DE69327628D1 - Transdermales arzneimittelverabreichungssystem - Google Patents

Transdermales arzneimittelverabreichungssystem

Info

Publication number
DE69327628D1
DE69327628D1 DE69327628T DE69327628T DE69327628D1 DE 69327628 D1 DE69327628 D1 DE 69327628D1 DE 69327628 T DE69327628 T DE 69327628T DE 69327628 T DE69327628 T DE 69327628T DE 69327628 D1 DE69327628 D1 DE 69327628D1
Authority
DE
Germany
Prior art keywords
permeable membrane
gel layer
medicament
disposed
reservoirs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69327628T
Other languages
English (en)
Inventor
Angelo Joseph D
Henry Schur
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69327628D1 publication Critical patent/DE69327628D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69327628T 1992-04-08 1993-03-26 Transdermales arzneimittelverabreichungssystem Expired - Lifetime DE69327628D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86530992A 1992-04-08 1992-04-08
US07/927,837 US5756117A (en) 1992-04-08 1992-08-10 Multidose transdermal drug delivery system
PCT/US1993/003088 WO1993020787A1 (en) 1992-04-08 1993-03-26 Transdermal drug delivery system

Publications (1)

Publication Number Publication Date
DE69327628D1 true DE69327628D1 (de) 2000-02-24

Family

ID=27127889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327628T Expired - Lifetime DE69327628D1 (de) 1992-04-08 1993-03-26 Transdermales arzneimittelverabreichungssystem

Country Status (8)

Country Link
US (4) US5756117A (de)
EP (1) EP0593746B1 (de)
JP (1) JPH06508379A (de)
AT (1) ATE188866T1 (de)
AU (1) AU4045993A (de)
CA (1) CA2110903A1 (de)
DE (1) DE69327628D1 (de)
WO (1) WO1993020787A1 (de)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048337A (en) * 1992-01-07 2000-04-11 Principal Ab Transdermal perfusion of fluids
DE4326931A1 (de) * 1993-08-11 1995-02-16 Hoechst Ag Vorrichtung zum Entnehmen von festen Arzneiformen aus Blisterverpackungen
DE69413249T2 (de) * 1993-12-07 1999-05-06 Svedman Paul Vorrichtung zum gebrauch bei transdermischen infusionen
US5466465A (en) * 1993-12-30 1995-11-14 Harrogate Holdings, Limited Transdermal drug delivery system
DE4400769C2 (de) * 1994-01-13 1996-07-18 Lohmann Therapie Syst Lts Verfahren und Vorrichtung zur Herstellung einer flächigen Darreichungsform mit einer Arzneimittelwirkstoffe enthaltenden Zubereitung
DK0783301T3 (da) * 1994-09-30 1999-08-02 Becton Dickinson Co Fremgangsmåde til udformning og pakning af iontoforetiske medikamentleveringsplastre og lignende med henblik på forøgelse a
US5730721A (en) 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
SE9601528D0 (sv) * 1996-04-23 1996-04-23 Pharmacia Ab Transdermally administered dextromethorphan as antitissue agent
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US20060002949A1 (en) * 1996-11-14 2006-01-05 Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. Transcutaneous immunization without heterologous adjuvant
US6797276B1 (en) 1996-11-14 2004-09-28 The United States Of America As Represented By The Secretary Of The Army Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
US5980898A (en) * 1996-11-14 1999-11-09 The United States Of America As Represented By The U.S. Army Medical Research & Material Command Adjuvant for transcutaneous immunization
US20060002959A1 (en) * 1996-11-14 2006-01-05 Government Of The United States Skin-sctive adjuvants for transcutaneous immuization
CA2291335A1 (en) 1997-05-27 1998-12-03 Algos Pharmaceutical Corporation Analgesic drug composition containing a capsaicinoid and potentiator therefor
US20040258703A1 (en) * 1997-11-14 2004-12-23 The Government Of The Us, As Represented By The Secretary Of The Army Skin-active adjuvants for transcutaneous immunization
TW406018B (en) * 1998-05-21 2000-09-21 Elan Corp Plc Improved adhesive system for medical devices
DE69902391T2 (de) 1998-06-24 2003-03-06 Transderm Technologies Llc San Nichtinvasiven transdermal detektion von analyten
DE19850517B4 (de) * 1998-11-03 2004-02-12 Lts Lohmann Therapie-Systeme Ag Verwendung eines wirkstoffhaltigen transdermalen therapeutischen Systems in einer Kombinationsbehandlung mit und ohne Ultraschall
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US6283956B1 (en) 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US6887260B1 (en) 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US20060212025A1 (en) 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6794536B1 (en) 1998-12-10 2004-09-21 Aesqen, Inc. Method for preparation of disodium pamidronate
US6160165A (en) * 1998-12-10 2000-12-12 Aesgen, Inc. Method for preparation of disodium pamidronate
JP4932086B2 (ja) * 1999-04-08 2012-05-16 インターセル ユーエスエイ、インコーポレイテッド 経皮的免疫のための乾燥製剤
DE60018582T2 (de) * 1999-08-18 2006-01-19 Microchips, Inc., Bedford Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien
US6221384B1 (en) * 1999-11-05 2001-04-24 Anthony C. Pagedas Segmented transdermal dosage unit
US6808522B2 (en) * 1999-12-10 2004-10-26 Massachusetts Institute Of Technology Microchip devices for delivery of molecules and methods of fabrication thereof
US6607739B1 (en) * 2000-02-14 2003-08-19 Johnson & Johnson Consumer Companies, Inc. Dispensing article
ATE499988T1 (de) 2000-03-02 2011-03-15 Microchips Inc Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien
WO2001091902A2 (en) 2000-05-30 2001-12-06 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
DE60116520T2 (de) * 2000-10-10 2006-08-31 Microchips, Inc., Bedford Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
AU2002224453A1 (en) 2000-10-11 2002-04-22 Microchips, Inc. Microchip reservoir devices and facilitated corrosion of electrodes
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
JP4657577B2 (ja) * 2001-01-09 2011-03-23 マイクロチップス・インコーポレーテッド 眼への適用および他への適用のための可撓性マイクロチップデバイス
WO2002064162A2 (en) * 2001-02-13 2002-08-22 Government Of The United States, As Represented By The Secretary Of The Army Vaccine for transcutaneous immunization
CN1516595A (zh) * 2001-03-19 2004-07-28 Iomai公司 用于经皮免疫的贴剂
JP2004536631A (ja) * 2001-05-03 2004-12-09 マサチューセッツ・アイ・アンド・イア・インファーマリー 移植可能な薬物送達デバイスおよびその使用
CA2372450A1 (en) * 2001-05-10 2001-09-19 Pharmaceutical Partners Of Canada Inc. Liquid injectable formulation of disodium pamidronate
WO2002099457A1 (en) * 2001-05-31 2002-12-12 Massachusetts Inst Technology Microchip devices with improved reservoir opening
EP1399135B1 (de) * 2001-06-28 2004-12-29 Microchips, Inc. Verfahren zum hermetischen versiegeln von mikrochip-reservoir-vorrichtungen
US20040137039A1 (en) * 2002-07-22 2004-07-15 Trustees Of Stevens Institute Of Technology Methods for controlled release of molecules from layered polymer films
US20050008828A1 (en) * 2002-07-25 2005-01-13 Trustees Of Stevens Institute Of Technology Patterned polymer microgel and method of forming same
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
JP4436258B2 (ja) * 2002-08-16 2010-03-24 マイクロチップス・インコーポレーテッド 制御された放出デバイスおよび方法
US7326421B2 (en) 2002-10-21 2008-02-05 Kensey Nash Corporation Device and methods for sequential, regional delivery of multiple cytotoxic agents and directed assembly of wound repair tissues
CA2531099A1 (en) 2003-04-10 2004-10-28 Light Bioscience, Llc Photomodulation methods and devices for regulating cell proliferation and gene expression
US20060246104A1 (en) * 2003-04-16 2006-11-02 Massia Stephen P Stable rgd peptidomimetic composition
US8790689B2 (en) * 2003-04-30 2014-07-29 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US8778382B2 (en) * 2003-04-30 2014-07-15 Purdue Pharma L.P. Tamper resistant transdermal dosage form
US7182955B2 (en) * 2003-04-30 2007-02-27 3M Innovative Properties Company Abuse-resistant transdermal dosage form
US20040219195A1 (en) * 2003-04-30 2004-11-04 3M Innovative Properties Company Abuse-resistant transdermal dosage form
WO2005007020A2 (en) * 2003-07-03 2005-01-27 Corium International, Inc. Wound dressing, ingredient delivery device and iv hold-down, and method relating to same
US20060014003A1 (en) * 2003-07-24 2006-01-19 Libera Matthew R Functional nano-scale gels
CA2533129A1 (en) 2003-07-31 2005-02-10 Light Bioscience, Llc System and method for the photodynamic treatment of burns, wounds, and related skin disorders
US8524272B2 (en) 2003-08-15 2013-09-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer
US7470266B2 (en) * 2003-09-16 2008-12-30 I-Flow Corporation Fluid medication delivery device
US20050163714A1 (en) * 2003-10-02 2005-07-28 Sukhishvili Svetlana A. Capsules of multilayered neutral polymer films associated by hydrogen bonding
CA2544291C (en) * 2003-10-27 2013-01-08 University Of Basel Transdermal drug delivery method and system
EP1694200B1 (de) * 2003-11-03 2010-09-29 MicroCHIPS, Inc. Medizinprodukt zum messen von glucose
ES2334681T3 (es) * 2004-03-19 2010-03-15 Mcneil Ab Medios para la administracion transdermica de nicotina.
WO2005094526A2 (en) * 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
US20100260669A1 (en) * 2004-05-13 2010-10-14 Anthony Joonkyoo Yun Treatment of Seasonal Conditions Through Modulation of the Autonomic Nervous System
US7899527B2 (en) * 2004-05-13 2011-03-01 Palo Alto Investors Treatment of conditions through modulation of the autonomic nervous system during at least one predetermined menstrual cycle phase
US7537590B2 (en) * 2004-07-30 2009-05-26 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
AU2005325213B2 (en) * 2004-08-04 2010-10-07 Evonik Corporation Methods for manufacturing delivery devices and devices thereof
WO2006023644A2 (en) * 2004-08-20 2006-03-02 3M Innovative Properties Company Transdermal drug delivery device with translucent protective film
ATE424928T1 (de) * 2004-09-01 2009-03-15 Microchips Inc Behältervorrichtungen mit mehreren verschlüssen zur gesteuerten abgabe oder exponierung des behälterinhalts
US8252321B2 (en) * 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
EP1802258A4 (de) * 2004-09-13 2015-09-23 Chrono Therapeutics Inc Biosynchrone transdermale arzneiabgabe
DE102004045599A1 (de) * 2004-09-17 2006-03-23 Grünenthal GmbH System zur sequentiellen, transdermalen Verabreichung von systemisch wirksamen Substanzen
US20060088581A1 (en) * 2004-09-22 2006-04-27 Thomas Blaszczykiewicz Device for delivery of therapeutic agent
US8252319B2 (en) 2004-10-21 2012-08-28 Durect Corporation Transdermal delivery system for sufentanil
SI1814531T1 (sl) 2004-10-21 2010-10-29 Durect Corp Transdermalni dostavni sistem
US7413846B2 (en) * 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
DK1836665T3 (da) * 2004-11-19 2013-04-15 Glaxosmithkline Llc Fremgangsmåde til specialtilpasset afgivelse af medikamentkombinationsprodukter med variabel dosis til individualisering af terapier
US20080076975A1 (en) * 2005-01-25 2008-03-27 Microchips, Inc. Method and implantable device with reservoir array for pre-clinical in vivo testing
US20060223786A1 (en) * 2005-04-01 2006-10-05 Smith David J Transdermal pain control method and device
WO2006127905A2 (en) 2005-05-24 2006-11-30 Chrono Therapeutics, Inc. Portable drug delivery device
US20080221556A1 (en) * 2005-07-05 2008-09-11 Koninklijke Philips Electronics, N.V. Device For the Controlled Release of a Predefined Quantity of a Substance
US20070248657A1 (en) * 2006-04-25 2007-10-25 Smith David J Multi-compartment transdermal pain control device
US20080008747A1 (en) * 2006-07-07 2008-01-10 Royds Robert B Transdermal patch
US20110150766A1 (en) * 2006-07-07 2011-06-23 Royds Robert B Transdermal patch with fatal overdose protection
WO2008091602A2 (en) * 2007-01-22 2008-07-31 Corium International, Inc. Applicators for microneedle arrays
US20100178319A1 (en) * 2007-03-27 2010-07-15 Lars Lindgren Topical Dermal Delivery Device For Nitric Oxide Delivery
US8093039B2 (en) * 2007-04-10 2012-01-10 The Trustees Of The Stevens Institute Of Technology Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
WO2008130587A2 (en) 2007-04-16 2008-10-30 Corium International, Inc. Solvent-cast microneedle arrays containing active
US20080286348A1 (en) * 2007-05-16 2008-11-20 Todhunter John A Secured transdermal delivery system
NZ582565A (en) 2007-07-10 2012-07-27 Agile Therapeutics Inc Dermal delivery device with in situ seal
ATE485797T1 (de) * 2007-08-21 2010-11-15 Lohmann Therapie Syst Lts Verfahren zum mehrspurigen konfektionieren transdermaler therapeutischer pflaster
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
ES2718612T3 (es) 2007-12-20 2019-07-03 Evonik Corp Procedimiento para preparar micropartículas que tienen un bajo volumen de disolvente residual
US20100221313A1 (en) * 2008-12-01 2010-09-02 Innovative Pharmaceuticals, Llc Transdermal reservoir patch
EP2429627B1 (de) * 2009-04-24 2017-06-14 Corium International, Inc. Verfahren zur herstellung von mikroprojektionsarrays
US8523791B2 (en) * 2009-08-11 2013-09-03 Laboratoire Naturel Paris, Llc Multi-modal drug delivery system
US20140200529A1 (en) * 2009-08-27 2014-07-17 Julie Hyde-Edwards Post-nipple reconstruction protector
EP2552407A1 (de) 2010-03-31 2013-02-06 Wockhardt Limited Zusammensetzung mit insulin und kräuteröl für transdermale oder transmukosale verabreichung
AU2011248108B2 (en) 2010-05-04 2016-05-26 Corium Pharma Solutions, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
CA2841785A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US20130090633A1 (en) * 2011-10-07 2013-04-11 University Of Southern California Osmotic patch pump
WO2013103514A1 (en) 2012-01-04 2013-07-11 The Trustees Of The Stevens Institute Of Technology Clay-containing thin films as carriers of absorbed molecules
US9314571B1 (en) * 2012-02-10 2016-04-19 Mphase Technologies, Inc. Drug delivery system
CN105073178B (zh) 2012-12-21 2019-07-30 考里安国际公司 用于治疗剂递送的微阵列及其使用方法
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
WO2014164314A1 (en) 2013-03-12 2014-10-09 Corium International, Inc. Microprojection applicators
JP2016512754A (ja) 2013-03-15 2016-05-09 コリウム インターナショナル， インコーポレイテッド 治療剤の送達のためのマイクロアレイ、使用方法および製造方法
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
EP2968118B1 (de) 2013-03-15 2022-02-09 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur verwendung
EP2968116A1 (de) 2013-03-15 2016-01-20 Corium International, Inc. Mikroarray mit polymerfreien mikrostrukturen, verfahren zur herstellung und verfahren zur verwendung
US10610416B2 (en) 2013-03-15 2020-04-07 Adaco Innovations, Llc System, method, and product for an adhesive strip configured to selectively dispense a fluid
GB2521334B (en) * 2013-08-21 2018-06-20 Univ Swansea Topical drug patch including microspheres
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
US10679516B2 (en) 2015-03-12 2020-06-09 Morningside Venture Investments Limited Craving input and support system
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
WO2017184104A1 (en) * 2016-04-18 2017-10-26 Mphase Technologies, Inc. Drug delivery system
WO2018129304A1 (en) 2017-01-06 2018-07-12 Chrono Therapeutics Inc. Transdermal drug delivery devices and methods
EP3447558A1 (de) * 2017-08-23 2019-02-27 Sterlite Technologies Limited Glasfaserbandkanalkabel
EP3801732A4 (de) 2018-05-29 2022-04-27 Morningside Venture Investments Limited Verfahren und systeme zur wirkstofffreisetzung

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3405070A (en) * 1961-01-30 1968-10-08 Ibm Process for preparation of microcapsules
BE622026A (de) * 1961-09-05
US3270100A (en) * 1962-08-01 1966-08-30 Delvan Mfg Company Method for making capsules by interfacial polymerization
DE1249823B (de) * 1964-01-15 1967-09-14
US3396117A (en) * 1965-09-07 1968-08-06 Amp Inc Encapsulation technique
US3341466A (en) * 1966-10-31 1967-09-12 Brynko Carl Process for making capsules
US3567650A (en) * 1969-02-14 1971-03-02 Ncr Co Method of making microscopic capsules
US3797494A (en) * 1969-04-01 1974-03-19 Alza Corp Bandage for the administration of drug by controlled metering through microporous materials
US3875074A (en) * 1972-03-06 1975-04-01 Champion Int Corp Formation of microcapsules by interfacial cross-linking of emulsifier, and microcapsules produced thereby
US4145184A (en) * 1975-11-28 1979-03-20 The Procter & Gamble Company Detergent composition containing encapsulated perfume
US4277364A (en) * 1975-12-22 1981-07-07 The United States Of America As Represented By The Secretary Of Agriculture Encapsulation by entrapment
US4207315A (en) * 1976-10-20 1980-06-10 University Patents, Inc. Process for treating proliferative skin diseases using certain diamino compounds
US4391909A (en) * 1979-03-28 1983-07-05 Damon Corporation Microcapsules containing viable tissue cells
US4460368A (en) * 1981-10-29 1984-07-17 Almedco, Inc. Trans-dermal medication system
US4422970A (en) * 1982-05-20 1983-12-27 Nelson Research & Development Company Method of synthesis of 1-dodecylazacycloheptan-2-one
US4806355A (en) * 1983-06-06 1989-02-21 Connaught Laboratories Limited Microencapsulation of living tissue and cells
US4708716A (en) * 1983-08-18 1987-11-24 Drug Delivery Systems Inc. Transdermal drug applicator
US4573996A (en) * 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
US4834978A (en) * 1984-10-01 1989-05-30 Biotek, Inc. Method of transdermal drug delivery
US4904475A (en) * 1985-05-03 1990-02-27 Alza Corporation Transdermal delivery of drugs from an aqueous reservoir
DE3528293A1 (de) * 1985-08-07 1987-02-19 Holtsch Maria Metallwaren Zaehl- und anzeigegeraet zur einnahme von medikamenten
US4666441A (en) * 1985-12-17 1987-05-19 Ciba-Geigy Corporation Multicompartmentalized transdermal patches
US4743249A (en) * 1986-02-14 1988-05-10 Ciba-Geigy Corp. Dermal and transdermal patches having a discontinuous pattern adhesive layer
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US4917676A (en) * 1986-11-20 1990-04-17 Ciba-Geigy Corporation User-activated transdermal therapeutic system
US4917688A (en) * 1987-01-14 1990-04-17 Nelson Research & Development Co. Bandage for transdermal delivery of systemically-active drug
US5071656A (en) * 1987-03-05 1991-12-10 Alza Corporation Delayed onset transdermal delivery device
CH674618A5 (de) * 1987-04-02 1990-06-29 Ciba Geigy Ag
US5064654A (en) * 1989-01-11 1991-11-12 Ciba-Geigy Corporation Mixed solvent mutually enhanced transdermal therapeutic system
ES2062093T3 (es) * 1988-08-02 1994-12-16 Ciba Geigy Ag Emplasto de varias capas.
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US4998623A (en) * 1990-04-27 1991-03-12 Omni Medical Systems Inc. Medication dispensing package
US5071704A (en) * 1990-06-13 1991-12-10 Fischel Ghodsian Fariba Device for controlled release of vapors and scents
US5064422A (en) * 1990-10-18 1991-11-12 Bertek, Inc. Twin patch applicator

Also Published As

Publication number Publication date
EP0593746B1 (de) 2000-01-19
ATE188866T1 (de) 2000-02-15
JPH06508379A (ja) 1994-09-22
AU4045993A (en) 1993-11-18
US5505957A (en) 1996-04-09
CA2110903A1 (en) 1993-10-28
EP0593746A4 (de) 1995-08-09
WO1993020787A1 (en) 1993-10-28
US5932240A (en) 1999-08-03
US5756117A (en) 1998-05-26
US5336213A (en) 1994-08-09
EP0593746A1 (de) 1994-04-27

Similar Documents

Publication Publication Date Title
DE69327628D1 (de) Transdermales arzneimittelverabreichungssystem
GR3029308T3 (en) Medical device for the administration of active ingredients or drugs at very low doses, particularly homeopathic drugs.
US4698062A (en) Medical device for pulsatile transdermal delivery of biologically active agents
US4060084A (en) Method and therapeutic system for providing chemotherapy transdermally
ZA895858B (en) Multilayer plaster
DE69121881D1 (de) Hautelektrodenaufbau und dazugehöriges gerät zur transdermalen verabreichung von heilmitteln
NO923769D0 (no) System for iontoforetisk tilfoersel av et medikament
KR890701164A (ko) 피부침투성 치료 시스템
ATE5563T1 (de) Therapeutisches system zum zufuehren von arzneimitteln zur haut.
KR900017575A (ko) 경피 약물전달 기기 및 방법
ATE234602T1 (de) Verabreichungsform zur abgabe von steigenden wirkstoffdosen
JPH11158081A (ja) 薬剤供給システム
AU3268689A (en) Transdermal monolith systems
AU622775B2 (en) A plaster used as therapeutic system for the administration of active substances to the skin, which exhibits a graduated active substance release, process for the production of the plaster and the use thereof
GEP20002229B (en) Synthetic Membrane Vesicles, Method for Obtaining and Application of the Same
Monkhouse et al. Transdermal drug delivery-problems and promises
ES2043744T3 (es) Sistema de suministro transdermico de procaterol.
DE69429785D1 (de) Impfstoffverabreichungssystem
AR003413A1 (es) Parches medicinales para la administracion transdermica de risperidona con liberacion controlada a traves de la piel intacta durante un periodo de tiempo prolongado
US20050118245A1 (en) Assembled unit consisting of individually separable, transdermal, therapeutic systems
ES171385U (es) Vendaje medico.

Legal Events

Date Code Title Description
8332 No legal effect for de