DE69322242T2 - Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der Immunpräzipitationsreaktion - Google Patents
Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der ImmunpräzipitationsreaktionInfo
- Publication number
- DE69322242T2 DE69322242T2 DE69322242T DE69322242T DE69322242T2 DE 69322242 T2 DE69322242 T2 DE 69322242T2 DE 69322242 T DE69322242 T DE 69322242T DE 69322242 T DE69322242 T DE 69322242T DE 69322242 T2 DE69322242 T2 DE 69322242T2
- Authority
- DE
- Germany
- Prior art keywords
- analyte
- immunoprecipitation reaction
- measurement
- rate
- liquid medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/916,519 US5371021A (en) | 1992-07-17 | 1992-07-17 | Initial rate photometric method for immunoassay |
PCT/US1993/003724 WO1994002853A1 (en) | 1992-07-17 | 1993-04-21 | Initial rate photometric method for immunoassay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69322242D1 DE69322242D1 (de) | 1999-01-07 |
DE69322242T2 true DE69322242T2 (de) | 1999-04-22 |
Family
ID=25437408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69322242T Expired - Fee Related DE69322242T2 (de) | 1992-07-17 | 1993-04-21 | Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der Immunpräzipitationsreaktion |
Country Status (9)
Country | Link |
---|---|
US (2) | US5371021A (de) |
EP (1) | EP0604606B1 (de) |
JP (1) | JPH06511088A (de) |
AT (1) | ATE173829T1 (de) |
AU (1) | AU669904B2 (de) |
CA (1) | CA2116687A1 (de) |
DE (1) | DE69322242T2 (de) |
ES (1) | ES2125982T3 (de) |
WO (1) | WO1994002853A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284472B1 (en) | 1998-10-05 | 2001-09-04 | Dade Behring Inc. | Method for extending the range of an immunoassay |
US20060141470A1 (en) * | 2003-02-14 | 2006-06-29 | Kalayoglu Murat V | Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof |
ITMI20030971A1 (it) * | 2003-05-15 | 2004-11-16 | Solvay Solexis Spa | Preparazione di perfluoropolieteri aventi almeno un terminale -ch2oh oppure -ch(cf3)oh. |
EP1496362B1 (de) * | 2003-07-09 | 2006-12-13 | Matsushita Electric Industrial Co., Ltd. | Turbidimetrisches Immuntestverfahren und zugehörige Vorrichtung |
WO2005052583A1 (ja) * | 2003-11-28 | 2005-06-09 | Olympus Corporation | 分析対象物質の検出方法 |
GB2426050A (en) * | 2005-05-09 | 2006-11-15 | Orion Diagnostica Oy | Method of measuring binding rate using sonication |
US7993855B2 (en) * | 2006-03-24 | 2011-08-09 | Aokin Ag | Use of additives to lower the rate of a binding reaction |
ES2457243T3 (es) * | 2006-09-08 | 2014-04-25 | The Chancellor, Masters And Scholars Of The University Of Oxford | Diagnóstico clínico de una fibrosis hepática utilizando APOL1 de suero humano como biomarcador |
CN102460174B (zh) * | 2009-05-14 | 2016-03-16 | 牛津大学之校长及学者 | 使用一组新型低丰度人类血浆蛋白生物标记对肝纤维化进行临床诊断 |
RU2650424C1 (ru) * | 2017-02-27 | 2018-04-13 | Акционерное Общество "Концерн "Океанприбор" | Концентратомер подвижных инфузорий в жидких средах |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4305665A (en) * | 1975-01-29 | 1981-12-15 | Baxter Travenol Laboratories, Inc. | Nephelometer and nephelometer method for assaying immunochemical complex |
US4268171A (en) * | 1977-07-18 | 1981-05-19 | Beckman Instruments, Inc. | Method determining concentration in rate nephelometric immunochemical analysis |
JPS54108693A (en) * | 1978-02-14 | 1979-08-25 | Mitsubishi Chem Ind | Method and device for optically measuring antigennantibody reaction |
JPS54109494A (en) * | 1978-02-16 | 1979-08-28 | Teikoku Hormone Mfg Co Ltd | Method of measuring antigennantibody reaction |
US4204837A (en) * | 1978-03-14 | 1980-05-27 | Beckman Instruments, Inc. | Method of rate immunonephelometric analysis |
US4205954A (en) * | 1978-05-26 | 1980-06-03 | Warner-Lambert Company | Kinetic latex agglutinometry |
JPS5544903A (en) * | 1978-09-26 | 1980-03-29 | Chugai Pharmaceut Co Ltd | Method of quantitatively analyzing low molecular substance in humor |
DE2901327B1 (de) * | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Verfahren zur Bestimmung eines opsonierenden oberflaechenbindenden alpha?-Glykoproteins |
JPS57175957A (en) * | 1981-04-24 | 1982-10-29 | Chugai Pharmaceut Co Ltd | Measuring method and device for antigen- antibody reaction |
US4604365A (en) * | 1981-06-02 | 1986-08-05 | Electro-Nucleonics, Inc. | Immunoprecipitation assay |
US4766083A (en) * | 1982-04-04 | 1988-08-23 | Wako Pure Chemical Industries, Ltd. | Method for the photometric determination of biological agglutination |
DE3212658C3 (de) * | 1982-04-05 | 1993-08-19 | American Hospital Supply Corp | Verfahren zur antigen-bestimmung |
US4521521A (en) * | 1983-03-11 | 1985-06-04 | E. I. Du Pont De Nemours And Company | Particle reagent size distribution measurements for immunoassay |
US4554257A (en) * | 1983-04-29 | 1985-11-19 | Aladjem Frederick J | Assaying immunoreactive and like substances by measurement of aggregate classes |
JPH0736016B2 (ja) * | 1984-05-11 | 1995-04-19 | 和光純薬工業株式会社 | 免疫グロブリンの定量方法 |
US4647544A (en) * | 1984-06-25 | 1987-03-03 | Nicoli David F | Immunoassay using optical interference detection |
DE3615384A1 (de) * | 1985-05-08 | 1986-11-13 | Nissui Seiyaku K.K., Tokio/Tokyo | Verfahren zur bestimmung des rheumafaktors und denaturiertes, menschliches (gamma)-globulin fuer das verfahren |
JPH0660901B2 (ja) * | 1985-08-30 | 1994-08-10 | 東ソー株式会社 | 酵素免疫測定法 |
JP2524511B2 (ja) * | 1985-12-23 | 1996-08-14 | ベツクマン インスツルメンツ インコ−ポレ−テツド | 自動免疫化学分析装置及び方法 |
US4835110A (en) * | 1985-12-23 | 1989-05-30 | Beckman Instruments, Inc. | Method for enhancing analysis timing in kinetic nephelometry |
US5169757A (en) * | 1987-05-20 | 1992-12-08 | Carleton University | Antibodies or antigens bound to a macroporous hydrophobic synthetic polymer cloth for immunological techniques |
AU2128388A (en) * | 1987-07-21 | 1989-02-13 | Coulter Electronics Inc. | Improved turbidimetric rate inhibition assay for haptens |
ES2056936T3 (es) * | 1987-09-30 | 1994-10-16 | Beckman Instruments Inc | Conjugado bidentado y metodo de utilizacion del mismo. |
US5019999A (en) * | 1988-09-30 | 1991-05-28 | Technicon Instruments Corporation | Immunoanalysis method for discriminating between antigen excess and antibody excess conditions |
DE3900493A1 (de) * | 1989-01-10 | 1990-07-12 | Thomae Gmbh Dr K | Verfahren zur bestimmung der fibrinolytischen gesamtaktivitaet im plasma |
-
1992
- 1992-07-17 US US07/916,519 patent/US5371021A/en not_active Expired - Lifetime
-
1993
- 1993-04-21 AU AU42913/93A patent/AU669904B2/en not_active Ceased
- 1993-04-21 EP EP93912327A patent/EP0604606B1/de not_active Expired - Lifetime
- 1993-04-21 WO PCT/US1993/003724 patent/WO1994002853A1/en active IP Right Grant
- 1993-04-21 ES ES93912327T patent/ES2125982T3/es not_active Expired - Lifetime
- 1993-04-21 CA CA002116687A patent/CA2116687A1/en not_active Abandoned
- 1993-04-21 DE DE69322242T patent/DE69322242T2/de not_active Expired - Fee Related
- 1993-04-21 AT AT93912327T patent/ATE173829T1/de not_active IP Right Cessation
- 1993-04-21 JP JP6504425A patent/JPH06511088A/ja active Pending
-
1994
- 1994-09-06 US US08/301,236 patent/US5583055A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0604606A1 (de) | 1994-07-06 |
DE69322242D1 (de) | 1999-01-07 |
JPH06511088A (ja) | 1994-12-08 |
EP0604606B1 (de) | 1998-11-25 |
AU4291393A (en) | 1994-02-14 |
ES2125982T3 (es) | 1999-03-16 |
CA2116687A1 (en) | 1994-02-03 |
AU669904B2 (en) | 1996-06-27 |
US5583055A (en) | 1996-12-10 |
US5371021A (en) | 1994-12-06 |
ATE173829T1 (de) | 1998-12-15 |
WO1994002853A1 (en) | 1994-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |