DE69327599D1 - Adjuvantien enthaltende Impfstoffzusammensetzung - Google Patents

Adjuvantien enthaltende Impfstoffzusammensetzung

Info

Publication number
DE69327599D1
DE69327599D1 DE69327599T DE69327599T DE69327599D1 DE 69327599 D1 DE69327599 D1 DE 69327599D1 DE 69327599 T DE69327599 T DE 69327599T DE 69327599 T DE69327599 T DE 69327599T DE 69327599 D1 DE69327599 D1 DE 69327599D1
Authority
DE
Germany
Prior art keywords
composition containing
vaccine composition
containing adjuvants
adjuvants
vaccine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69327599T
Other languages
English (en)
Other versions
DE69327599T2 (de
Inventor
Jean-Paul Prieels
Nathalie Marie-Josephe Garcon
Moncef Slaoui
Pietro Pala
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
GlaxoSmithKline Biologicals SA
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9213559A external-priority patent/GB9213559D0/en
Priority claimed from GB929226283A external-priority patent/GB9226283D0/en
Priority claimed from GB939304056A external-priority patent/GB9304056D0/en
Application filed by GlaxoSmithKline Biologicals SA, SmithKline Beecham Biologicals SA filed Critical GlaxoSmithKline Biologicals SA
Application granted granted Critical
Publication of DE69327599D1 publication Critical patent/DE69327599D1/de
Publication of DE69327599T2 publication Critical patent/DE69327599T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • A61K39/292Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/002Protozoa antigens
    • A61K39/015Hemosporidia antigens, e.g. Plasmodium antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/245Herpetoviridae, e.g. herpes simplex virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/29Hepatitis virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55572Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55577Saponins; Quil A; QS21; ISCOMS
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16634Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
DE69327599T 1992-06-25 1993-06-15 Adjuvantien enthaltende Impfstoffzusammensetzung Expired - Lifetime DE69327599T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9213559A GB9213559D0 (en) 1992-06-25 1992-06-25 Vaccines
GB929226283A GB9226283D0 (en) 1992-12-17 1992-12-17 Vaccines
GB939304056A GB9304056D0 (en) 1993-03-01 1993-03-01 Vaccines

Publications (2)

Publication Number Publication Date
DE69327599D1 true DE69327599D1 (de) 2000-02-17
DE69327599T2 DE69327599T2 (de) 2000-08-10

Family

ID=27266263

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69327599T Expired - Lifetime DE69327599T2 (de) 1992-06-25 1993-06-15 Adjuvantien enthaltende Impfstoffzusammensetzung
DE69313134T Expired - Lifetime DE69313134T2 (de) 1992-06-25 1993-06-15 Adjuvantien enthaltende impfstoffzusammensetzung

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69313134T Expired - Lifetime DE69313134T2 (de) 1992-06-25 1993-06-15 Adjuvantien enthaltende impfstoffzusammensetzung

Country Status (31)

Country Link
US (2) US5750110A (de)
EP (2) EP0761231B1 (de)
JP (1) JP3755890B2 (de)
KR (1) KR100278157B1 (de)
CN (1) CN1122530C (de)
AP (1) AP408A (de)
AT (2) ATE188613T1 (de)
AU (1) AU661404B2 (de)
CA (1) CA2138997C (de)
CZ (1) CZ282235B6 (de)
DE (2) DE69327599T2 (de)
DK (2) DK0761231T3 (de)
ES (2) ES2143716T3 (de)
FI (1) FI109767B (de)
GR (2) GR3025184T3 (de)
HK (2) HK1022074A1 (de)
HU (1) HU219808B (de)
IL (1) IL106109A (de)
MA (1) MA22911A1 (de)
MX (1) MX9303773A (de)
MY (1) MY109278A (de)
NO (1) NO317546B1 (de)
NZ (1) NZ253137A (de)
PL (1) PL170980B1 (de)
PT (1) PT761231E (de)
RU (1) RU2118164C1 (de)
SG (2) SG49909A1 (de)
SI (1) SI9300335B (de)
SK (1) SK279188B6 (de)
UA (1) UA40597C2 (de)
WO (1) WO1994000153A1 (de)

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SI9300335B (sl) 2003-04-30
AP9300541A0 (en) 1993-07-31
ATE188613T1 (de) 2000-01-15
ES2108278T3 (es) 1997-12-16
SK159294A3 (en) 1995-08-09
KR950702125A (ko) 1995-06-19
FI946064A (fi) 1995-02-22
FI109767B (fi) 2002-10-15
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WO1994000153A1 (en) 1994-01-06
NO945003L (no) 1994-12-23
AP408A (en) 1995-09-27
JP3755890B2 (ja) 2006-03-15
SG90042A1 (en) 2002-07-23
NO317546B1 (no) 2004-11-15
MX9303773A (es) 1994-05-31
SG49909A1 (en) 1998-06-15
AU661404B2 (en) 1995-07-20
DE69327599T2 (de) 2000-08-10
DE69313134T2 (de) 1998-02-26
GR3032742T3 (en) 2000-06-30
PL170980B1 (pl) 1997-02-28
IL106109A0 (en) 1993-10-20
CA2138997C (en) 2003-06-03
GR3025184T3 (en) 1998-02-27
DK0671948T3 (da) 1997-09-01
EP0671948B1 (de) 1997-08-13
NO945003D0 (no) 1994-12-23
CN1086142A (zh) 1994-05-04
EP0761231B1 (de) 2000-01-12
EP0761231A1 (de) 1997-03-12
ATE156710T1 (de) 1997-08-15
CN1122530C (zh) 2003-10-01
SI9300335A (sl) 1993-12-31
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RU94046232A (ru) 1996-10-10
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US5750110A (en) 1998-05-12
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CA2138997A1 (en) 1994-01-06
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MA22911A1 (fr) 1993-12-31
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