DE69422339T2 - Verfahren zur Nachweis von Marijuana in einer Haar Probe - Google Patents

Verfahren zur Nachweis von Marijuana in einer Haar Probe

Info

Publication number
DE69422339T2
DE69422339T2 DE69422339T DE69422339T DE69422339T2 DE 69422339 T2 DE69422339 T2 DE 69422339T2 DE 69422339 T DE69422339 T DE 69422339T DE 69422339 T DE69422339 T DE 69422339T DE 69422339 T2 DE69422339 T2 DE 69422339T2
Authority
DE
Germany
Prior art keywords
sample
marijuana
keratin
keratin structure
digest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69422339T
Other languages
English (en)
Other versions
DE69422339D1 (de
Inventor
Werner A Baumgartner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Psychemedics Corp
Original Assignee
Psychemedics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Psychemedics Corp filed Critical Psychemedics Corp
Publication of DE69422339D1 publication Critical patent/DE69422339D1/de
Application granted granted Critical
Publication of DE69422339T2 publication Critical patent/DE69422339T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/405Concentrating samples by adsorption or absorption
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/948Sedatives, e.g. cannabinoids, barbiturates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • G01N1/4044Concentrating samples by chemical techniques; Digestion; Chemical decomposition
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N2001/002Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/007Devices specially adapted for forensic samples, e.g. tamper-proofing, sample tracking
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701Details
    • G01N2333/4742Keratin; Cytokeratin
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/961Chemistry: molecular biology and microbiology including a step of forming, releasing, or exposing the antigen or forming the hapten-immunogenic carrier complex or the antigen per se
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/962Prevention or removal of interfering materials or reactants or other treatment to enhance results, e.g. determining or preventing nonspecific binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/963Methods of stopping an enzyme reaction or stabilizing the test materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/825Pretreatment for removal of interfering factors from sample
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/901Drugs of abuse, e.g. narcotics, amphetamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]
DE69422339T 1993-02-03 1994-02-01 Verfahren zur Nachweis von Marijuana in einer Haar Probe Expired - Lifetime DE69422339T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/012,724 US5466579A (en) 1987-12-28 1993-02-03 Hair analysis method
PCT/US1994/001137 WO1994018561A1 (en) 1993-02-03 1994-02-01 Hair analysis method

Publications (2)

Publication Number Publication Date
DE69422339D1 DE69422339D1 (de) 2000-02-03
DE69422339T2 true DE69422339T2 (de) 2000-08-24

Family

ID=21756393

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69422339T Expired - Lifetime DE69422339T2 (de) 1993-02-03 1994-02-01 Verfahren zur Nachweis von Marijuana in einer Haar Probe

Country Status (8)

Country Link
US (1) US5466579A (de)
EP (1) EP0634014B1 (de)
JP (1) JP3424828B2 (de)
AT (1) ATE188292T1 (de)
CA (1) CA2133560C (de)
DE (1) DE69422339T2 (de)
ES (1) ES2142936T3 (de)
WO (1) WO1994018561A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10123711A1 (de) * 2001-05-15 2003-02-27 Wolfgang Altmeyer Verfahren zur Bestimmung der Herkunft biologischer Materialien

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6022693A (en) * 1987-12-28 2000-02-08 Psychemedics Corporation Hair analysis method
FI101809B (fi) * 1996-06-11 1998-08-31 Valtion Teknillinen Menetelmä näytteen analysoimiseksi hiilihydraattimatriisista
US5981204A (en) * 1997-05-06 1999-11-09 Johnson; Ted Donald Method for forensically screening hair samples for the presence of cannabinoids
US5910419A (en) * 1997-05-06 1999-06-08 Johnson; Ted Donald Method for forensically screening hair samples for the presence of cannabinoids
WO1999041989A1 (en) 1998-02-23 1999-08-26 Monfort, Inc. Method and system for dehairing animals
US20040043500A1 (en) * 2002-08-27 2004-03-04 Rumps J Eric Wafer-scale microwave digestion apparatus and methods
DE10353746A1 (de) * 2003-11-17 2005-06-09 Basf Ag Verfahren zum Entfernen von Hornsubstanzen aus Häuten toter Tiere
US7465586B2 (en) 2004-11-03 2008-12-16 Labone, Inc. Oral detection test for cannabinoid use
US7629129B1 (en) * 2005-04-26 2009-12-08 The United States Of America As Represented By The Secretary Of The Army Hair follicle bulb as a biodosimeter
US8084215B2 (en) * 2008-04-29 2011-12-27 Psychemedics Corporation Non-proteolytic method for the determination of analytes in keratinized structures
PL2623987T3 (pl) * 2008-04-29 2016-07-29 Psychemedics Corp Analiza wieloanalitowa w fazie stałej
WO2014117089A1 (en) 2013-01-25 2014-07-31 Case Western Reserve University Compositions and methods for the treatment of pervasive development disorders
ITPI20130026A1 (it) * 2013-04-06 2014-10-07 Univ Pisa Metodo e dispositivo per analisi di droghe d'abuso su materiale cheratinico
EP3039432B1 (de) 2013-08-28 2019-10-09 Psychemedics Corporation Unversehrtheitsprüfung von haarproben
JP6598844B2 (ja) 2014-03-27 2019-10-30 バード・ロック・バイオ・インコーポレイテッド ヒトカンナビノイド1(cb1)受容体に結合する抗体
AU2016330471B2 (en) 2015-09-30 2022-09-29 Bird Rock Bio, Inc. Antibodies that bind human cannabinoid 1 (CB1) receptor
CN105651573B (zh) * 2016-01-05 2018-05-01 中国科学院华南植物园 一种植物叶表皮毛脱除方法
CN113341135A (zh) * 2018-07-30 2021-09-03 杭州莱和生物技术有限公司 一种荧光免疫检测毛发痕量毒品的试剂盒及其图像检测方法与系统
CN110231323A (zh) * 2019-07-04 2019-09-13 广州大陌检测技术有限公司 毛发提取液、制备方法和应用以及毒品检测方法
CN110987548A (zh) * 2019-10-11 2020-04-10 广州万孚生物技术股份有限公司 毛发中毒品检测方法、前处理试剂与试剂盒
CN112748240A (zh) * 2020-12-24 2021-05-04 南京北成光生物科技有限公司 一种用于检测毛发中毒品的试剂盒及其检测方法
CN115060562B (zh) * 2022-06-27 2023-05-05 上海凯创生物技术有限公司 一种毛发毒品痕量检测提取液及其制备、使用方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3785771A (en) * 1969-08-19 1974-01-15 Du Pont Method and apparatus for analyzing a liquid containing macromolecules that would interfere with the analysis
US4273867A (en) * 1979-04-05 1981-06-16 Mallinckrodt, Inc. Method and reagent for counteracting lipemic interference
US6949344B1 (en) * 1987-12-28 2005-09-27 Psychemical Corporation Hair analysis method
CA2004068C (en) * 1988-12-16 2001-06-19 Werner A. Baumgartner Hair analysis method
JP2837921B2 (ja) * 1990-05-22 1998-12-16 サイケメディクス コーポレイション 毛髪分析法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10123711A1 (de) * 2001-05-15 2003-02-27 Wolfgang Altmeyer Verfahren zur Bestimmung der Herkunft biologischer Materialien

Also Published As

Publication number Publication date
JP3424828B2 (ja) 2003-07-07
CA2133560C (en) 2002-01-15
EP0634014A1 (de) 1995-01-18
DE69422339D1 (de) 2000-02-03
WO1994018561A1 (en) 1994-08-18
EP0634014B1 (de) 1999-12-29
EP0634014A4 (de) 1996-02-07
CA2133560A1 (en) 1994-08-18
JPH07508099A (ja) 1995-09-07
ES2142936T3 (es) 2000-05-01
ATE188292T1 (de) 2000-01-15
US5466579A (en) 1995-11-14

Similar Documents

Publication Publication Date Title
DE69422339T2 (de) Verfahren zur Nachweis von Marijuana in einer Haar Probe
ATE212674T1 (de) Verfahren und analytisches system zur genauen schnellen und einfachen ausführung von fibrinogen-assays
ATE319855T1 (de) Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung
DE69607830D1 (de) Verfahren zur isothermer amplifikation von nukleinsäure molekülen
DE19681033D2 (de) Verfahren zur Quantifizierung von Tumorzellen in einer Körperflüssigkeit und dazu geeignete Testkits
DE69941044D1 (de) Methoden, Apparat und Computerprogramm zur quantitativen Bestimmung von Nukleinsäurensequenzen in Proben unter Verwendung von Standardkurven und Abschätzungen von Amplifikationsverhältnissen
ATE142020T1 (de) Verfahren zur haaranalyse
ATE85131T1 (de) Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch.
ATE261127T1 (de) Vorrichtung und verfahren zur bestimmung von proteindomänegrenzen
PT696642E (pt) Processo para a identificacao de pertuebacoes do sistema proteina c / proteina s
DE69114339T2 (de) Verfahren zur Identifizierung oder Bestimmung von Proteinen und Verwendungen dazu.
SE9403833D0 (sv) Analysförfarande och kit
ATE111533T1 (de) Verfahren zur bestimmung von nukleinsäuren.
ATE278964T1 (de) Verfahren zur proteinextraktion
EP0458594A3 (en) Analysis of hair
EP0990901A3 (de) Computergestützte Identifizierung von Paraproteinen
DE69632826D1 (de) Nukleinsaeure erkennung von hepatitis gb virus
CA2004068A1 (en) Hair analysis method
ATE360705T1 (de) Nachweis von peroxidasen
ATE377092T1 (de) Verfahren zur isolierung und charakterisierung potentieller funktionen ausgehend von einer biologischen probe, welche nukleinsäuren enthält
DE3879946D1 (de) Verfahren, reagenzgemisch und zusammensetzung zur bestimmung der anwesenheit von bakterien- oder somazellen in urin.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition