Systems Methods and compositions for pulmonary delivery of insulin
US6165976A (en) 1994-06-23 2000-12-26 Astra Aktiebolag Therapeutic preparation for inhalation
US5635159A (en) * 1994-08-26 1997-06-03 Abbott Laboratories Aerosol drug formulations containing polyglycolyzed glycerides
PL321094A1 (en) 1994-12-22 1997-11-24 Astra Ab Parathyroid hormone (pth) containing preparation administered by inhalation
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
JP4155594B2 (ja) 1994-12-22 2008-09-24 アストラゼネカ・アクチエボラーグ エアゾール製剤
US5758637A (en) 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US5809997A (en) * 1995-05-18 1998-09-22 Medtrac Technologies, Inc. Electronic medication chronolog device
US5635161A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Aerosol drug formulations containing vegetable oils
WO2004096328A1 (ja) * 1995-07-12 2004-11-11 Hiroyuki Yokoi ハンディ型吸入器
CA2392466C (en) 1995-12-07 2004-05-04 Jago Research Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
US5829435A (en) * 1997-02-24 1998-11-03 Aradigm Corporation Prefilter for prevention of clogging of a nozzle in the generation of an aerosol and prevention of administration of undesirable particles
US6197746B1 (en) 1998-05-19 2001-03-06 Repligen Corporation Method of using secretin for treating autism
DE69830185D1 (de) 1997-05-19 2005-06-16 Repligen Corp Verfahren zur unterstützung der differentialdiagnostik und behandlung von autistischen syndromen
NZ506289A (en) * 1998-03-16 2004-12-24 Nektar Therapeutics Aerosolized active agent delivery to the lungs at a flow rate of less than 17 liters per minute
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US6606992B1 (en) * 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US6540983B1 (en) * 2000-01-25 2003-04-01 Aeropharm Technology Incorporated Medical aerosol formulation
EP1267718A2 (de) 2000-04-03 2003-01-02 IEP Pharmaceutical Devices, Inc. Verfahren zum messen von veränderungen der luftwege in menschen und säugetire
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US8336545B2 (en) 2000-05-05 2012-12-25 Novartis Pharma Ag Methods and systems for operating an aerosol generator
US6543443B1 (en) * 2000-07-12 2003-04-08 Aerogen, Inc. Methods and devices for nebulizing fluids
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
WO2003057291A1 (en) 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
EP1474196B1 (de) 2002-01-15 2016-08-17 Novartis AG Verfahren und systeme zum bedienen eines aerosol-erzeugers
WO2003088961A1 (en) * 2002-04-19 2003-10-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders
AU2003256253A1 (en) 2002-05-20 2003-12-02 Aerogen, Inc. Aerosol for medical treatment and methods
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
WO2004037843A2 (en) * 2002-10-25 2004-05-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments
US20040105818A1 (en) 2002-11-26 2004-06-03 Alexza Molecular Delivery Corporation Diuretic aerosols and methods of making and using them
US7638138B2 (en) * 2003-02-21 2009-12-29 Translational Research, Ltd. Compositions for nasal administration of pharmaceuticals
KR100974482B1 (ko) 2003-03-27 2010-08-10 가부시키가이샤 바이오악티스 비강용 분말 약제 투약 장치
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
CA2564083C (en) * 2004-04-23 2014-02-04 Philip Morris Usa Inc. Aerosol generators and methods for producing aerosols
WO2006016530A1 (ja) * 2004-08-10 2006-02-16 Translational Research, Ltd. 速効性でかつ高い吸収性を可能とする経鼻投与用組成物
SG156680A1 (en) 2004-10-27 2009-11-26 Univ Florida Adrenocorticotropic hormone analogs and related methods
CN101208123B (zh) 2005-05-25 2012-09-19 亚罗擎公司 振动系统和方法
US8348853B2 (en) * 2006-02-06 2013-01-08 Deka Products Limited Partnership System, method and device for aiding in the diagnosis of respiratory dysfunction
ES2622493T3 (es) 2006-02-24 2017-07-06 Rigel Pharmaceuticals, Inc. Composiciones y métodos para la inhibición de la ruta de JAK
EP2037999B1 (de) 2006-07-07 2016-12-28 Proteus Digital Health, Inc. Intelligentes parenterales verabreichungssystem
US8337817B2 (en) 2006-12-26 2012-12-25 Shin Nippon Biomedical Laboratories, Ltd. Preparation for transnasal application
JP5243548B2 (ja) 2007-10-25 2013-07-24 プロテウス デジタル ヘルス， インコーポレイテッド 情報システムのための流体伝達ポート
PE20150621A1 (es) 2009-01-23 2015-05-07 Rigel Pharmaceuticals Inc Derivados de 2,4-diamino-pirimidina n2, n4-disustituidos como inhibidores de jak3
US9101539B2 (en) * 2009-05-15 2015-08-11 Shin Nippon Biomedical Laboratories, Ltd. Intranasal pharmaceutical compositions with improved pharmacokinetics
GB2472327B (en) * 2009-07-31 2013-03-13 Shin Nippon Biomedical Lab Ltd Intranasal granisetron and nasal applicator
AU2011210352A1 (en) 2010-01-26 2012-08-09 Radikal Therapeutics Inc. Compositions and methods for prevention and treatment of pulmonary hypertension
SG189763A1 (en) 2010-02-01 2013-05-31 Proteus Digital Health Inc Two-wrist data gathering system
JP5841951B2 (ja) 2010-02-01 2016-01-13 プロテウス デジタル ヘルス， インコーポレイテッド データ収集システム
CA2865504A1 (en) 2012-03-23 2013-09-26 Oxigene, Inc. Compositions and methods for inhibition of cathepsins
US10987048B2 (en) * 2014-08-13 2021-04-27 Elwha Llc Systems, methods, and devices to incentivize inhaler use
US10765817B2 (en) 2014-08-13 2020-09-08 Elwha, Llc Methods, systems, and devices related to delivery of alcohol with an inhaler
DK3212212T3 (da) 2014-10-31 2020-12-21 Univ Monash Pulverformulering
CN111603643B (zh) 2015-04-02 2023-05-23 希尔－罗姆服务私人有限公司 呼吸装置的压力控制
AU2016287372B2 (en) * 2015-06-30 2021-07-01 Koninklijke Philips N.V. Control device for a medical aerosol delivery device
CN108136144B (zh) 2015-07-20 2020-10-30 珍珠治疗公司 气雾剂输送系统
TWI664024B (zh) * 2016-07-27 2019-07-01 和淞科技股份有限公司 噴霧裝置
US11744967B2 (en) 2017-09-26 2023-09-05 Shin Nippon Biomedical Laboratories, Ltd. Intranasal delivery devices
WO2020092845A1 (en) 2018-11-01 2020-05-07 Rigel Pharmaceuticals, Inc. Method and composition embodiments for treating acute myeloid leukemia
WO2020243612A1 (en) 2019-05-29 2020-12-03 Rigel Pharmaceuticals, Inc. Method of preventing and treating thrombosis
WO2021026451A1 (en) 2019-08-08 2021-02-11 Rigel Pharmaceuticals, Inc. Compounds and method for treating cytokine release syndrome
BR112022001896A2 (pt) 2019-08-14 2022-06-21 Rigel Pharmaceuticals Inc Método para bloquear ou atenuar síndrome de liberação de citocinas
TW202346291A (zh) 2022-03-23 2023-12-01 美商雷傑製藥公司 作為ｉｒａｋ抑制劑的嘧啶—２—基—吡唑化合物

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4106503A (en) * 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
US4604847A (en) * 1983-09-14 1986-08-12 Moulding Jr Thomas S Medicine package, method of opening the package, and machine for performing the method
FI76929C (fi) * 1984-09-25 1989-01-10 Etelae Haemeen Keuhkovammayhdi Inhalationsdoseringsanordning, som aer avsedd foer nogrann dosering av disponerande laekemedel som ges aot andningssjuka i undersoekningsskedet och/eller laekemedel som ges som spray under behandlingen.
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4686231A (en) * 1985-12-12 1987-08-11 Smithkline Beckman Corporation Inhibition of 5-lipoxygenase products
NZ219021A (en) * 1986-01-27 1989-06-28 Gea Farmaceutisk Fabrik As Inhaler: medicine discharged intermittently during each inhalation
DE3636669C2 (de) * 1986-10-28 2001-08-16 Siemens Ag Anordnung zur Zufuhr von Aerosol zu den Luftwegen und/oder Lungen eines Patienten
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
GB8900267D0 (en) * 1989-01-06 1989-03-08 Riker Laboratories Inc Narcotic analgesic formulations and apparatus containing same
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator
GB9023282D0 (en) * 1990-10-25 1990-12-05 Riker Laboratories Inc Inhalation device
GB9023281D0 (en) * 1990-10-25 1990-12-05 Riker Laboratories Inc Inhaler
US5404871A (en) * 1991-03-05 1995-04-11 Aradigm Delivery of aerosol medications for inspiration
WO1992017231A1 (en) * 1991-03-28 1992-10-15 Innomed, Inc. Microelectronic inhaler having a counter and timer
US5167506A (en) * 1991-10-24 1992-12-01 Minnesota Mining And Manufacturing Company Inhalation device training system
US5333106A (en) * 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers

Also Published As

Publication number Publication date
JPH08509465A (ja) 1996-10-08
EP0681491A4 (de) 1996-03-06
ES2154673T3 (es) 2001-04-16
DE69426415D1 (en) 2001-01-18
WO1994016756A1 (en) 1994-08-04
AU6167894A (en) 1994-08-15
EP0681491B1 (de) 2000-12-13
US5419315A (en) 1995-05-30
EP0681491A1 (de) 1995-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KRAMER - BARSKE - SCHMIDTCHEN, 81245 MUENCHEN

8339 Ceased/non-payment of the annual fee