DE69233749D1 - Durchflusszelle mit einer inneren Schicht aus amorphem Fluoropolymer, dessen Brechungindex kleiner ist als der von Wasser - Google Patents

Durchflusszelle mit einer inneren Schicht aus amorphem Fluoropolymer, dessen Brechungindex kleiner ist als der von Wasser

Info

Publication number
DE69233749D1
DE69233749D1 DE69233749T DE69233749T DE69233749D1 DE 69233749 D1 DE69233749 D1 DE 69233749D1 DE 69233749 T DE69233749 T DE 69233749T DE 69233749 T DE69233749 T DE 69233749T DE 69233749 D1 DE69233749 D1 DE 69233749D1
Authority
DE
Germany
Prior art keywords
water
less
refractive index
inner layer
flow cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233749T
Other languages
English (en)
Inventor
Anthony C Gilby
William W Carson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waters Technologies Corp
Original Assignee
Waters Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Investments Ltd filed Critical Waters Investments Ltd
Application granted granted Critical
Publication of DE69233749D1 publication Critical patent/DE69233749D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02Optical fibres with cladding with or without a coating
    • G02B6/032Optical fibres with cladding with or without a coating with non solid core or cladding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/0303Optical path conditioning in cuvettes, e.g. windows; adapted optical elements or systems; path modifying or adjustment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N21/05Flow-through cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03Cuvette constructions
    • G01N2021/0346Capillary cells; Microcells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S138/00Pipes and tubular conduits
    • Y10S138/03Polytetrafluoroethylene, i.e. PTFE
DE69233749T 1991-07-17 1992-07-15 Durchflusszelle mit einer inneren Schicht aus amorphem Fluoropolymer, dessen Brechungindex kleiner ist als der von Wasser Expired - Lifetime DE69233749D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/731,677 US5184192A (en) 1991-07-17 1991-07-17 Photometric apparatus with a flow cell coated with an amorphous fluoropolymer

Publications (1)

Publication Number Publication Date
DE69233749D1 true DE69233749D1 (de) 2008-12-04

Family

ID=24940524

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69232365T Expired - Lifetime DE69232365T2 (de) 1991-07-17 1992-07-15 Photometrisches Gerät
DE69233749T Expired - Lifetime DE69233749D1 (de) 1991-07-17 1992-07-15 Durchflusszelle mit einer inneren Schicht aus amorphem Fluoropolymer, dessen Brechungindex kleiner ist als der von Wasser
DE0523680T Pending DE523680T1 (de) 1991-07-17 1992-07-15 Photometrisches Gerät.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69232365T Expired - Lifetime DE69232365T2 (de) 1991-07-17 1992-07-15 Photometrisches Gerät

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0523680T Pending DE523680T1 (de) 1991-07-17 1992-07-15 Photometrisches Gerät.

Country Status (4)

Country Link
US (1) US5184192A (de)
EP (2) EP1106988B1 (de)
JP (1) JP3260431B2 (de)
DE (3) DE69232365T2 (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4709793A (en) * 1992-08-13 1994-03-15 Meinrad Machler Spectroscopic systems for the analysis of small and very small quantities of substances
US5608517A (en) * 1995-02-28 1997-03-04 Thermo Separation Products Inc. Flow cell and method for making same
US6199257B1 (en) * 1995-02-28 2001-03-13 Thermo Separation Products, Inc. Method of making a flow cell for light absorption measurement of small volume samples
EP0762119B1 (de) * 1995-09-06 2001-12-05 Agilent Technologies Deutschland GmbH Photometrische Durchflussvorrichtung für kleine Probenvolumina
DE19817738C2 (de) * 1998-04-21 2003-02-06 Karl-Friedrich Klein Hohle optische Wellenleiter für die Spurenanalyse in wässrigen Lösungen
US6342948B1 (en) * 1998-11-20 2002-01-29 Waters Investments Limited Dual pathlength system for light absorbance detection
US6188813B1 (en) * 1999-02-10 2001-02-13 Waters Investments Limited Flow cell, analyte measurement apparatus and methods related thereto
US6332049B1 (en) 2000-01-22 2001-12-18 Global Fia, Inc. Luminescence detector with liquid-core waveguide
DE10028067C1 (de) 2000-04-14 2001-08-23 Danfoss As Verfahren zur optischen Analyse eines Fluids
MXPA02010596A (es) * 2000-04-26 2003-03-10 Glaxo Group Ltd Metodo y aparato para el analisis espectroscopico in -situ.
US6542231B1 (en) * 2000-08-22 2003-04-01 Thermo Finnegan Llc Fiber-coupled liquid sample analyzer with liquid flow cell
WO2002029397A2 (en) * 2000-10-05 2002-04-11 E.I. Du Pont De Nemours And Company Polymeric microfabricated fluidic device suitable for ultraviolet detection
US6603556B2 (en) 2000-10-12 2003-08-05 World Precision Instruments, Inc. Photometric detection system having multiple path length flow cell
US6558626B1 (en) * 2000-10-17 2003-05-06 Nomadics, Inc. Vapor sensing instrument for ultra trace chemical detection
US20020072111A1 (en) 2000-12-13 2002-06-13 Clarkin James P. Drawn microchannel array devices and method of analysis using same
US6678051B2 (en) 2001-01-18 2004-01-13 Systec, Inc. Flow cells utilizing photometric techniques
WO2002071029A1 (en) * 2001-03-02 2002-09-12 Waters Investments Limited Fluorescence detector geometry
US6797139B2 (en) 2001-03-19 2004-09-28 Applera Corporation Detection cell for guiding excitation light therein and method for using same
WO2002088686A1 (en) * 2001-04-27 2002-11-07 Genetic Id Waveguide and assay
US7250098B2 (en) * 2001-09-28 2007-07-31 Applera Corporation Multi-capillary array electrophoresis device
DE60126781D1 (de) 2001-10-24 2007-04-05 Agilent Technologies Inc Verfahen zur Herstellung einer Durchflusszelle
DE10157275A1 (de) * 2001-11-22 2003-06-05 Zeiss Carl Jena Gmbh Gasprobenbehälter für einen Gasanalysator
AU2003213294A1 (en) * 2002-02-25 2003-09-09 Waters Investments Limited An opaque additive to block stray light in teflon af light-guiding flowcells
JP2003279471A (ja) * 2002-03-20 2003-10-02 Nippon Sheet Glass Co Ltd マイクロ化学システム用チップ及びマイクロ化学システム
US7108775B2 (en) * 2002-11-08 2006-09-19 Applera Corporation Apparatus and method for confining eluted samples in electrophoresis systems
WO2004099757A1 (en) * 2003-04-07 2004-11-18 Systec, Inc. Flow cells utilizing photometric techniques
US7050660B2 (en) * 2003-04-07 2006-05-23 Eksigent Technologies Llc Microfluidic detection device having reduced dispersion and method for making same
JP4061241B2 (ja) * 2003-05-13 2008-03-12 ジーエルサイエンス株式会社 キャピラリーチューブフローセル
US7444053B2 (en) * 2003-06-16 2008-10-28 The Regents Of The University Of California Integrated electrical and optical sensor for biomolecule analysis with single molecule sensitivity
US7248771B2 (en) * 2003-06-16 2007-07-24 Brigham Young University Integrated sensor with electrical and optical single molecule sensitivity
WO2004113957A2 (en) * 2003-06-16 2004-12-29 The Regents Of The University Of California Apparatus for optical measurements on low-index non-solid materials based on arrow waveguides
US20050063869A1 (en) * 2003-09-24 2005-03-24 Stephane Follonier Device, system and method of detecting targets in a fluid sample
WO2005050187A1 (en) * 2003-11-05 2005-06-02 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Methods and devices for measuring fluorescence of a sample in a capillary
US20050161623A1 (en) * 2004-01-27 2005-07-28 Carver David R. Apparatus for measuring photoluminescing species such as those found in liquid chromatography and capillary electrophoresis and process for making same
US7261813B2 (en) * 2004-08-10 2007-08-28 Clemson University Monolithic structures comprising polymeric fibers for chemical separation by liquid chromatography
US7740763B2 (en) 2004-08-10 2010-06-22 Clemson University Capillary-channeled polymeric fiber as solid phase extraction media
JP2006208344A (ja) * 2004-12-28 2006-08-10 Bl Tec Kk 吸光光度自動定量分析方法、吸光光度自動定量分析装置及びこれらに用いられるセル
US7259840B1 (en) * 2004-12-28 2007-08-21 Systec, Llc Fluid analysis apparatus
US7298472B2 (en) * 2004-12-28 2007-11-20 Rheodyne, Llc Fluid analysis apparatus
JP2006234601A (ja) * 2005-02-25 2006-09-07 Bl Tec Kk 吸光光度自動定量分析装置
JP4812393B2 (ja) * 2005-03-04 2011-11-09 株式会社日立ハイテクノロジーズ 蛍光分子計測システム
US7565042B2 (en) * 2005-10-03 2009-07-21 Creatv Microtech, Inc. Sensitive emission light gathering and flow through detection system
US7224449B2 (en) * 2005-10-21 2007-05-29 Agilent Technologies, Inc. Optical fluidic system with a capillary having a drilled through hole
US7427745B2 (en) * 2005-10-21 2008-09-23 Nokia Corporation Optical shutter for miniature cameras
US7386199B2 (en) * 2005-12-22 2008-06-10 Palo Alto Research Center Incorporated Providing light to channels or portions
US7605916B2 (en) * 2006-09-21 2009-10-20 Intel Corporation Online analyte detection by surface enhanced Raman scattering (SERS)
US7914852B2 (en) * 2007-01-19 2011-03-29 World Precision Instruments, Inc. High temperature coating techniques for amorphous fluoropolymers
JP5159247B2 (ja) * 2007-10-26 2013-03-06 キヤノン株式会社 検出方法および検出装置
DE102007054309A1 (de) 2007-11-08 2009-05-14 Laser- und Medizin-Technologie GmbH, Berlin (LMTB) Optische Anordnung zur Erhöhung der Wechselwirkungslänge in stark steuernder Matrix
TW201005288A (en) * 2008-06-30 2010-02-01 Asahi Glass Co Ltd Process for analyzing low molecular weight organic compound having at most 20 carbon atoms in cloth made of chemical fibers treated with water and oil repellent agent
US8213015B2 (en) * 2008-09-25 2012-07-03 Agilent Technologies, Inc. Integrated flow cell with semiconductor oxide tubing
US8665439B2 (en) * 2009-06-30 2014-03-04 Microbix Biosystems, Inc. Method and apparatus for limiting effects of refraction in cytometry
US20110149286A1 (en) * 2009-12-18 2011-06-23 Chih-Wei Wu Liquid core waveguide assembly and detecting system including the same
DE102010051928B4 (de) * 2010-11-19 2012-08-09 Tutech Innovation Gmbh Gaszelle zur optischen Analyse von Gasen
EP2676121A1 (de) 2011-02-15 2013-12-25 Microbix Biosystems Inc. Verfahren, systeme, und vorrichtung für durchflusszytometrie
GB201110454D0 (en) 2011-06-21 2011-08-03 College The Microfluidic photoporation
CN103076207A (zh) * 2011-10-25 2013-05-01 天津市蓝宇科工贸有限公司 采样池
JP5883631B2 (ja) 2011-12-08 2016-03-15 株式会社日立ハイテクノロジーズ フローセル及び液体分析装置
US9752978B2 (en) 2012-02-03 2017-09-05 Agilent Technologies, Inc. Micromachined flow cell with freestanding fluidic tube
JP5915451B2 (ja) * 2012-08-21 2016-05-11 株式会社島津製作所 フローセル
US8760658B2 (en) 2012-10-12 2014-06-24 Perkinelmer Health Sciences, Inc. Flow cell modules and liquid sample analyzers and methods including same
US9007595B2 (en) 2012-10-12 2015-04-14 Perkinelmer Health Sciences, Inc. Lamp temperature management systems and methods for liquid chromatography analyzers
US8797528B2 (en) 2012-10-12 2014-08-05 Perkinelmer Health Sciences, Inc. Flow cell assembly for liquid sample analyzer
CN103852454A (zh) * 2012-12-06 2014-06-11 武汉鹰飞拓光电子有限公司 便携式爆炸品和毒品探测器
US20160207795A1 (en) * 2013-09-24 2016-07-21 Asahi Organic Chemicals Industry Co., Ltd. Ultraviolet sterilization device
US9146189B2 (en) * 2014-02-28 2015-09-29 Asl Analytical, Inc. Optical cell with disposable fluid cartridge
WO2016081727A1 (en) * 2014-11-20 2016-05-26 Drexel University Flow cells and methods of measuring an absorption spectrum of a sample
GB201508115D0 (en) * 2015-05-12 2015-06-24 Univ Cranfield Hollow fibre waveguide gas cells
WO2019084766A1 (zh) * 2017-10-31 2019-05-09 深圳大学 一种混合型光纤耦合器及其制备方法
CN111819153A (zh) * 2017-12-23 2020-10-23 路玛赛特有限责任公司 利用微流控芯片构型和动力学进行光力测量和细胞成像的微流控芯片设备
US10871440B2 (en) 2017-12-23 2020-12-22 Lumacyte, LLC Microfluidic chip device for optical force measurements and cell imaging using microfluidic chip configuration and dynamics
RU186501U1 (ru) * 2018-08-02 2019-01-22 Федеральное государственное бюджетное образовательное учреждение высшего образования "Российский химико-технологический университет имени Д.И. Менделеева" (РХТУ им. Д.И. Менделеева) Устройство спектрофотометрической проточной кюветы
US20220091036A1 (en) * 2018-10-05 2022-03-24 Provigate Inc. Trace substance optical measuring instrument and measuring method
CN110531013A (zh) * 2019-08-30 2019-12-03 大连依利特分析仪器有限公司 一种利用毛细管管壁轴向全反射的检测池

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3954341A (en) 1974-09-30 1976-05-04 Technicon Instruments Corporation Liquid sample analyzer with improved optical characteristics
US4260257A (en) * 1979-05-29 1981-04-07 Neeley William E Flow cell
SE455134B (sv) * 1981-01-14 1988-06-20 Leon Carlson Sett och anordning vid optisk analys i genomstromningskuvett
US4754009A (en) * 1981-08-20 1988-06-28 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
US4948851A (en) * 1981-08-20 1990-08-14 E. I. Du Pont De Nemours And Company Amorphous copolymers of perfluoro-2,2-dimethyl-1,3-dioxole
JP2735546B2 (ja) * 1986-04-16 1998-04-02 ザ・パ−キン−エルマ−・コ−ポレイシヨン 電気泳動計測器に使用するための毛管構成部材の製造法
US4816123A (en) * 1986-04-16 1989-03-28 The Perkin-Elmer Corporation Method of fabricating capillary electrophoresis separation channels
US5061024C1 (en) * 1989-09-06 2002-02-26 Dupont Photomasks Inc Amorphous fluoropolymer pellicle films
DE4024445C2 (de) * 1990-08-01 2000-06-08 Guenther Nath Beleuchtungseinrichtung zur Übertragung des Lichtes einer Lichtquelle mittels eines Flüssigkeitslichtleiters
US5570447A (en) * 1995-08-17 1996-10-29 World Precision Instruments, Inc. Aqueous fluid core waveguide

Also Published As

Publication number Publication date
JP3260431B2 (ja) 2002-02-25
US5184192A (en) 1993-02-02
JPH05196565A (ja) 1993-08-06
EP1106988A2 (de) 2001-06-13
EP0523680A3 (en) 1993-09-08
DE523680T1 (de) 1997-01-30
EP0523680B1 (de) 2002-01-23
DE69232365D1 (de) 2002-03-14
EP1106988B1 (de) 2008-10-22
EP0523680A2 (de) 1993-01-20
DE69232365T2 (de) 2002-10-02
EP1106988A3 (de) 2001-06-27

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Owner name: WATERS TECHNOLOGIES CORP. (N.D.GES.D. STAATES , US

8328 Change in the person/name/address of the agent

Representative=s name: DR. VOLKER VOSSIUS, CORINNA VOSSIUS, TILMAN VOSSIU

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