US5912015A
(en)
|
1992-03-12 |
1999-06-15 |
Alkermes Controlled Therapeutics, Inc. |
Modulated release from biocompatible polymers
|
US5656297A
(en)
*
|
1992-03-12 |
1997-08-12 |
Alkermes Controlled Therapeutics, Incorporated |
Modulated release from biocompatible polymers
|
US5716644A
(en)
*
|
1992-06-11 |
1998-02-10 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
US6514533B1
(en)
|
1992-06-11 |
2003-02-04 |
Alkermas Controlled Therapeutics, Inc. |
Device for the sustained release of aggregation-stabilized, biologically active agent
|
US5711968A
(en)
|
1994-07-25 |
1998-01-27 |
Alkermes Controlled Therapeutics, Inc. |
Composition and method for the controlled release of metal cation-stabilized interferon
|
US5674534A
(en)
*
|
1992-06-11 |
1997-10-07 |
Alkermes, Inc. |
Composition for sustained release of non-aggregated erythropoietin
|
DK0674506T3
(da)
*
|
1992-12-02 |
2001-01-08 |
Alkermes Inc |
Væksthormonholdige mikrosfærer med styret frigivelse
|
US6090925A
(en)
|
1993-03-09 |
2000-07-18 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
US5981719A
(en)
|
1993-03-09 |
1999-11-09 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
US6087324A
(en)
*
|
1993-06-24 |
2000-07-11 |
Takeda Chemical Industries, Ltd. |
Sustained-release preparation
|
US6080429A
(en)
*
|
1993-10-25 |
2000-06-27 |
Genentech, Inc. |
Method for drying microspheres
|
US6913767B1
(en)
|
1993-10-25 |
2005-07-05 |
Genentech, Inc. |
Compositions for microencapsulation of antigens for use as vaccines
|
ATE197398T1
(de)
*
|
1994-09-09 |
2000-11-11 |
Takeda Chemical Industries Ltd |
Zubereitung mit verzögerter freigabe eines metallsalz eines peptids
|
ATE204468T1
(de)
*
|
1995-06-07 |
2001-09-15 |
Alkermes Inc |
Mittel zur verzögerten freisetzung von menschlichem wachstumshormon
|
EP1080718A1
(de)
*
|
1995-06-07 |
2001-03-07 |
Alkermes Controlled Therapeutics, Inc. |
Zusammensetzung zur verzögerten Abgabe von menschlichem Wachstumshormon
|
WO1996040074A2
(en)
*
|
1995-06-07 |
1996-12-19 |
Alkermes Controlled Therapeutics, Inc. |
Device for releasing aggregation-stabilized, biologically active agent
|
ATE268591T1
(de)
|
1995-06-27 |
2004-06-15 |
Takeda Chemical Industries Ltd |
Verfahren zur herstellung von zubereitungen mit verzögerter freisetzung
|
EP0850051A2
(de)
*
|
1995-08-31 |
1998-07-01 |
Alkermes Controlled Therapeutics, Inc. |
Mittel zur verzögerten freisetzung eines wirkstoffs
|
SE505146C2
(sv)
*
|
1995-10-19 |
1997-06-30 |
Biogram Ab |
Partiklar för fördröjd frisättning
|
KR100210509B1
(ko)
*
|
1996-01-10 |
1999-07-15 |
성재갑 |
지속성 동물 성장 호르몬 제형 및 이의 제조 방법
|
DE69717263T2
(de)
|
1996-03-28 |
2003-07-24 |
Takeda Chemical Industries Ltd |
Zubereitung mit verzögerter freisetzung und deren herstellung
|
US6495579B1
(en)
|
1996-12-02 |
2002-12-17 |
Angiotech Pharmaceuticals, Inc. |
Method for treating multiple sclerosis
|
US6515016B2
(en)
*
|
1996-12-02 |
2003-02-04 |
Angiotech Pharmaceuticals, Inc. |
Composition and methods of paclitaxel for treating psoriasis
|
DE69705746T2
(de)
|
1996-12-20 |
2001-10-31 |
Alza Corp |
Injizierbare depotgelzubereitung und herstellungsverfahren
|
EP0946169B1
(de)
|
1996-12-20 |
2003-02-26 |
Takeda Chemical Industries, Ltd. |
Verfahren zur herstellung einer zusammensetzung mit verzoegerter abgabe
|
US6306826B1
(en)
|
1997-06-04 |
2001-10-23 |
The Regents Of The University Of California |
Treatment of heart failure with growth hormone
|
US5989463A
(en)
|
1997-09-24 |
1999-11-23 |
Alkermes Controlled Therapeutics, Inc. |
Methods for fabricating polymer-based controlled release devices
|
US6191107B1
(en)
|
1997-09-26 |
2001-02-20 |
Takeda Chemical Industries, Ltd. |
Complex of human growth hormone and zinc
|
US20060165606A1
(en)
|
1997-09-29 |
2006-07-27 |
Nektar Therapeutics |
Pulmonary delivery particles comprising water insoluble or crystalline active agents
|
US20020017295A1
(en)
*
|
2000-07-07 |
2002-02-14 |
Weers Jeffry G. |
Phospholipid-based powders for inhalation
|
US6565885B1
(en)
|
1997-09-29 |
2003-05-20 |
Inhale Therapeutic Systems, Inc. |
Methods of spray drying pharmaceutical compositions
|
US6309623B1
(en)
|
1997-09-29 |
2001-10-30 |
Inhale Therapeutic Systems, Inc. |
Stabilized preparations for use in metered dose inhalers
|
SE512663C2
(sv)
|
1997-10-23 |
2000-04-17 |
Biogram Ab |
Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
|
JP2001507722A
(ja)
*
|
1997-11-06 |
2001-06-12 |
オーボン コーポレイション |
薬物送達のための安定化乾燥薬学的組成物、およびそれを調製する方法
|
JP2001522812A
(ja)
|
1997-11-07 |
2001-11-20 |
カイロン コーポレイション |
Igf−1持続放出性処方物の作製方法
|
US6168570B1
(en)
*
|
1997-12-05 |
2001-01-02 |
Micrus Corporation |
Micro-strand cable with enhanced radiopacity
|
EP2050762A3
(de)
|
1998-03-10 |
2009-07-08 |
Genentech, Inc. |
Neue Polypeptide und für diese kodierende Nukleinsäuren
|
US20030180368A1
(en)
*
|
1998-03-14 |
2003-09-25 |
Cenes Drug Delivery Limited |
Production of microparticles
|
US6733767B2
(en)
|
1998-03-19 |
2004-05-11 |
Merck & Co., Inc. |
Liquid polymeric compositions for controlled release of bioactive substances
|
DK1061948T3
(da)
|
1998-03-20 |
2003-03-31 |
Takeda Chemical Industries Ltd |
Præparat til vedvarende frigivelse af et fysiologisk aktivt polypeptid samt fremstilling deraf
|
US6284282B1
(en)
*
|
1998-04-29 |
2001-09-04 |
Genentech, Inc. |
Method of spray freeze drying proteins for pharmaceutical administration
|
EP3112468A1
(de)
|
1998-05-15 |
2017-01-04 |
Genentech, Inc. |
Il-17-homologe polypeptide und therapeutische verwendung davon
|
EP2333069A3
(de)
|
1998-05-15 |
2011-09-14 |
Genentech, Inc. |
Therapeutische verwendungen von il-17 homologe polypeptide
|
US20020172678A1
(en)
|
2000-06-23 |
2002-11-21 |
Napoleone Ferrara |
EG-VEGF nucleic acids and polypeptides and methods of use
|
US6696063B1
(en)
*
|
1998-12-30 |
2004-02-24 |
Applied Research Systems Ars Holding N.V. |
Treatment of HIV-associated dysmorphia/dysmetabolic syndrome (HADDS) with or without lipodystrophy
|
CA2363141C
(en)
|
1999-02-26 |
2010-04-06 |
Chiron Corporation |
Microemulsions with adsorbed macromolecules and microparticles
|
US6451347B1
(en)
*
|
1999-03-01 |
2002-09-17 |
Alkermes Controlled Therapeutics, Inc. |
Method for purifying human growth hormone
|
US7018654B2
(en)
*
|
1999-03-05 |
2006-03-28 |
New River Pharmaceuticals Inc. |
Pharmaceutical composition containing an active agent in an amino acid copolymer structure
|
US6716452B1
(en)
|
2000-08-22 |
2004-04-06 |
New River Pharmaceuticals Inc. |
Active agent delivery systems and methods for protecting and administering active agents
|
US6444223B1
(en)
|
1999-05-28 |
2002-09-03 |
Alkermes Controlled Therapeutics, Inc. |
Method of producing submicron particles of a labile agent and use thereof
|
EP1949890A3
(de)
|
1999-06-04 |
2011-05-18 |
ALZA Corporation |
Implantierbare Gelzusammensetzungen und Herstellungsverfahren dafür
|
RU2271196C2
(ru)
*
|
1999-06-04 |
2006-03-10 |
Элзэ Копэрейшн |
Имплантируемая композиция (варианты) и способ ее приготовления
|
US6586011B2
(en)
|
1999-06-10 |
2003-07-01 |
Southpac Trust International, Inc. |
Microencapsulated plasminogen activators
|
EP1956030B1
(de)
|
1999-06-15 |
2009-11-11 |
Genentech, Inc. |
Sekretierte und Transmembran-Polypeptide sowie Nukleinsäuren zu deren Kodierung
|
US7713739B1
(en)
|
2000-11-17 |
2010-05-11 |
Novartis Vaccines And Diagnostics, Inc. |
Microparticle-based transfection and activation of dendritic cells
|
US6310166B1
(en)
|
1999-08-12 |
2001-10-30 |
Closure Medical Corporation |
Sterilized cyanoacrylate solutions containing thickeners
|
FR2797784B1
(fr)
*
|
1999-08-27 |
2001-11-30 |
Mainelab |
Procede d'encapsulation de matieres actives par coacervation de polymeres en solvant organique non-chlore
|
DE60023324T2
(de)
*
|
1999-09-16 |
2006-07-20 |
Novo Nordisk A/S |
Zusammensetzung zur in-vitro befruchtung
|
AU7313400A
(en)
|
1999-09-17 |
2001-04-24 |
Takeda Chemical Industries Ltd. |
Process for producing protein powder
|
US6458387B1
(en)
*
|
1999-10-18 |
2002-10-01 |
Epic Therapeutics, Inc. |
Sustained release microspheres
|
US6284283B1
(en)
|
1999-10-21 |
2001-09-04 |
Alkermes Controlled Therapeutics, Inc. |
Method of producing sub-micron particles of biologically active agents and uses thereof
|
EP2228446A1
(de)
|
1999-12-01 |
2010-09-15 |
Genentech, Inc. |
Sekretierte und transmembrane Polypeptide, sowie dafür codierende Nukleinsäuren
|
US6743446B2
(en)
|
1999-12-15 |
2004-06-01 |
The Ohio State University Research Foundation |
Methods for stabilizing biologically active agents encapsulated in biodegradable controlled-release polymers
|
US20040071715A1
(en)
*
|
1999-12-15 |
2004-04-15 |
Schwendeman Steven P. |
Polymer compositions that stabilize and control the release of formaldehyde-treated vaccine antigens
|
EP2290081A3
(de)
|
1999-12-23 |
2012-08-01 |
Genentech, Inc. |
IL-17-homologe Polypeptide und ihre therapeutische Verwendung
|
EP1246917B1
(de)
*
|
2000-01-13 |
2009-03-04 |
Genentech, Inc. |
Menschliche stra6 polypeptide
|
US7029700B2
(en)
*
|
2000-01-14 |
2006-04-18 |
Brown University Research Foundation |
Micronized freeze-dried particles
|
US6821520B2
(en)
*
|
2000-02-15 |
2004-11-23 |
Allergan, Inc. |
Clostridial toxin therapy for Hashimoto's thyroiditis
|
US6358513B1
(en)
|
2000-02-15 |
2002-03-19 |
Allergan Sales, Inc. |
Method for treating Hashimoto's thyroiditis
|
US6773711B2
(en)
*
|
2000-02-15 |
2004-08-10 |
Allergan, Inc. |
Botulinum toxin therapy for Hashimoto's thyroiditis
|
US6524580B1
(en)
|
2000-02-15 |
2003-02-25 |
Allergan Sales, Inc. |
Method for treating thyroid disorders
|
US6319506B1
(en)
|
2000-02-22 |
2001-11-20 |
Allergan, Sales, Inc. |
Method for treating hypercalcemia
|
US20030211974A1
(en)
*
|
2000-03-21 |
2003-11-13 |
Brodbeck Kevin J. |
Gel composition and methods
|
US6740520B2
(en)
*
|
2000-03-21 |
2004-05-25 |
Genentech, Inc. |
Cytokine receptor and nucleic acids encoding the same
|
US20040086970A1
(en)
*
|
2000-03-22 |
2004-05-06 |
Genentech, Inc. |
Novel cytokine receptors and nucleic acids encoding the same
|
WO2001072323A2
(en)
*
|
2000-03-24 |
2001-10-04 |
Genentech, Inc. |
Use of insulin for the treatment of cartilagenous disorders
|
US6998137B2
(en)
*
|
2000-04-07 |
2006-02-14 |
Macromed, Inc. |
Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix
|
JP4361710B2
(ja)
|
2000-04-19 |
2009-11-11 |
ジェネンテック・インコーポレーテッド |
徐放製剤
|
US8404217B2
(en)
|
2000-05-10 |
2013-03-26 |
Novartis Ag |
Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
|
AU6124601A
(en)
|
2000-05-10 |
2001-11-20 |
Alliance Pharmaceutical Corporation |
Phospholipid-based powders for drug delivery
|
US7871598B1
(en)
|
2000-05-10 |
2011-01-18 |
Novartis Ag |
Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
|
US6264987B1
(en)
|
2000-05-19 |
2001-07-24 |
Alkermes Controlled Therapeutics Inc. Ii |
Method for preparing microparticles having a selected polymer molecular weight
|
US6495164B1
(en)
|
2000-05-25 |
2002-12-17 |
Alkermes Controlled Therapeutics, Inc. I |
Preparation of injectable suspensions having improved injectability
|
US20050214327A1
(en)
*
|
2000-06-02 |
2005-09-29 |
Allergan, Inc. |
Neurotoxin-containing suppositories and related methods
|
US20040170665A1
(en)
*
|
2000-06-02 |
2004-09-02 |
Allergan, Inc. |
Intravitreal botulinum toxin implant
|
AU6531101A
(en)
|
2000-06-02 |
2001-12-17 |
Genentech Inc |
Secreted and transmembrane polypeptides and nucleic acids encoding the same
|
US6306423B1
(en)
|
2000-06-02 |
2001-10-23 |
Allergan Sales, Inc. |
Neurotoxin implant
|
US20040033241A1
(en)
*
|
2000-06-02 |
2004-02-19 |
Allergan, Inc. |
Controlled release botulinum toxin system
|
KR100381382B1
(ko)
*
|
2000-06-28 |
2003-04-23 |
한국과학기술원 |
지속적 약물조절방출이 가능한 생분해성 미립담체 및 그의제조방법
|
US6719970B1
(en)
|
2000-07-10 |
2004-04-13 |
Alkermes Controlled Therapeutics, Inc. |
Method of generating cartilage
|
CA2418960A1
(en)
|
2000-08-07 |
2002-02-14 |
Inhale Therapeutic Systems, Inc. |
Inhaleable spray dried 4-helix bundle protein powders having minimized aggregation
|
US6296842B1
(en)
|
2000-08-10 |
2001-10-02 |
Alkermes Controlled Therapeutics, Inc. |
Process for the preparation of polymer-based sustained release compositions
|
US6479065B2
(en)
|
2000-08-10 |
2002-11-12 |
Alkermes Controlled Therapeutics, Inc. |
Process for the preparation of polymer-based sustained release compositions
|
WO2002013786A2
(en)
*
|
2000-08-15 |
2002-02-21 |
Board Of Trustees Of The University Of Illinois |
Method of forming microparticles
|
ATE412009T1
(de)
|
2000-08-24 |
2008-11-15 |
Genentech Inc |
Methode zur inhibierung von il-22 induziertem pap1
|
EP1944317A3
(de)
|
2000-09-01 |
2008-09-17 |
Genentech, Inc. |
Sekretierte und Transmembran-Polypeptide sowie Nukleinsäure zu deren Kodierung
|
US6824822B2
(en)
*
|
2001-08-31 |
2004-11-30 |
Alkermes Controlled Therapeutics Inc. Ii |
Residual solvent extraction method and microparticles produced thereby
|
US6471995B1
(en)
|
2000-09-27 |
2002-10-29 |
Alkermes Controlled Therapeutics, Inc. Ii |
Apparatus and method for preparing microparticles using liquid-liquid extraction
|
JP2004510730A
(ja)
|
2000-10-06 |
2004-04-08 |
ヤゴテック アーゲー |
非経口的投与可能な制御放出微粒子調製物
|
SE517422C2
(sv)
|
2000-10-06 |
2002-06-04 |
Bioglan Ab |
Farmaceutiskt acceptabel stärkelse
|
SE517421C2
(sv)
|
2000-10-06 |
2002-06-04 |
Bioglan Ab |
Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
|
US6673580B2
(en)
*
|
2000-10-27 |
2004-01-06 |
Genentech, Inc. |
Identification and modification of immunodominant epitopes in polypeptides
|
DE60138641D1
(de)
|
2000-10-27 |
2009-06-18 |
Baxter Healthcare Sa |
Herstellung von mikrokügelchen
|
US8394813B2
(en)
|
2000-11-14 |
2013-03-12 |
Shire Llc |
Active agent delivery systems and methods for protecting and administering active agents
|
SE518008C2
(sv)
*
|
2000-11-16 |
2002-08-13 |
Bioglan Ab |
Parenteralt administrerbara mikropartiklar och förfarande för framställning av desamma
|
SE518007C2
(sv)
|
2000-11-16 |
2002-08-13 |
Bioglan Ab |
Förfarande för framställning av mikropartiklar
|
US20020114843A1
(en)
*
|
2000-12-27 |
2002-08-22 |
Ramstack J. Michael |
Preparation of microparticles having improved flowability
|
US20070142325A1
(en)
*
|
2001-01-08 |
2007-06-21 |
Gustavsson Nils O |
Starch
|
US20040022861A1
(en)
*
|
2001-01-30 |
2004-02-05 |
Williams Robert O. |
Process for production of nanoparticles and microparticles by spray freezing into liquid
|
US7824700B2
(en)
*
|
2001-02-23 |
2010-11-02 |
Genentech, Inc. |
Erodible polymers for injection
|
FR2822834B1
(fr)
*
|
2001-04-02 |
2005-02-25 |
Flamel Tech Sa |
Suspension colloidale de nanoparticules a base de copolymeres amphiphile pour la vectorisation de principes actifs et leur mode de preparation
|
US6558702B2
(en)
*
|
2001-04-13 |
2003-05-06 |
Alkermes Controlled Therapeutics, Inc. |
Method of modifying the release profile of sustained release compositions
|
US20060269602A1
(en)
*
|
2001-04-13 |
2006-11-30 |
Dasch James R |
Method of modifying the release profile of sustained release compositions
|
US6887857B2
(en)
*
|
2001-04-27 |
2005-05-03 |
Scimed Life Systems, Inc. |
Microparticle protection of therapeutic agents
|
WO2002092619A2
(en)
|
2001-05-14 |
2002-11-21 |
The Gouvernment Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Modified growth hormone
|
US20070160576A1
(en)
|
2001-06-05 |
2007-07-12 |
Genentech, Inc. |
IL-17A/F heterologous polypeptides and therapeutic uses thereof
|
AU2002320122B2
(en)
|
2001-06-21 |
2007-07-26 |
Genentech, Inc. |
Sustained release formulation
|
ATE395042T1
(de)
*
|
2001-08-16 |
2008-05-15 |
Baxter Int |
Darreichungsformen welche mikropartikel und treibgas enthalten
|
US20080026068A1
(en)
*
|
2001-08-16 |
2008-01-31 |
Baxter Healthcare S.A. |
Pulmonary delivery of spherical insulin microparticles
|
US7169752B2
(en)
*
|
2003-09-30 |
2007-01-30 |
New River Pharmaceuticals Inc. |
Compounds and compositions for prevention of overdose of oxycodone
|
US20060014697A1
(en)
*
|
2001-08-22 |
2006-01-19 |
Travis Mickle |
Pharmaceutical compositions for prevention of overdose or abuse
|
US7105181B2
(en)
|
2001-10-05 |
2006-09-12 |
Jagotec, Ag |
Microparticles
|
EP1446104B2
(de)
*
|
2001-11-01 |
2011-08-03 |
Novartis AG |
Sprühtrocknungsverfahren
|
US20030170289A1
(en)
*
|
2001-11-14 |
2003-09-11 |
Guohua Chen |
Injectable depot compositions and uses thereof
|
KR20040058101A
(ko)
*
|
2001-11-14 |
2004-07-03 |
알자 코포레이션 |
카테터 주입가능한 데포 조성물 및 그의 용도
|
US20070196415A1
(en)
*
|
2002-11-14 |
2007-08-23 |
Guohua Chen |
Depot compositions with multiple drug release rate controls and uses thereof
|
JP2005514393A
(ja)
*
|
2001-12-19 |
2005-05-19 |
ネクター セラピューティクス |
アミノグリコシドの肺への供給
|
US7255874B1
(en)
|
2001-12-21 |
2007-08-14 |
Closure Medical Corporation |
Biocompatible polymers and adhesives: compositions, methods of making and uses related thereto
|
NZ535008A
(en)
*
|
2002-02-08 |
2005-09-30 |
Alkermes Inc |
Polymer-based compositions for sustained release
|
EP2110434A1
(de)
|
2002-02-25 |
2009-10-21 |
Genentech, Inc. |
Typ-1 Cytokine Rezeptor GLM-R
|
SE0201599D0
(sv)
|
2002-03-21 |
2002-05-30 |
Skyepharma Ab |
Microparticles
|
EP1497410A4
(de)
*
|
2002-04-01 |
2005-05-25 |
Peter K Law |
Zelltransplantation zur herzregenerierung
|
FR2840614B1
(fr)
|
2002-06-07 |
2004-08-27 |
Flamel Tech Sa |
Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
|
AR039729A1
(es)
|
2002-06-25 |
2005-03-09 |
Alza Corp |
Formulaciones de deposito de corta duracion
|
US20040001889A1
(en)
*
|
2002-06-25 |
2004-01-01 |
Guohua Chen |
Short duration depot formulations
|
FR2843117B1
(fr)
*
|
2002-07-30 |
2004-10-15 |
Flamel Tech Sa |
Polyaminoacides fonctionnalises par au moins un groupement hydrophobe et leurs applications notamment therapeutiques
|
ES2321505T3
(es)
*
|
2002-07-31 |
2009-06-08 |
Alza Corporation |
Composiciones de deposito de polimero multimodal inyectables y empleo de las mismas.
|
MXPA05001242A
(es)
*
|
2002-07-31 |
2005-06-08 |
Alza Corp |
Composiciones de deposito inyectable y usos de las mismas.
|
BR0315304A
(pt)
*
|
2002-11-06 |
2005-08-16 |
Alza Corp |
Formulações com depósito para liberação controlada
|
CA2512052C
(en)
*
|
2002-12-31 |
2016-06-21 |
Altus Pharmaceuticals Inc. |
Human growth hormone crystals and methods for preparing them
|
BRPI0403964B8
(pt)
|
2003-04-04 |
2021-05-25 |
Genentech Inc |
formulações líquidas estáveis, artigo manufaturado e uso dessas formulações para o tratamento de disfunção mediada por ige
|
DE10315538A1
(de)
*
|
2003-04-04 |
2004-10-21 |
Siemens Ag |
Teilchen mit einer Membran
|
EP1620072B1
(de)
*
|
2003-05-01 |
2008-03-26 |
LTT Bio-Pharma Co., Ltd. |
Zubereitungen mit verzögerter freigabe enthaltend zink, und herstellung derselben
|
FR2855521B1
(fr)
*
|
2003-05-28 |
2005-08-05 |
Flamel Tech Sa |
Polyaminoacides fonctionnalises par au moins un groupement h ydrophobe et leurs applications notamment therapeutiques.
|
US20070184084A1
(en)
*
|
2003-05-30 |
2007-08-09 |
Guohua Chen |
Implantable elastomeric caprolactone depot compositions and uses thereof
|
AU2004245022A1
(en)
*
|
2003-05-30 |
2004-12-16 |
Alza Corporation |
Implantable elastomeric depot compositions, uses thereof and method of manufacturing
|
EP2367008A3
(de)
|
2003-06-06 |
2014-12-24 |
Genentech, Inc. |
Modulierung der Interaktion zwischen HGF-beta-Kette und C-Met
|
SI1641822T1
(sl)
|
2003-07-08 |
2013-08-30 |
Genentech, Inc. |
IL-17 A/F heterologni polipeptidi in njihove terapevtske uporabe
|
SG135204A1
(en)
*
|
2003-07-18 |
2007-09-28 |
Baxter Int |
Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation
|
US20050142205A1
(en)
*
|
2003-07-18 |
2005-06-30 |
Julia Rashba-Step |
Methods for encapsulating small spherical particles prepared by controlled phase separation
|
US20070092452A1
(en)
*
|
2003-07-18 |
2007-04-26 |
Julia Rashba-Step |
Methods for fabrication, uses, compositions of inhalable spherical particles
|
EP1646354A4
(de)
*
|
2003-07-22 |
2010-03-17 |
Baxter Int |
Kleine kugelförmige teilchen von niedermolekularen organischen molekülen und herstellungs- und anwendungsverfahren dafür
|
WO2005020933A2
(en)
|
2003-09-02 |
2005-03-10 |
University Of South Florida |
Nanoparticles for drug-delivery
|
FR2860516B1
(fr)
*
|
2003-10-03 |
2006-01-13 |
Flamel Tech Sa |
Homopolyaminoacides telecheliques fonctionnalises par des groupements hydrophobes et leurs applications notamment therapeutiques
|
JP2007508250A
(ja)
*
|
2003-10-10 |
2007-04-05 |
ノボ ノルディスク アクティーゼルスカブ |
持続性放出製剤における長期作用性分子
|
US20050118206A1
(en)
*
|
2003-11-14 |
2005-06-02 |
Luk Andrew S. |
Surfactant-based gel as an injectable, sustained drug delivery vehicle
|
US20050281879A1
(en)
*
|
2003-11-14 |
2005-12-22 |
Guohua Chen |
Excipients in drug delivery vehicles
|
US20050106214A1
(en)
*
|
2003-11-14 |
2005-05-19 |
Guohua Chen |
Excipients in drug delivery vehicles
|
FR2862541B1
(fr)
*
|
2003-11-21 |
2007-04-20 |
Flamel Tech Sa |
Formulations pharmaceutiques pour la liberation prolongee d'interferons et leurs applications therapeutiques
|
FR2862535B1
(fr)
*
|
2003-11-21 |
2007-11-23 |
Flamel Tech Sa |
Formulations pharmaceutiques pour la liberation prolongee d'interleukines et leurs applications therapeutiques
|
FR2862536B1
(fr)
*
|
2003-11-21 |
2007-11-23 |
Flamel Tech Sa |
Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
|
US7309500B2
(en)
*
|
2003-12-04 |
2007-12-18 |
The Board Of Trustees Of The University Of Illinois |
Microparticles
|
CA2548282A1
(en)
|
2003-12-11 |
2005-06-30 |
Genentech, Inc. |
Methods and compositions for inhibiting c-met dimerization and activation
|
US7481997B1
(en)
|
2004-02-12 |
2009-01-27 |
Montana State University |
Snow mountain virus genome sequence, virus-like particles and methods of use
|
EP2289911A3
(de)
|
2004-03-30 |
2011-03-30 |
NsGene A/S |
Therapeutische Verwendung des Wachstumsfaktors nsg33
|
CN1968700A
(zh)
*
|
2004-04-15 |
2007-05-23 |
阿尔克姆斯有限公司 |
聚合物基的持续释放装置
|
CN1980974A
(zh)
*
|
2004-04-23 |
2007-06-13 |
安姆根有限公司 |
低分子量聚乳酸聚合物
|
US20050260272A1
(en)
*
|
2004-05-05 |
2005-11-24 |
Alkermes Controlled Therapeutics, Inc. |
Method of forming microparticles that include a bisphosphonate and a polymer
|
EP1765294B1
(de)
|
2004-05-12 |
2008-09-24 |
Baxter International Inc. |
Nukleinsäure-mikrokügelchen, ihre herstellung und abgabe
|
WO2005112893A1
(en)
|
2004-05-12 |
2005-12-01 |
Baxter International Inc. |
Microspheres comprising protein and showing injectability at high concentrations of said agent
|
US8728525B2
(en)
|
2004-05-12 |
2014-05-20 |
Baxter International Inc. |
Protein microspheres retaining pharmacokinetic and pharmacodynamic properties
|
WO2005112885A2
(en)
*
|
2004-05-12 |
2005-12-01 |
Baxter International Inc. |
Oligonucleotide-containing microspheres, their use for the manufacture of a medicament for treating diabetes type 1
|
US20090136552A1
(en)
*
|
2004-07-30 |
2009-05-28 |
Mette Gronborg |
Growth factors nsg28, nsg30, and nsg32
|
AU2005325213B2
(en)
|
2004-08-04 |
2010-10-07 |
Evonik Corporation |
Methods for manufacturing delivery devices and devices thereof
|
NZ553149A
(en)
*
|
2004-08-12 |
2010-01-29 |
Quest Pharmaceutical Services |
Use of inositol hexaphosphate or inositol hexasulphate to complex biologically active compounds for the preparation of controlled release pharmaceutical compositions
|
KR101150242B1
(ko)
|
2004-10-27 |
2012-06-13 |
유니버시티 오브 덴버 |
부신피질 자극 호르몬 유사체 및 관련 방법
|
US7748343B2
(en)
|
2004-11-22 |
2010-07-06 |
The Board Of Trustees Of The University Of Illinois |
Electrohydrodynamic spraying system
|
US11246913B2
(en)
|
2005-02-03 |
2022-02-15 |
Intarcia Therapeutics, Inc. |
Suspension formulation comprising an insulinotropic peptide
|
EP1861125A2
(de)
*
|
2005-03-23 |
2007-12-05 |
Nektar Therapeutics Al, Corporation |
Konjugate eines hgh-teils und peg-derivate
|
EP1885335A1
(de)
*
|
2005-04-27 |
2008-02-13 |
BAXTER INTERNATIONAL INC. (a Delaware corporation) |
Oberflächenmodifizierte mikroteilchen und verfahren zu ihrer bildung und verwendung
|
US20060271262A1
(en)
*
|
2005-05-24 |
2006-11-30 |
Mclain Harry P Iii |
Wireless agricultural network
|
US8389469B2
(en)
*
|
2005-06-06 |
2013-03-05 |
The Rockefeller University |
Bacteriophage lysins for Bacillus anthracis
|
US7858843B2
(en)
|
2005-06-06 |
2010-12-28 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
CA2607901C
(en)
|
2005-06-13 |
2016-08-16 |
Rigel Pharmaceuticals, Inc. |
Methods and compositions for treating degenerative bone disorders using a syk inhibitory 2,4-pyrimidinediamine
|
PT2314623E
(pt)
|
2005-06-21 |
2012-10-02 |
Xoma Technology Ltd |
Anticorpos de ligação a il-1β e os seus fragmentos
|
US20070015689A1
(en)
*
|
2005-06-23 |
2007-01-18 |
Alza Corporation |
Complexation of metal ions with polypeptides
|
US7582291B2
(en)
*
|
2005-06-30 |
2009-09-01 |
The Rockefeller University |
Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
|
AU2006280321A1
(en)
|
2005-08-15 |
2007-02-22 |
Genentech, Inc. |
Gene disruptions, compositions and methods relating thereto
|
US8362086B2
(en)
|
2005-08-19 |
2013-01-29 |
Merial Limited |
Long acting injectable formulations
|
CA2620903A1
(en)
|
2005-08-24 |
2007-03-01 |
The Rockefeller University |
Ply-gbs mutant lysins
|
AU2006335053A1
(en)
|
2005-11-21 |
2007-07-19 |
Genentech, Inc. |
Novel gene disruptions, compositions and methods relating thereto
|
US20080032343A1
(en)
|
2005-12-22 |
2008-02-07 |
Genentech, Inc. |
Recombinant Production of Heparin Binding Proteins
|
AU2006330833A1
(en)
*
|
2005-12-23 |
2007-07-05 |
Altus Pharmaceuticals Inc. |
Compositions comprising polycation-complexed protein crystals and methods of treatment using them
|
CA2638821A1
(en)
|
2006-02-17 |
2007-10-11 |
Genentech, Inc. |
Gene disruptons, compositions and methods relating thereto
|
EP2389948A1
(de)
|
2006-03-23 |
2011-11-30 |
Novartis AG |
Antitumorzellenantigen-Antikörper-Therapeutika
|
CA2648322C
(en)
|
2006-04-10 |
2017-11-28 |
Genentech, Inc. |
Disheveled pdz modulators
|
EP2082645A1
(de)
|
2006-04-19 |
2009-07-29 |
Genentech, Inc. |
Neuartige Genunterbrechungen, dazugehörige Zusammensetzungen und Verfahren in Zusammenhang damit
|
US20070281031A1
(en)
*
|
2006-06-01 |
2007-12-06 |
Guohan Yang |
Microparticles and methods for production thereof
|
MX2009001226A
(es)
|
2006-08-04 |
2009-03-20 |
Baxter Int |
Composicion basada en microesferas para prevenir y/o revertir la diabetes autoinmune de nuevo inicio.
|
KR101200728B1
(ko)
|
2006-08-09 |
2012-11-13 |
인타르시아 세라퓨틱스 인코포레이티드 |
삼투성 전달 시스템 및 피스톤 조립체
|
AU2007319577A1
(en)
*
|
2006-10-06 |
2008-05-22 |
Baxter Healthcare S.A. |
Microencapsules containing surface-modified microparticles and methods of forming and using the same
|
RU2554747C9
(ru)
|
2006-12-20 |
2015-10-20 |
Ксома (Сша) Ллс |
Способы лечения il-1бета-зависимых заболеваний
|
WO2008118712A1
(en)
*
|
2007-03-22 |
2008-10-02 |
Alkermes, Inc. |
Coacervation process
|
CN101686939B
(zh)
*
|
2007-04-17 |
2013-03-27 |
巴克斯特国际公司 |
用于肺部投送的核酸微粒
|
AU2008244523B2
(en)
|
2007-04-23 |
2012-02-16 |
Intarcia Therapeutics, Inc. |
Suspension formulations of insulinotropic peptides and uses thereof
|
US20080264641A1
(en)
*
|
2007-04-30 |
2008-10-30 |
Slabaugh Billy F |
Blending Fracturing Gel
|
US20080317865A1
(en)
*
|
2007-06-20 |
2008-12-25 |
Alkermes, Inc. |
Quench liquids and washing systems for production of microparticles
|
CN101361968B
(zh)
|
2007-08-06 |
2011-08-03 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗脂肪肝中的应用
|
KR100845009B1
(ko)
*
|
2007-08-07 |
2008-07-08 |
한국생명공학연구원 |
전하를 띠는 물질이 고착된 다공성 고분자 입자 및 그제조방법
|
KR20100058541A
(ko)
*
|
2007-08-15 |
2010-06-03 |
아뮤닉스 인코포레이티드 |
생물학적 활성 폴리펩티드의 특성을 변경하기 위한 조성물 및 방법
|
US20090061009A1
(en)
*
|
2007-08-29 |
2009-03-05 |
Joseph Schwarz |
Composition and Method of Treatment of Bacterial Infections
|
PT2391650E
(pt)
|
2007-12-20 |
2015-01-14 |
Xoma Us Llc |
Métodos para o tratamento de gota
|
ES2718612T3
(es)
|
2007-12-20 |
2019-07-03 |
Evonik Corp |
Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
|
EP2240155B1
(de)
|
2008-02-13 |
2012-06-06 |
Intarcia Therapeutics, Inc |
Vorrichtungen, formulierungen und verfahren zur freisetzung mehrerer wirkstoffe
|
US9107815B2
(en)
|
2008-02-22 |
2015-08-18 |
Allergan, Inc. |
Sustained release poloxamer containing pharmaceutical compositions
|
US20110182946A1
(en)
*
|
2008-03-17 |
2011-07-28 |
Board Of Regents, The University Of Texas System |
Formation of Nanostructured Particles of Poorly Water Soluble Drugs and Recovery by Mechanical Techniques
|
MX2011000629A
(es)
|
2008-07-17 |
2011-04-26 |
Merial Ltd |
Formulaciones analgesicas inyectables de larga duracion para animales.
|
US8367427B2
(en)
|
2008-08-20 |
2013-02-05 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
US20100047292A1
(en)
*
|
2008-08-20 |
2010-02-25 |
Baxter International Inc. |
Methods of processing microparticles and compositions produced thereby
|
US8323615B2
(en)
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing multi-phasic dispersions
|
US8323685B2
(en)
*
|
2008-08-20 |
2012-12-04 |
Baxter International Inc. |
Methods of processing compositions containing microparticles
|
CA2749993C
(en)
*
|
2009-01-23 |
2016-12-20 |
Surmodics Pharmaceuticals, Inc. |
Continuous double emulsion process for making microparticles
|
US8703717B2
(en)
*
|
2009-02-03 |
2014-04-22 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
US8680050B2
(en)
*
|
2009-02-03 |
2014-03-25 |
Amunix Operating Inc. |
Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same
|
CN116925238A
(zh)
|
2009-02-03 |
2023-10-24 |
阿穆尼克斯制药公司 |
延伸重组多肽和包含该延伸重组多肽的组合物
|
JP5727459B2
(ja)
|
2009-04-22 |
2015-06-03 |
アルテオゼン, インクAlteogen, Inc |
体内持続性を維持することにより体内半減期が増加したタンパク質またはペプチド融合体
|
US9849188B2
(en)
|
2009-06-08 |
2017-12-26 |
Amunix Operating Inc. |
Growth hormone polypeptides and methods of making and using same
|
SI2462246T1
(en)
|
2009-09-28 |
2018-01-31 |
Intarcia Therapeutics, Inc. |
Fast-setting and / or cessation of substantially unchanged delivery of the product
|
US8535912B2
(en)
*
|
2009-10-15 |
2013-09-17 |
Genentech, Inc. |
Chimeric fibroblast growth factors with altered receptor specificity
|
WO2011056561A1
(en)
|
2009-10-27 |
2011-05-12 |
Beth Israel Deaconess Medical Center |
Methods and compositions for the generation and use of conformation-specific antibodies
|
US8637637B2
(en)
*
|
2010-01-12 |
2014-01-28 |
Bill Nai-Chau Sun |
Fc fusion proteins of human growth hormone
|
EP2523672B1
(de)
|
2010-01-15 |
2016-07-13 |
Rutgers, the State University of New Jersey |
Verwendung von vanadiumverbindungen für beschleunigte knochenheilung
|
PL2550018T3
(pl)
|
2010-03-22 |
2019-08-30 |
F.Hoffmann-La Roche Ag |
Kompozycje i sposoby użyteczne do stabilizowania preparatów zawierających białko
|
EP2566510A1
(de)
|
2010-05-03 |
2013-03-13 |
F. Hoffmann-La Roche AG |
Zusammensetzungen und verfahren zur reduzierung der viskosität von proteinhaltigen formulierungen
|
CA2802756C
(en)
|
2010-06-24 |
2021-05-04 |
Genentech, Inc. |
Compositions and methods for stabilizing protein-containing formulations
|
CN102380091A
(zh)
|
2010-08-31 |
2012-03-21 |
健能隆医药技术(上海)有限公司 |
白介素-22在治疗病毒性肝炎中的应用
|
CN103269708A
(zh)
|
2010-10-01 |
2013-08-28 |
Ns基因公司 |
镍纹蛋白用于治疗异常性疼痛、痛觉过敏、自发性疼痛和幻痛的用途
|
US9345765B2
(en)
|
2010-10-08 |
2016-05-24 |
Shanghai Kexin Biotech Co., Ltd. |
Diagnostic and therapeutic uses of moesin fragments
|
JP6080763B2
(ja)
|
2010-10-08 |
2017-02-15 |
シャンハイ クーシン バイオテック カンパニー,リミテッド |
モエシンモジュレーターおよびその使用
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
US20120208755A1
(en)
|
2011-02-16 |
2012-08-16 |
Intarcia Therapeutics, Inc. |
Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
|
WO2012149334A2
(en)
|
2011-04-27 |
2012-11-01 |
Beth Israel Deaconess Medical Center, Inc. |
Methods and compositions for the generation and use of conformation-specific antibodies
|
MX363226B
(es)
|
2011-10-31 |
2019-03-15 |
Genentech Inc |
Formulaciones de anticuerpos.
|
US20150017157A1
(en)
|
2011-12-19 |
2015-01-15 |
Xoma (Us) Llc |
Methods for treating acne
|
WO2013106489A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
WO2013106485A2
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Ultralong complementarity determining regions and uses thereof
|
WO2013168167A1
(en)
|
2012-05-10 |
2013-11-14 |
Painreform Ltd. |
Depot formulations of a hydrophobic active ingredient and methods for preparation thereof
|
CN105283196B
(zh)
|
2013-03-15 |
2018-10-12 |
贝丝以色列女执事医疗中心 |
用于产生和使用构象-特异性抗体的方法和组合物
|
CN105814074B
(zh)
|
2013-07-18 |
2020-04-21 |
图鲁斯生物科学有限责任公司 |
具有超长互补决定区的人源化抗体
|
EP3022224A2
(de)
|
2013-07-18 |
2016-05-25 |
Fabrus, Inc. |
Antikörper mit ultralangen komplementaritätsbestimmenden regionen
|
WO2015038938A1
(en)
|
2013-09-13 |
2015-03-19 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
KR102339240B1
(ko)
|
2013-10-15 |
2021-12-15 |
더 스크립스 리서치 인스티튜트 |
펩타이드 키메라 항원 수용체 t 세포 스위치 및 이의 용도
|
US20150238631A1
(en)
|
2013-10-15 |
2015-08-27 |
The California Institute For Biomedical Research |
Chimeric antigen receptor t cell switches and uses thereof
|
CN104623637A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
Il-22二聚体在制备静脉注射药物中的应用
|
CN104623639A
(zh)
|
2013-11-07 |
2015-05-20 |
健能隆医药技术(上海)有限公司 |
白介素22二聚体在制备治疗胰腺炎药物中的应用
|
EP3079668A1
(de)
|
2013-12-09 |
2016-10-19 |
Durect Corporation |
Pharmazeutisch aktive wirkstoffkomplexe, polymerkomplexe und zusammensetzungen und verfahren damit
|
EP4212180A1
(de)
|
2013-12-18 |
2023-07-19 |
The Scripps Research Institute |
Modifizierte therapeutika, geklammerte peptidlipidkonjugate und zusammensetzungen davon
|
US9889085B1
(en)
|
2014-09-30 |
2018-02-13 |
Intarcia Therapeutics, Inc. |
Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
|
NL2014230B1
(en)
|
2015-02-04 |
2016-10-12 |
Stichting Vu-Vumc |
Wound healing formulation.
|
MA41629A
(fr)
|
2015-03-04 |
2018-01-09 |
Center For Human Reproduction |
Compositions et méthodes d'utilisation de l'hormone anti-müllérienne pour le traitement de l'infertilité
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
US11091546B2
(en)
|
2015-04-15 |
2021-08-17 |
The Scripps Research Institute |
Optimized PNE-based chimeric receptor T cell switches and uses thereof
|
KR20240042548A
(ko)
|
2015-06-03 |
2024-04-02 |
인타르시아 세라퓨틱스 인코포레이티드 |
임플란트 배치 및 제거 시스템들
|
CN107921098A
(zh)
|
2015-06-17 |
2018-04-17 |
加州生物医学研究所 |
修饰的治疗剂及其组合物
|
CN109328069B
(zh)
|
2016-04-15 |
2023-09-01 |
亿一生物医药开发(上海)有限公司 |
Il-22在治疗坏死性小肠结肠炎中的用途
|
MA53353A
(fr)
|
2016-05-16 |
2021-06-09 |
Intarcia Therapeutics Inc |
Polypeptides sélectifs pour le récepteur du glucagon et méthodes pour leur utilisation
|
USD840030S1
(en)
|
2016-06-02 |
2019-02-05 |
Intarcia Therapeutics, Inc. |
Implant placement guide
|
USD860451S1
(en)
|
2016-06-02 |
2019-09-17 |
Intarcia Therapeutics, Inc. |
Implant removal tool
|
AU2017345479B2
(en)
|
2016-10-19 |
2024-03-21 |
The Scripps Research Institute |
Chimeric antigen receptor effector cell switches with humanized targeting moieties and/or optimized chimeric antigen receptor interacting domains and uses thereof
|
EP3565580B1
(de)
|
2017-01-03 |
2024-03-06 |
i2o Therapeutics, Inc. |
Kontinuierlicher verabreichung von exenatid und co-verabreichung von acetaminophen, ethinylestradiol oder levonorgestrel
|
KR20210145152A
(ko)
|
2019-04-01 |
2021-12-01 |
제넨테크, 인크. |
단백질-함유 제제들의 안정화를 위한 조성물들 및 방법들
|
EP4013788A1
(de)
|
2019-08-12 |
2022-06-22 |
Purinomia Biotech, Inc. |
Verfahren und zusammensetzungen zur förderung und verstärkung von t-zell-vermittelten immunantworten durch adcc-targeting von cd39-exprimierenden zellen
|
AU2020371784A1
(en)
|
2019-10-24 |
2022-06-02 |
Minotaur Therapeutics, Inc. |
Chimeric cytokine modified antibodies and methods of use thereof
|
CN115666621A
(zh)
|
2020-01-13 |
2023-01-31 |
度勒科特公司 |
具有减少的杂质的持续释放药物递送系统及相关方法
|
WO2022232321A1
(en)
|
2021-04-28 |
2022-11-03 |
Minotaur Therapeutics, Inc. |
Humanized chimeric bovine antibodies and methods of use
|
KR20240006581A
(ko)
|
2021-05-06 |
2024-01-15 |
호바 세라퓨틱스 에이피에스 |
화학요법-유도된 신경병성 통증의 예방 및 치료
|
WO2023104960A1
(en)
|
2021-12-10 |
2023-06-15 |
Hoba Therapeutics Aps |
Treatment of nociceptive pain
|