US5663180A
(en)
*
|
1983-10-29 |
1997-09-02 |
G.D. Searle & Co. |
Substituted cyclopentenes for the treatment of inflammation
|
US6492413B2
(en)
*
|
1993-01-15 |
2002-12-10 |
G.D. Searle & Co. |
3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
DK0679157T3
(da)
*
|
1993-01-15 |
1998-07-27 |
Searle & Co |
Nye 3,4-diarylthiophener og analoge deraf til anvendelse som antiinflammatoriske midler
|
GB9420616D0
(en)
*
|
1994-10-12 |
1994-11-30 |
Merck Sharp & Dohme |
Method, compositions and use
|
US6090834A
(en)
*
|
1993-05-21 |
2000-07-18 |
G.D. Searle & Co. |
Substituted oxazoles for the treatment of inflammation
|
US5840746A
(en)
*
|
1993-06-24 |
1998-11-24 |
Merck Frosst Canada, Inc. |
Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
|
US5474995A
(en)
*
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
GB9602877D0
(en)
*
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
EP0739340A1
(de)
*
|
1994-01-10 |
1996-10-30 |
Merck Frosst Canada Inc. |
Phenyl-heterocyclen als cox-2 inhibitoren
|
JPH10504542A
(ja)
*
|
1994-07-27 |
1998-05-06 |
ジー.ディー.サール アンド カンパニー |
炎症処置用の置換チアゾール化合物
|
US6613789B2
(en)
|
1994-07-28 |
2003-09-02 |
G. D. Searle & Co. |
Heterocyclo-substituted imidazoles for the treatment of inflammation
|
US6426360B1
(en)
*
|
1994-07-28 |
2002-07-30 |
G D Searle & Co. |
4,5-substituted imidazolyl compounds for the treatment of inflammation
|
US5620999A
(en)
*
|
1994-07-28 |
1997-04-15 |
Weier; Richard M. |
Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
|
US5616601A
(en)
*
|
1994-07-28 |
1997-04-01 |
Gd Searle & Co |
1,2-aryl and heteroaryl substituted imidazolyl compounds for the treatment of inflammation
|
US6239172B1
(en)
*
|
1997-04-10 |
2001-05-29 |
Nitrosystems, Inc. |
Formulations for treating disease and methods of using same
|
GB2294879A
(en)
*
|
1994-10-19 |
1996-05-15 |
Merck & Co Inc |
Cylcooxygenase-2 Inhibitors
|
EP0788476B1
(de)
*
|
1994-10-27 |
1999-10-20 |
Merck Frosst Canada & Co. |
Stilben-derivate verwendbar als cyclooxygenase-2 hemmer
|
JP2636819B2
(ja)
*
|
1994-12-20 |
1997-07-30 |
日本たばこ産業株式会社 |
オキサゾール系複素環式芳香族化合物
|
JPH10511089A
(ja)
*
|
1994-12-21 |
1998-10-27 |
メルク フロスト カナダ インコーポレーテツド |
Cox−2阻害剤としてのジアリール−2−(5h)−フラノン
|
US5633272A
(en)
*
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
CN1107058C
(zh)
*
|
1995-02-13 |
2003-04-30 |
G·D·瑟尔公司 |
用于治疗类症的取代的异噁唑
|
US5691374A
(en)
*
|
1995-05-18 |
1997-11-25 |
Merck Frosst Canada Inc. |
Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
|
US6515014B2
(en)
|
1995-06-02 |
2003-02-04 |
G. D. Searle & Co. |
Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US6512121B2
(en)
|
1998-09-14 |
2003-01-28 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
WO1996038418A1
(en)
|
1995-06-02 |
1996-12-05 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5643933A
(en)
*
|
1995-06-02 |
1997-07-01 |
G. D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US6156776A
(en)
*
|
1995-06-08 |
2000-12-05 |
Yu; Dingwei Tim |
Diaryl substituted thiazoles useful in the treatment of fungal infections
|
JPH11507669A
(ja)
|
1995-06-12 |
1999-07-06 |
ジー.ディー.サール アンド カンパニー |
シクロオキシゲナーゼ−2インヒビターとロイコトリエンb▲下4▼受容体アンタゴニストの組合せによる炎症と炎症関連疾患の治療
|
US5700816A
(en)
*
|
1995-06-12 |
1997-12-23 |
Isakson; Peter C. |
Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a leukotriene A4 hydrolase inhibitor
|
CA2224517A1
(en)
*
|
1995-06-12 |
1996-12-27 |
G.D. Searle & Co. |
Compositions comprising a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor
|
US6593361B2
(en)
|
1995-07-19 |
2003-07-15 |
Merck & Co Inc |
Method of treating colonic adenomas
|
US5968974A
(en)
*
|
1995-07-19 |
1999-10-19 |
Merck & Co., Inc. |
Method of treating colonic adenomas
|
US5837719A
(en)
*
|
1995-08-10 |
1998-11-17 |
Merck & Co., Inc. |
2,5-substituted aryl pyrroles, compositions containing such compounds and methods of use
|
US5792778A
(en)
*
|
1995-08-10 |
1998-08-11 |
Merck & Co., Inc. |
2-substituted aryl pyrroles, compositions containing such compounds and methods of use
|
US5786515A
(en)
*
|
1995-09-15 |
1998-07-28 |
Merck & Co., Inc. |
Synthesis of α-chloro or fluoro ketones
|
EP0853481A1
(de)
*
|
1995-09-27 |
1998-07-22 |
Merck Frosst Canada Inc. |
Zusammensetzungen zur behandlung von entzündungen, die gewisse prostaglandine und ein cyclooxygenase-2 hemmer enthalten
|
US6083949A
(en)
*
|
1995-10-06 |
2000-07-04 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
US5717100A
(en)
*
|
1995-10-06 |
1998-02-10 |
Merck & Co., Inc. |
Substituted imidazoles having anti-cancer and cytokine inhibitory activity
|
UA57002C2
(uk)
*
|
1995-10-13 |
2003-06-16 |
Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. |
Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування
|
US6020343A
(en)
*
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
US5981576A
(en)
*
|
1995-10-13 |
1999-11-09 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
AU716582B2
(en)
*
|
1995-10-17 |
2000-03-02 |
G.D. Searle & Co. |
Method of detecting cyclooxygenase-2
|
EP0904269B1
(de)
*
|
1995-10-30 |
2002-01-23 |
Merck Frosst Canada & Co. |
3,4-diaryl-2-hydroxy-2,5-dihydrofurane als wirkstoffvorstufen von cox-2 inhibitoren
|
US6222048B1
(en)
*
|
1995-12-18 |
2001-04-24 |
Merck Frosst Canada & Co. |
Diaryl-2-(5H)-furanones as Cox-2 inhibitors
|
ES2197983T3
(es)
*
|
1996-01-26 |
2004-01-16 |
G.D. SEARLE & CO. |
Imidazoles sustituidos con heterociclo para el tratamiento de la inflamacion.
|
US5733909A
(en)
*
|
1996-02-01 |
1998-03-31 |
Merck Frosst Canada, Inc. |
Diphenyl stilbenes as prodrugs to COX-2 inhibitors
|
ATE198323T1
(de)
*
|
1996-02-01 |
2001-01-15 |
Merck Frosst Canada Inc |
Diphenylstibene als prodrugs zu cox-2-inhibitoren
|
US5789413A
(en)
*
|
1996-02-01 |
1998-08-04 |
Merck Frosst Canada, Inc. |
Alkylated styrenes as prodrugs to COX-2 inhibitors
|
ES2147973T3
(es)
*
|
1996-02-01 |
2000-10-01 |
Merck Frosst Canada Inc |
Estirenos alquilatados como profarmacos de inhibidores de cox-2.
|
CA2246265A1
(en)
|
1996-02-13 |
1997-08-21 |
G.D. Searle & Co. |
Combinations having immunosuppressive effects, containing cyclooxygenase-2-inhibitors and 5-lipoxygenase inhibitors
|
DK0880363T3
(da)
|
1996-02-13 |
2003-01-20 |
Searle & Co |
Kombinationer der omfatter en cyclooxygenase-2 hæmmer samt en leukotrien A4 hydrolasehæmmer, som har immunsuppressive virkninger
|
EP0880362B1
(de)
*
|
1996-02-13 |
2005-05-25 |
G.D. SEARLE & CO. |
Zubereitungen, enthaltend einen cyclooxygenase-2-inhibitor und einen leukotrien-b4-rezeptor-antagonisten
|
JP3995716B2
(ja)
*
|
1996-03-18 |
2007-10-24 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
縮合環含有カルボン酸誘導体
|
EP0889878B1
(de)
*
|
1996-03-29 |
2002-09-04 |
Merck Frosst Canada & Co. |
Bisarylcyclobutenderivate als cyclooxygenasehemmer
|
US6180651B1
(en)
|
1996-04-04 |
2001-01-30 |
Bristol-Myers Squibb |
Diarylmethylidenefuran derivatives, processes for their preparation and their uses in therapeutics
|
US5807873A
(en)
*
|
1996-04-04 |
1998-09-15 |
Laboratories Upsa |
Diarylmethylidenefuran derivatives and their uses in therapeutics
|
FR2747123B1
(fr)
*
|
1996-04-04 |
1998-06-26 |
Union Pharma Scient Appl |
Nouveaux derives diarylmethylidene tetrahydrofurane, leurs procedes de preparation, et leurs utilisations en therapeutique
|
US5908858A
(en)
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
KR100387658B1
(ko)
*
|
1996-04-12 |
2003-08-19 |
지.디. 썰 엘엘씨 |
Cox-2저해제의프로드러그로서의치환된벤젠술폰아미드유도체
|
US5922742A
(en)
*
|
1996-04-23 |
1999-07-13 |
Merck Frosst Canada |
Pyridinyl-2-cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors
|
AU709609B2
(en)
*
|
1996-04-23 |
1999-09-02 |
Merck Frosst Canada & Co. |
Pyridinyl-2-cyclopenten-1-ones as selective cyclooxygenase-2 inhibitors
|
WO1997044027A1
(en)
*
|
1996-05-17 |
1997-11-27 |
Merck & Co., Inc. |
Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
|
IL126899A
(en)
*
|
1996-05-17 |
2004-03-28 |
Merck & Co Inc |
Preparations for once-daily treatment of diseases mediated by cyclooxygenase-2
|
AU775030B2
(en)
*
|
1996-05-17 |
2004-07-15 |
Merck Frosst Company |
Compositions for a once a day treatment of cyclooxygenase-2 mediated diseases
|
US5883267A
(en)
*
|
1996-05-31 |
1999-03-16 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as cox-2 inhibitors
|
HRP970289A2
(en)
*
|
1996-05-31 |
1998-04-30 |
Merck & Co Inc |
Process for preparing phenyl heterocycles useful as cox-2 inhibitors
|
US6677364B2
(en)
|
1998-04-20 |
2004-01-13 |
G.D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
ES2239357T3
(es)
*
|
1996-06-10 |
2005-09-16 |
MERCK & CO., INC. |
Imidazoles sustituidos que tienen actividad inhibidora de citoquinas.
|
GB9615867D0
(en)
*
|
1996-07-03 |
1996-09-11 |
Merck & Co Inc |
Process of preparing phenyl heterocycles useful as cox-2 inhibitors
|
US5677318A
(en)
*
|
1996-07-11 |
1997-10-14 |
Merck Frosst Canada, Inc. |
Diphenyl-1,2-3-thiadiazoles as anti-inflammatory agents
|
AP1055A
(en)
*
|
1996-08-14 |
2002-04-04 |
Searle & Co |
Crysttalline form of 4-[5-methyl-3-phenylisoxazol-4-YI] benzenesulfonamide.
|
US8022095B2
(en)
*
|
1996-08-16 |
2011-09-20 |
Pozen, Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US6586458B1
(en)
*
|
1996-08-16 |
2003-07-01 |
Pozen Inc. |
Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs
|
US5939069A
(en)
*
|
1996-08-23 |
1999-08-17 |
University Of Florida |
Materials and methods for detection and treatment of immune system dysfunctions
|
FR2753449B1
(fr)
*
|
1996-09-13 |
1998-12-04 |
Union Pharma Scient Appl |
Nouveaux derives 3,4-diaryloxazolone, leurs procedes de preparation, et leurs utilisations en therapeutique
|
IL128568A0
(en)
|
1996-10-15 |
2000-01-31 |
Searle & Co |
Use of cyclooxygenase-2 inhibitors for the manufacture of a medicament for the treatment and prevention of neoplasia
|
US5776954A
(en)
*
|
1996-10-30 |
1998-07-07 |
Merck & Co., Inc. |
Substituted pyridyl pyrroles, compositions containing such compounds and methods of use
|
US5985930A
(en)
|
1996-11-21 |
1999-11-16 |
Pasinetti; Giulio M. |
Treatment of neurodegenerative conditions with nimesulide
|
AU5377698A
(en)
*
|
1996-12-10 |
1998-07-03 |
G.D. Searle & Co. |
Substituted pyrrolyl compounds for the treatment of inflammation
|
EP0863134A1
(de)
*
|
1997-03-07 |
1998-09-09 |
Merck Frosst Canada Inc. |
2-(3,5-difluorophenyl)-3-(4-methylsulfonylphenyl)-2-cyclopenten-1-on zur Verwendung als Inhibitor der Cyclooxygenase-2
|
US6071954A
(en)
*
|
1997-03-14 |
2000-06-06 |
Merk Frosst Canada, Inc. |
(methylsulfonyl)phenyl-2-(5H)-furanones with oxygen link as COX-2 inhibitors
|
ATE244232T1
(de)
*
|
1997-03-14 |
2003-07-15 |
Merck Frosst Canada Inc |
(methylsulfonyl)phenyl-2-(5h)-furanone mit sauerstoff-bindung als cox-2-hemmer
|
US6004960A
(en)
*
|
1997-03-14 |
1999-12-21 |
Merck Frosst Canada, Inc. |
Pyridazinones as inhibitors of cyclooxygenase-2
|
ES2224366T3
(es)
*
|
1997-03-14 |
2005-03-01 |
MERCK FROSST CANADA & CO. |
Piridazinonas como inhibidores de ciclooxigenasa-2.
|
TW492959B
(en)
*
|
1997-04-18 |
2002-07-01 |
Merck & Co Inc |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors
|
US6130334A
(en)
*
|
1998-04-15 |
2000-10-10 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
US6127545A
(en)
*
|
1997-04-18 |
2000-10-03 |
Merck & Co., Inc. |
Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
|
US20040072889A1
(en)
*
|
1997-04-21 |
2004-04-15 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
|
US6525053B1
(en)
|
1997-08-22 |
2003-02-25 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
US6307047B1
(en)
*
|
1997-08-22 |
2001-10-23 |
Abbott Laboratories |
Prostaglandin endoperoxide H synthase biosynthesis inhibitors
|
ATE245649T1
(de)
|
1997-09-05 |
2003-08-15 |
Glaxo Group Ltd |
2,3-diaryl-pyrazolo(1,5-b)pyridazin derivate, deren herstellung und deren verwendung als cyclooxygenase 2 (cox-2) inhibitoren
|
EP1015431B1
(de)
*
|
1997-09-12 |
2005-04-20 |
Merck Frosst Canada & Co. |
2-aminopyridine als inhibitoren von cyclooxygenase-2
|
US6004950A
(en)
*
|
1997-09-12 |
1999-12-21 |
Merck Frosst Canada, Inc. |
2-aminopyridines as inhibitors of cyclooxygenase-2
|
RS49982B
(sr)
|
1997-09-17 |
2008-09-29 |
Euro-Celtique S.A., |
Sinergistička analgetička kombinacija analgetičkog opijata i inhibitora ciklooksigenaze-2
|
US6020339A
(en)
*
|
1997-10-03 |
2000-02-01 |
Merck & Co., Inc. |
Aryl furan derivatives as PDE IV inhibitors
|
US6034089A
(en)
*
|
1997-10-03 |
2000-03-07 |
Merck & Co., Inc. |
Aryl thiophene derivatives as PDE IV inhibitors
|
FR2769311B1
(fr)
*
|
1997-10-07 |
1999-12-24 |
Union Pharma Scient Appl |
Nouveaux derives 3,4-diarylthiazolin-2-one ou -2-thione, leurs procedes de preparation et leurs utilisations en therapeutique
|
US5972986A
(en)
*
|
1997-10-14 |
1999-10-26 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
|
US6080876A
(en)
*
|
1997-10-29 |
2000-06-27 |
Merck & Co., Inc. |
Process for making phenyl heterocycles useful as COX-2 inhibitors
|
AU741790B2
(en)
*
|
1997-10-30 |
2001-12-06 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2(5H)-furanones as selective cyclooxygenase-2 inhibitors
|
US6133292A
(en)
*
|
1997-10-30 |
2000-10-17 |
Merck Frosst Canada & Co. |
Diaryl-5-alkyl-5-methyl-2-(5H)-furanones as selective cyclooxygenase-2-inhibitors
|
EP1027048A2
(de)
*
|
1997-10-31 |
2000-08-16 |
G.D. Searle & Co. |
Selektive cyclooxygenase inhibitoren gegen frühzeitige wehen
|
US6025353A
(en)
*
|
1997-11-19 |
2000-02-15 |
G.D. Searle & Co. |
Method of using cyclooxygenase-2 inhibitors as anti-angiogenic agents
|
EP1039914A4
(de)
*
|
1997-12-17 |
2007-06-27 |
Cornell Res Foundation Inc |
Cyclooxygenase-2 hemmung
|
US7041694B1
(en)
|
1997-12-17 |
2006-05-09 |
Cornell Research Foundation, Inc. |
Cyclooxygenase-2 inhibition
|
US6375957B1
(en)
|
1997-12-22 |
2002-04-23 |
Euro-Celtique, S.A. |
Opioid agonist/opioid antagonist/acetaminophen combinations
|
DK1041987T3
(da)
|
1997-12-22 |
2006-08-21 |
Euro Celtique Sa |
Oral farmaceutisk doseringsform omfattende en kombination af en opioid-agonist og naltrexon
|
NZ333399A
(en)
*
|
1997-12-24 |
2000-05-26 |
Sankyo Co |
Cyclooxygenase-2 inhibitors (COX-2) for the prevention and treatment of tumors, cachexia and tumor-metastasis
|
FR2775477B1
(fr)
*
|
1998-02-27 |
2000-05-19 |
Union Pharma Scient Appl |
Nouveaux derives diarylmethylene heterocycliques, leurs procedes de preparation et leurs utilisations en therapeutique
|
US6136804A
(en)
*
|
1998-03-13 |
2000-10-24 |
Merck & Co., Inc. |
Combination therapy for treating, preventing, or reducing the risks associated with acute coronary ischemic syndrome and related conditions
|
US6727238B2
(en)
*
|
1998-06-11 |
2004-04-27 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
TNSN99111A1
(fr)
*
|
1998-06-11 |
2005-11-10 |
Pfizer |
Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
US6294558B1
(en)
|
1999-05-31 |
2001-09-25 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
WO2000012093A1
(en)
*
|
1998-08-31 |
2000-03-09 |
Merck & Co., Inc. |
Method of treating neurodegenerative diseases
|
DE19842833B4
(de)
|
1998-09-18 |
2005-04-14 |
Merckle Gmbh |
2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung
|
JP2002528435A
(ja)
*
|
1998-10-27 |
2002-09-03 |
メルク エンド カムパニー インコーポレーテッド |
メチルチオフェニルヒドロキシケトンの合成
|
ES2234324T3
(es)
*
|
1998-11-02 |
2005-06-16 |
MERCK & CO., INC. |
Combinaciones de un agonista 5ht1b/1d y un inhibidor selectivo de cox-2 para el tratamiento de la migraña.
|
CN1263755C
(zh)
|
1998-11-03 |
2006-07-12 |
葛兰素集团有限公司 |
作为选择性cox-2抑制剂的吡唑并吡啶衍生物
|
SA99191255B1
(ar)
*
|
1998-11-30 |
2006-11-25 |
جي دي سيرل اند كو |
مركبات سيليكوكسيب celecoxib
|
US20030013739A1
(en)
*
|
1998-12-23 |
2003-01-16 |
Pharmacia Corporation |
Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia
|
US20040122011A1
(en)
*
|
1998-12-23 |
2004-06-24 |
Pharmacia Corporation |
Method of using a COX-2 inhibitor and a TACE inhibitors as a combination therapy
|
US6649645B1
(en)
|
1998-12-23 |
2003-11-18 |
Pharmacia Corporation |
Combination therapy of radiation and a COX-2 inhibitor for treatment of neoplasia
|
US6155267A
(en)
*
|
1998-12-31 |
2000-12-05 |
Medtronic, Inc. |
Implantable medical device monitoring method and system regarding same
|
EP1146789B1
(de)
*
|
1999-01-27 |
2009-03-18 |
Cornell Research Foundation, Inc. |
Behandlung von mit her-2/neu-überexprimierung einhergehendem krebs
|
ATE261444T1
(de)
|
1999-02-27 |
2004-03-15 |
Glaxo Group Ltd |
Pyrazolopyridine
|
US6281217B2
(en)
|
1999-03-25 |
2001-08-28 |
Dingwei Tim Yu |
Class of piperazino substituted thiazoles
|
KR20010111584A
(ko)
|
1999-04-14 |
2001-12-19 |
서경배 |
시클로옥시게네이즈-2 저해제로서의4,5-디아릴-3(2h)-퓨라논 유도체
|
KR20010094161A
(ko)
*
|
2000-04-04 |
2001-10-31 |
서경배 |
2,2-디메틸-4,5-디아릴-3(2h)퓨라논의 유도체 및 이를함유하는 선택적인 시클로옥시게네이즈-2 저해제로서약제학적 조성물
|
CO5261541A1
(es)
*
|
1999-05-14 |
2003-03-31 |
Pfizer Prod Inc |
Terapia de combinacion para el tratamiento de la migrana
|
CO5190664A1
(es)
|
1999-06-30 |
2002-08-29 |
Pfizer Prod Inc |
Terapia de combinacion para el tratamiento de migrana administracion de un receptor 5ht, cafeina y un inhibidor de ciclooxigenasa-2
|
US6066667A
(en)
*
|
1999-08-17 |
2000-05-23 |
Ashbrook; Charles D. |
Substituted furanones, compositions and antiarthritic use
|
WO2001017996A1
(en)
*
|
1999-09-08 |
2001-03-15 |
Merck Frosst Canada & Co. |
1,2,3-thiadiazoles and their use as cox-2 inhibitors
|
US6376242B1
(en)
*
|
1999-09-21 |
2002-04-23 |
Emory University |
Methods and compositions for treating platelet-related disorders using MPL pathway inhibitory agents
|
DE69940922D1
(de)
*
|
1999-10-08 |
2009-07-09 |
Merial Sas |
Polymorphe Form B von 3-(Cyclopropylmethoxy)-4-i4-(methylsulfonyl)phenyl -5,5-dimethyl-5H-furan-2-on
|
EP1099695A1
(de)
|
1999-11-09 |
2001-05-16 |
Laboratoire Theramex S.A. |
5-Aryl-1H-1,2,4-triazolverbindungen als Cyclooxygenase-2 Inhibitoren und diese enthaltende pharmazeutische Zusammensetzungen
|
EP1104759B1
(de)
|
1999-12-03 |
2003-10-22 |
Pfizer Products Inc. |
Heteroarylphenylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel
|
EP1104760B1
(de)
|
1999-12-03 |
2003-03-12 |
Pfizer Products Inc. |
Sulfamoylheteroarylpyrazolverbindungen zur Verwendung als analgetisches/entzündungshemmendes Mittel
|
MXPA02005539A
(es)
|
1999-12-03 |
2002-09-02 |
Pfizer Prod Inc |
Derivados de heterociclo-alquilsulfonil-pirazol como agentes anti-inflamatorios/analgesicos.
|
DK1104758T3
(da)
|
1999-12-03 |
2003-10-20 |
Pfizer Prod Inc |
Acetylenderivativer som anti-inflammatoriske/analgesiske lægemidler
|
UA74539C2
(en)
|
1999-12-08 |
2006-01-16 |
Pharmacia Corp |
Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)
|
BR0008060A
(pt)
*
|
1999-12-08 |
2002-02-05 |
Pharmacia Corp |
Composições inibidoras de ciclooxigenase-2 tendo rápido inìcio de eficácia terapêutica
|
CN1216869C
(zh)
*
|
1999-12-08 |
2005-08-31 |
药品公司 |
赛利可喜的多态晶型
|
GB9930358D0
(en)
|
1999-12-22 |
2000-02-09 |
Glaxo Group Ltd |
Process for the preparation of chemical compounds
|
RU2002119574A
(ru)
*
|
1999-12-23 |
2004-01-10 |
Нитромед, Инк. (Us) |
Нитрозированные и нитрозилированные ингибиторы циклооксигеназы-2, композиции на их основе и способы их применения
|
DE10001166A1
(de)
|
2000-01-13 |
2001-07-19 |
Merckle Gmbh |
Anellierte Pyrrolverbindungen, diese enthaltende pharmazeutische Mittel und deren Verwendung
|
CA2398995C
(en)
|
2000-02-04 |
2014-09-23 |
Children's Hospital Research Foundation |
Lipid hydrolysis therapy for atherosclerosis and related diseases
|
DK1255547T3
(da)
|
2000-02-08 |
2008-12-01 |
Euro Celtique Sa |
Kontrolleret-frigivelsessammensætninger indeholdende opioid-agonist og antagonist
|
RS50407B
(sr)
|
2000-02-08 |
2009-12-31 |
Euro-Celtique S.A., |
Oralne formulacije opijatnog agonista otporne na mehaničke,termičke i/ili hemijske promene fizičkih osobina doznog oblika
|
US20020183362A1
(en)
*
|
2000-04-25 |
2002-12-05 |
Pharmacia Corporation |
2-Fluorobenzenesulfonyl compounds for the treatment of inflammation
|
ES2166710B1
(es)
*
|
2000-04-25 |
2004-10-16 |
J. URIACH & CIA, S.A. |
Nuevos compuestos heterociclicos con actividad antiinflamatoria.
|
US6686390B2
(en)
*
|
2000-05-22 |
2004-02-03 |
Dr. Reddy's Laboratories Limited |
Compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them
|
PT1296665E
(pt)
|
2000-06-13 |
2011-07-05 |
Wyeth Llc |
Composições analgésicas e anti-inflamatórias contendo celecoxib e ibuprofeno
|
US6465509B2
(en)
|
2000-06-30 |
2002-10-15 |
Merck Frosst Canada & Co. |
Pyrones as inhibitors of cyclooxygenase-2
|
PE20020146A1
(es)
*
|
2000-07-13 |
2002-03-31 |
Upjohn Co |
Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
|
CA2414674A1
(en)
*
|
2000-07-13 |
2002-01-24 |
Pharmacia Corporation |
Use of cox-2 inhibitors in the treatment and prevention of ocular cox-2 mediated disorders
|
JP2004510705A
(ja)
*
|
2000-07-20 |
2004-04-08 |
ラウラス エイエス |
方法
|
US6716829B2
(en)
|
2000-07-27 |
2004-04-06 |
Pharmacia Corporation |
Aldosterone antagonist and cyclooxygenase-2 inhibitor combination therapy to prevent or treat inflammation-related cardiovascular disorders
|
PE20020506A1
(es)
|
2000-08-22 |
2002-07-09 |
Glaxo Group Ltd |
Derivados de pirazol fusionados como inhibidores de la proteina cinasa
|
AU2001285334A1
(en)
*
|
2000-08-29 |
2002-03-13 |
Peter Van Patten |
Combination for the treatment of migraine comprising a cyclooxygenase-2 inhibitor and acetylsalicylic acid
|
GB0021494D0
(en)
*
|
2000-09-01 |
2000-10-18 |
Glaxo Group Ltd |
Chemical comkpounds
|
US20030219461A1
(en)
*
|
2000-09-12 |
2003-11-27 |
Britten Nancy J. |
Parenteral combination therapy for infective conditions
|
US20050004199A1
(en)
*
|
2000-09-18 |
2005-01-06 |
George Hartman |
Treatment of inflammation with a combination of a cyclooxygenase-2 inhibitor and an integrin alpha-v antagonist
|
DE10057366A1
(de)
*
|
2000-11-18 |
2002-05-23 |
Mahle Gmbh |
Verfahren zur gießtechnischen Herstellung eines Kolbens mit einem gekühlten Ringträger
|
AU2002239344A1
(en)
|
2000-12-15 |
2002-06-24 |
Glaxo Group Limited |
Pyrazolopyridines
|
US7163940B2
(en)
|
2000-12-15 |
2007-01-16 |
Smithkline Beecham Corporation |
Pyrazolopyridinyl pyrimidine therapeutic compounds
|
DE60122939T2
(de)
|
2000-12-21 |
2007-01-11 |
Nitromed, Inc., Bedford |
Substituierte arylverbindungen als neue, cyclooxygenase-2-selektive inhibitoren, zusammensetzungen und verwendungsverfahren
|
US7115565B2
(en)
*
|
2001-01-18 |
2006-10-03 |
Pharmacia & Upjohn Company |
Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
|
AUPR283801A0
(en)
*
|
2001-02-01 |
2001-03-01 |
Australian National University, The |
Chemical compounds and methods
|
US20050143360A1
(en)
*
|
2001-02-02 |
2005-06-30 |
Joel Krasnow |
Method of using a cyclooxygenase-2 inhibitor and sex steroids as a combination therapy for the treatment and prevention of dismenorrhea
|
DE10107683A1
(de)
|
2001-02-19 |
2002-08-29 |
Merckle Gmbh Chem Pharm Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
EP1366048B1
(de)
|
2001-03-08 |
2004-08-25 |
SmithKline Beecham Corporation |
Pyrazolopyridinderivate
|
WO2002078700A1
(en)
|
2001-03-30 |
2002-10-10 |
Smithkline Beecham Corporation |
Pyralopyridines, process for their preparation and use as therapteutic compounds
|
MY137736A
(en)
|
2001-04-03 |
2009-03-31 |
Pharmacia Corp |
Reconstitutable parenteral composition
|
DE60212949T2
(de)
|
2001-04-10 |
2007-01-04 |
Smithkline Beecham Corp. |
Antivirale pyrazolopyridin verbindungen
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
US6756498B2
(en)
|
2001-04-27 |
2004-06-29 |
Smithkline Beecham Corporation |
Process for the preparation of chemical compounds
|
ES2242028T3
(es)
|
2001-04-27 |
2005-11-01 |
Smithkline Beecham Corporation |
Derivados de pirazolo(1,5-a)piridina.
|
UA81224C2
(uk)
|
2001-05-02 |
2007-12-25 |
Euro Celtic S A |
Дозована форма оксикодону та її застосування
|
WO2002089798A2
(en)
*
|
2001-05-04 |
2002-11-14 |
Merck & Co., Inc. |
Method and compositions for treating migraines
|
ES2361148T3
(es)
|
2001-05-11 |
2011-06-14 |
Endo Pharmaceuticals Inc. |
Forma de dosificación de opioides de liberación controlada resistente al abuso.
|
GB0112802D0
(en)
*
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
GB0112810D0
(en)
*
|
2001-05-25 |
2001-07-18 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
US20030153801A1
(en)
*
|
2001-05-29 |
2003-08-14 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and radiation for inhibition or prevention of cardiovascular disease
|
CN1547474A
(zh)
*
|
2001-05-31 |
2004-11-17 |
|
含选择性环加氧酶-2抑制剂及一元醇的可渗透皮肤的组合物
|
US20060167074A1
(en)
*
|
2001-06-19 |
2006-07-27 |
Norbert Muller |
Methods and compositions for the treatment of psychiatric disorders
|
DE10129320A1
(de)
*
|
2001-06-19 |
2003-04-10 |
Norbert Mueller |
Verwendung von COX-2 Inhibitoren zur Behandlung von Schizophrenie, wahnhaften Störungen, affektiven Störungen oder Ticstörungen
|
CA2451008A1
(en)
|
2001-06-21 |
2003-01-03 |
Smithkline Beecham Corporation |
Imidazo[1,2-a!pyridine derivatives for the prophylaxis and treatment of herpes viral infections
|
ES2241964T3
(es)
|
2001-07-05 |
2005-11-01 |
Pfizer Products Inc. |
Heterocicloalquilsulfufonilpirazoles como agentes antiinflamatorios/abnalgesicos.
|
CA2454328C
(en)
|
2001-07-18 |
2008-03-18 |
Christopher D. Breder |
Pharmaceutical combinations of oxycodone and naloxone
|
WO2003013433A2
(en)
|
2001-08-06 |
2003-02-20 |
Euro-Celtique S.A. |
Sequestered antagonist formulations
|
UA80682C2
(en)
*
|
2001-08-06 |
2007-10-25 |
Pharmacia Corp |
Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
|
MXPA04001210A
(es)
|
2001-08-06 |
2004-07-08 |
Euro Celtique Sa |
Formulaciones de agonista opioide con antagonista liberable y aislado.
|
US20030068375A1
(en)
|
2001-08-06 |
2003-04-10 |
Curtis Wright |
Pharmaceutical formulation containing gelling agent
|
US20030044458A1
(en)
|
2001-08-06 |
2003-03-06 |
Curtis Wright |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
|
GB0119477D0
(en)
*
|
2001-08-09 |
2001-10-03 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
AR038957A1
(es)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
WO2003018575A1
(en)
*
|
2001-08-24 |
2003-03-06 |
Wyeth Holdings Corporation |
5-substituted-3(2h)-furanones useful for inhibition of farnesyl-protein transferase
|
US20030114483A1
(en)
*
|
2001-09-18 |
2003-06-19 |
Pharmacia Corporation |
Compositions of chromene cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
US20030236308A1
(en)
*
|
2001-09-18 |
2003-12-25 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and acetaminophen for treatment and prevention of inflammation, inflammation-mediated disorders and pain
|
JP2005506987A
(ja)
*
|
2001-09-26 |
2005-03-10 |
ファルマシア・コーポレーション |
感覚的に許容される口内崩壊性組成物
|
GT200200183A
(es)
|
2001-09-28 |
2003-05-23 |
|
Procedimiento para preparar derivados de heterocicloalquilsulfonil pirazol
|
EP1432712B1
(de)
|
2001-10-05 |
2006-05-17 |
SmithKline Beecham Corporation |
Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion
|
KR100810468B1
(ko)
|
2001-10-10 |
2008-03-07 |
씨제이제일제당 (주) |
사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난1h-인돌 유도체
|
KR100824233B1
(ko)
|
2001-10-10 |
2008-04-24 |
씨제이제일제당 (주) |
사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난3,4-디하이드로-1h-나프탈렌 유도체
|
WO2003037336A1
(en)
|
2001-11-02 |
2003-05-08 |
Pfizer Products Inc. |
1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile derivatives and other compounds as cyclooxygenase inhibitors for the treatment of arthritis, neurodegeneration and colon cancer
|
AU2002357043B2
(en)
|
2001-12-06 |
2008-04-24 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
FR2833164B1
(fr)
*
|
2001-12-07 |
2004-07-16 |
Oreal |
Compositions cosmetiques antisolaires a base d'un melange synergique de filtres et utilisations
|
EP1453830B1
(de)
|
2001-12-11 |
2007-09-12 |
SmithKline Beecham Corporation |
Pyrazolopyridin-derivate als antiherpesmittel
|
US20040082940A1
(en)
*
|
2002-10-22 |
2004-04-29 |
Michael Black |
Dermatological apparatus and method
|
DE10162120A1
(de)
*
|
2001-12-12 |
2003-06-18 |
Berolina Drug Dev Ab Svedala |
Deuterierte substituierte Dihydrofuranone sowie diese Verbindungen enthaltende Arzneimittel
|
US20030212138A1
(en)
*
|
2002-01-14 |
2003-11-13 |
Pharmacia Corporation |
Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor
|
US20030220374A1
(en)
*
|
2002-01-14 |
2003-11-27 |
Pharmacia Corporation |
Compositions and methods of treatment involving peroxisome proliferator-activated receptor-gamma agonists and cyclooxygenase-2 selective inhibitors
|
US6667330B2
(en)
|
2002-01-31 |
2003-12-23 |
Galileo Pharmaceuticals, Inc. |
Furanone derivatives
|
US7985771B2
(en)
*
|
2002-01-31 |
2011-07-26 |
Monsanto Technology Llc |
Furanone derivatives
|
CN102813654A
(zh)
|
2002-04-05 |
2012-12-12 |
欧洲凯尔蒂克公司 |
含有羟氢可待酮和烯丙羟吗啡酮的药物制剂
|
RU2004132721A
(ru)
*
|
2002-04-08 |
2005-06-27 |
Глэксо Груп Лимитед (GB) |
(2-алкокси)фенил)циклопент-1-енил)ароматическая карбо- и гетероциклическая карбоновая кислота и ее производные
|
IL164163A0
(en)
*
|
2002-04-09 |
2005-12-18 |
Pharmacia Corp |
Process for preparing a finely self-emulsifiable pharmaceutical composition
|
US7329401B2
(en)
|
2002-04-15 |
2008-02-12 |
The Regents Of The University Of California |
Cyclooxygenase-2 selective agents useful as imaging probes and related methods
|
AU2003230965B2
(en)
|
2002-04-17 |
2008-02-21 |
The Cleveland Clinic Foundation |
Systemic marker for monitoring anti-inflammatory and antioxidant actions of therapeutic agents
|
BR0309412A
(pt)
*
|
2002-04-22 |
2005-02-01 |
Pfizer Prod Inc |
Indol-2-onas como inibidores seletivos da ciclooxigenase-2
|
GB0210121D0
(en)
|
2002-05-02 |
2002-06-12 |
Celltech R&D Ltd |
Biological products
|
HUE039881T2
(hu)
|
2002-05-09 |
2019-02-28 |
Brigham & Womens Hospital Inc |
1L1RL-1, mint egy kardiovaszkuláris betegség-marker
|
WO2003095623A2
(en)
*
|
2002-05-10 |
2003-11-20 |
The Trustees Of Columbia University In The City Of New York |
Genetically engineered cell lines and systems for propagating varicella zoster virus and methods of use thereof
|
KR100804827B1
(ko)
*
|
2002-05-17 |
2008-02-20 |
씨제이제일제당 (주) |
티아졸리딘-4-온 유도체, 그 제조방법 및 약제학적 조성물
|
US20030225054A1
(en)
*
|
2002-06-03 |
2003-12-04 |
Jingwu Duan |
Combined use of tace inhibitors and COX2 inhibitors as anti-inflammatory agents
|
KR100465455B1
(ko)
|
2002-06-24 |
2005-01-13 |
씨제이 주식회사 |
2-티옥소티아졸 유도체, 그 제조방법 및 약제학적 조성물
|
KR100478467B1
(ko)
|
2002-06-24 |
2005-03-23 |
씨제이 주식회사 |
피라졸-3-온 유도체, 그 제조방법 및 약제학적 조성물
|
AU2003247622A1
(en)
*
|
2002-06-27 |
2004-01-19 |
Nitromed, Inc. |
Cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
US7211598B2
(en)
*
|
2002-06-28 |
2007-05-01 |
Nitromed, Inc. |
Oxime and/or hydrozone containing nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
|
BR0312402A
(pt)
*
|
2002-07-02 |
2005-04-26 |
Pharmacia Corp |
Utilização de inibidores seletivos de ciclooxigenase-2 e agentes trombolìticos para o tratamento ou prevenção de um episódio vaso-oclusivo
|
KR100467668B1
(ko)
*
|
2002-08-07 |
2005-01-24 |
씨제이 주식회사 |
1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
|
ES2263058T3
(es)
*
|
2002-08-19 |
2006-12-01 |
Glaxo Group Limited |
Derivados de pirimidina como inhibidores selectivos de cox-2.
|
DE10238045A1
(de)
|
2002-08-20 |
2004-03-04 |
Merckle Gmbh Chem.-Pharm. Fabrik |
2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
|
UY27939A1
(es)
|
2002-08-21 |
2004-03-31 |
Glaxo Group Ltd |
Compuestos
|
GB0221443D0
(en)
|
2002-09-16 |
2002-10-23 |
Glaxo Group Ltd |
Pyridine derivates
|
PT1551372T
(pt)
|
2002-09-20 |
2018-07-23 |
Alpharma Pharmaceuticals Llc |
Subunidade de sequestração e composições e métodos relacionados
|
US8303511B2
(en)
*
|
2002-09-26 |
2012-11-06 |
Pacesetter, Inc. |
Implantable pressure transducer system optimized for reduced thrombosis effect
|
JP2006504728A
(ja)
|
2002-10-03 |
2006-02-09 |
スミスクライン ビーチャム コーポレーション |
ピラソロピリジン誘導体系治療用化合物
|
DE60335957D1
(de)
*
|
2002-10-08 |
2011-03-17 |
Rinat Neuroscience Corp |
Verfahren zur behandlung von postoperativen schmerzen durch verabreichung eines antikörpers gegen nervenwachstumsfaktor und diesen enthaltende zusammensetzungen
|
WO2005000194A2
(en)
|
2002-10-08 |
2005-01-06 |
Rinat Neuroscience Corp. |
Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same
|
KR100484525B1
(ko)
*
|
2002-10-15 |
2005-04-20 |
씨제이 주식회사 |
이소티아졸 유도체, 그 제조방법 및 약제학적 조성물
|
US20040082543A1
(en)
*
|
2002-10-29 |
2004-04-29 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and NMDA receptor antagonists for the treatment or prevention of neuropathic pain
|
DE60336576D1
(de)
*
|
2002-10-30 |
2011-05-12 |
Merck Sharp & Dohme |
Hemmer der akt aktivität
|
GB0225548D0
(en)
*
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
AU2003283096A1
(en)
*
|
2002-11-05 |
2004-06-07 |
Merck Frosst Canada And Co. |
Nitric oxide releasing prodrugs of diaryl-2-(5h)-furanones as cyclooxygenase-2 inhibitors
|
WO2004043358A2
(en)
*
|
2002-11-08 |
2004-05-27 |
Bristol-Myers Squibb Company |
Formulations of low solubility bioactive agents and processes for making the same
|
US20040147581A1
(en)
*
|
2002-11-18 |
2004-07-29 |
Pharmacia Corporation |
Method of using a Cox-2 inhibitor and a 5-HT1A receptor modulator as a combination therapy
|
KR100470075B1
(ko)
|
2002-11-21 |
2005-02-05 |
씨제이 주식회사 |
1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
|
GB0227443D0
(en)
*
|
2002-11-25 |
2002-12-31 |
Glaxo Group Ltd |
Pyrimidine derivatives
|
KR100491317B1
(ko)
|
2002-11-26 |
2005-05-24 |
씨제이 주식회사 |
1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
|
KR100470076B1
(ko)
|
2002-11-27 |
2005-02-05 |
씨제이 주식회사 |
1,2,4-트리아졸 유도체, 그 제조방법 및 약제학적 조성물
|
JP2006511606A
(ja)
|
2002-12-13 |
2006-04-06 |
ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー |
下部尿路症状を治療するα−2−δリガンド
|
JP2006512367A
(ja)
*
|
2002-12-19 |
2006-04-13 |
ファルマシア・コーポレーション |
シクロオキシゲナーゼ−2選択阻害剤又はシクロオキシゲナーゼ−2阻害剤を抗ウイルス剤と組み合わせて使用する、ヘルペス・ウイルス感染症の治療の方法及び組成物
|
AU2003300264A1
(en)
*
|
2002-12-20 |
2004-07-22 |
Pharmacia Corporation |
Compositions of cyclooxygenase-2 selective inhibitors and selective serotonin reuptake inhibitors for the treatment or prevention of a vaso-occlusive event
|
ES2215474B1
(es)
*
|
2002-12-24 |
2005-12-16 |
J. URIACH & CIA S.A. |
Nuevos derivados de fosforamida.
|
US9498530B2
(en)
|
2002-12-24 |
2016-11-22 |
Rinat Neuroscience Corp. |
Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same
|
US7569364B2
(en)
*
|
2002-12-24 |
2009-08-04 |
Pfizer Inc. |
Anti-NGF antibodies and methods using same
|
CA2921578C
(en)
*
|
2002-12-24 |
2017-02-14 |
Rinat Neuroscience Corp. |
Anti-ngf antibodies and methods using same
|
WO2004060355A1
(en)
*
|
2002-12-26 |
2004-07-22 |
Pozen Inc. |
Multilayer Dosage Forms Containing NSAIDs and Triptans
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
US20070265606A1
(en)
*
|
2003-02-14 |
2007-11-15 |
Reliant Technologies, Inc. |
Method and Apparatus for Fractional Light-based Treatment of Obstructive Sleep Apnea
|
BRPI0407375A
(pt)
|
2003-02-19 |
2006-02-07 |
Rinat Neuroscience Corp |
Métodos para tratar dor por meio da administração de um antagonista do fator de crescimento neural e u nsaid e composições contendo os mesmos
|
US20050004098A1
(en)
*
|
2003-03-20 |
2005-01-06 |
Britten Nancy Jean |
Dispersible formulation of an anti-inflammatory agent
|
US20050009931A1
(en)
*
|
2003-03-20 |
2005-01-13 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
US20040214753A1
(en)
*
|
2003-03-20 |
2004-10-28 |
Britten Nancy Jean |
Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
|
CN1761487A
(zh)
*
|
2003-03-20 |
2006-04-19 |
法玛西雅公司 |
抗炎剂的可分散制剂
|
US20040220155A1
(en)
*
|
2003-03-28 |
2004-11-04 |
Pharmacia Corporation |
Method of providing a steroid-sparing benefit with a cyclooxygenase-2 inhibitor and compositions therewith
|
MY135852A
(en)
|
2003-04-21 |
2008-07-31 |
Euro Celtique Sa |
Pharmaceutical products
|
US20050159403A1
(en)
*
|
2003-04-22 |
2005-07-21 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of central nervous system damage
|
US20040229803A1
(en)
*
|
2003-04-22 |
2004-11-18 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a potassium ion channel modulator for the treatment of pain, inflammation or inflammation mediated disorders
|
US20060135506A1
(en)
*
|
2003-04-22 |
2006-06-22 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a calcium modulating agent for the treatment of pain, inflammation or inflammation mediated disorders
|
WO2004093814A2
(en)
*
|
2003-04-22 |
2004-11-04 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a sodium channel blocker
|
WO2004100895A2
(en)
*
|
2003-05-13 |
2004-11-25 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a peroxisome proliferator activated receptor agonist for the treatment of ischemic mediated central nervous system disorders
|
WO2004105699A2
(en)
*
|
2003-05-28 |
2004-12-09 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and a cannabinoid agent for the treatment of central nervous system damage
|
CA2753318A1
(en)
|
2003-05-30 |
2004-12-09 |
Ranbaxy Laboratories Limited |
Substituted pyrrole derivatives
|
CN1309717C
(zh)
*
|
2003-06-03 |
2007-04-11 |
李小虎 |
4-芳基-5h-噻吩-2-酮衍生物、其制法和用途
|
BRPI0410807A
(pt)
*
|
2003-06-06 |
2006-06-27 |
Glaxo Group Ltd |
composição farmacêutica, e, método pata tratar um mamìfero sofrendo de ou susceptìvel a condições associadas com dor cefálica
|
WO2005000238A2
(en)
*
|
2003-06-20 |
2005-01-06 |
Merck & Co., Inc. |
Use of selective cyclooxygenase-2 inhibitors for the treatment of endometriosis
|
US20050065154A1
(en)
*
|
2003-06-24 |
2005-03-24 |
Pharmacia Corporation |
Treatment of migraine accompanied by nausea with a combination of cyclooxygenase-2 selective inhibitors and anti-nausea agents
|
US20050101597A1
(en)
*
|
2003-07-10 |
2005-05-12 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitior and a non-NMDA glutamate modulator for the treatment of central nervous system damage
|
US20050014729A1
(en)
*
|
2003-07-16 |
2005-01-20 |
Pharmacia Corporation |
Method for the treatment or prevention of dermatological disorders with a cyclooxygenase-2 inhibitor alone and in combination with a dermatological treatment agent and compositions therewith
|
US20050075341A1
(en)
*
|
2003-07-17 |
2005-04-07 |
Pharmacia Corporation |
Compositions of a cyclooxygenase-2 selective inhibitor and an IKK inhibitor for the treatment of ischemic mediated central nervous system disorders or injury
|
JP2007502831A
(ja)
*
|
2003-08-20 |
2007-02-15 |
ニトロメッド インコーポレーティッド |
ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法
|
US20050119262A1
(en)
*
|
2003-08-21 |
2005-06-02 |
Pharmacia Corporation |
Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
|
US20050107350A1
(en)
*
|
2003-08-22 |
2005-05-19 |
Pharmacia Corporation |
Method for the treatment or prevention of bone disorders with a cyclooxygenase-2 inhibitor alone and in combination with a bone disorder treatment agent and compositions therewith
|
AU2004270161A1
(en)
*
|
2003-08-28 |
2005-03-17 |
Nicox S.A. |
Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
|
US20050187278A1
(en)
*
|
2003-08-28 |
2005-08-25 |
Pharmacia Corporation |
Treatment or prevention of vascular disorders with Cox-2 inhibitors in combination with cyclic AMP-specific phosphodiesterase inhibitors
|
EP2384753B1
(de)
|
2003-08-29 |
2016-01-06 |
The Brigham and Women's Hospital, Inc. |
Zellnekrosehemmer
|
US20050113409A1
(en)
*
|
2003-09-03 |
2005-05-26 |
Pharmacia Corporation |
Method for the prevention or treatment of pain, inflammation and inflammation-related disorders with a Cox-2 selective inhibitor in combination with a nitric oxide-donating agent and compositions therewith
|
US20050131028A1
(en)
*
|
2003-09-11 |
2005-06-16 |
Pharmacia Corporation |
Methods and compositions for the extended duration treatment of pain, inflammation and inflammation-related disorders
|
SI1663229T1
(sl)
|
2003-09-25 |
2010-08-31 |
Euro Celtique Sa |
Farmacevtske kombinacije hidrokodona in naltreksona
|
GB0323584D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Compounds
|
GB0323585D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Compounds
|
GB0323581D0
(en)
*
|
2003-10-08 |
2003-11-12 |
Glaxo Group Ltd |
Novel compounds
|
FR2860792B1
(fr)
*
|
2003-10-10 |
2006-02-24 |
Sanofi Synthelabo |
Derives de thiophene-2-carboxamide, leur preparation et leur application en therapeutique
|
WO2005044227A1
(en)
*
|
2003-11-05 |
2005-05-19 |
Glenmark Pharmaceuticals Limited |
Topical pharmaceutical compositions
|
US20050100594A1
(en)
*
|
2003-11-12 |
2005-05-12 |
Nilendu Sen |
Pharmaceutical formulation containing muscle relaxant and COX-II inhibitor
|
US7671072B2
(en)
*
|
2003-11-26 |
2010-03-02 |
Pfizer Inc. |
Aminopyrazole derivatives as GSK-3 inhibitors
|
US7067159B2
(en)
*
|
2003-12-05 |
2006-06-27 |
New Chapter, Inc. |
Methods for treating prostate cancer with herbal compositions
|
US7070816B2
(en)
*
|
2003-12-05 |
2006-07-04 |
New Chapter, Inc. |
Methods for treating prostatic intraepithelial neoplasia with herbal compositions
|
ES2381551T3
(es)
|
2003-12-05 |
2012-05-29 |
The Cleveland Clinic Foundation |
Marcadores de riesgo para enfermedad cardiovascular
|
CA2554716A1
(en)
*
|
2004-01-22 |
2005-08-04 |
Nitromed, Inc. |
Nitrosated and/or nitrosylated compounds, compositions and methods of use
|
BRPI0506994A
(pt)
|
2004-01-22 |
2007-07-03 |
Pfizer |
derivados de triazol que inibem a atividade antagonista da vasopressina
|
US7521473B2
(en)
*
|
2004-02-25 |
2009-04-21 |
Wyeth |
Inhibitors of protein tyrosine phosphatase 1B
|
WO2005081960A2
(en)
*
|
2004-02-25 |
2005-09-09 |
Wyeth |
Inhibitors of protein tyrosine phosphatase 1b
|
HUE037549T2
(hu)
*
|
2004-04-07 |
2018-09-28 |
Rinat Neuroscience Corp |
Eljárások csontrákfájdalom kezelésére idegi növekedési faktor antagonista antitest beadásával
|
BRPI0510340A
(pt)
*
|
2004-04-28 |
2007-10-30 |
Pfizer |
derivados de 3-heterociclil-4-feniltriazol como inibidores do receptor via da vasopressina
|
GB0410121D0
(en)
*
|
2004-05-06 |
2004-06-09 |
Glaxo Group Ltd |
Compounds
|
US7507823B2
(en)
*
|
2004-05-06 |
2009-03-24 |
Bristol-Myers Squibb Company |
Process of making aripiprazole particles
|
US20080138282A1
(en)
*
|
2004-06-03 |
2008-06-12 |
The Trustees Of Columbia University In The City Of New York |
Radiolabeled Arylsulfonyl Compounds and Uses Thereof
|
EP1604666A1
(de)
|
2004-06-08 |
2005-12-14 |
Euro-Celtique S.A. |
Opioide zur Behandlung der chronischen obstruktiven Lungenkrankheit
|
EP1765292B1
(de)
|
2004-06-12 |
2017-10-04 |
Collegium Pharmaceutical, Inc. |
Gegen missbrauch gesicherte arzneimittelformulierungen
|
KR20070039885A
(ko)
|
2004-07-01 |
2007-04-13 |
머크 앤드 캄파니 인코포레이티드 |
유사분열 키네신 억제제
|
ES2257929B1
(es)
*
|
2004-07-16 |
2007-05-01 |
Laboratorios Del Dr. Esteve, S.A. |
Derivados de pirazolina, procedimiento para su obtencion y utilizacion de los mismos como agentes terapeuticos.
|
AU2005266088A1
(en)
*
|
2004-07-22 |
2006-02-02 |
Pharmacia Corporation |
Compositions for treatment of inflammation and pain using a combination of a COX-2 selective inhibitor and a LTB4 receptor antagonist
|
EP1784179A4
(de)
|
2004-08-24 |
2010-03-31 |
Merck Sharp & Dohme |
Kombinationstherapie zur behandlung von cyclooxygenase-2-vermittelten krankheiten oder zuständen bei patienten mit risiko auf thrombotische kardiovaskuläre ereignisse
|
US7622142B2
(en)
*
|
2004-09-14 |
2009-11-24 |
New Chapter Inc. |
Methods for treating glioblastoma with herbal compositions
|
US20060064133A1
(en)
*
|
2004-09-17 |
2006-03-23 |
Cardiac Pacemakers, Inc. |
System and method for deriving relative physiologic measurements using an external computing device
|
WO2006041855A2
(en)
|
2004-10-04 |
2006-04-20 |
Nitromed, Inc. |
Compositions and methods using apocynin compounds and nitric oxide donors
|
CA2624601C
(en)
|
2004-10-06 |
2018-07-03 |
The Brigham And Women's Hospital, Inc. |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
AU2005304770A1
(en)
*
|
2004-11-08 |
2006-05-18 |
Nicox S.A. |
Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
|
US20080275093A1
(en)
*
|
2004-11-15 |
2008-11-06 |
Nitromed, Inc. |
Diuretic Compounds Comprising Heterocyclic Nitric Oxide Donor Groups, Compositions and Methods of Use
|
WO2006066968A1
(en)
|
2004-12-23 |
2006-06-29 |
Glaxo Group Limited |
Pyridine compounds for the treatment of prostaglandin mediated diseases
|
RU2401125C2
(ru)
|
2004-12-27 |
2010-10-10 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Способ стабилизации лекарственного средства против деменции
|
JP2008528507A
(ja)
*
|
2005-01-21 |
2008-07-31 |
ニトロメッド インコーポレーティッド |
複素環式の酸化窒素供与体基を含む心血管化合物、組成物および使用方法
|
SG175477A1
(en)
*
|
2005-01-31 |
2011-11-28 |
Mylan Lab Inc |
Hydroxylated nebivolol metabolites
|
US20090042819A1
(en)
*
|
2005-02-16 |
2009-02-12 |
Nitromed, Inc. |
Organic nitric oxide donor salts of antimicrobial compounds, compositions and methods of use
|
US7521435B2
(en)
*
|
2005-02-18 |
2009-04-21 |
Pharma Diagnostics, N.V. |
Silicon containing compounds having selective COX-2 inhibitory activity and methods of making and using the same
|
EP1702558A1
(de)
|
2005-02-28 |
2006-09-20 |
Euro-Celtique S.A. |
Verfahren und Vorrichtung zur Darmtätigkeitserfassung
|
AU2006218766A1
(en)
*
|
2005-02-28 |
2006-09-08 |
Nicox S.A. |
Cardiovascular compounds comprising nitric oxide enhancing groups, compositions and methods of use
|
JP2008533031A
(ja)
*
|
2005-03-09 |
2008-08-21 |
ニトロメッド インコーポレーティッド |
アンギオテンシンiiアンタゴニストの有機酸化窒素増強塩、組成物および使用法
|
WO2006110918A1
(en)
*
|
2005-04-13 |
2006-10-19 |
Ambit Biosciences Corporation |
Pyrrole compounds and uses thereof
|
JP5597343B2
(ja)
*
|
2005-04-28 |
2014-10-01 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
抗痴呆薬を含有する組成物
|
AU2006244393B2
(en)
*
|
2005-05-05 |
2012-06-21 |
Cook Biotech Incorporated |
Implantable materials and methods for inhibiting tissue adhesion formation
|
ES2382814T3
(es)
|
2005-05-17 |
2012-06-13 |
Merck Sharp & Dohme Ltd. |
Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
|
CA2608718A1
(en)
*
|
2005-05-18 |
2006-11-23 |
Pfizer Limited |
1, 2, 4-triazole derivatives as vasopressin antagonists
|
US20090048219A1
(en)
*
|
2005-05-23 |
2009-02-19 |
Nitromed Inc. |
Organic nitric oxide donor salts of nonsteroidal antiinflammatory compounds, compositions and methods of use
|
KR101310037B1
(ko)
|
2005-05-31 |
2013-09-24 |
밀란 인크. |
네비볼롤을 함유하는 조성물
|
WO2007016677A2
(en)
|
2005-08-02 |
2007-02-08 |
Nitromed, Inc. |
Nitric oxide enhancing antimicrobial compounds, compositions and methods of use
|
PE20070427A1
(es)
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Compuestos derivados de benzimidazoles sustituidos como inhibidores de tirosina quinasas
|
AU2006299383A1
(en)
*
|
2005-10-04 |
2007-04-12 |
Nitromed, Inc. |
Methods for treating respiratory disorders
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
EP1948599A1
(de)
|
2005-11-08 |
2008-07-30 |
Ranbaxy Laboratories Limited |
Verfahren zur herstellung von (3r,5r)-7-[2-(4-fluorphenyl)-5-isopropyl-3-phenyl-4-[(4-hydroxymethylphenylamino)carbonyl]pyrrol-1-yl]-3,5-dihydroxyheptansäure-hemicalciumsalz
|
EP1954685A4
(de)
*
|
2005-11-16 |
2009-11-11 |
Nitromed Inc |
Furoxanverbindungen, zusammensetzungen und anwendungsverfahren
|
TW200735866A
(en)
|
2005-11-18 |
2007-10-01 |
Synta Pharmaceuticals Corp |
Compounds for the treatment of proliferative disorders
|
EP1968584A2
(de)
*
|
2005-12-20 |
2008-09-17 |
Nitromed, Inc. |
Stickoxid-verstärkende glutaminsäure-verbindungen, zusammensetzungen und anwendungsverfahren
|
WO2007075542A2
(en)
*
|
2005-12-22 |
2007-07-05 |
Nitromed, Inc. |
Nitric oxide enhancing pyruvate compounds, compositions and methods of use
|
US20090062302A1
(en)
|
2006-01-24 |
2009-03-05 |
Buser-Doepner Carolyn A |
Jak2 Tyrosine Kinase Inhibition
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
PL2001496T3
(pl)
|
2006-03-15 |
2017-10-31 |
Brigham & Womens Hospital Inc |
Zastosowanie gelsoliny do diagnozowania i leczenia chorób zapalnych
|
AU2007243765A1
(en)
*
|
2006-03-29 |
2007-11-08 |
Nicox S.A. |
Nitric oxide enhancing prostaglandin compounds, compositions and methods of use
|
EA018917B1
(ru)
|
2006-04-19 |
2013-11-29 |
Новартис Аг |
6-о-замещенные бензоксазолы и бензотиазолы и способы подавления передачи сигналов от csf-1r
|
WO2007146229A2
(en)
|
2006-06-07 |
2007-12-21 |
Tethys Bioscience, Inc. |
Markers associated with arteriovascular events and methods of use thereof
|
EP2526932B1
(de)
|
2006-06-19 |
2017-06-07 |
Alpharma Pharmaceuticals LLC |
Pharmazeutische Zusammensetzung
|
US8128460B2
(en)
*
|
2006-09-14 |
2012-03-06 |
The Material Works, Ltd. |
Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
|
CA2770486C
(en)
|
2006-09-22 |
2014-07-15 |
Merck Sharp & Dohme Corp. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
US20080208179A1
(en)
*
|
2006-10-26 |
2008-08-28 |
Reliant Technologies, Inc. |
Methods of increasing skin permeability by treatment with electromagnetic radiation
|
US8513329B2
(en)
|
2006-10-31 |
2013-08-20 |
Bio-Tec Environmental, Llc |
Chemical additives to make polymeric materials biodegradable
|
WO2008055240A1
(en)
|
2006-10-31 |
2008-05-08 |
Bio-Tec Environmental, Llc |
Chemical additives to make polymeric materials biodegradable
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
BRPI0720351A2
(pt)
|
2006-12-22 |
2019-05-14 |
Recordati Ireland Limited |
terapia de combinação para distúrbios do trato urinário inferior com ligantes a2o e aines.
|
PL2109608T3
(pl)
|
2007-01-10 |
2011-08-31 |
Msd Italia Srl |
Indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy)-(PARP)
|
JP2010516679A
(ja)
*
|
2007-01-19 |
2010-05-20 |
マリンクロット インコーポレイテッド |
診断用および治療用シクロオキシゲナーゼ−2結合リガンド
|
US8822497B2
(en)
|
2007-03-01 |
2014-09-02 |
Novartis Ag |
PIM kinase inhibitors and methods of their use
|
GB0704407D0
(en)
|
2007-03-07 |
2007-04-18 |
Glaxo Group Ltd |
Compounds
|
EP2147315B1
(de)
|
2007-04-18 |
2013-06-26 |
Tethys Bioscience, Inc. |
Biomarker in verbindung mit diabetes und verwendungsverfahren dafür
|
WO2008144062A1
(en)
|
2007-05-21 |
2008-11-27 |
Novartis Ag |
Csf-1r inhibitors, compositions, and methods of use
|
JP5501227B2
(ja)
|
2007-06-27 |
2014-05-21 |
メルク・シャープ・アンド・ドーム・コーポレーション |
ヒストンデアセチラーゼ阻害剤としての4−カルボキシベンジルアミノ誘導体
|
US8247423B2
(en)
|
2007-07-12 |
2012-08-21 |
Tragara Pharmaceuticals, Inc. |
Methods and compositions for the treatment of cancer, tumors, and tumor-related disorders
|
US7943658B2
(en)
*
|
2007-07-23 |
2011-05-17 |
Bristol-Myers Squibb Company |
Indole indane amide compounds useful as CB2 agonists and method
|
JP5411141B2
(ja)
|
2007-09-10 |
2014-02-12 |
カルシメディカ,インク. |
細胞内カルシウムを調節する化合物
|
US8623418B2
(en)
|
2007-12-17 |
2014-01-07 |
Alpharma Pharmaceuticals Llc |
Pharmaceutical composition
|
JP2011515343A
(ja)
|
2008-03-03 |
2011-05-19 |
タイガー ファーマテック |
チロシンキナーゼ阻害薬
|
GB2460915B
(en)
|
2008-06-16 |
2011-05-25 |
Biovascular Inc |
Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor
|
GB0813142D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
GB0813144D0
(en)
|
2008-07-17 |
2008-08-27 |
Glaxo Group Ltd |
Novel compounds
|
WO2010027875A2
(en)
|
2008-08-27 |
2010-03-11 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
EP2177215A1
(de)
|
2008-10-17 |
2010-04-21 |
Laboratorios Del. Dr. Esteve, S.A. |
Co-Kristalle von Tramadol und NSARs
|
CN101429181A
(zh)
*
|
2008-12-18 |
2009-05-13 |
毛近隆 |
对羟基苯丙烯酸衍生物及其应用
|
WO2010071865A1
(en)
|
2008-12-19 |
2010-06-24 |
Nuon Therapeutics, Inc. |
Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
|
US20100160351A1
(en)
*
|
2008-12-19 |
2010-06-24 |
Nuon Therapeutics, Inc. |
Pharmaceutical compositions and methods for treating hyperuricemia and related disorders
|
GB0903493D0
(en)
|
2009-02-27 |
2009-04-08 |
Vantia Ltd |
New compounds
|
WO2010103039A1
(en)
|
2009-03-10 |
2010-09-16 |
Euro-Celtique S.A. |
Immediate release pharmaceutical compositions comprising oxycodone and naloxone
|
WO2011012622A1
(en)
|
2009-07-30 |
2011-02-03 |
Glaxo Group Limited |
Benzoxazinone derivatives for the treatment of glytl mediated disorders
|
WO2011023753A1
(en)
|
2009-08-27 |
2011-03-03 |
Glaxo Group Limited |
Benzoxazine derivatives as glycine transport inhibitors
|
WO2011032175A1
(en)
|
2009-09-14 |
2011-03-17 |
Nuon Therapeutics, Inc. |
Combination formulations of tranilast and allopurinol and methods related thereto
|
US8859776B2
(en)
|
2009-10-14 |
2014-10-14 |
Merck Sharp & Dohme Corp. |
Substituted piperidines that increase p53 activity and the uses thereof
|
US10668060B2
(en)
|
2009-12-10 |
2020-06-02 |
Collegium Pharmaceutical, Inc. |
Tamper-resistant pharmaceutical compositions of opioids and other drugs
|
WO2011075478A1
(en)
|
2009-12-16 |
2011-06-23 |
N30 Pharmaceuticals, Llc |
Novel thiophene inhibitors of s-nitrosoglutathione reductase
|
GB201000685D0
(en)
|
2010-01-15 |
2010-03-03 |
Glaxo Group Ltd |
Novel compounds
|
TW201201764A
(en)
|
2010-02-01 |
2012-01-16 |
Hospital For Sick Children |
Remote ischemic conditioning for treatment and prevention of restenosis
|
CA2795053A1
(en)
|
2010-03-31 |
2011-10-06 |
The Hospital For Sick Children |
Use of remote ischemic conditioning to improve outcome after myocardial infarction
|
JP2013525448A
(ja)
|
2010-04-27 |
2013-06-20 |
カルシメディカ,インク. |
細胞内カルシウムを調節する化合物
|
WO2011139489A2
(en)
|
2010-04-27 |
2011-11-10 |
Calcimedica Inc. |
Compounds that modulate intracellular calcium
|
GB201007791D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel compounds
|
GB201007789D0
(en)
|
2010-05-10 |
2010-06-23 |
Glaxo Group Ltd |
Novel Compound
|
EP2584903B1
(de)
|
2010-06-24 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Neue heterozyklische verbindungen als erk-hemmer
|
EP2590953B1
(de)
|
2010-07-09 |
2014-10-29 |
Convergence Pharmaceuticals Limited |
Tetrazolverbindungen als calciumkanalblocker
|
JP6043285B2
(ja)
|
2010-08-02 |
2016-12-14 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害
|
RU2624045C2
(ru)
|
2010-08-17 |
2017-06-30 |
Сирна Терапьютикс,Инк |
ОПОСРЕДУЕМОЕ РНК-ИНТЕРФЕРЕНЦИЕЙ ИНГИБИРОВАНИЕ ЭКСПРЕССИИ ГЕНОВ ВИРУСА ГЕПАТИТА B (HBV) С ПРИМЕНЕНИЕМ МАЛОЙ ИНТЕРФЕРИРУЮЩЕЙ НУКЛЕИНОВОЙ КИСЛОТЫ (миНК)
|
PT3333188T
(pt)
|
2010-08-19 |
2022-03-28 |
Zoetis Belgium S A |
Anticorpos de anti-ngf e a sua utilização
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
MX337711B
(es)
|
2010-08-27 |
2016-03-15 |
Calcimedica Inc |
Compuestos que modulan el calcio intracelular.
|
EP2613782B1
(de)
|
2010-09-01 |
2016-11-02 |
Merck Sharp & Dohme Corp. |
Indazolderivate als erk-hemmer
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
EP2632472B1
(de)
|
2010-10-29 |
2017-12-13 |
Sirna Therapeutics, Inc. |
Durch rna-interferenz vermittelte inhibition einer genexpression unter verwendung von short-interfering-nukleinsäuren (sina)
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
CA2991217C
(en)
|
2010-12-22 |
2020-06-09 |
Purdue Pharma L.P. |
Encased tamper resistant controlled release dosage forms
|
JP5638151B2
(ja)
|
2010-12-23 |
2014-12-10 |
パーデュー、ファーマ、リミテッド、パートナーシップ |
不正加工抵抗性の(tamperresistant)固形経口剤形
|
EP2665729B1
(de)
|
2011-01-19 |
2015-04-01 |
Convergence Pharmaceuticals Limited |
Piperazinderivate als cav2.2-calciumkanalblocker
|
CN103732592A
(zh)
|
2011-04-21 |
2014-04-16 |
默沙东公司 |
胰岛素样生长因子-1受体抑制剂
|
US9745373B2
(en)
|
2011-05-20 |
2017-08-29 |
Alderbio Holdings Llc |
Anti-CGRP compositions and use thereof
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
EP2773207B1
(de)
|
2011-10-31 |
2018-03-07 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinone als interleukinrezeptor-assoziierte kinaseinhibitoren
|
GB201122113D0
(en)
|
2011-12-22 |
2012-02-01 |
Convergence Pharmaceuticals |
Novel compounds
|
US20150299696A1
(en)
|
2012-05-02 |
2015-10-22 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
CN107674071B
(zh)
|
2012-05-11 |
2021-12-31 |
同步制药公司 |
作为隐花色素调节剂的含有咔唑的磺酰胺类
|
US9617334B2
(en)
|
2012-06-06 |
2017-04-11 |
Zoetis Services Llc |
Caninized anti-NGF antibodies and methods thereof
|
CA2882950A1
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
WO2014059333A1
(en)
|
2012-10-12 |
2014-04-17 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
RU2660349C2
(ru)
|
2012-11-28 |
2018-07-05 |
Мерк Шарп И Доум Корп. |
Композиции и способы для лечения злокачественной опухоли
|
WO2014100065A1
(en)
|
2012-12-20 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Substituted imidazopyridines as hdm2 inhibitors
|
WO2014120748A1
(en)
|
2013-01-30 |
2014-08-07 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
BR112015017451B1
(pt)
|
2013-02-05 |
2023-01-10 |
Purdue Pharma L.P. |
Formulações farmacêuticas resistentes à violação
|
JP2016514693A
(ja)
|
2013-03-15 |
2016-05-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
ハイブリッド型ネクロトーシス阻害剤
|
US10751287B2
(en)
|
2013-03-15 |
2020-08-25 |
Purdue Pharma L.P. |
Tamper resistant pharmaceutical formulations
|
TWI634114B
(zh)
|
2013-05-08 |
2018-09-01 |
永恒生物科技公司 |
作為激酶抑制劑之呋喃酮化合物
|
US20160166576A1
(en)
|
2013-07-11 |
2016-06-16 |
Merck Sharp & Dohme Corp. |
Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
|
CA2918004C
(en)
|
2013-07-23 |
2018-11-20 |
Euro-Celtique S.A. |
A combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation
|
EP3041938A1
(de)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Kreisförmige polynukleotide
|
WO2015054283A1
(en)
|
2013-10-08 |
2015-04-16 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
KR101446601B1
(ko)
*
|
2014-01-29 |
2014-10-07 |
크리스탈지노믹스(주) |
5-(4-(아미노설포닐)페닐)-2,2-디메틸-4-(3-플루오로페닐)-3(2h)-퓨라논을 포함하는 약학적 조성물 및 캡슐 제형
|
US10413520B2
(en)
|
2014-01-29 |
2019-09-17 |
Crystalgenomics, Inc. |
Oral pharmacological composition including 5-{4-(amino sulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2H)-furanone having crystalline structure with excellent stability
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
GB201417500D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417499D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
GB201417497D0
(en)
|
2014-10-03 |
2014-11-19 |
Convergence Pharmaceuticals |
Novel use
|
RU2563876C1
(ru)
*
|
2014-11-11 |
2015-09-27 |
Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Санкт-Петербургский государственный университет" (СПбГУ) |
Способ получения 2,2-диалкил-4,5-диарилфуран-3(2н)-онов
|
US10329294B2
(en)
|
2015-03-12 |
2019-06-25 |
Merck Sharp & Dohme Corp. |
Pyrazolopyrimidine inhibitors of IRAK4 activity
|
EP3268367B8
(de)
|
2015-03-12 |
2022-11-16 |
Merck Sharp & Dohme LLC |
Carboxamidinhibitoren der irak4-aktivität
|
EP3268003B1
(de)
|
2015-03-12 |
2020-07-29 |
Merck Sharp & Dohme Corp. |
Thienopyrazininhibitoren der irak4-aktivität
|
EP3292213A1
(de)
|
2015-05-04 |
2018-03-14 |
Academisch Medisch Centrum |
Biomarker für den nachweis von aspirinunempfindlichkeit
|
SG11201808630WA
(en)
|
2016-04-15 |
2018-10-30 |
Alder Biopharmaceuticals Inc |
Humanized anti-pacap antibodies and uses thereof
|
WO2017222575A1
(en)
|
2016-06-23 |
2017-12-28 |
Collegium Pharmaceutical, Inc. |
Process of making more stable abuse-deterrent oral formulations
|
BR112019001134A2
(pt)
|
2016-07-21 |
2019-04-30 |
Unilever N.V. |
uso de lactama e composição farmacêutica
|
CN117224534A
(zh)
|
2016-07-21 |
2023-12-15 |
联合利华知识产权控股有限公司 |
用于治疗皮肤损伤的内酰胺
|
US11160787B2
(en)
|
2016-07-21 |
2021-11-02 |
Conopco, Inc. |
4-(4-chlorophenyl)-5-methylene-pyrrol-2-one and 5-methylene-4-(p-tolyl)pyrrol-2-one for use in the treatment of gram negative bacterial infections
|
EP3706742B1
(de)
|
2017-11-08 |
2023-03-15 |
Merck Sharp & Dohme LLC |
Prmt5-inhibitoren
|
MX2020009526A
(es)
|
2018-03-12 |
2020-10-28 |
Zoetis Services Llc |
Anticuerpos anti-ngf y metodos de estos.
|
US20210309688A1
(en)
|
2018-08-07 |
2021-10-07 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2020033282A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
EP3852732A1
(de)
|
2018-09-19 |
2021-07-28 |
ModernaTX, Inc. |
Peg-lipide und deren verwendung
|
US20220031631A1
(en)
|
2018-09-19 |
2022-02-03 |
Modernatx, Inc. |
High-purity peg lipids and uses thereof
|
JP7291220B2
(ja)
|
2018-11-21 |
2023-06-14 |
トレモ― ファーマシューティカルズ,インコーポレーテッド |
ロフェコキシブの精製形態、製造方法および使用
|
CN110452198B
(zh)
*
|
2019-09-03 |
2021-03-26 |
山东鲁抗舍里乐药业有限公司 |
一种非罗考昔的制备方法
|
CN110452199B
(zh)
*
|
2019-09-03 |
2021-03-30 |
山东鲁抗舍里乐药业有限公司 |
一种非罗考昔的制备方法
|
US10945992B1
(en)
|
2019-11-13 |
2021-03-16 |
Tremeau Pharmaceuticals, Inc. |
Dosage forms of rofecoxib and related methods
|
KR20220123229A
(ko)
|
2019-12-17 |
2022-09-06 |
머크 샤프 앤드 돔 엘엘씨 |
Prmt5 억제제
|
CN114014824B
(zh)
*
|
2020-12-09 |
2023-06-13 |
上海科技大学 |
一种杂环化合物的应用
|
EP4306520A1
(de)
*
|
2021-03-11 |
2024-01-17 |
Medshine Discovery Inc. |
Thiophenverbindung und anwendung davon
|
IL305573A
(en)
|
2021-03-15 |
2023-10-01 |
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