DE69233459D1 - Herstellung von gamma-linolensäure durch eine delta-6 desaturase - Google Patents

Herstellung von gamma-linolensäure durch eine delta-6 desaturase

Info

Publication number
DE69233459D1
DE69233459D1 DE69233459T DE69233459T DE69233459D1 DE 69233459 D1 DE69233459 D1 DE 69233459D1 DE 69233459 T DE69233459 T DE 69233459T DE 69233459 T DE69233459 T DE 69233459T DE 69233459 D1 DE69233459 D1 DE 69233459D1
Authority
DE
Germany
Prior art keywords
delta
desaturase
gamma
preparation
linolic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233459T
Other languages
English (en)
Other versions
DE69233459T2 (de
Inventor
Terry Thomas
S Reddy
Michael Nuccio
Georges Freyssinet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer SAS
Original Assignee
Bayer CropScience SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer CropScience SA filed Critical Bayer CropScience SA
Application granted granted Critical
Publication of DE69233459D1 publication Critical patent/DE69233459D1/de
Publication of DE69233459T2 publication Critical patent/DE69233459T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083Miscellaneous (1.14.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/19Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water (1.14.19)
    • C12Y114/19003Linoleoyl-CoA desaturase (1.14.19.3)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/825Bacteria
DE69233459T 1991-10-10 1992-10-13 Herstellung von gamma-linolensäure durch eine delta-6 desaturase Expired - Lifetime DE69233459T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US77447591A 1991-10-10 1991-10-10
US774475 1991-10-10
US81791992A 1992-01-08 1992-01-08
US817919 1992-01-08
PCT/US1992/008746 WO1993006712A1 (en) 1991-10-10 1992-10-13 Production of gamma linolenic acid by a δ6-desaturase

Publications (2)

Publication Number Publication Date
DE69233459D1 true DE69233459D1 (de) 2005-01-20
DE69233459T2 DE69233459T2 (de) 2005-12-15

Family

ID=27118889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233459T Expired - Lifetime DE69233459T2 (de) 1991-10-10 1992-10-13 Herstellung von gamma-linolensäure durch eine delta-6 desaturase

Country Status (23)

Country Link
US (3) US5552306A (de)
EP (1) EP0666918B1 (de)
JP (1) JP3537434B2 (de)
KR (1) KR100316068B1 (de)
CN (2) CN1053469C (de)
AT (1) ATE284961T1 (de)
AU (1) AU667848B2 (de)
BG (1) BG61791B1 (de)
BR (1) BR9206613A (de)
CA (1) CA2120629C (de)
CZ (1) CZ285471B6 (de)
DE (1) DE69233459T2 (de)
DK (1) DK0666918T3 (de)
ES (1) ES2231767T3 (de)
HU (1) HU217328B (de)
IL (1) IL103407A (de)
MX (1) MX9205820A (de)
NZ (1) NZ244685A (de)
PH (1) PH31293A (de)
RO (1) RO113256B1 (de)
RU (1) RU2152996C2 (de)
UA (1) UA43314C2 (de)
WO (1) WO1993006712A1 (de)

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CA2120629A1 (en) 1993-04-15
ATE284961T1 (de) 2005-01-15
DE69233459T2 (de) 2005-12-15
CA2120629C (en) 2009-02-17
JPH07503605A (ja) 1995-04-20
ES2231767T3 (es) 2005-05-16
CN1072722A (zh) 1993-06-02
US5663068A (en) 1997-09-02
KR100316068B1 (ko) 2002-11-13
RU2152996C2 (ru) 2000-07-20
UA43314C2 (uk) 2001-12-17
HUT69781A (en) 1995-09-28
HU9401007D0 (en) 1994-08-29
EP0666918A1 (de) 1995-08-16
NZ244685A (en) 1994-06-27
HU217328B (hu) 1999-12-28
US5552306A (en) 1996-09-03
IL103407A0 (en) 1993-03-15
IL103407A (en) 1999-09-22
BR9206613A (pt) 1995-04-11
CN1174236A (zh) 1998-02-25
AU667848B2 (en) 1996-04-18
CZ285471B6 (cs) 1999-08-11
BG61791B1 (bg) 1998-06-30
WO1993006712A1 (en) 1993-04-15
BG98695A (bg) 1995-05-31
CZ81794A3 (en) 1995-09-13
CN1053469C (zh) 2000-06-14
PH31293A (en) 1998-07-06
EP0666918B1 (de) 2004-12-15
RO113256B1 (ro) 1998-05-29
US5689050A (en) 1997-11-18
EP0666918A4 (de) 1995-03-17
CN1121499C (zh) 2003-09-17
AU2881292A (en) 1993-05-03
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DK0666918T3 (da) 2005-03-14
MX9205820A (es) 1993-04-01

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