DE69334008D1 - Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen - Google Patents

Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen

Info

Publication number
DE69334008D1
DE69334008D1 DE69334008T DE69334008T DE69334008D1 DE 69334008 D1 DE69334008 D1 DE 69334008D1 DE 69334008 T DE69334008 T DE 69334008T DE 69334008 T DE69334008 T DE 69334008T DE 69334008 D1 DE69334008 D1 DE 69334008D1
Authority
DE
Germany
Prior art keywords
treatment
allergic diseases
compound
formula
terfenadine carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69334008T
Other languages
English (en)
Other versions
DE69334008T2 (de
Inventor
James W Young
Nancy M Gray
Raymond L Woosley
Yiwang Chen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sunovion Pharmaceuticals Inc
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27129882&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69334008(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sepracor Inc filed Critical Sepracor Inc
Publication of DE69334008D1 publication Critical patent/DE69334008D1/de
Application granted granted Critical
Publication of DE69334008T2 publication Critical patent/DE69334008T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69334008T 1992-08-03 1993-08-03 Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen Expired - Lifetime DE69334008T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US92418292A 1992-08-03 1992-08-03
US92415692A 1992-08-03 1992-08-03
US924156 1992-08-03
US924182 1992-08-03

Publications (2)

Publication Number Publication Date
DE69334008D1 true DE69334008D1 (de) 2006-05-24
DE69334008T2 DE69334008T2 (de) 2006-10-19

Family

ID=27129882

Family Applications (5)

Application Number Title Priority Date Filing Date
DE69334008T Expired - Lifetime DE69334008T2 (de) 1992-08-03 1993-08-03 Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen
DE69316660T Expired - Lifetime DE69316660T3 (de) 1992-08-03 1993-08-03 Terfanadin Metaboliten und deren optisch reine Isomere zur Behandlung von allergischen Krankheiten
DE9320925U Expired - Lifetime DE9320925U1 (de) 1992-08-03 1993-08-03 Terfenadin-Metabolite und deren optisch reine Isomere für die Behandlung von allergischen Störungen
DE69334145T Expired - Lifetime DE69334145T2 (de) 1992-08-03 1993-08-03 Terfenadincarboxylat und die Behandlung von Hautreizung
DE0701443T Pending DE701443T1 (de) 1992-08-03 1993-08-03 Terfanadin Metaboliten und deren optische reine Isomeren zur Behandlung vonallegischen Krankheiten

Family Applications After (4)

Application Number Title Priority Date Filing Date
DE69316660T Expired - Lifetime DE69316660T3 (de) 1992-08-03 1993-08-03 Terfanadin Metaboliten und deren optisch reine Isomere zur Behandlung von allergischen Krankheiten
DE9320925U Expired - Lifetime DE9320925U1 (de) 1992-08-03 1993-08-03 Terfenadin-Metabolite und deren optisch reine Isomere für die Behandlung von allergischen Störungen
DE69334145T Expired - Lifetime DE69334145T2 (de) 1992-08-03 1993-08-03 Terfenadincarboxylat und die Behandlung von Hautreizung
DE0701443T Pending DE701443T1 (de) 1992-08-03 1993-08-03 Terfanadin Metaboliten und deren optische reine Isomeren zur Behandlung vonallegischen Krankheiten

Country Status (24)

Country Link
US (1) US5375693A (de)
EP (4) EP0815860B1 (de)
JP (6) JP3041954B2 (de)
KR (1) KR950702420A (de)
AT (3) ATE162399T1 (de)
AU (3) AU675240B2 (de)
BR (1) BR9306841A (de)
CA (1) CA2141572C (de)
CZ (1) CZ27495A3 (de)
DE (5) DE69334008T2 (de)
DK (3) DK0815860T3 (de)
ES (3) ES2284740T3 (de)
FI (1) FI950467A (de)
GB (1) GB2284351B (de)
GR (3) GR960300024T1 (de)
HK (1) HK1045806B (de)
HU (1) HU226242B1 (de)
NO (1) NO310644B1 (de)
PL (1) PL174373B1 (de)
PT (2) PT815860E (de)
RO (1) RO116043B1 (de)
RU (1) RU2167657C2 (de)
SK (1) SK12495A3 (de)
WO (1) WO1994003170A1 (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2121084T3 (es) * 1992-05-11 2002-02-16 Merrell Pharma Inc Utilizacion de derivados de terfenadina como antihistaminicos en un paciente que padece de trastornos hepaticos.
DE69334008T2 (de) * 1992-08-03 2006-10-19 Sepracor Inc., Marlborough Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
DE69415319T2 (de) * 1993-06-24 1999-06-10 Albany Molecular Res Inc Verfahren zur herstellung von piperidinderivaten
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate
US20030045722A1 (en) * 1994-05-18 2003-03-06 Henton Daniel R. Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof
EP0766668B1 (de) * 1994-05-18 2002-07-17 Aventis Pharmaceuticals Inc. Verfahren zur herstellung von wasserfreien und hydrat-formen von antihistaminischen piperinderivaten, polymerphe und pseudomorphe davon
US5455049A (en) * 1995-01-04 1995-10-03 Ascent Pharmaceuticals, Inc. Terfenadine oral powder
CN1090935C (zh) * 1995-02-28 2002-09-18 阿温蒂斯药物公司 哌啶子基烷醇化合物的药物组合物
GB9513972D0 (en) * 1995-07-08 1995-09-06 Merck Sharp & Dohme Pharmaceutical compositions
US5906747A (en) * 1995-11-13 1999-05-25 Biosepra Inc. Separation of molecules from dilute solutions using composite chromatography media having high dynamic sorptive capacity at high flow rates
US5908850A (en) * 1995-12-04 1999-06-01 Celgene Corporation Method of treating attention deficit disorders with d-threo methylphenidate
US5837284A (en) * 1995-12-04 1998-11-17 Mehta; Atul M. Delivery of multiple doses of medications
US5733756A (en) * 1996-01-05 1998-03-31 Celgene Corporation Lactams and processes for stereoselective enrichment of lactams, amides, and esters
US6486177B2 (en) * 1995-12-04 2002-11-26 Celgene Corporation Methods for treatment of cognitive and menopausal disorders with D-threo methylphenidate
US6355656B1 (en) 1995-12-04 2002-03-12 Celgene Corporation Phenidate drug formulations having diminished abuse potential
US5922736A (en) 1995-12-04 1999-07-13 Celegene Corporation Chronic, bolus administration of D-threo methylphenidate
US6153754A (en) * 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
ES2124167B1 (es) * 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
US5925761A (en) * 1997-02-04 1999-07-20 Sepracor Inc. Synthesis of terfenadine and derivatives
US6962997B1 (en) * 1997-05-22 2005-11-08 Celgene Corporation Process and intermediates for resolving piperidyl acetamide steroisomers
PL192079B1 (pl) * 1997-08-26 2006-08-31 Aventis Pharmaceuticals Kompozycja farmaceutyczna w postaci dwuwarstwowej tabletki
US6194431B1 (en) 1998-04-14 2001-02-27 Paul D. Rubin Methods and compositions using terfenadine metabolites in combination with leukotriene inhibitors
DE19913862C2 (de) * 1999-03-26 2003-04-10 Forschungszentrum Juelich Gmbh Verfahren zur biokatalysierten Umsetzung schlecht wasserlöslicher Substanzen
DE10007203A1 (de) * 2000-02-17 2001-08-23 Asta Medica Ag Neue Kombination nichtsedierender Antihistaminika mit Substanzen, die die Leukotrienwirkung beeinflussen, zur Behandlung der Rhinitis/Konjunktivitis
US6613907B2 (en) 2000-11-08 2003-09-02 Amr Technology, Inc. Process for the production of piperidine derivatives with microorganisms
CZ20033019A3 (cs) * 2001-04-09 2004-07-14 Teva Pharmaceutical Industries Ltd. Polymorfní formy chloridu fexofenadinu
US20030021849A1 (en) * 2001-04-09 2003-01-30 Ben-Zion Dolitzky Polymorphs of fexofenadine hydrochloride
WO2003020274A1 (en) * 2001-08-30 2003-03-13 Aventis Pharmaceuticals Inc. Treatment of atopic dermatitis
ES2239554T1 (es) * 2002-06-10 2005-10-01 Teva Pharmaceutical Industries Ltd. Forma xvi polimorfica de hidrocloruro de fexofenadina.
US20050026890A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with an antihistamine for treatment of asthma or chronic obstructive pulmonary disease
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
JP4515121B2 (ja) 2004-03-15 2010-07-28 東芝テック株式会社 ワイヤドットプリンタヘッド及びワイヤドットプリンタ
JP4473021B2 (ja) 2004-03-22 2010-06-02 東芝テック株式会社 窒化層形成方法、磁気回路形成部材、アーマチュア、ワイヤドットプリンタヘッド及びワイヤドットプリンタ
MXPA06012281A (es) * 2004-04-26 2007-07-18 Teva Pharma Formas cristalinas de clorhidrato de fexofenadina y procesos para su preparacion.
US20050239830A1 (en) * 2004-04-26 2005-10-27 Vikram Khetani Methods of diminishing co-abuse potential
US7498443B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of carebastine
US7498345B2 (en) 2004-09-17 2009-03-03 Albany Molecular Research, Inc. Process for production of piperidine derivatives
WO2006037042A1 (en) * 2004-09-28 2006-04-06 Teva Pharmaceutical Industries Ltd. Fexofenadine crystal form and processes for its preparation thereof
US20060127421A1 (en) * 2004-12-09 2006-06-15 Celgene Corporation Treatment using D-threo methylphenidate
EP1956906A4 (de) 2005-11-09 2009-12-30 Combinatorx Inc Verfahren, zusammensetzungen und kits für die behandlung von medizinischen beschwerden
NZ580495A (en) * 2007-04-13 2011-05-27 Southern Res Inst Use of anti-angiogenic agents and methods of use, particulary amiodarone for inhibiting or reducing angiogenesis
US20090076080A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched fexofenadine
WO2014052836A2 (en) * 2012-09-27 2014-04-03 Dunman Paul M Methods and compositions for treating infection
EP3973957A1 (de) 2015-03-26 2022-03-30 Sen-Jam Pharmaceutical LLC Verfahren und zusammensetzungen zur hemmung von symptomen im zusammenhang mit veisalgia
DE102017130361A1 (de) 2017-12-18 2019-07-04 Lsp Innovative Automotive Systems Gmbh Statorzahn und Stator mit guter elektrischer Isolierung und gleichzeitig sehr hoher Wärmeleitfähigkeit zur Leistungssteigerung von Elektromotoren

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US880801A (en) † 1908-03-03 Harold Larsen Vibrator.
US922890A (en) † 1907-03-26 1909-05-25 Peder Joergen Hansen Stream-motor.
US4254129A (en) † 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4552899A (en) † 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4829064A (en) † 1987-06-08 1989-05-09 Analgesic Associates Cough/cold mixtures comprising non-sedating antihistamine drugs
US4929605A (en) * 1987-10-07 1990-05-29 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol derivatives
US4996061A (en) † 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
DE69332117T2 (de) * 1992-04-10 2003-01-30 Merrell Pharma Inc 4-diphenylmethylpiperidine und verfahren zu ihrer herstellung
ES2121084T3 (es) 1992-05-11 2002-02-16 Merrell Pharma Inc Utilizacion de derivados de terfenadina como antihistaminicos en un paciente que padece de trastornos hepaticos.
DE69334008T2 (de) 1992-08-03 2006-10-19 Sepracor Inc., Marlborough Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen
DE69415319T2 (de) * 1993-06-24 1999-06-10 Albany Molecular Res Inc Verfahren zur herstellung von piperidinderivaten
KR100333790B1 (ko) * 1993-06-25 2002-11-04 메렐 파마슈티칼스 인크. 항히스타민성4-디페닐메틸/디페닐메톡시피페리딘유도체제조용신규중간체
CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
CA2128821A1 (en) * 1993-07-27 1995-01-28 Dilip J. Gole Freeze-dried pharmaceutical dosage form and process for separation thereof
WO1995010278A1 (en) * 1993-10-15 1995-04-20 Hoechst Marion Roussel, Inc. Treatment of allergic disorders with terfenadine carboxylate

Also Published As

Publication number Publication date
JP2000086513A (ja) 2000-03-28
BR9306841A (pt) 1998-12-08
ATE322899T1 (de) 2006-04-15
EP0815860B1 (de) 2006-04-12
EP0701443B1 (de) 1998-01-21
FI950467A0 (fi) 1995-02-02
JP3288660B2 (ja) 2002-06-04
GB2284351B (en) 1996-11-27
GB2284351A (en) 1995-06-07
ATE363283T1 (de) 2007-06-15
ES2086270T5 (es) 2001-02-01
DE69316660T2 (de) 1998-05-07
HU9500313D0 (en) 1995-03-28
JPH08500348A (ja) 1996-01-16
JP2000086515A (ja) 2000-03-28
JP3288662B2 (ja) 2002-06-04
JP2000086516A (ja) 2000-03-28
DE69316660T3 (de) 2001-04-05
KR950702420A (ko) 1995-07-29
SK12495A3 (en) 1997-01-08
JP3288661B2 (ja) 2002-06-04
WO1994003170A1 (en) 1994-02-17
DK1214937T3 (da) 2007-09-17
RU2167657C2 (ru) 2001-05-27
JP2000086514A (ja) 2000-03-28
PT815860E (pt) 2006-08-31
EP1214937A3 (de) 2002-10-30
GR3035417T3 (en) 2001-05-31
AU4798693A (en) 1994-03-03
EP1688142A1 (de) 2006-08-09
JP3041954B2 (ja) 2000-05-15
ES2284740T3 (es) 2007-11-16
US5375693A (en) 1994-12-27
ES2257757T3 (es) 2006-08-01
JP3037697B2 (ja) 2000-04-24
DE69334145D1 (de) 2007-07-12
DE69316660D1 (de) 1998-02-26
EP0815860A2 (de) 1998-01-07
HUT71889A (en) 1996-02-28
GB9502183D0 (en) 1995-03-22
GR3026530T3 (en) 1998-07-31
RU95107881A (ru) 1996-11-27
FI950467A (fi) 1995-03-31
JP2000086512A (ja) 2000-03-28
EP1214937B1 (de) 2007-05-30
RO116043B1 (ro) 2000-10-30
ES2086270T3 (es) 1998-03-01
AU1842999A (en) 1999-04-29
NO310644B1 (no) 2001-08-06
CZ27495A3 (en) 1996-09-11
DK0701443T3 (da) 1998-02-09
EP0701443A1 (de) 1996-03-20
DK0701443T4 (da) 2000-12-18
GR960300024T1 (en) 1996-05-31
PL307339A1 (en) 1995-05-15
NO950374L (no) 1995-03-29
EP0701443B2 (de) 2000-11-22
EP1214937A2 (de) 2002-06-19
HU226242B1 (en) 2008-07-28
HK1045806B (zh) 2008-03-14
HK1045806A1 (en) 2002-12-13
DE701443T1 (de) 1997-01-30
DK0815860T3 (da) 2006-08-14
ATE162399T1 (de) 1998-02-15
NO950374D0 (no) 1995-02-01
CA2141572C (en) 2001-02-06
DE9320925U1 (de) 1995-08-31
ES2086270T1 (es) 1996-07-01
DE69334145T2 (de) 2008-01-24
CA2141572A1 (en) 1994-02-17
PL174373B1 (pl) 1998-07-31
PT1214937E (pt) 2007-07-25
EP0815860A3 (de) 1998-01-14
AU7182296A (en) 1997-01-30
DE69334008T2 (de) 2006-10-19
AU675240B2 (en) 1997-01-30

Similar Documents

Publication Publication Date Title
DE69334008D1 (de) Terfenadin-Carboxylat und die Behandlung von allergischen Erkrankungen
DE69327328T2 (de) Verwendund von norastemizol zur behandlung der allergischen rhinitis
DE60018409D1 (de) Verwendung von antiseptika zur herstelllung von arzneimitteln zur prophylaxe und behandlung von infektionen und/ oder funktionellen gewebeumformungen im körperinneren
FR2613617B1 (fr) Agents medicamenteux pour la prevention et la therapie des brulures cutanees par rayons, contenant comme principe actif la 2,6-dimethyl-3,5-diethoxycarbonyl-1,4-dihydropyridine
RU94020964A (ru) Электростатический пластырь "элпласт"

Legal Events

Date Code Title Description
8363 Opposition against the patent