DE69333466D1 - Herstellung von transplantatgeweben aus extrazellulärer matrix - Google Patents
Herstellung von transplantatgeweben aus extrazellulärer matrixInfo
- Publication number
- DE69333466D1 DE69333466D1 DE69333466T DE69333466T DE69333466D1 DE 69333466 D1 DE69333466 D1 DE 69333466D1 DE 69333466 T DE69333466 T DE 69333466T DE 69333466 T DE69333466 T DE 69333466T DE 69333466 D1 DE69333466 D1 DE 69333466D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- extracellular matrix
- transplant tissue
- transplant
- tissue
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
- A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92688592A | 1992-08-07 | 1992-08-07 | |
US926885 | 1992-08-07 | ||
PCT/US1993/007364 WO1994003584A1 (en) | 1992-08-07 | 1993-08-05 | Production of graft tissue from extracellular matrix |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69333466D1 true DE69333466D1 (de) | 2004-05-06 |
DE69333466T2 DE69333466T2 (de) | 2004-08-19 |
Family
ID=25453844
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69333466T Expired - Fee Related DE69333466T2 (de) | 1992-08-07 | 1993-08-05 | Herstellung von transplantatgeweben aus extrazellulärer matrix |
Country Status (6)
Country | Link |
---|---|
US (1) | US5893888A (de) |
EP (1) | EP0656939B1 (de) |
JP (2) | JPH07509638A (de) |
CA (1) | CA2141851A1 (de) |
DE (1) | DE69333466T2 (de) |
WO (1) | WO1994003584A1 (de) |
Families Citing this family (62)
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---|---|---|---|---|
US6334872B1 (en) | 1994-02-18 | 2002-01-01 | Organogenesis Inc. | Method for treating diseased or damaged organs |
US5562946A (en) * | 1994-11-02 | 1996-10-08 | Tissue Engineering, Inc. | Apparatus and method for spinning and processing collagen fiber |
US5891558A (en) * | 1994-11-22 | 1999-04-06 | Tissue Engineering, Inc. | Biopolymer foams for use in tissue repair and reconstruction |
US5709934A (en) * | 1994-11-22 | 1998-01-20 | Tissue Engineering, Inc. | Bipolymer foams having extracellular matrix particulates |
US20020095218A1 (en) * | 1996-03-12 | 2002-07-18 | Carr Robert M. | Tissue repair fabric |
US5911942A (en) * | 1995-11-02 | 1999-06-15 | Tissue Engineering, Inc. | Method for spinning and processing collagen fiber |
CN1061812C (zh) * | 1996-04-01 | 2001-02-14 | 胡杰 | 制备皮肤移植体的方法 |
US6545042B2 (en) | 1996-11-05 | 2003-04-08 | Gp Medical | Acellular biological material chemically treated with genipin |
US6998418B1 (en) | 1996-11-05 | 2006-02-14 | Gp Medical, Inc. | Acellular biological material chemically treated with genipin |
US5882929A (en) * | 1998-04-07 | 1999-03-16 | Tissue Engineering, Inc. | Methods and apparatus for the conditioning of cartilage replacement tissue |
JP4341050B2 (ja) * | 1998-06-05 | 2009-10-07 | オルガノジェネシス インク. | 生体工学により作成した血管移植片補綴 |
WO1999062427A1 (en) * | 1998-06-05 | 1999-12-09 | Organogenesis Inc. | Bioengineered vascular graft support prostheses |
AU754437B2 (en) * | 1998-06-05 | 2002-11-14 | Organogenesis Inc. | Bioengineered tubular graft prostheses |
CA2334364C (en) * | 1998-06-05 | 2011-01-04 | Organogenesis Inc. | Bioengineered flat sheet graft prostheses |
ES2330063T3 (es) * | 1998-06-19 | 2009-12-03 | Lifecell Corporation | Matriz tisular acelular particulada. |
US6933326B1 (en) | 1998-06-19 | 2005-08-23 | Lifecell Coporation | Particulate acellular tissue matrix |
DE10026482A1 (de) * | 2000-05-29 | 2001-12-13 | Augustinus Bader | Verfahren zur Herstellung eines bioartifiziellen Transplantats |
AU2001291092B2 (en) * | 2000-09-18 | 2007-08-23 | Organogenesis Inc. | Bioengineered flat sheet graft prosthesis and its use |
AU2002322255A1 (en) * | 2001-06-15 | 2003-01-02 | The Cleveland Clinic Foundation | Tissue engineered mitral valve chrodae and methods of making and using same |
EP1416876B1 (de) * | 2001-07-16 | 2011-03-23 | DePuy Products, Inc. | Poröses freisetzungsgerüst und verfahren |
JP2004535245A (ja) * | 2001-07-16 | 2004-11-25 | デピュイ・プロダクツ・インコーポレイテッド | 多孔質細胞外基質支持骨格材料および方法 |
AU2002320512B2 (en) * | 2001-07-16 | 2008-01-31 | Depuy Products, Inc. | Cartilage repair and regeneration device and method |
JP2003193328A (ja) * | 2001-12-19 | 2003-07-09 | Nipro Corp | コラーゲン単糸の製造方法 |
JP2004305260A (ja) * | 2003-04-02 | 2004-11-04 | Olympus Corp | 生体組織補填体とその製造方法 |
US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
US7488348B2 (en) * | 2003-05-16 | 2009-02-10 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
US7097579B2 (en) | 2003-10-15 | 2006-08-29 | Borgwarner Inc. | Pivoting chain guide and tensioner assembly |
EP1689321B1 (de) | 2003-11-07 | 2017-01-04 | The University of Connecticut | Künstliche gewebesysteme und ihre verwendungen |
US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
US9138445B2 (en) * | 2005-03-09 | 2015-09-22 | Cook Biotech Incorporated | Medical graft materials with adherent extracellular matrix fibrous mass |
JP4356654B2 (ja) * | 2005-06-02 | 2009-11-04 | ニプロ株式会社 | コラーゲン単糸の製造方法 |
US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
WO2007035778A2 (en) | 2005-09-19 | 2007-03-29 | Histogenics Corporation | Cell-support matrix and a method for preparation thereof |
WO2007034843A1 (ja) * | 2005-09-20 | 2007-03-29 | National Institute For Materials Science | 多孔質基盤体とその製造方法並びに多孔質基盤体の使用方法 |
US7871440B2 (en) | 2006-12-11 | 2011-01-18 | Depuy Products, Inc. | Unitary surgical device and method |
US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
ES2714365T3 (es) * | 2007-07-10 | 2019-05-28 | Lifecell Corp | Composiciones acelulares de matriz tisular para reparación de tejidos |
EP2265220A1 (de) | 2008-03-05 | 2010-12-29 | Musculoskeletal Transplant Foundation | Spongiosa-konstrukte, knorpelteilchen und kombinationen von spongiosa-konstrukten und knorpelteilchen |
US8469779B1 (en) | 2009-01-02 | 2013-06-25 | Lifecell Corporation | Method for debristling animal skin |
WO2011108517A1 (ja) * | 2010-03-01 | 2011-09-09 | 富士フイルム株式会社 | 生体親和性を有する高分子ブロックと細胞からなる細胞構造体 |
US9089523B2 (en) | 2011-07-28 | 2015-07-28 | Lifecell Corporation | Natural tissue scaffolds as tissue fillers |
US9532863B2 (en) | 2011-12-20 | 2017-01-03 | Lifecell Corporation | Sheet tissue products |
ES2726105T3 (es) * | 2011-12-20 | 2019-10-01 | Lifecell Corp | Productos de tejido fluidizable |
DK2806907T3 (en) | 2012-01-24 | 2019-02-18 | Lifecell Corp | EXTENDED TISSUE MATRIX |
ES2753156T3 (es) | 2012-07-13 | 2020-04-07 | Lifecell Corp | Procedimientos de tratamiento mejorado de tejido adiposo |
WO2014052376A1 (en) | 2012-09-26 | 2014-04-03 | Lifecell Corporation | Processed adipose tissue |
CN104994893B (zh) | 2013-02-06 | 2018-01-05 | 生命细胞公司 | 用于组织产物的局部改性的方法 |
US10405961B2 (en) | 2013-03-14 | 2019-09-10 | Cell and Molecular Tissue Engineering, LLC | Coated surgical mesh, and corresponding systems and methods |
US10130288B2 (en) | 2013-03-14 | 2018-11-20 | Cell and Molecular Tissue Engineering, LLC | Coated sensors, and corresponding systems and methods |
JP6515304B2 (ja) * | 2013-05-07 | 2019-05-22 | 国立大学法人 東京医科歯科大学 | 粒子状脱細胞化組織の製造方法 |
CA2919374C (en) | 2013-07-30 | 2019-12-03 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US10524895B2 (en) * | 2014-10-10 | 2020-01-07 | Orthocell Limited | Collagen construct and method for producing the collagen construct |
US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
US9238090B1 (en) | 2014-12-24 | 2016-01-19 | Fettech, Llc | Tissue-based compositions |
US10912864B2 (en) | 2015-07-24 | 2021-02-09 | Musculoskeletal Transplant Foundation | Acellular soft tissue-derived matrices and methods for preparing same |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
US10792394B2 (en) | 2016-06-03 | 2020-10-06 | Lifecell Corporation | Methods for localized modification of tissue products |
RU2627844C1 (ru) * | 2016-10-24 | 2017-08-14 | Общество С Ограниченной Ответственностью "Ниармедик Плюс" | Способ получения суспензионной формы измельченного децеллюляризованного внеклеточного матрикса |
AU2017382173A1 (en) | 2016-12-22 | 2019-06-06 | Lifecell Corporation | Devices and methods for tissue cryomilling |
CN110664509A (zh) * | 2019-10-21 | 2020-01-10 | 南方医科大学 | 一种植入耳支架及其制备方法 |
EP4070824A1 (de) | 2021-04-09 | 2022-10-12 | Regen i Göteborg AB | Meeresgerüste zur erzeugung menschlicher gewebe |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4642292A (en) * | 1979-10-29 | 1987-02-10 | Albert Einstein College Of Medicine Of Yeshiva University, A Division Of Yeshiva University | Method for isolation of connective tissue biomatrix |
US4501815A (en) * | 1979-10-29 | 1985-02-26 | Albert Einstein College Of Medicine Of Yeshiva University | Article for culturing differentiated cells |
US4505266A (en) * | 1981-10-26 | 1985-03-19 | Massachusetts Institute Of Technology | Method of using a fibrous lattice |
US4485096A (en) * | 1982-02-26 | 1984-11-27 | Massachusetts Institute Of Technology | Tissue-equivalent and method for preparation thereof |
US4485097A (en) * | 1982-05-26 | 1984-11-27 | Massachusetts Institute Of Technology | Bone-equivalent and method for preparation thereof |
US4661111A (en) * | 1982-08-04 | 1987-04-28 | La Jolla Cancer Research Foundation | Polypeptide |
US4645669A (en) * | 1982-10-04 | 1987-02-24 | Albert Einstein College Of Medicine Of Yeshiva University | Culturing and emplacement of differentiated cells in vivo |
US4801299A (en) * | 1983-06-10 | 1989-01-31 | University Patents, Inc. | Body implants of extracellular matrix and means and methods of making and using such implants |
US4837285A (en) * | 1984-03-27 | 1989-06-06 | Medimatrix | Collagen matrix beads for soft tissue repair |
US5032508A (en) * | 1988-09-08 | 1991-07-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
GB8618374D0 (en) * | 1986-07-28 | 1986-09-03 | Hsc Res Dev Corp | Biological vascular prostheses |
US4795459A (en) * | 1987-05-18 | 1989-01-03 | Rhode Island Hospital | Implantable prosthetic device with lectin linked endothelial cells |
FR2617488B1 (fr) * | 1987-07-01 | 1990-03-09 | Tab | Procede de fabrication de structures organisees de collagene, notamment d'origine humaine, et structures organisees de collagene correspondantes |
US4969912A (en) * | 1988-02-18 | 1990-11-13 | Kelman Charles D | Human collagen processing and autoimplant use |
US5201745A (en) * | 1988-03-15 | 1993-04-13 | Imedex | Visceral surgery patch |
US5110604A (en) * | 1988-06-30 | 1992-05-05 | Collagen Corporation | Processes for producing collagen matrixes and methods of using same |
US4950483A (en) * | 1988-06-30 | 1990-08-21 | Collagen Corporation | Collagen wound healing matrices and process for their production |
US5024841A (en) * | 1988-06-30 | 1991-06-18 | Collagen Corporation | Collagen wound healing matrices and process for their production |
US4902508A (en) * | 1988-07-11 | 1990-02-20 | Purdue Research Foundation | Tissue graft composition |
US5171273A (en) * | 1989-01-13 | 1992-12-15 | University Of Medicine And Dentistry Of New Jersey | Synthetic collagen orthopaedic structures such as grafts, tendons and other structures |
US5026381A (en) * | 1989-04-20 | 1991-06-25 | Colla-Tec, Incorporated | Multi-layered, semi-permeable conduit for nerve regeneration comprised of type 1 collagen, its method of manufacture and a method of nerve regeneration using said conduit |
US5378469A (en) * | 1990-04-06 | 1995-01-03 | Organogenesis, Inc. | Collagen threads |
US5192312A (en) * | 1991-03-05 | 1993-03-09 | Colorado State University Research Foundation | Treated tissue for implantation and methods of treatment and use |
US5562946A (en) * | 1994-11-02 | 1996-10-08 | Tissue Engineering, Inc. | Apparatus and method for spinning and processing collagen fiber |
-
1993
- 1993-08-05 EP EP93919888A patent/EP0656939B1/de not_active Expired - Lifetime
- 1993-08-05 JP JP6505561A patent/JPH07509638A/ja not_active Ceased
- 1993-08-05 WO PCT/US1993/007364 patent/WO1994003584A1/en active IP Right Grant
- 1993-08-05 CA CA002141851A patent/CA2141851A1/en not_active Abandoned
- 1993-08-05 DE DE69333466T patent/DE69333466T2/de not_active Expired - Fee Related
-
1994
- 1994-09-06 US US08/302,087 patent/US5893888A/en not_active Expired - Fee Related
-
2002
- 2002-06-10 JP JP2002169194A patent/JP2003047652A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
US5893888A (en) | 1999-04-13 |
CA2141851A1 (en) | 1994-02-17 |
JPH07509638A (ja) | 1995-10-26 |
WO1994003584A1 (en) | 1994-02-17 |
JP2003047652A (ja) | 2003-02-18 |
EP0656939B1 (de) | 2004-03-31 |
DE69333466T2 (de) | 2004-08-19 |
EP0656939A1 (de) | 1995-06-14 |
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