DE69321945D1 - Filme auf copolymerenbasis, deren verwendungen in transdermalen systemen und deren herstellungsverfahren - Google Patents

Filme auf copolymerenbasis, deren verwendungen in transdermalen systemen und deren herstellungsverfahren

Info

Publication number
DE69321945D1
DE69321945D1 DE69321945T DE69321945T DE69321945D1 DE 69321945 D1 DE69321945 D1 DE 69321945D1 DE 69321945 T DE69321945 T DE 69321945T DE 69321945 T DE69321945 T DE 69321945T DE 69321945 D1 DE69321945 D1 DE 69321945D1
Authority
DE
Germany
Prior art keywords
pct
acid
methacrylate
sec
transdermal systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69321945T
Other languages
English (en)
Other versions
DE69321945T2 (de
Inventor
Michel Istin
Jean-Marc Grognet
Charles Darnez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIO HOLDING
Original Assignee
BIO HOLDING
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIO HOLDING filed Critical BIO HOLDING
Application granted granted Critical
Publication of DE69321945D1 publication Critical patent/DE69321945D1/de
Publication of DE69321945T2 publication Critical patent/DE69321945T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
DE69321945T 1992-12-21 1993-12-20 Filme auf copolymerenbasis, deren verwendungen in transdermalen systemen und deren herstellungsverfahren Expired - Fee Related DE69321945T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9215377A FR2699406B1 (fr) 1992-12-21 1992-12-21 Films à base de copolymères, leurs applications dans des systèmes transdermiques et leurs procédés de préparation.
PCT/FR1993/001272 WO1994014425A1 (fr) 1992-12-21 1993-12-20 Films a base de copolymeres, leurs applications dans des systemes transdermiques et leurs procedes de preparation

Publications (2)

Publication Number Publication Date
DE69321945D1 true DE69321945D1 (de) 1998-12-10
DE69321945T2 DE69321945T2 (de) 1999-04-01

Family

ID=9436836

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69321945T Expired - Fee Related DE69321945T2 (de) 1992-12-21 1993-12-20 Filme auf copolymerenbasis, deren verwendungen in transdermalen systemen und deren herstellungsverfahren

Country Status (12)

Country Link
US (1) US5556635A (de)
EP (1) EP0625901B1 (de)
JP (1) JPH07508291A (de)
KR (1) KR100314123B1 (de)
AT (1) ATE172877T1 (de)
CA (1) CA2130332A1 (de)
DE (1) DE69321945T2 (de)
DK (1) DK0625901T3 (de)
ES (1) ES2126739T3 (de)
FR (1) FR2699406B1 (de)
MX (1) MX9400223A (de)
WO (1) WO1994014425A1 (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE149349T1 (de) 1993-06-25 1997-03-15 Alza Corp Einarbeitung eines poly-n-vinylamids in ein transdermales system
FR2745720B1 (fr) * 1996-03-08 1998-05-07 Soc D Pharmacologie Et D Immun Dispositif de diffusion d'un produit volatil dans l'atmosphere
US5882675A (en) * 1996-03-09 1999-03-16 Nitto Denko Corporation Percutaneous absorption preparation
ATE302599T1 (de) 1996-05-24 2005-09-15 Angiotech Pharm Inc Zubereitungen und verfahren zur behandlung oder prävention von krankheiten der körperpassagewege
JP4477152B2 (ja) * 1997-05-16 2010-06-09 株式会社共和 ストーマ用又は瘡傷用の皮膚保護材
DE19812688A1 (de) * 1998-03-23 1999-09-30 Basf Ag Verfahren zur Herstellung von festen Dosierungsformen
FR2803204B1 (fr) * 1999-12-30 2002-05-03 Ethymed Lab Dispositif de diffusion d'un produit volatil et procede de preparation
US20020004065A1 (en) 2000-01-20 2002-01-10 David Kanios Compositions and methods to effect the release profile in the transdermal administration of active agents
DE10025971B4 (de) * 2000-05-25 2004-09-02 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System in Plasterform mit verminderter Tendenz zur Wirkstoffkristallisation und seine Verwendung
DE10025970C2 (de) * 2000-05-25 2002-04-25 Lohmann Therapie Syst Lts Estrogenhaltiges Pflaster mit einem Wirkstoffreservoir auf der Basis von Ethylcellulose und einem Ethylen-Vinylacetat-Vinylpyrrolidon-Copolymer und seine Verwendung
AU2001281304B2 (en) * 2000-08-15 2006-05-25 Surmodics, Inc. Medicament incorporation matrix
US6479076B2 (en) * 2001-01-12 2002-11-12 Izhak Blank Nicotine delivery compositions
US7497623B2 (en) 2002-02-27 2009-03-03 Pactiv Corporation Packages with active agents
US20060110080A1 (en) * 2002-02-27 2006-05-25 Thomas Toby R Packages and structures with selective dosing of active agent
US20060291756A1 (en) * 2002-02-27 2006-12-28 Thomas Toby R Web materials with active agent for use in forming reclosable packages
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
CN104397869B (zh) 2003-11-07 2016-06-08 美国无烟烟草有限责任公司 烟草组合物
JP5000932B2 (ja) * 2005-06-21 2012-08-15 日東電工株式会社 ニコチン含有経皮吸収製剤
AU2011239636A1 (en) 2010-04-13 2012-11-22 Najib Babul Dermal pharmaceutical compositions of 1-Methyl-2',6'-pipecoloxylidide and method of use
EP2560893B1 (de) * 2010-04-18 2017-10-04 Gevaram Quality Envelopes Ltd. Sicherheits-versandtasche
HUE055562T2 (hu) 2011-11-23 2021-11-29 Therapeuticsmd Inc Természetes kombinációjú hormon helyettesítõ kiszerelések, és terápiák ezekkel
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
EP3145489A1 (de) 2014-05-22 2017-03-29 TherapeuticsMD, Inc. Natürliche kombinierte hormonersatzformulierungen und therapien
EP3034531A1 (de) * 2014-12-19 2016-06-22 Evonik Degussa GmbH Dispersion zum einfachen Einsatz in der Herstellung von Verkapselungsfolien
EP3034527B1 (de) 2014-12-19 2017-05-31 Evonik Degussa GmbH Covernetzersysteme für Verkapselungsfolien umfassend Bis-(alkenylamid)-Verbindungen
EP3034528B1 (de) 2014-12-19 2017-06-21 Evonik Degussa GmbH Covernetzersysteme für Verkapselungsfolien umfassend Harnstoffverbindungen
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
BR112018070199A2 (pt) 2016-04-01 2019-01-29 Therapeuticsmd Inc composição farmacêutica de hormônio esteroide
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2250793B1 (de) * 1973-11-09 1978-12-29 Commissariat Energie Atomique
FR2513243B1 (de) * 1981-09-24 1983-11-18 Commissariat Energie Atomique
US4994267A (en) * 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
PT100502A (pt) * 1991-05-20 1993-08-31 Alza Corp Composicoes farmaceuticas para aumentar a capacidade de permeacao na pele utilizando monolinoleato de glicerol

Also Published As

Publication number Publication date
FR2699406B1 (fr) 1995-03-10
DE69321945T2 (de) 1999-04-01
ES2126739T3 (es) 1999-04-01
WO1994014425A1 (fr) 1994-07-07
JPH07508291A (ja) 1995-09-14
MX9400223A (es) 1994-07-29
US5556635A (en) 1996-09-17
DK0625901T3 (da) 1999-07-19
KR950700729A (ko) 1995-02-20
ATE172877T1 (de) 1998-11-15
EP0625901B1 (de) 1998-11-04
CA2130332A1 (fr) 1994-07-07
FR2699406A1 (fr) 1994-06-24
EP0625901A1 (de) 1994-11-30
KR100314123B1 (ko) 2002-04-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee