DE69420024D1 - Zelleinkapselungsvorrichtung - Google Patents
ZelleinkapselungsvorrichtungInfo
- Publication number
- DE69420024D1 DE69420024D1 DE69420024T DE69420024T DE69420024D1 DE 69420024 D1 DE69420024 D1 DE 69420024D1 DE 69420024 T DE69420024 T DE 69420024T DE 69420024 T DE69420024 T DE 69420024T DE 69420024 D1 DE69420024 D1 DE 69420024D1
- Authority
- DE
- Germany
- Prior art keywords
- permeable membrane
- core
- devices
- cells
- zone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0085—Brain, e.g. brain implants; Spinal cord
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10501193A | 1993-08-10 | 1993-08-10 | |
PCT/US1994/007190 WO1995004521A1 (en) | 1993-08-10 | 1994-06-24 | Cell encapsulating device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69420024D1 true DE69420024D1 (de) | 1999-09-16 |
DE69420024T2 DE69420024T2 (de) | 2000-02-24 |
Family
ID=22303587
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69420024T Expired - Lifetime DE69420024T2 (de) | 1993-08-10 | 1994-06-24 | Zelleinkapselungsvorrichtung |
DE69433970T Expired - Lifetime DE69433970T2 (de) | 1993-08-10 | 1994-06-24 | Zelleinkapselungsvorrichtung |
DE0938893T Pending DE938893T1 (de) | 1993-08-10 | 1994-06-24 | Zelleinkapselungsvorrichtung |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69433970T Expired - Lifetime DE69433970T2 (de) | 1993-08-10 | 1994-06-24 | Zelleinkapselungsvorrichtung |
DE0938893T Pending DE938893T1 (de) | 1993-08-10 | 1994-06-24 | Zelleinkapselungsvorrichtung |
Country Status (9)
Country | Link |
---|---|
US (2) | US5980889A (de) |
EP (2) | EP0663817B1 (de) |
AT (2) | ATE183078T1 (de) |
AU (1) | AU678843B2 (de) |
CA (1) | CA2147626C (de) |
DE (3) | DE69420024T2 (de) |
DK (1) | DK0663817T3 (de) |
ES (1) | ES2138665T3 (de) |
WO (1) | WO1995004521A1 (de) |
Families Citing this family (80)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE183078T1 (de) * | 1993-08-10 | 1999-08-15 | Gore & Ass | Zelleinkapselungsvorrichtung |
US6187757B1 (en) | 1995-06-07 | 2001-02-13 | Ariad Pharmaceuticals, Inc. | Regulation of biological events using novel compounds |
WO1997010807A1 (en) * | 1995-09-22 | 1997-03-27 | Gore Hybrid Technologies, Inc. | Improved cell encapsulation device |
US5855613A (en) | 1995-10-13 | 1999-01-05 | Islet Sheet Medical, Inc. | Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change |
US5952226A (en) * | 1996-11-05 | 1999-09-14 | Modex Therapeutiques | Hypoxia responsive EPO producing cells |
US6306491B1 (en) * | 1996-12-20 | 2001-10-23 | Gore Enterprise Holdings, Inc. | Respiratory aids |
US6368858B1 (en) * | 1997-07-22 | 2002-04-09 | The General Hospital Corporation | Modulation of multicellular aggregates by pressure from growth in a matrix |
US6287558B1 (en) * | 1997-08-01 | 2001-09-11 | Biohybrio Technologies Llc | Devices containing cells or tissue and an agent that inhibits damage by a host cell molecule |
US6984635B1 (en) | 1998-02-13 | 2006-01-10 | Board Of Trustees Of The Leland Stanford Jr. University | Dimerizing agents, their production and use |
US6303136B1 (en) * | 1998-04-13 | 2001-10-16 | Neurotech S.A. | Cells or tissue attached to a non-degradable filamentous matrix encapsulated by a semi-permeable membrane |
US20020095157A1 (en) | 1999-07-23 | 2002-07-18 | Bowman Steven M. | Graft fixation device combination |
US6179840B1 (en) | 1999-07-23 | 2001-01-30 | Ethicon, Inc. | Graft fixation device and method |
WO2001054593A1 (en) * | 2000-01-31 | 2001-08-02 | The General Hospital Corporation | Neural regeneration conduit |
US20020127265A1 (en) * | 2000-12-21 | 2002-09-12 | Bowman Steven M. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
CA2365376C (en) | 2000-12-21 | 2006-03-28 | Ethicon, Inc. | Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US6852330B2 (en) * | 2000-12-21 | 2005-02-08 | Depuy Mitek, Inc. | Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration |
US6599323B2 (en) * | 2000-12-21 | 2003-07-29 | Ethicon, Inc. | Reinforced tissue implants and methods of manufacture and use |
CZ298160B6 (cs) * | 2001-01-18 | 2007-07-11 | Prístroj pro vyvolání imunitní odezvy pri lécbe rakoviny | |
CA2447763A1 (en) * | 2001-06-08 | 2002-12-19 | Boehringer Ingelheim Pharmaceuticals, Inc. | Methods for improving cell line activity in immunoisolation devices |
ATE420654T1 (de) | 2001-08-15 | 2009-01-15 | Univ Brown Res Found | Behandlung von muskeldystrophien und verwandter erkrankungen |
AU2003216436A1 (en) | 2002-02-08 | 2003-09-02 | Life Technologies Corporation | Compositions and methods for restoring immune responsiveness in patients with immunological defects |
US20030170278A1 (en) * | 2002-03-11 | 2003-09-11 | Wolf David E. | Microreactor and method of determining a microreactor suitable for a predetermined mammal |
EP1539929B1 (de) | 2002-06-28 | 2013-04-10 | Life Technologies Corporation | Verfahren zur wiederherstellung des immunrepertoirs in patienten mit immunologischen defekten in verbindung mit autoimmunität sowie transplantation von organen oder hämatopoetischen stammzellen |
US20040078090A1 (en) | 2002-10-18 | 2004-04-22 | Francois Binette | Biocompatible scaffolds with tissue fragments |
US7824701B2 (en) | 2002-10-18 | 2010-11-02 | Ethicon, Inc. | Biocompatible scaffold for ligament or tendon repair |
WO2004075855A2 (en) | 2003-02-26 | 2004-09-10 | Biomed Solutions, Llc | Process for in vivo treatment of specific biological targets in bodily fluid |
US8197837B2 (en) | 2003-03-07 | 2012-06-12 | Depuy Mitek, Inc. | Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof |
MXPA05012080A (es) * | 2003-05-08 | 2006-02-22 | Xcyte Therapies Inc | Generacion y aislamiento de celulas t especificas al antigeno. |
US8226715B2 (en) | 2003-06-30 | 2012-07-24 | Depuy Mitek, Inc. | Scaffold for connective tissue repair |
US10583220B2 (en) | 2003-08-11 | 2020-03-10 | DePuy Synthes Products, Inc. | Method and apparatus for resurfacing an articular surface |
GB2407394A (en) | 2003-10-23 | 2005-04-27 | Dow Corning Ltd | Optical waveguide with two differently dimensioned waveguiding layers on substrate |
US7316822B2 (en) | 2003-11-26 | 2008-01-08 | Ethicon, Inc. | Conformable tissue repair implant capable of injection delivery |
US7901461B2 (en) | 2003-12-05 | 2011-03-08 | Ethicon, Inc. | Viable tissue repair implants and methods of use |
US11395865B2 (en) | 2004-02-09 | 2022-07-26 | DePuy Synthes Products, Inc. | Scaffolds with viable tissue |
US8137686B2 (en) | 2004-04-20 | 2012-03-20 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
US8221780B2 (en) | 2004-04-20 | 2012-07-17 | Depuy Mitek, Inc. | Nonwoven tissue scaffold |
US8657881B2 (en) | 2004-04-20 | 2014-02-25 | Depuy Mitek, Llc | Meniscal repair scaffold |
US20060257368A1 (en) * | 2005-05-03 | 2006-11-16 | Clemson University | Devices and methods for improved viability of cells |
US20090196854A1 (en) * | 2008-02-04 | 2009-08-06 | Kytos Biosystems S.A. | Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery |
US20100080784A1 (en) * | 2008-09-12 | 2010-04-01 | Torrey Pines Institute For Molecular Studies | Methods for treating cachexia and lymphopenia |
EP2389435B1 (de) | 2009-01-23 | 2015-11-04 | NsGene A/S | Verbesserte zelllinien und ihre verwendung für verkapselte zell-bio-abgabe |
US9475709B2 (en) | 2010-08-25 | 2016-10-25 | Lockheed Martin Corporation | Perforated graphene deionization or desalination |
DK2621403T3 (en) * | 2010-09-27 | 2015-06-15 | Nsgene As | An implantable cell device with supporting and radial diffusible structure |
WO2012092299A1 (en) | 2010-12-27 | 2012-07-05 | Brown University | Therapeutic and diagnostic methods involving biglycan and utrophin |
KR20140066218A (ko) * | 2011-09-06 | 2014-05-30 | 스템 셀 써지컬 엘엘씨 | 수술용 봉합재, 이를 제조하는 방법, 및 이를 사용하는 방법 |
US9644179B2 (en) | 2011-11-23 | 2017-05-09 | The Trustees Of The University Of Pennsylvania | Use of PDL1 expressing cells to convert T cells into regulatory T cells |
US10017852B2 (en) | 2016-04-14 | 2018-07-10 | Lockheed Martin Corporation | Method for treating graphene sheets for large-scale transfer using free-float method |
US10980919B2 (en) | 2016-04-14 | 2021-04-20 | Lockheed Martin Corporation | Methods for in vivo and in vitro use of graphene and other two-dimensional materials |
US9744617B2 (en) | 2014-01-31 | 2017-08-29 | Lockheed Martin Corporation | Methods for perforating multi-layer graphene through ion bombardment |
US9610546B2 (en) | 2014-03-12 | 2017-04-04 | Lockheed Martin Corporation | Separation membranes formed from perforated graphene and methods for use thereof |
US10653824B2 (en) | 2012-05-25 | 2020-05-19 | Lockheed Martin Corporation | Two-dimensional materials and uses thereof |
US9844757B2 (en) | 2014-03-12 | 2017-12-19 | Lockheed Martin Corporation | Separation membranes formed from perforated graphene and methods for use thereof |
US9834809B2 (en) | 2014-02-28 | 2017-12-05 | Lockheed Martin Corporation | Syringe for obtaining nano-sized materials for selective assays and related methods of use |
US10213746B2 (en) | 2016-04-14 | 2019-02-26 | Lockheed Martin Corporation | Selective interfacial mitigation of graphene defects |
US10203295B2 (en) | 2016-04-14 | 2019-02-12 | Lockheed Martin Corporation | Methods for in situ monitoring and control of defect formation or healing |
USD720469S1 (en) | 2013-03-07 | 2014-12-30 | Viacyte, Inc. | Cell encapsulation device |
TW201504140A (zh) | 2013-03-12 | 2015-02-01 | Lockheed Corp | 形成具有均勻孔尺寸之多孔石墨烯之方法 |
EP2971039B1 (de) | 2013-03-14 | 2020-01-01 | Immusoft Corporation | Verfahren zur in-vitro-speicher-b-zellen-differenzierung und -transduktion mit vsv-g-pseudotypisierten viralen vektoren |
US9572918B2 (en) | 2013-06-21 | 2017-02-21 | Lockheed Martin Corporation | Graphene-based filter for isolating a substance from blood |
EP3099645A4 (de) | 2014-01-31 | 2017-09-27 | Lockheed Martin Corporation | Verfahren zur formung von verbundstrukturen mit einem zweidimensionalen material unter verwendung einer porösen, nichtbeschädigenden trägerschicht |
WO2015116946A1 (en) | 2014-01-31 | 2015-08-06 | Lockheed Martin Corporation | Perforating two-dimensional materials using broad ion field |
EP3188823A4 (de) | 2014-09-02 | 2018-04-25 | Lockheed Martin Corporation | Hämodialyse- und hämofiltrationsmembranen basierend auf einem zweidimensionalen membranmaterial und verfahren zur verwendung davon |
KR102546296B1 (ko) | 2014-10-31 | 2023-06-21 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | 변형된 t 세포에서 유전자 발현의 변경 및 그의 용도 |
KR102583138B1 (ko) | 2014-10-31 | 2023-09-26 | 더 트러스티스 오브 더 유니버시티 오브 펜실베니아 | T 세포를 자극 및 증대시키는 조성물 및 방법 |
ES2929570T3 (es) | 2014-12-19 | 2022-11-30 | Immusoft Corp | Células B para administración in vivo de agentes terapéuticos |
US10828353B2 (en) | 2015-01-31 | 2020-11-10 | The Trustees Of The University Of Pennsylvania | Compositions and methods for T cell delivery of therapeutic molecules |
AU2016220324B2 (en) | 2015-02-16 | 2020-07-02 | The Trustees Of The University Of Pennsylvania | A fully-human T cell receptor specific for the 369-377 epitope derived from the HER2/Neu (ERBB2) receptor protein |
WO2017023376A1 (en) | 2015-08-05 | 2017-02-09 | Lockheed Martin Corporation | Perforatable sheets of graphene-based material |
AU2016303049A1 (en) | 2015-08-06 | 2018-03-01 | Lockheed Martin Corporation | Nanoparticle modification and perforation of graphene |
US11110197B2 (en) * | 2016-02-24 | 2021-09-07 | Georgia Tech Research Corporation | Surgical suture materials with porous sheaths for drug delivery |
WO2017180135A1 (en) | 2016-04-14 | 2017-10-19 | Lockheed Martin Corporation | Membranes with tunable selectivity |
WO2017180139A1 (en) | 2016-04-14 | 2017-10-19 | Lockheed Martin Corporation | Two-dimensional membrane structures having flow passages |
CN109790508A (zh) * | 2016-06-28 | 2019-05-21 | 国立研究开发法人农业·食品产业技术综合研究机构 | 细胞封入用设备及其用途 |
US11723558B2 (en) | 2016-11-03 | 2023-08-15 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Encapsulation device systems with oxygen sensors with or without exogenous oxygen delivery |
SG10202104564SA (en) | 2016-11-03 | 2021-06-29 | Univ Arizona | Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation |
US11707611B2 (en) | 2016-11-08 | 2023-07-25 | W. L. Gore & Associates, Inc. | Implantable apparatus for retention of biological moieties |
US11052230B2 (en) | 2016-11-08 | 2021-07-06 | W. L. Gore & Associates, Inc. | Implantable encapsulation devices |
CN115645621A (zh) | 2016-11-10 | 2023-01-31 | 韦尔赛特公司 | 含有pdx1胰腺内胚层细胞的细胞递送装置及其方法 |
JP2021515576A (ja) | 2018-03-16 | 2021-06-24 | イミュソフト コーポレーション | フォリスタチンを分泌するように遺伝子操作されたb細胞ならびにフォリスタチン関連疾患、状態、障害を処置するために、ならびに筋肉の成長および強度を増強するためにこれを使用する方法 |
AU2019346547A1 (en) * | 2018-09-24 | 2021-04-29 | Procyon Technologies Llc | Methods and systems for implantable medical devices and vascularization membranes |
Family Cites Families (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3993072A (en) * | 1974-08-28 | 1976-11-23 | Alza Corporation | Microporous drug delivery device |
CA1085104A (en) * | 1977-03-21 | 1980-09-09 | Anthony M. Sun | Artificial endocrine pancreas |
US4743545A (en) * | 1984-08-09 | 1988-05-10 | Torobin Leonard B | Hollow porous microspheres containing biocatalyst |
US4409331A (en) * | 1979-03-28 | 1983-10-11 | Damon Corporation | Preparation of substances with encapsulated cells |
US4391909A (en) * | 1979-03-28 | 1983-07-05 | Damon Corporation | Microcapsules containing viable tissue cells |
US4298002A (en) * | 1979-09-10 | 1981-11-03 | National Patent Development Corporation | Porous hydrophilic materials, chambers therefrom, and devices comprising such chambers and biologically active tissue and methods of preparation |
US4420589A (en) * | 1980-07-07 | 1983-12-13 | Stoy Vladimir A | Polymer composition including polyacrylonitrile polymers and process for preparing same |
US4353888A (en) * | 1980-12-23 | 1982-10-12 | Sefton Michael V | Encapsulation of live animal cells |
US4495288A (en) * | 1981-03-13 | 1985-01-22 | Damon Biotech, Inc. | Method of culturing anchorage dependent cells |
US4378016A (en) * | 1981-07-15 | 1983-03-29 | Biotek, Inc. | Artificial endocrine gland containing hormone-producing cells |
US4505266A (en) * | 1981-10-26 | 1985-03-19 | Massachusetts Institute Of Technology | Method of using a fibrous lattice |
EP0120061A4 (de) * | 1982-09-29 | 1986-08-21 | Theodore E Spielberg | Eingekapselte lebende genetisch programmierte organismen die arzneimittel erzeugen. |
CA1196862A (en) * | 1983-06-01 | 1985-11-19 | Anthony M.F. Sun | Microencapsulation of living tissue and cells |
US4806355A (en) * | 1983-06-06 | 1989-02-21 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
US4631188A (en) * | 1983-08-31 | 1986-12-23 | S.K.Y. Polymers, Ltd. (Kingston Technologies) | Injectable physiologically-acceptable polymeric composition |
US4803168A (en) * | 1983-09-01 | 1989-02-07 | Damon Biotech, Inc. | Microencapsulation with polymers |
EP0147939A2 (de) * | 1983-11-15 | 1985-07-10 | JOHNSON & JOHNSON | Einpflanzbarer Modul zur Regulierung der Glykämie |
US4663286A (en) * | 1984-02-13 | 1987-05-05 | Damon Biotech, Inc. | Encapsulation of materials |
US4686098A (en) * | 1984-05-14 | 1987-08-11 | Merck & Co., Inc. | Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo |
CA1215922A (en) * | 1984-05-25 | 1986-12-30 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
US4722898A (en) * | 1985-04-29 | 1988-02-02 | Minnesota Mining And Manufacturing Company | Immobilization of biological cells in polytetrafluoroethylene matrix |
AU589438B2 (en) * | 1985-08-26 | 1989-10-12 | Hana Biologics, Inc. | Transplantable artificial tissue and process |
US4902295A (en) * | 1985-08-26 | 1990-02-20 | Hana Biologics, Inc. | Transplantable artificial tissue |
US4997443A (en) * | 1985-08-26 | 1991-03-05 | Hana Biologics, Inc. | Transplantable artificial tissue and process |
US5030225A (en) * | 1987-03-13 | 1991-07-09 | Brown University Research Foundation | Electrically-charged nerve guidance channels |
US5218039A (en) * | 1987-04-28 | 1993-06-08 | Kingston Technologies, Inc. | Pan emulsion |
US4911717A (en) * | 1987-06-18 | 1990-03-27 | Gaskill Iii Harold V | Intravasular artificial organ |
US4942129A (en) * | 1987-07-28 | 1990-07-17 | Queen's University At Kingston | Multiple membrane microencapsulation |
US5182111A (en) * | 1987-11-17 | 1993-01-26 | Boston University Research Foundation | In vivo delivery of active factors by co-cultured cell implants |
US5418154A (en) * | 1987-11-17 | 1995-05-23 | Brown University Research Foundation | Method of preparing elongated seamless capsules containing biological material |
US5158881A (en) * | 1987-11-17 | 1992-10-27 | Brown University Research Foundation | Method and system for encapsulating cells in a tubular extrudate in separate cell compartments |
US4892538A (en) * | 1987-11-17 | 1990-01-09 | Brown University Research Foundation | In vivo delivery of neurotransmitters by implanted, encapsulated cells |
US5106627A (en) * | 1987-11-17 | 1992-04-21 | Brown University Research Foundation | Neurological therapy devices |
US5283187A (en) * | 1987-11-17 | 1994-02-01 | Brown University Research Foundation | Cell culture-containing tubular capsule produced by co-extrusion |
EP0331521A3 (de) * | 1988-03-04 | 1991-01-23 | Kingston Technologies, Inc. | Polyakrylonitrilmischung und Verfahren zu ihrer Herstellung |
US5081035A (en) * | 1988-04-18 | 1992-01-14 | The University Of Michigan | Bioreactor system |
US4941812A (en) * | 1988-05-10 | 1990-07-17 | E. I. Du Pont De Nemours And Company | Spinneret for production of a hollow filament within a hollow filament composite fiber having spacing means |
FR2634382B1 (fr) * | 1988-07-21 | 1990-10-26 | Applic Techn Photoniques | Pancreas artificiel |
AU4071789A (en) * | 1988-08-12 | 1990-03-05 | Cell Biotech, Inc. | Process for purification of islet cells; monoclonal antibodies directed to islet and acinar cells; and process for making and using same |
CA1323959C (en) * | 1988-09-16 | 1993-11-09 | Andreas F. Von Recum | Soft tissue implant with micron-scale surface texture to optimize anchorage |
US5011486A (en) * | 1988-11-18 | 1991-04-30 | Brown University Research Foundation | Composite nerve guidance channels |
US5017490A (en) * | 1989-03-10 | 1991-05-21 | Baxter International Inc. | Method for in vitro reproduction and growth of cells in culture medium |
EP0422209B1 (de) * | 1989-04-25 | 1995-03-15 | Children's Medical Center Corporation | Implantaten für grosse mengen von zellen auf polymerische matrizen |
JP2738881B2 (ja) * | 1989-06-21 | 1998-04-08 | ブラウン ユニバーシティ リサーチ ファウンデイション | 神経治療システム |
WO1991000119A1 (en) * | 1989-06-30 | 1991-01-10 | Baxter International Inc. | Implantable device |
US5116493A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with reseedable matrix |
US5002661A (en) * | 1989-08-25 | 1991-03-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device |
US5116494A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with temperature sensitive matrix |
US5100392A (en) * | 1989-12-08 | 1992-03-31 | Biosynthesis, Inc. | Implantable device for administration of drugs or other liquid solutions |
WO1991010470A1 (en) * | 1990-01-08 | 1991-07-25 | Brown University Research Foundation | Devices and methods for enhanced delivery of active factors |
US4969705A (en) * | 1990-01-19 | 1990-11-13 | Kingston Technologies, L.P. | Memory polymer multiple cavity fiber splicer |
US5084350A (en) * | 1990-02-16 | 1992-01-28 | The Royal Institution For The Advance Of Learning (Mcgill University) | Method for encapsulating biologically active material including cells |
US5256418A (en) * | 1990-04-06 | 1993-10-26 | Organogenesis, Inc. | Collagen constructs |
CA2070816A1 (en) * | 1990-10-31 | 1992-05-01 | James H. Brauker | Close vascularization implant material |
US5314471A (en) * | 1991-07-24 | 1994-05-24 | Baxter International Inc. | Tissue inplant systems and methods for sustaining viable high cell densities within a host |
US5344454A (en) * | 1991-07-24 | 1994-09-06 | Baxter International Inc. | Closed porous chambers for implanting tissue in a host |
DE4108772A1 (de) * | 1991-03-18 | 1992-09-24 | Inst Textil & Faserforschung | Implantierbares biohybrides organ |
DK0585368T3 (da) * | 1991-04-25 | 1998-03-16 | Univ Brown Res Found | Implanterbart biokompatibelt immunisolatorisk vehikel til afgivelse af udvalgte terapeutiske produkter |
US5453278A (en) * | 1991-07-24 | 1995-09-26 | Baxter International Inc. | Laminated barriers for tissue implants |
US5116753A (en) * | 1991-07-30 | 1992-05-26 | The Salk Institute For Biological Studies | Maintenance of pancreatic islets |
JP3524919B2 (ja) * | 1991-10-30 | 2004-05-10 | マサチューセッツ インスティテュート オブ テクノロジー | 臓器移植のための予備血管新生されたポリマー性移植片 |
ES2167332T3 (es) * | 1992-04-01 | 2002-05-16 | Baxter Int | Procedimiento y sistemas para el implante de celulas vivas en organismos huespedes. |
AU4114993A (en) * | 1992-04-24 | 1993-11-29 | Polymer Technology Group, Inc., The | Biocompatible, therapeutic, implantable device |
JPH07505786A (ja) * | 1992-04-24 | 1995-06-29 | ソマティクス セラピー コーポレイション | 生存可能な細胞の培養法および体液中の化合物濃度の調整法 |
DK0663951T3 (da) * | 1992-09-28 | 2002-09-30 | Univ Brown Res Found | Chitosan-matricer til indkapslede celler |
ATE183078T1 (de) * | 1993-08-10 | 1999-08-15 | Gore & Ass | Zelleinkapselungsvorrichtung |
DK0688196T3 (da) * | 1994-01-11 | 2002-06-03 | Baxter Int | Med åbninger forsynede implantatsystemer |
-
1994
- 1994-06-24 AT AT94922456T patent/ATE183078T1/de active
- 1994-06-24 AT AT98124882T patent/ATE274340T1/de not_active IP Right Cessation
- 1994-06-24 ES ES94922456T patent/ES2138665T3/es not_active Expired - Lifetime
- 1994-06-24 EP EP94922456A patent/EP0663817B1/de not_active Expired - Lifetime
- 1994-06-24 AU AU73563/94A patent/AU678843B2/en not_active Expired
- 1994-06-24 DE DE69420024T patent/DE69420024T2/de not_active Expired - Lifetime
- 1994-06-24 DE DE69433970T patent/DE69433970T2/de not_active Expired - Lifetime
- 1994-06-24 EP EP98124882A patent/EP0938893B1/de not_active Expired - Lifetime
- 1994-06-24 CA CA002147626A patent/CA2147626C/en not_active Expired - Lifetime
- 1994-06-24 DK DK94922456T patent/DK0663817T3/da active
- 1994-06-24 WO PCT/US1994/007190 patent/WO1995004521A1/en active IP Right Grant
- 1994-06-24 DE DE0938893T patent/DE938893T1/de active Pending
-
1997
- 1997-08-05 US US08/906,367 patent/US5980889A/en not_active Expired - Lifetime
-
1999
- 1999-11-08 US US09/435,510 patent/US6426214B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69420024T2 (de) | 2000-02-24 |
AU7356394A (en) | 1995-02-28 |
CA2147626A1 (en) | 1995-02-16 |
CA2147626C (en) | 1998-04-21 |
DE938893T1 (de) | 2000-03-09 |
DE69433970T2 (de) | 2005-08-11 |
ES2138665T3 (es) | 2000-01-16 |
US5980889A (en) | 1999-11-09 |
AU678843B2 (en) | 1997-06-12 |
EP0938893A1 (de) | 1999-09-01 |
US6426214B1 (en) | 2002-07-30 |
EP0938893B1 (de) | 2004-08-25 |
ATE183078T1 (de) | 1999-08-15 |
WO1995004521A1 (en) | 1995-02-16 |
DK0663817T3 (da) | 2000-03-13 |
ATE274340T1 (de) | 2004-09-15 |
EP0663817B1 (de) | 1999-08-11 |
DE69433970D1 (de) | 2004-09-30 |
EP0663817A1 (de) | 1995-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69420024D1 (de) | Zelleinkapselungsvorrichtung | |
SG48813A1 (en) | Improved composition and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules | |
AU2544201A (en) | Implantable device | |
KR960703343A (ko) | 밀봉주입식 박막 캡슐장치 및 그 제조방법(method and apparatus for sealing implantable, membrane encapsulation devices) | |
FI930883A (fi) | In vivo -dosering av aktiva faktorer med hjaelp av samodlade cellimplantat | |
DK463586A (da) | Fsh | |
ATE350068T1 (de) | Terminal-sterilisierte osteogene vorrichtungen und ihre herstellung | |
SE9504310D0 (sv) | Doseringsanordning | |
DK85786D0 (da) | Biologisk aktive fragmenter af human antihaemofilisk faktor og fremgangsmaade til fremstilling deraf | |
GR3030533T3 (en) | Process for cell capture and recovery | |
DE68906488T2 (de) | Verwendung von asymmetrischen membranen in abgabevorrichtungen. | |
WO1997044065A3 (en) | Device and method for encapsulated gene therapy | |
FI916066A0 (fi) | Neurologiskt vaordsystem. | |
CA2346644A1 (en) | Method for preventing xenograft transplant rejection using photodynamic therapy | |
PL298890A1 (en) | Sulfonylobenzyl substituted benzo- and pyridopyridones, method of obtaining sames and therapeutic agents containing them | |
ES2051135T3 (es) | Procedimiento y dispositivo para la fabricacion de una cadena de celulas solares. | |
ATE410054T1 (de) | Durch elektroporation vermittelter molekulartransfer in intakten pflanzen | |
NO975545L (no) | Cellelinje som produserer analgetiske forbindelser for behandling av smerte | |
FR2695828B1 (fr) | Dispositif de décontamination de déchets. | |
DK273490D0 (da) | Fremgangsmaade til udvinding af humant interleukin-4 fra bakterier | |
JO1488B1 (en) | Method for converting inorganic and organic waste into inert solids insoluble in water. | |
AU567940B2 (en) | Controlled release tablet | |
DE59604491D1 (de) | Polymerisierbare aromatische carbonsäuren und carbonsäureanhydride mit cyclischen carbonatgruppen sowie zubereitungen, enthaltend diese verbindungen | |
NO170936C (no) | Analogifremgangsmaate til fremstilling av terapeutisk aktive, substituerte vinylcefalosporiner | |
DE59909714D1 (de) | Calciumhaltige Brausetablette mit einem Antihistaminikum als Wirkstoff |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |