DE69331176T2 - Knochenzement und Verfahren zu seiner Herstellung - Google Patents

Knochenzement und Verfahren zu seiner Herstellung

Info

Publication number
DE69331176T2
DE69331176T2 DE69331176T DE69331176T DE69331176T2 DE 69331176 T2 DE69331176 T2 DE 69331176T2 DE 69331176 T DE69331176 T DE 69331176T DE 69331176 T DE69331176 T DE 69331176T DE 69331176 T2 DE69331176 T2 DE 69331176T2
Authority
DE
Germany
Prior art keywords
manufacture
bone cement
cement
bone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69331176T
Other languages
English (en)
Other versions
DE69331176D1 (de
Inventor
Steve T Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zimmer Inc
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of DE69331176D1 publication Critical patent/DE69331176D1/de
Application granted granted Critical
Publication of DE69331176T2 publication Critical patent/DE69331176T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K9/00—Use of pretreated ingredients
    • C08K9/10—Encapsulated ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0089—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing inorganic fillers not covered by groups A61L24/0078 or A61L24/0084
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/44—Radioisotopes, radionuclides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/62—Encapsulated active agents, e.g. emulsified droplets
    • A61L2300/622—Microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
DE69331176T 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung Expired - Lifetime DE69331176T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/921,030 US5334626A (en) 1992-07-28 1992-07-28 Bone cement composition and method of manufacture

Publications (2)

Publication Number Publication Date
DE69331176D1 DE69331176D1 (de) 2002-01-03
DE69331176T2 true DE69331176T2 (de) 2002-07-11

Family

ID=25444810

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69331176T Expired - Lifetime DE69331176T2 (de) 1992-07-28 1993-07-28 Knochenzement und Verfahren zu seiner Herstellung

Country Status (6)

Country Link
US (2) US5334626A (de)
EP (1) EP0581387B1 (de)
JP (2) JPH0678987A (de)
AU (1) AU666191B2 (de)
CA (1) CA2098082C (de)
DE (1) DE69331176T2 (de)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6080801A (en) * 1990-09-13 2000-06-27 Klaus Draenert Multi-component material and process for its preparation
KR0139235B1 (ko) * 1994-01-29 1998-04-28 조세현 정형외과용 세멘트 비드조성물 및 그의 제조방법
US20020032298A1 (en) * 1994-07-22 2002-03-14 Bennett Steven L. Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6339130B1 (en) * 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US5578662A (en) 1994-07-22 1996-11-26 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
AU5973496A (en) * 1995-06-06 1996-12-24 Merck & Co., Inc. Bisphosphonate cement composition to prevent aseptic loosening of orthopedic implant devices
US5795922A (en) * 1995-06-06 1998-08-18 Clemson University Bone cement composistion containing microencapsulated radiopacifier and method of making same
US5942559A (en) * 1996-08-26 1999-08-24 Ivoclar Ag Dental light-curing opaquer
US5756127A (en) * 1996-10-29 1998-05-26 Wright Medical Technology, Inc. Implantable bioresorbable string of calcium sulfate beads
US5902839A (en) * 1996-12-02 1999-05-11 Northwestern University Bone cement and method of preparation
US6713527B2 (en) * 1997-02-07 2004-03-30 Queen's University At Kingston Anaesthetic bone cement
US5847046A (en) * 1997-03-12 1998-12-08 United States Surgical Corporation Biodegradable bone cement
US6309420B1 (en) * 1997-10-14 2001-10-30 Parallax Medical, Inc. Enhanced visibility materials for implantation in hard tissue
US6020396A (en) * 1998-03-13 2000-02-01 The Penn State Research Foundation Bone cement compositions
WO2000057932A2 (en) * 1999-03-31 2000-10-05 The Brigham And Women's Hospital, Inc. Nanocomposite surgical materials and method of producing them
US7371408B1 (en) 1999-06-07 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
CA2287112C (en) 1999-09-02 2008-02-19 Kieran Murphy Method and apparatus for strengthening vertebral bodies
DE60207051D1 (de) * 2001-01-26 2005-12-08 Univ Mississippi Medical Ct Ja Knochenzement
US7008433B2 (en) 2001-02-15 2006-03-07 Depuy Acromed, Inc. Vertebroplasty injection device
EP1492475B1 (de) * 2001-04-16 2011-12-21 Wright Medical Technology, Inc. Dichte/poröse strukturen zur verwendung als knochenersatz
ITVI20010126A1 (it) * 2001-05-30 2002-11-30 Tecres Spa Cemento osseo radiopaco per uso ortopedico nonche' metodo di realizzazione
US7371409B2 (en) 2001-09-06 2008-05-13 Wright Medical Technology, Inc. Bone graft substitute composition
DE60335248D1 (de) 2002-03-29 2011-01-20 Wright Medical Tech Inc Knochentransplantat-ersatzzusammensetzung
US6652887B1 (en) 2002-06-24 2003-11-25 Wright Medical Technology, Inc. Bone graft substitute composition
US7291179B2 (en) 2002-06-24 2007-11-06 Wright Medical Technology, Inc. Bone graft substitute composition
WO2004039857A1 (en) * 2002-10-28 2004-05-13 Tyco Healthcare Group Lp Bioabsorbable adhesive compounds
US7507257B2 (en) * 2003-02-04 2009-03-24 Wright Medical Technology, Inc. Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects
EP1614403B2 (de) 2003-03-14 2014-06-18 Depuy Spine, Inc. Hydraulische vorrichtung zur knochenzementeinspritzung bei perkutaner vertebroplastie
US8066713B2 (en) 2003-03-31 2011-11-29 Depuy Spine, Inc. Remotely-activated vertebroplasty injection device
WO2006011152A2 (en) 2004-06-17 2006-02-02 Disc-O-Tech Medical Technologies, Ltd. Methods for treating bone and other tissue
IL166017A0 (en) * 2004-12-28 2006-01-15 Disc O Tech Medical Tech Ltd Materials devices and methods for treating bones
US8415407B2 (en) 2004-03-21 2013-04-09 Depuy Spine, Inc. Methods, materials, and apparatus for treating bone and other tissue
US8579908B2 (en) 2003-09-26 2013-11-12 DePuy Synthes Products, LLC. Device for delivering viscous material
CA2558200A1 (en) 2004-03-02 2005-09-15 Nanotherapeutics, Inc. Compositions for repairing bone and methods for preparing and using such compositions
US7621952B2 (en) * 2004-06-07 2009-11-24 Dfine, Inc. Implants and methods for treating bone
US20060095138A1 (en) * 2004-06-09 2006-05-04 Csaba Truckai Composites and methods for treating bone
US20060106459A1 (en) * 2004-08-30 2006-05-18 Csaba Truckai Bone treatment systems and methods
DE102004049121B4 (de) * 2004-10-07 2008-01-10 Heraeus Kulzer Gmbh Antibiotikum-/Antibiotika enthaltender PMMA-Knochenzement
US7250550B2 (en) * 2004-10-22 2007-07-31 Wright Medical Technology, Inc. Synthetic bone substitute material
US8048083B2 (en) 2004-11-05 2011-11-01 Dfine, Inc. Bone treatment systems and methods
US7722620B2 (en) 2004-12-06 2010-05-25 Dfine, Inc. Bone treatment systems and methods
US9381024B2 (en) 2005-07-31 2016-07-05 DePuy Synthes Products, Inc. Marked tools
IL174347A0 (en) * 2005-07-31 2006-08-20 Disc O Tech Medical Tech Ltd Bone cement and methods of use thereof
US9918767B2 (en) 2005-08-01 2018-03-20 DePuy Synthes Products, Inc. Temperature control system
US8777479B2 (en) 2008-10-13 2014-07-15 Dfine, Inc. System for use in bone cement preparation and delivery
US8540723B2 (en) 2009-04-14 2013-09-24 Dfine, Inc. Medical system and method of use
DE102005040429A1 (de) * 2005-08-25 2007-03-01 Heraeus Kulzer Gmbh Wirkstofffreisetzungssystem und seine Verwendung
US8025903B2 (en) * 2005-09-09 2011-09-27 Wright Medical Technology, Inc. Composite bone graft substitute cement and articles produced therefrom
KR101270876B1 (ko) * 2005-09-09 2013-06-07 아그노보스 헬스케어 엘엘씨 복합 골이식 대용 시멘트 및 그로부터 제조된 물품
US8360629B2 (en) 2005-11-22 2013-01-29 Depuy Spine, Inc. Mixing apparatus having central and planetary mixing elements
WO2007089739A2 (en) * 2006-01-27 2007-08-09 Stryker Corporation Low pressure delivery system and method for delivering a solid and liquid mixture into a target site for medical treatment
US20070233249A1 (en) * 2006-02-07 2007-10-04 Shadduck John H Methods for treating bone
US7918889B2 (en) * 2006-02-27 2011-04-05 Warsaw Orthopedic, Inc. Expandable spinal prosthetic devices and associated methods
WO2007106256A2 (en) * 2006-03-01 2007-09-20 Poly-Med, Inc. Antimicrobial, radiopaque, microfiber-reinforced, polymeric methacrylate bone cement
US8685421B2 (en) 2006-07-07 2014-04-01 Surmodics, Inc. Beaded wound spacer device
US9072808B2 (en) * 2006-07-17 2015-07-07 Syracuse University Multi-solution bone cements and methods of making the same
US8383734B2 (en) * 2006-07-17 2013-02-26 Syracuse University Multi-solution bone cements and methods of making the same
US8575274B2 (en) * 2006-07-17 2013-11-05 Syracuse University Multi-solution bone cements and methods of making the same
AU2011226788B2 (en) * 2006-09-14 2013-07-25 Depuy Spine, Inc. Bone Cement and Methods of Use Thereof
CN101516412B (zh) * 2006-09-14 2014-02-12 德普伊斯派尔公司 骨水泥及其使用方法
AU2007311451A1 (en) 2006-10-19 2008-04-24 Depuy Spine, Inc. Fluid delivery system
US20100233225A1 (en) * 2007-02-09 2010-09-16 Bingyun Li Method of surface coating devices to incorporate bioactive molecules
WO2008137428A2 (en) 2007-04-30 2008-11-13 Dfine, Inc. Bone treatment systems and methods
US7883511B2 (en) * 2007-09-12 2011-02-08 Fernyhough Jeffrey C Method and composition for use in reinforcing bone
US8500947B2 (en) 2007-11-15 2013-08-06 Covidien Lp Speeding cure rate of bioadhesives
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
WO2009073209A1 (en) * 2007-12-06 2009-06-11 Osseon Therapeutics, Inc. Vertebroplasty implant with enhanced interfacial shear strength
US20090202609A1 (en) * 2008-01-06 2009-08-13 Keough Steven J Medical device with coating composition
US9445854B2 (en) * 2008-02-01 2016-09-20 Dfine, Inc. Bone treatment systems and methods
EP2252336B1 (de) * 2008-02-28 2014-06-25 Dfine, Inc. Knochenbehandlungssysteme und -verfahren
US9180416B2 (en) 2008-04-21 2015-11-10 Dfine, Inc. System for use in bone cement preparation and delivery
WO2010005442A1 (en) * 2008-07-11 2010-01-14 Syracuse University Multi-solution bone cements and methods of making the same
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
WO2011137377A1 (en) 2010-04-29 2011-11-03 Dfine, Inc. System for use in treatment of vertebral fractures
EP2908870B1 (de) 2012-10-16 2018-05-23 SurModics, Inc. Wundverpackungsvorrichtung und -verfahren
CA2921978A1 (en) * 2013-09-30 2015-04-02 Lucite International Speciality Polymers & Resins Limited A hardenable multi-part acrylic composition
US10201457B2 (en) 2014-08-01 2019-02-12 Surmodics, Inc. Wound packing device with nanotextured surface
CN104906640A (zh) * 2015-06-15 2015-09-16 东华大学 一种可显影的生物降解医用捆扎带及其制备方法
JP2019534130A (ja) 2016-10-27 2019-11-28 ディーファイン，インコーポレイティド セメント送達チャネルを有する関節接合型骨刀
US11116570B2 (en) 2016-11-28 2021-09-14 Dfine, Inc. Tumor ablation devices and related methods
WO2018107036A1 (en) 2016-12-09 2018-06-14 Dfine, Inc. Medical devices for treating hard tissues and related methods
WO2018129180A1 (en) 2017-01-06 2018-07-12 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
WO2018181822A1 (ja) 2017-03-31 2018-10-04 三井化学株式会社 硬組織補修用組成物及び硬組織補修用キット
EP3603684B1 (de) * 2017-03-31 2023-03-22 Mitsui Chemicals, Inc. Hartgewebereparaturzusammensetzung und hartgewebereparaturkit
EP3876856A4 (de) 2018-11-08 2022-10-12 Dfine, Inc. Tumorablationsvorrichtung sowie zugehörige systeme und verfahren

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3715331A (en) * 1970-05-01 1973-02-06 Coe Labor Monomer soluble x-ray opaque methacrylate particles
US4045403A (en) * 1972-07-19 1977-08-30 General Electric Company Method of compounding thermo-plastic polymeric materials and fillers
US4404327A (en) * 1979-10-31 1983-09-13 Crugnola Aldo M Orthopaedic cement from acrylate polymers
US4341691A (en) * 1980-02-20 1982-07-27 Zimmer, Inc. Low viscosity bone cement
DE3128923A1 (de) * 1981-07-22 1983-02-10 Beiersdorf Ag, 2000 Hamburg Pulvermischung fuer chirurgische zwecke
US4547390A (en) * 1982-03-12 1985-10-15 Medical Biological Sciences, Inc. Process of making implantable prosthesis material of modified polymeric acrylic (PMMA) beads coated with PHEMA and barium sulfate
JPS59500453A (ja) * 1982-03-12 1984-03-22 ユナイテイド　ステイツ　サ−ジカル　コ−ポレイシヨン 高分子アクリル人工器官
US4535485A (en) * 1982-03-12 1985-08-20 Medical Biological Sciences, Inc. Polymeric acrylic prothesis
US4500658A (en) * 1983-06-06 1985-02-19 Austenal International, Inc. Radiopaque acrylic resin
DE3341888A1 (de) * 1983-11-19 1985-05-30 Bayer Ag, 5090 Leverkusen Anorganisch-organische fuellstoffe, verfahren zu deren herstellung sowie deren verwendung in polymerisierbaren massen
KR920006865B1 (ko) * 1984-05-18 1992-08-21 워싱톤 유니버시티 테크놀러지 어소우시에이츠 인코오퍼레이티드 입자나 액적을 피복하는 방법과 장치
GB8524152D0 (en) * 1985-10-01 1985-11-06 Cole Polymers Ltd Bone cement
US5051482A (en) * 1986-11-19 1991-09-24 Laboratorium Fur Experimentelle Chirurgie Method and apparatus for preparing a self-curing two-component powder liquid bone cement
US4837279A (en) * 1988-02-22 1989-06-06 Pfizer Hospital Products Corp, Inc. Bone cement
US5061520A (en) * 1990-10-05 1991-10-29 Kv Pharmaceutical Company Particle enrobing process and apparatus
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer

Also Published As

Publication number Publication date
CA2098082A1 (en) 1994-01-29
EP0581387A1 (de) 1994-02-02
DE69331176D1 (de) 2002-01-03
US5512610A (en) 1996-04-30
AU3984093A (en) 1994-02-03
EP0581387B1 (de) 2001-11-21
JP2003160372A (ja) 2003-06-03
CA2098082C (en) 2004-11-23
AU666191B2 (en) 1996-02-01
JPH0678987A (ja) 1994-03-22
JP3670637B2 (ja) 2005-07-13
US5334626A (en) 1994-08-02

Similar Documents

Publication Publication Date Title
DE69331176T2 (de) Knochenzement und Verfahren zu seiner Herstellung
DE69129746T2 (de) Modifiziertes Polysilazan und Verfahren zu seiner Herstellung
DE69214306D1 (de) Organopentasiloxan und Verfahren zu seiner Herstellung
DE69420383D1 (de) Schwingungsdämpfendes Material und Verfahren zu seiner Herstellung
DE69406502D1 (de) Weiches Seidenpapier und Verfahren zu seiner Herstellung
DE69411632D1 (de) Filtermaterial und Verfahren zu seiner Herstellung
DE69225439D1 (de) Verdichter und Verfahren zu seiner Herstellung
ATE238310T1 (de) Kristalline substanz von pivoxilcefditoren und verfahren zu ihrer herstellung
DE69411694D1 (de) Durchsichtiger Gegenstand und Verfahren zu seiner Herstellung
DE69032447T2 (de) Thermistor und Verfahren zu seiner Herstellung
DE69613323T2 (de) Gleitwerkstoff und Verfahren zu seiner Herstellung
DE69301771D1 (de) T-Butyl-R-(-)-4-cyano-3-hydroxybutyrat und Verfahren zu seiner Herstellung
DE69433156D1 (de) Varistor und Verfahren zu seiner Herstellung
DE59606485D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE69404221T2 (de) Bügeleisen und Verfahren zu seiner Herstellung
DE59606489D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE59307440D1 (de) Schamottestein und Verfahren zu seiner Herstellung
DE69530633D1 (de) Thyristor und Verfahren zu seiner Herstellung
DE59606657D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE69227674T2 (de) Brotaufstrich und Verfahren zu dessen Herstellung
DE69511319D1 (de) Clinoptilolit und Verfahren zu seiner Herstellung
DE69328047T2 (de) Prothese und Verfahren zur deren Herstellung
DE59606488D1 (de) Verfahren zur Herstellung von Poly-o-hydroxyamiden und Poly-o-mercaptoamiden
DE69606123D1 (de) Verfahren zur Herstellung von Wismutverbindungen und Wismutverbindungen
DE69419516D1 (de) Verfahren zur herstellung von hexafluorocyclobuten und verfahren zur herstellung von hexafluorocyclobutan

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ZIMMER, INC. (N.D.GES.D. STAATES DELAWARE), WA, US