DE69233087T2 - Verfahren zur Herstellung von Polymerarrays - Google Patents

Verfahren zur Herstellung von Polymerarrays

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Publication number
DE69233087T2
DE69233087T2 DE69233087T DE69233087T DE69233087T2 DE 69233087 T2 DE69233087 T2 DE 69233087T2 DE 69233087 T DE69233087 T DE 69233087T DE 69233087 T DE69233087 T DE 69233087T DE 69233087 T2 DE69233087 T2 DE 69233087T2
Authority
DE
Germany
Prior art keywords
different
polymer
dispenser
localized area
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233087T
Other languages
English (en)
Other versions
DE69233087D1 (de
Inventor
James Winkler
Stephen P A Fodor
Christopher Buchko
Debra A Ross
Lois Aldwin
Douglas N Modlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affymetrix Inc
Original Assignee
Affymetrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27121714&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69233087(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/796,243 external-priority patent/US5384261A/en
Priority claimed from US07/874,849 external-priority patent/US5412087A/en
Application filed by Affymetrix Inc filed Critical Affymetrix Inc
Publication of DE69233087D1 publication Critical patent/DE69233087D1/de
Application granted granted Critical
Publication of DE69233087T2 publication Critical patent/DE69233087T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/045—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers using devices to improve synthesis, e.g. reactors, special vessels
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
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    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • G—PHYSICS
    • G01—MEASURING; TESTING
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer
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EP0624059A4 (en) 1994-12-21
EP1086742A1 (de) 2001-03-28
DE69233331T2 (de) 2005-02-17
DE69233501T2 (de) 2006-02-23
JP2006194897A (ja) 2006-07-27
AU3148193A (en) 1993-06-15
HK1025278A1 (en) 2003-04-23
EP0624059A1 (de) 1994-11-17
JP2003061657A (ja) 2003-03-04
DE69233087D1 (de) 2003-07-03
EP0916396A2 (de) 1999-05-19
DE69233501D1 (de) 2005-05-19
EP1086742B2 (de) 2007-03-14
EP1588761A2 (de) 2005-10-26
EP0916396B1 (de) 2005-04-13
EP0916396A3 (de) 2000-01-19
DE69233331D1 (de) 2004-04-29
JPH07506561A (ja) 1995-07-20
CA2124087C (en) 2002-10-01
ATE293011T1 (de) 2005-04-15
EP1086742B1 (de) 2004-03-24
EP0972564A3 (de) 2000-05-10
JP3939338B2 (ja) 2007-07-04
DE69233331T3 (de) 2007-08-30
WO1993009668A1 (en) 1993-05-27
EP0972564B1 (de) 2003-05-28
ATE241426T1 (de) 2003-06-15
AU675054B2 (en) 1997-01-23
US6040193A (en) 2000-03-21
ATE262374T1 (de) 2004-04-15
EP1588761A3 (de) 2005-11-23
EP0972564A2 (de) 2000-01-19
CA2124087A1 (en) 1993-05-27
US6136269A (en) 2000-10-24
US5677195A (en) 1997-10-14

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