DE69232266T2 - Transplantat zur unterstützung von autogenem gewebewachstum - Google Patents

Transplantat zur unterstützung von autogenem gewebewachstum

Info

Publication number
DE69232266T2
DE69232266T2 DE69232266T DE69232266T DE69232266T2 DE 69232266 T2 DE69232266 T2 DE 69232266T2 DE 69232266 T DE69232266 T DE 69232266T DE 69232266 T DE69232266 T DE 69232266T DE 69232266 T2 DE69232266 T2 DE 69232266T2
Authority
DE
Germany
Prior art keywords
tissue
tunica
transplant
support
tissue growth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232266T
Other languages
English (en)
Other versions
DE69232266D1 (de
Inventor
F Badylak
A Geddes
K Shelbourne
C Lantz
C Coffey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Methodist Hospital of Indiana Inc
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25071874&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69232266(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of DE69232266D1 publication Critical patent/DE69232266D1/de
Application granted granted Critical
Publication of DE69232266T2 publication Critical patent/DE69232266T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/11Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis
    • A61B17/1146Surgical instruments, devices or methods, e.g. tourniquets for performing anastomosis; Buttons for anastomosis of tendons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/08Muscles; Tendons; Ligaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3629Intestinal tissue, e.g. small intestinal submucosa
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/365Bones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645Connective tissue
    • A61L27/3662Ligaments, tendons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3695Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the function or physical properties of the final product, where no specific conditions are defined to achieve this
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/915Method or apparatus for preparing biological material
DE69232266T 1991-09-24 1992-09-21 Transplantat zur unterstützung von autogenem gewebewachstum Expired - Lifetime DE69232266T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/764,818 US5281422A (en) 1991-09-24 1991-09-24 Graft for promoting autogenous tissue growth
PCT/US1992/008047 WO1993005798A1 (en) 1991-09-24 1992-09-21 Graft for promoting autogenous tissue growth

Publications (2)

Publication Number Publication Date
DE69232266D1 DE69232266D1 (de) 2002-01-17
DE69232266T2 true DE69232266T2 (de) 2002-08-14

Family

ID=25071874

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232266T Expired - Lifetime DE69232266T2 (de) 1991-09-24 1992-09-21 Transplantat zur unterstützung von autogenem gewebewachstum

Country Status (10)

Country Link
US (4) US5281422A (de)
EP (1) EP0605581B1 (de)
JP (1) JP3544660B2 (de)
AT (1) ATE209926T1 (de)
AU (1) AU668520B2 (de)
CA (1) CA2119750A1 (de)
DE (1) DE69232266T2 (de)
MX (1) MX9205388A (de)
NZ (1) NZ244475A (de)
WO (1) WO1993005798A1 (de)

Families Citing this family (505)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5904717A (en) * 1986-01-28 1999-05-18 Thm Biomedical, Inc. Method and device for reconstruction of articular cartilage
US5391170A (en) * 1991-12-13 1995-02-21 David A. McGuire Angled surgical screw driver and methods of arthroscopic ligament reconstruction
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US6653291B1 (en) * 1992-11-13 2003-11-25 Purdue Research Foundation Composition and method for production of transformed cells
US5641518A (en) * 1992-11-13 1997-06-24 Purdue Research Foundation Method of repairing bone tissue
DE69433101T2 (de) * 1993-06-04 2004-06-03 Smith & Nephew, Inc., Memphis Chirurgisches Befestigungselement
US5556428A (en) * 1993-09-29 1996-09-17 Shah; Mrugesh K. Apparatus and method for promoting growth and repair of soft tissue
US5769893A (en) * 1993-09-29 1998-06-23 Shah; Mrugesh K. Apparatus and method for promoting growth and repair of soft tissue
AU8095694A (en) * 1993-10-28 1995-05-22 Thm Biomedical, Inc. Improved process and device for treating and healing a bone void
US6334872B1 (en) * 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US5942496A (en) 1994-02-18 1999-08-24 The Regent Of The University Of Michigan Methods and compositions for multiple gene transfer into bone cells
US6074840A (en) 1994-02-18 2000-06-13 The Regents Of The University Of Michigan Recombinant production of latent TGF-beta binding protein-3 (LTBP-3)
US20020193338A1 (en) * 1994-02-18 2002-12-19 Goldstein Steven A. In vivo gene transfer methods for wound healing
US5962427A (en) 1994-02-18 1999-10-05 The Regent Of The University Of Michigan In vivo gene transfer methods for wound healing
US5763416A (en) 1994-02-18 1998-06-09 The Regent Of The University Of Michigan Gene transfer into bone cells and tissues
US6551618B2 (en) * 1994-03-15 2003-04-22 University Of Birmingham Compositions and methods for delivery of agents for neuronal regeneration and survival
US6475232B1 (en) 1996-12-10 2002-11-05 Purdue Research Foundation Stent with reduced thrombogenicity
ATE310839T1 (de) * 1994-04-29 2005-12-15 Scimed Life Systems Inc Stent mit kollagen
US5981825A (en) 1994-05-13 1999-11-09 Thm Biomedical, Inc. Device and methods for in vivo culturing of diverse tissue cells
US6802862B1 (en) 1995-01-24 2004-10-12 Smith & Nephew, Inc. Method for soft tissue reconstruction
US6235057B1 (en) * 1995-01-24 2001-05-22 Smith & Nephew, Inc. Method for soft tissue reconstruction
US5695998A (en) * 1995-02-10 1997-12-09 Purdue Research Foundation Submucosa as a growth substrate for islet cells
US6485723B1 (en) 1995-02-10 2002-11-26 Purdue Research Foundation Enhanced submucosal tissue graft constructs
DE69622548T2 (de) * 1995-04-07 2003-09-18 Purdue Research Foundation West Lafayette Gewebetransplantat zur blasenrekonstruktion
US5733337A (en) * 1995-04-07 1998-03-31 Organogenesis, Inc. Tissue repair fabric
US20020095218A1 (en) * 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
US5554389A (en) * 1995-04-07 1996-09-10 Purdue Research Foundation Urinary bladder submucosa derived tissue graft
US5711969A (en) * 1995-04-07 1998-01-27 Purdue Research Foundation Large area submucosal tissue graft constructs
AUPN238795A0 (en) * 1995-04-12 1995-05-11 Hip Developments International Pty Ltd Improved process for knee reconstruction
EP2282540A3 (de) 1995-10-02 2013-05-15 Starsight Telecast, Inc. Vorrichtungen und Verfahren zur bereitstellung von Fernsehprogramminformation
US5865723A (en) * 1995-12-29 1999-02-02 Ramus Medical Technologies Method and apparatus for forming vascular prostheses
EP0877795A4 (de) * 1996-01-16 2003-03-05 Depuy Orthopaedics Inc Isolierung von vorläuferzellen aus hematopoietischen und nicht hematopoietischen gewebe und deren verwendung
US5788625A (en) * 1996-04-05 1998-08-04 Depuy Orthopaedics, Inc. Method of making reconstructive SIS structure for cartilaginous elements in situ
US5755791A (en) * 1996-04-05 1998-05-26 Purdue Research Foundation Perforated submucosal tissue graft constructs
US5718012A (en) * 1996-05-28 1998-02-17 Organogenesis, Inc. Method of strength enhancement of collagen constructs
US6171344B1 (en) 1996-08-16 2001-01-09 Children's Medical Center Corporation Bladder submucosa seeded with cells for tissue reconstruction
ES2197360T3 (es) * 1996-08-16 2004-01-01 The Children's Medical Center Corporation Submucosa vesical sembrada con celulas para la reconstruccion del tejido.
US6666892B2 (en) * 1996-08-23 2003-12-23 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US8716227B2 (en) * 1996-08-23 2014-05-06 Cook Biotech Incorporated Graft prosthesis, materials and methods
ES2208974T3 (es) 1996-08-23 2004-06-16 Cook Biotech, Inc. Protesis de injertos, materiales y metodos.
US20060025786A1 (en) * 1996-08-30 2006-02-02 Verigen Transplantation Service International (Vtsi) Ag Method for autologous transplantation
AU778308B2 (en) * 1996-08-30 2004-11-25 Genzyme Corporation Method, instruments and kit for autologous transplantation
US5881733A (en) * 1996-09-13 1999-03-16 Depuy Orthopaedic Technology, Inc. Technique for osteocartilaginous transplantation in a mammalian joint
US5964805A (en) * 1997-02-12 1999-10-12 Stone; Kevin R. Method and paste for articular cartilage transplantation
ES2213835T3 (es) 1996-09-16 2004-09-01 Purdue Research Foundation Injerto de tejidos intestinales submucosales para la reparacion de tejidos neurologicos.
US7101857B2 (en) * 1996-11-05 2006-09-05 Gp Medical, Inc. Crosslinkable biological material and medical uses
US6545042B2 (en) 1996-11-05 2003-04-08 Gp Medical Acellular biological material chemically treated with genipin
US6998418B1 (en) 1996-11-05 2006-02-14 Gp Medical, Inc. Acellular biological material chemically treated with genipin
JP4046358B2 (ja) 1996-12-10 2008-02-13 パーデュー・リサーチ・ファウンデーション 粘膜下組織抽出物
CA2273250C (en) 1996-12-10 2008-01-29 Cook Biotech, Inc. Stent grafts containing purified submucosa
CA2267310C (en) * 1996-12-10 2012-09-18 Purdue Research Foundation Stomach submucosa derived tissue graft
EP1300154B1 (de) * 1996-12-10 2005-09-14 Purdue Research Foundation Gewebetransplantat aus der Magensubmukosa
EP0942739B1 (de) * 1996-12-10 2006-04-12 Purdue Research Foundation Aus wirbeltierlebergewebe gewonnenes biomaterial
US6696270B2 (en) 1996-12-10 2004-02-24 Purdue Research Foundation Gastric submucosal tissue as a novel diagnostic tool
DK0956028T3 (da) * 1996-12-10 2001-11-05 Methodist Health Group Inc Inhibering af neoplastisk cellevækst med submucosavæv
AU736572B2 (en) 1996-12-10 2001-08-02 Purdue Research Foundation Artificial vascular valves
JP4084420B2 (ja) * 1996-12-10 2008-04-30 パーデュー・リサーチ・ファウンデーション 管状粘膜下組織移植片構成物
US6494904B1 (en) 1996-12-27 2002-12-17 Ramus Medical Technologies Method and apparatus for forming vascular prostheses
US6077217A (en) * 1997-06-25 2000-06-20 Ramus Medical Technologies, Inc. System and method for assembling graft structures
EP1007673B1 (de) 1997-07-30 2008-12-17 Emory University Neue knochenmineralisierungsproteine, dna, vektoren, expressionssysteme
US7923250B2 (en) 1997-07-30 2011-04-12 Warsaw Orthopedic, Inc. Methods of expressing LIM mineralization protein in non-osseous cells
US6110209A (en) * 1997-08-07 2000-08-29 Stone; Kevin R. Method and paste for articular cartilage transplantation
US20010031254A1 (en) * 1998-11-13 2001-10-18 Bianchi John R. Assembled implant
US6482584B1 (en) 1998-11-13 2002-11-19 Regeneration Technologies, Inc. Cyclic implant perfusion cleaning and passivation process
CA2303853C (en) 1997-09-24 2007-01-30 Depuy Orthopaedics, Inc. Acl fixation pin and method
AUPP000797A0 (en) * 1997-10-24 1997-11-20 Cryptych Pty Ltd Fixation of cruciate ligament grafts
EP1042453A4 (de) 1997-12-23 2003-05-21 Purdue Research Foundation Aus follikelbasalmembranen abstammendes biomaterial
US7070607B2 (en) * 1998-01-27 2006-07-04 The Regents Of The University Of California Bioabsorbable polymeric implants and a method of using the same to create occlusions
EP1056836B1 (de) * 1998-02-27 2009-02-18 Purdue Research Foundation Submukosale gel zusammensetzungen
US7452371B2 (en) * 1999-06-02 2008-11-18 Cook Incorporated Implantable vascular device
JP4399585B2 (ja) * 1998-06-02 2010-01-20 クック インコーポレイティド 多辺管内医療器具
ATE423577T1 (de) * 1998-06-05 2009-03-15 Organogenesis Inc Biologisch modellierte implantierbare prothesen
WO1999063051A2 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered flat sheet graft prostheses
DE69940507D1 (de) * 1998-06-05 2009-04-16 Organogenesis Inc Biotechnisch erzeugte gefässprothese für die implantation
MXPA00012063A (es) * 1998-06-05 2003-04-22 Organogenesis Inc Protesis de soporte de injerto vascular biodisenadas.
US6458109B1 (en) * 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
GB2341323A (en) * 1998-09-11 2000-03-15 Royal Veterinary College The Prosthesis
EP1051116B8 (de) 1998-12-01 2009-06-10 Washington University Vorrichtung zur intravaskulären embolisierung
US6918396B1 (en) 1998-12-01 2005-07-19 Purdue Research Foundation Method for vocal cord reconstruction
WO2000032254A1 (en) * 1998-12-01 2000-06-08 Purdue Research Foundation Method for vocal cord reconstruction
CA2319443C (en) * 1998-12-01 2009-09-29 Cook Biotech, Inc. Collagenous biomaterials formed with submucosal tissue
US8882850B2 (en) * 1998-12-01 2014-11-11 Cook Biotech Incorporated Multi-formed collagenous biomaterial medical device
US6287340B1 (en) * 1999-05-14 2001-09-11 Trustees Of Tufts College Bioengineered anterior cruciate ligament
US6964685B2 (en) 1999-06-22 2005-11-15 The Brigham And Women's Hospital, Inc. Biologic replacement for fibrin clot
US6179840B1 (en) 1999-07-23 2001-01-30 Ethicon, Inc. Graft fixation device and method
US20020095157A1 (en) 1999-07-23 2002-07-18 Bowman Steven M. Graft fixation device combination
US20020116063A1 (en) * 1999-08-02 2002-08-22 Bruno Giannetti Kit for chondrocyte cell transplantation
DE60041703D1 (de) * 1999-08-06 2009-04-16 Cook Biotech Inc Rohrförmige transplantatkonstruktion
US6824533B2 (en) 2000-11-29 2004-11-30 Hill-Rom Services, Inc. Wound treatment apparatus
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6579538B1 (en) 1999-12-22 2003-06-17 Acell, Inc. Tissue regenerative compositions for cardiac applications, method of making, and method of use thereof
US6576265B1 (en) * 1999-12-22 2003-06-10 Acell, Inc. Tissue regenerative composition, method of making, and method of use thereof
US20040043006A1 (en) * 2002-08-27 2004-03-04 Badylak Stephen F. Tissue regenerative composition
DK2055325T3 (da) 1999-12-22 2019-09-30 Acell Inc Vævsregenerationssammensætning
US8758400B2 (en) * 2000-01-05 2014-06-24 Integrated Vascular Systems, Inc. Closure system and methods of use
US7842068B2 (en) * 2000-12-07 2010-11-30 Integrated Vascular Systems, Inc. Apparatus and methods for providing tactile feedback while delivering a closure device
US6461364B1 (en) * 2000-01-05 2002-10-08 Integrated Vascular Systems, Inc. Vascular sheath with bioabsorbable puncture site closure apparatus and methods of use
US6391048B1 (en) 2000-01-05 2002-05-21 Integrated Vascular Systems, Inc. Integrated vascular device with puncture site closure component and sealant and methods of use
US9579091B2 (en) * 2000-01-05 2017-02-28 Integrated Vascular Systems, Inc. Closure system and methods of use
US7635390B1 (en) 2000-01-14 2009-12-22 Marctec, Llc Joint replacement component having a modular articulating surface
CA2397746C (en) * 2000-02-03 2010-07-27 Cook Incorporated Implantable vascular device
US7585323B2 (en) * 2000-05-05 2009-09-08 Medlden, Llc In vitro mechanical loading of musculoskeletal tissues
US6645226B1 (en) * 2000-05-19 2003-11-11 Coapt Systems, Inc. Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing
US7156862B2 (en) 2000-05-19 2007-01-02 Coapt Systems, Inc. Multi-point tension distribution system device and method of tissue approximation using that device to improve wound healing
US20010043943A1 (en) * 2000-05-22 2001-11-22 Coffey Arthur C. Combination SIS and vacuum bandage and method
AU2001269936A1 (en) * 2000-06-20 2002-01-02 Phycotransgenics, Llc Transgenic algae for delivering antigens to an animal
US6638312B2 (en) * 2000-08-04 2003-10-28 Depuy Orthopaedics, Inc. Reinforced small intestinal submucosa (SIS)
US8366787B2 (en) 2000-08-04 2013-02-05 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
AU8800801A (en) * 2000-09-08 2002-03-22 James E Coleman Surgical staple
CA2422852C (en) * 2000-09-18 2012-06-26 Organogenesis Inc. Methods for treating a patient using a bioengineered flat sheet graft prostheses
DE10049270B4 (de) 2000-09-28 2005-09-15 Richard Wolf Gmbh Vorrichtung zum Konditionieren eines zu implantierenden Bandes
US6626918B1 (en) * 2000-10-06 2003-09-30 Medical Technology Group Apparatus and methods for positioning a vascular sheath
US6592622B1 (en) 2000-10-24 2003-07-15 Depuy Orthopaedics, Inc. Apparatus and method for securing soft tissue to an artificial prosthesis
AU2002218093A1 (en) * 2000-11-24 2002-06-03 Universite Laval Connective tissue substitutes, method of preparation and uses thereof
US6685681B2 (en) * 2000-11-29 2004-02-03 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6855135B2 (en) * 2000-11-29 2005-02-15 Hill-Rom Services, Inc. Vacuum therapy and cleansing dressing for wounds
US6623510B2 (en) * 2000-12-07 2003-09-23 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
US7905900B2 (en) * 2003-01-30 2011-03-15 Integrated Vascular Systems, Inc. Clip applier and methods of use
US7211101B2 (en) 2000-12-07 2007-05-01 Abbott Vascular Devices Methods for manufacturing a clip and clip
US7806904B2 (en) 2000-12-07 2010-10-05 Integrated Vascular Systems, Inc. Closure device
US6695867B2 (en) 2002-02-21 2004-02-24 Integrated Vascular Systems, Inc. Plunger apparatus and methods for delivering a closure device
US8690910B2 (en) 2000-12-07 2014-04-08 Integrated Vascular Systems, Inc. Closure device and methods for making and using them
CA2365376C (en) * 2000-12-21 2006-03-28 Ethicon, Inc. Use of reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
US6599323B2 (en) * 2000-12-21 2003-07-29 Ethicon, Inc. Reinforced tissue implants and methods of manufacture and use
US6852330B2 (en) * 2000-12-21 2005-02-08 Depuy Mitek, Inc. Reinforced foam implants with enhanced integrity for soft tissue repair and regeneration
EP1392202A4 (de) * 2001-05-07 2009-10-21 Crosscart Inc Submukosale xenotransplantate
WO2002096269A2 (en) * 2001-05-31 2002-12-05 Coapt Systems, Inc. Anterior cruciate ligament reconstruction system
US20050065533A1 (en) * 2001-05-31 2005-03-24 Magen Hugh E. Apparatus for assembling anterior cruciate ligament reconstruction system
US20040153153A1 (en) * 2001-05-31 2004-08-05 Elson Robert J. Anterior cruciate ligament reconstruction system and method of implementing same
IES20010547A2 (en) * 2001-06-07 2002-12-11 Christy Cummins Surgical Staple
US7993365B2 (en) 2001-06-08 2011-08-09 Morris Innovative, Inc. Method and apparatus for sealing access
AU2002310364B2 (en) 2001-06-08 2006-02-23 Morris Innovative Research, Inc. Method and apparatus for sealing access
US20070038244A1 (en) * 2001-06-08 2007-02-15 Morris Edward J Method and apparatus for sealing access
US20060004408A1 (en) * 2001-06-08 2006-01-05 Morris Edward J Method and apparatus for sealing access
DE10128918C2 (de) * 2001-06-15 2003-06-26 Aesculap Ag & Co Kg Implantat zur Fixierung benachbarter Knochenplatten
AU2002320189B2 (en) * 2001-06-28 2007-04-26 Cook Biotech Incorporated Graft prosthesis devices containing renal capsule collagen
US7201917B2 (en) * 2001-07-16 2007-04-10 Depuy Products, Inc. Porous delivery scaffold and method
US7819918B2 (en) * 2001-07-16 2010-10-26 Depuy Products, Inc. Implantable tissue repair device
JP4197159B2 (ja) 2001-07-16 2008-12-17 デピュイ・プロダクツ・インコーポレイテッド 混成の生物学的合成の生体吸収性支持骨格材料
EP1416880B1 (de) 2001-07-16 2011-03-02 DePuy Products, Inc. Gerät zur reparatur von knorpelmaterial
AU2002322567B2 (en) 2001-07-16 2007-09-06 Depuy Products, Inc. Devices form naturally occurring biologically derived
WO2003007787A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Cartilage repair and regeneration device and method
AU2002354911B2 (en) * 2001-07-16 2007-08-30 Depuy Products, Inc. Meniscus regeneration device and method
US8025896B2 (en) * 2001-07-16 2011-09-27 Depuy Products, Inc. Porous extracellular matrix scaffold and method
WO2003007789A2 (en) * 2001-07-16 2003-01-30 Depuy Products, Inc. Porous extracellular matrix scaffold and method
EP1416874A4 (de) * 2001-07-16 2007-04-18 Depuy Products Inc Biologische/synthetische poröse extrazelluläre hybrid-matrixgerüste
AU2002354913B2 (en) * 2001-07-16 2008-07-17 Depuy Products, Inc. Unitary surgical device and method
US7833283B2 (en) * 2001-08-16 2010-11-16 Purdue Research Foundation Material and method for promoting tissue growth
US7622129B1 (en) 2002-08-05 2009-11-24 Purdue Research Foundation Nano-structured polymers for use as implants
US7708741B1 (en) 2001-08-28 2010-05-04 Marctec, Llc Method of preparing bones for knee replacement surgery
WO2003030966A1 (en) * 2001-10-11 2003-04-17 Hill-Rom Services, Inc. Waste container for negative pressure therapy
DE60225824T2 (de) * 2001-10-26 2009-04-16 Cook Biotech, Inc., West Lafayette Medizinisches implantat mit netzartiger struktur
US20030118560A1 (en) * 2001-12-20 2003-06-26 Kelly Sheila J. Composite biocompatible matrices
ATE387919T1 (de) * 2001-12-26 2008-03-15 Hill Rom Services Inc Vakuumbindenverpackung
EP2623138B1 (de) * 2001-12-26 2020-08-05 KCI Licensing, Inc. Gelüfteter Vakuumverband und Verfahren
EP1461113A4 (de) * 2001-12-26 2009-05-06 Hill Rom Services Inc Verbandsset für die wundvakuumtherapie
WO2003059061A1 (en) * 2002-01-11 2003-07-24 Purdue Research Foundation Biomaterial derived from vertebrate liver tissue
US20050171616A1 (en) * 2002-02-04 2005-08-04 Hsing-Wen Sung Peritoneal regeneration with acellular pericardial patch
US20100254900A1 (en) * 2002-03-18 2010-10-07 Campbell Phil G Biocompatible polymers and Methods of use
US8529956B2 (en) * 2002-03-18 2013-09-10 Carnell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
US8168848B2 (en) 2002-04-10 2012-05-01 KCI Medical Resources, Inc. Access openings in vacuum bandage
AU2003231229A1 (en) * 2002-04-30 2003-11-17 Cook Biotech Incorporated Sling for supporting tissue
CN1713861A (zh) * 2002-05-02 2005-12-28 普渡研究基金会 血管化增强的移植构造物
EP1585426A4 (de) * 2002-05-02 2006-09-20 Cook Biotech Inc Mit zellen beimpfte extrazelluläre matrix-transplantate
NZ536564A (en) * 2002-05-02 2008-05-30 Purdue Research Foundation Vascularization enhanced graft constructs which comprise a matrix composition consisting of liver basement membrane
CN1684589A (zh) * 2002-05-02 2005-10-19 普渡研究基金会 血管化增强的移植构造物
JP2005528162A (ja) 2002-06-03 2005-09-22 エヌエムティー メディカル インコーポレイテッド 心臓内欠損閉塞のための生物学的組織足場を有するデバイス
US7850709B2 (en) 2002-06-04 2010-12-14 Abbott Vascular Inc. Blood vessel closure clip and delivery device
US7160326B2 (en) * 2002-06-27 2007-01-09 Depuy Products, Inc. Method and apparatus for implantation of soft tissue implant
US20040166169A1 (en) * 2002-07-15 2004-08-26 Prasanna Malaviya Porous extracellular matrix scaffold and method
US7955388B2 (en) * 2006-11-01 2011-06-07 Acumed Llc Orthopedic connector system
US7550004B2 (en) * 2002-08-20 2009-06-23 Cook Biotech Incorporated Endoluminal device with extracellular matrix material and methods
US7896856B2 (en) 2002-08-21 2011-03-01 Robert Petrosenko Wound packing for preventing wound closure
US7824701B2 (en) 2002-10-18 2010-11-02 Ethicon, Inc. Biocompatible scaffold for ligament or tendon repair
US20040078090A1 (en) 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7682392B2 (en) * 2002-10-30 2010-03-23 Depuy Spine, Inc. Regenerative implants for stabilizing the spine and devices for attachment of said implants
US20040187877A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of liver tissue
US20040191226A1 (en) * 2002-12-04 2004-09-30 Badylak Stephen F. Method for repair of body wall
US7857828B2 (en) * 2003-01-30 2010-12-28 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8821534B2 (en) 2010-12-06 2014-09-02 Integrated Vascular Systems, Inc. Clip applier having improved hemostasis and methods of use
US8202293B2 (en) 2003-01-30 2012-06-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8905937B2 (en) * 2009-02-26 2014-12-09 Integrated Vascular Systems, Inc. Methods and apparatus for locating a surface of a body lumen
US8398656B2 (en) * 2003-01-30 2013-03-19 Integrated Vascular Systems, Inc. Clip applier and methods of use
US8758398B2 (en) 2006-09-08 2014-06-24 Integrated Vascular Systems, Inc. Apparatus and method for delivering a closure element
US8197837B2 (en) 2003-03-07 2012-06-12 Depuy Mitek, Inc. Method of preparation of bioabsorbable porous reinforced tissue implants and implants thereof
US20040175366A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Scaffold for cell growth and differentiation
US20040176855A1 (en) * 2003-03-07 2004-09-09 Acell, Inc. Decellularized liver for repair of tissue and treatment of organ deficiency
WO2004096085A2 (en) * 2003-03-27 2004-11-11 Purdue Research Foundation Nanofibers as a neural biomaterial
US7067123B2 (en) * 2003-04-29 2006-06-27 Musculoskeletal Transplant Foundation Glue for cartilage repair
US7901457B2 (en) * 2003-05-16 2011-03-08 Musculoskeletal Transplant Foundation Cartilage allograft plug
US20090291112A1 (en) * 2003-05-16 2009-11-26 Truncale Katherine G Allograft osteochondral plug combined with cartilage particle mixture
US7105001B2 (en) * 2003-05-21 2006-09-12 Mandelbaum Jon A Surgical method and composition utilizing submucosal tissue to prevent incisional hernias
WO2005002601A1 (en) 2003-06-25 2005-01-13 Badylak Stephen F Conditioned matrix compositions for tissue restoration
US8226715B2 (en) 2003-06-30 2012-07-24 Depuy Mitek, Inc. Scaffold for connective tissue repair
US10583220B2 (en) 2003-08-11 2020-03-10 DePuy Synthes Products, Inc. Method and apparatus for resurfacing an articular surface
GB2424586B (en) 2003-08-25 2008-05-28 Cook Biotech Inc Graft materials containing bioactive substances, and methods for their manufacture
AU2004270239C1 (en) * 2003-09-04 2011-07-07 Cook Biotech Incorporated Extracellular matrix composite materials, and manufacture and use thereof
US7645229B2 (en) * 2003-09-26 2010-01-12 Armstrong David N Instrument and method for endoscopic visualization and treatment of anorectal fistula
US7879102B2 (en) * 2003-09-30 2011-02-01 Depuy Acromed, Inc. Method for treatment of defects in the intervertebral disc
US20050071012A1 (en) * 2003-09-30 2005-03-31 Hassan Serhan Methods and devices to replace spinal disc nucleus pulposus
US7316822B2 (en) * 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
US8389588B2 (en) * 2003-12-04 2013-03-05 Kensey Nash Corporation Bi-phasic compressed porous reinforcement materials suitable for implant
US8133500B2 (en) * 2003-12-04 2012-03-13 Kensey Nash Bvf Technology, Llc Compressed high density fibrous polymers suitable for implant
US7901461B2 (en) 2003-12-05 2011-03-08 Ethicon, Inc. Viable tissue repair implants and methods of use
ATE515245T1 (de) 2003-12-11 2011-07-15 Isto Technologies Inc Teilchenförmiges knorpelsystem
US7476255B2 (en) * 2003-12-30 2009-01-13 Depuy Products, Inc. Soft tissue attachment system and method
CN1909840B (zh) * 2004-01-21 2012-03-21 库克公司 用来闭合瘘管的植入式移植物
WO2005077433A1 (en) * 2004-02-09 2005-08-25 Cook Biotech Incorporated Stent graft devices having collagen coating
US8337545B2 (en) 2004-02-09 2012-12-25 Cook Medical Technologies Llc Woven implantable device
US11395865B2 (en) * 2004-02-09 2022-07-26 DePuy Synthes Products, Inc. Scaffolds with viable tissue
WO2005079675A2 (en) * 2004-02-17 2005-09-01 Cook Biotech Incorporated Medical devices and methods for applying bolster material
US7608092B1 (en) * 2004-02-20 2009-10-27 Biomet Sports Medicince, LLC Method and apparatus for performing meniscus repair
WO2005089411A2 (en) 2004-03-17 2005-09-29 Revivicor, Inc. Tissue products from animals lacking functional alpha 1,3 galactosyl transferase
US7449027B2 (en) * 2004-03-29 2008-11-11 Cook Incorporated Modifying fluid flow in a body vessel lumen to promote intraluminal flow-sensitive processes
CA2560876A1 (en) * 2004-03-29 2005-10-13 Cook Biotech Incorporated Medical graft products with differing regions and methods and systems for producing the same
AU2005231781A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated ECM-based graft material
WO2005096989A1 (en) * 2004-03-31 2005-10-20 Cook Incorporated Graft material and stent graft comprising extra collagen matrix and method of preparation
US8216299B2 (en) * 2004-04-01 2012-07-10 Cook Medical Technologies Llc Method to retract a body vessel wall with remodelable material
US8221780B2 (en) 2004-04-20 2012-07-17 Depuy Mitek, Inc. Nonwoven tissue scaffold
US8657881B2 (en) * 2004-04-20 2014-02-25 Depuy Mitek, Llc Meniscal repair scaffold
US8137686B2 (en) 2004-04-20 2012-03-20 Depuy Mitek, Inc. Nonwoven tissue scaffold
US20050249772A1 (en) * 2004-05-04 2005-11-10 Prasanna Malaviya Hybrid biologic-synthetic bioabsorbable scaffolds
US7569233B2 (en) * 2004-05-04 2009-08-04 Depuy Products, Inc. Hybrid biologic-synthetic bioabsorbable scaffolds
US7407511B2 (en) * 2004-05-13 2008-08-05 Wright Medical Technology Inc Methods and materials for connective tissue repair
IES20040368A2 (en) * 2004-05-25 2005-11-30 James E Coleman Surgical stapler
WO2005118019A1 (en) * 2004-05-28 2005-12-15 Cook Incorporated Implantable bioabsorbable valve support frame
US7819898B2 (en) * 2004-06-09 2010-10-26 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US7500983B1 (en) 2004-06-09 2009-03-10 Biomet Sports Medicine, Llc Apparatus for soft tissue attachment
US7695503B1 (en) 2004-06-09 2010-04-13 Biomet Sports Medicine, Llc Method and apparatus for soft tissue attachment
US8109965B2 (en) 2004-06-09 2012-02-07 Biomet Sports Medicine, LLP Method and apparatus for soft tissue fixation
US20050288796A1 (en) * 2004-06-23 2005-12-29 Hani Awad Native soft tissue matrix for therapeutic applications
US20060009835A1 (en) * 2004-07-07 2006-01-12 Osborne Thomas A Graft, stent graft and method
CA2575240A1 (en) * 2004-07-30 2006-02-09 Cook Biotech Incorporated Graft with increased resistance to enzymatic degradation
US20060029633A1 (en) * 2004-08-03 2006-02-09 Arthrotek, Inc Biological patch for use in medical procedures
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US7837740B2 (en) 2007-01-24 2010-11-23 Musculoskeletal Transplant Foundation Two piece cancellous construct for cartilage repair
US20080220044A1 (en) * 2007-03-06 2008-09-11 Semler Eric J Cancellous construct with support ring for repair of osteochondral defects
US7442206B2 (en) * 2004-10-28 2008-10-28 Cook Incorporated Methods and systems for modifying vascular valves
US7513866B2 (en) * 2004-10-29 2009-04-07 Depuy Products, Inc. Intestine processing device and associated method
US7658751B2 (en) 2006-09-29 2010-02-09 Biomet Sports Medicine, Llc Method for implanting soft tissue
US7909851B2 (en) 2006-02-03 2011-03-22 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US8118836B2 (en) 2004-11-05 2012-02-21 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US9017381B2 (en) 2007-04-10 2015-04-28 Biomet Sports Medicine, Llc Adjustable knotless loops
US8137382B2 (en) 2004-11-05 2012-03-20 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8298262B2 (en) 2006-02-03 2012-10-30 Biomet Sports Medicine, Llc Method for tissue fixation
US8128658B2 (en) 2004-11-05 2012-03-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to bone
US7857830B2 (en) * 2006-02-03 2010-12-28 Biomet Sports Medicine, Llc Soft tissue repair and conduit device
US7905903B2 (en) * 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Method for tissue fixation
US8088130B2 (en) 2006-02-03 2012-01-03 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US7749250B2 (en) 2006-02-03 2010-07-06 Biomet Sports Medicine, Llc Soft tissue repair assembly and associated method
US8361113B2 (en) * 2006-02-03 2013-01-29 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8303604B2 (en) 2004-11-05 2012-11-06 Biomet Sports Medicine, Llc Soft tissue repair device and method
US7905904B2 (en) 2006-02-03 2011-03-15 Biomet Sports Medicine, Llc Soft tissue repair device and associated methods
US20060189993A1 (en) * 2004-11-09 2006-08-24 Arthrotek, Inc. Soft tissue conduit device
US9801708B2 (en) 2004-11-05 2017-10-31 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8840645B2 (en) 2004-11-05 2014-09-23 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8998949B2 (en) * 2004-11-09 2015-04-07 Biomet Sports Medicine, Llc Soft tissue conduit device
US8329202B2 (en) 2004-11-12 2012-12-11 Depuy Products, Inc. System and method for attaching soft tissue to an implant
EP1827527B1 (de) * 2004-12-06 2016-08-24 Cook Incorporated Aufblasbare okklusionsvorrichtungen, verfahern und systeme
US7354627B2 (en) * 2004-12-22 2008-04-08 Depuy Products, Inc. Method for organizing the assembly of collagen fibers and compositions formed therefrom
WO2006074060A2 (en) * 2004-12-30 2006-07-13 Cook Incorporated Inverting occlusion devices and systems
US20060206139A1 (en) * 2005-01-19 2006-09-14 Tekulve Kurt J Vascular occlusion device
US20060257447A1 (en) * 2005-03-09 2006-11-16 Providence Health System Composite graft
US9138445B2 (en) * 2005-03-09 2015-09-22 Cook Biotech Incorporated Medical graft materials with adherent extracellular matrix fibrous mass
WO2006099332A2 (en) * 2005-03-11 2006-09-21 Wake Forest University Health Sciences Production of tissue engineered digits and limbs
JP4975013B2 (ja) 2005-03-11 2012-07-11 ウエイク・フオレスト・ユニバーシテイ・ヘルス・サイエンシズ 組織が工作された心臓弁の製造
WO2006099372A2 (en) * 2005-03-11 2006-09-21 Wake Forest University Health Sciences Tissue engineered blood vessels
US20060204539A1 (en) 2005-03-11 2006-09-14 Anthony Atala Electrospun cell matrices
US20060204445A1 (en) * 2005-03-11 2006-09-14 Anthony Atala Cell scaffold matrices with image contrast agents
EP1863545B1 (de) * 2005-03-19 2015-11-18 Cook Biotech, Inc. Prothetische Implantate mit ECM-Verbundwerkstoff
US8197534B2 (en) 2005-03-31 2012-06-12 Cook Medical Technologies Llc Valve device with inflatable chamber
US20060229670A1 (en) * 2005-04-01 2006-10-12 Bates Brian L Method and a medical closure system for sealing a puncture
WO2007011443A2 (en) * 2005-04-29 2007-01-25 Cook Biotech Incorporated Fistula graft with deformable sheet-form material
CA2833585C (en) * 2005-04-29 2017-06-20 Cook Biotech Incorporated Volumetric grafts for treatment of fistulae and related methods and systems
US20060251702A1 (en) * 2005-05-05 2006-11-09 Cook Biotech Incorporated Implantable materials and methods for inhibiting tissue adhesion formation
US7951198B2 (en) * 2005-05-10 2011-05-31 Acumed Llc Bone connector with pivotable joint
AU2006247317B2 (en) * 2005-05-16 2012-04-05 Purdue Research Foundation Engineered extracellular matrices
JP2008543504A (ja) 2005-06-21 2008-12-04 クック・インコーポレイテッド 瘻孔を閉鎖する移植可能なグラフト
US20060292227A1 (en) * 2005-06-23 2006-12-28 Mcpherson Timothy B Extracellular matrix material particles and methods of preparation
US20060293760A1 (en) * 2005-06-24 2006-12-28 Dedeyne Patrick G Soft tissue implants with improved interfaces
US8926633B2 (en) 2005-06-24 2015-01-06 Abbott Laboratories Apparatus and method for delivering a closure element
US8313497B2 (en) * 2005-07-01 2012-11-20 Abbott Laboratories Clip applier and methods of use
US20080312686A1 (en) * 2005-07-01 2008-12-18 Abbott Laboratories Antimicrobial closure element and closure element applier
US7850985B2 (en) * 2005-07-05 2010-12-14 Cook Biotech Incorporated Tissue augmentation devices and methods
US9271817B2 (en) * 2005-07-05 2016-03-01 Cook Biotech Incorporated Tissue augmentation devices and methods
US7815926B2 (en) * 2005-07-11 2010-10-19 Musculoskeletal Transplant Foundation Implant for articular cartilage repair
US7595062B2 (en) 2005-07-28 2009-09-29 Depuy Products, Inc. Joint resurfacing orthopaedic implant and associated method
WO2007126411A2 (en) 2005-07-28 2007-11-08 Carnegie Mellon University Biocompatible polymers and methods of use
US20070038299A1 (en) * 2005-08-12 2007-02-15 Arthrotek, Inc Multilayer microperforated implant
US9456811B2 (en) * 2005-08-24 2016-10-04 Abbott Vascular Inc. Vascular closure methods and apparatuses
US8920442B2 (en) * 2005-08-24 2014-12-30 Abbott Vascular Inc. Vascular opening edge eversion methods and apparatuses
US20070060895A1 (en) 2005-08-24 2007-03-15 Sibbitt Wilmer L Jr Vascular closure methods and apparatuses
US8771340B2 (en) * 2005-08-25 2014-07-08 Cook Medical Technologies Llc Methods and devices for the endoluminal deployment and securement of prostheses
AU2006282754A1 (en) 2005-08-26 2007-03-01 Zimmer, Inc. Implants and methods for repair, replacement and treatment of joint disease
US8470022B2 (en) * 2005-08-31 2013-06-25 Cook Biotech Incorporated Implantable valve
WO2007028052A2 (en) * 2005-09-01 2007-03-08 Cook Incorporated Attachment of material to an implantable frame by cross-linking
WO2007035778A2 (en) 2005-09-19 2007-03-29 Histogenics Corporation Cell-support matrix and a method for preparation thereof
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US9308252B2 (en) * 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) * 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US20070100352A1 (en) * 2005-10-31 2007-05-03 Deffenbaugh Daren L Cartridge suture anchor delivery device, suture anchor delivery device and associated method
US20070100350A1 (en) * 2005-10-31 2007-05-03 Deffenbaugh Daren L Suture anchor cartridge holder, suture anchor cartridge and associated method
US20070100351A1 (en) * 2005-10-31 2007-05-03 Deffenbaugh Daren L Multiple suture anchor delivery device, suture anchor delivery kit and associated method
US20070112360A1 (en) * 2005-11-15 2007-05-17 Patrick De Deyne Bioprosthetic device
WO2007064819A2 (en) * 2005-12-02 2007-06-07 Cook Incorporated Devices, systems, and methods for occluding a defect
US7815923B2 (en) 2005-12-29 2010-10-19 Cook Biotech Incorporated Implantable graft material
WO2007081530A2 (en) * 2006-01-03 2007-07-19 Med Institute, Inc. Endoluminal medical device for local delivery of cathepsin inhibitors
US20070166396A1 (en) 2006-01-06 2007-07-19 University Of Pittsburgh Extracellular matrix based gastroesophageal junction reinforcement device
US20090306776A1 (en) 2006-01-25 2009-12-10 Children's Medical Center Corporation Methods and procedures for ligament repair
WO2007090150A2 (en) * 2006-01-31 2007-08-09 Cook Biotech Incorporated Fistula grafts and related methods and systems for treating fistulae
US9271713B2 (en) 2006-02-03 2016-03-01 Biomet Sports Medicine, Llc Method and apparatus for tensioning a suture
US8251998B2 (en) 2006-08-16 2012-08-28 Biomet Sports Medicine, Llc Chondral defect repair
US9078644B2 (en) 2006-09-29 2015-07-14 Biomet Sports Medicine, Llc Fracture fixation device
US8597327B2 (en) 2006-02-03 2013-12-03 Biomet Manufacturing, Llc Method and apparatus for sternal closure
US8574235B2 (en) 2006-02-03 2013-11-05 Biomet Sports Medicine, Llc Method for trochanteric reattachment
US11259792B2 (en) 2006-02-03 2022-03-01 Biomet Sports Medicine, Llc Method and apparatus for coupling anatomical features
US8968364B2 (en) 2006-02-03 2015-03-03 Biomet Sports Medicine, Llc Method and apparatus for fixation of an ACL graft
US8936621B2 (en) 2006-02-03 2015-01-20 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US9538998B2 (en) 2006-02-03 2017-01-10 Biomet Sports Medicine, Llc Method and apparatus for fracture fixation
US8652172B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Flexible anchors for tissue fixation
US11311287B2 (en) 2006-02-03 2022-04-26 Biomet Sports Medicine, Llc Method for tissue fixation
US8506597B2 (en) 2011-10-25 2013-08-13 Biomet Sports Medicine, Llc Method and apparatus for interosseous membrane reconstruction
US10517587B2 (en) 2006-02-03 2019-12-31 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US8801783B2 (en) 2006-09-29 2014-08-12 Biomet Sports Medicine, Llc Prosthetic ligament system for knee joint
US8771352B2 (en) 2011-05-17 2014-07-08 Biomet Sports Medicine, Llc Method and apparatus for tibial fixation of an ACL graft
US8562647B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for securing soft tissue to bone
US8652171B2 (en) 2006-02-03 2014-02-18 Biomet Sports Medicine, Llc Method and apparatus for soft tissue fixation
US7959650B2 (en) * 2006-09-29 2011-06-14 Biomet Sports Medicine, Llc Adjustable knotless loops
US9149267B2 (en) 2006-02-03 2015-10-06 Biomet Sports Medicine, Llc Method and apparatus for coupling soft tissue to a bone
US8562645B2 (en) 2006-09-29 2013-10-22 Biomet Sports Medicine, Llc Method and apparatus for forming a self-locking adjustable loop
US7828820B2 (en) * 2006-03-21 2010-11-09 Biomet Sports Medicine, Llc Method and apparatuses for securing suture
US8808310B2 (en) * 2006-04-20 2014-08-19 Integrated Vascular Systems, Inc. Resettable clip applier and reset tools
EP2015707B1 (de) * 2006-05-09 2019-01-23 LifeCell Corporation Verstärktes biologisches gewebe
CA2652138C (en) * 2006-05-16 2016-01-19 Purdue Research Foundation Three dimensional purified collagen matrices
US20070269476A1 (en) * 2006-05-16 2007-11-22 Voytik-Harbin Sherry L Engineered extracellular matrices control stem cell behavior
EP2043531B1 (de) 2006-06-15 2013-01-02 Cook Medical Technologies LLC Systeme und vorrichtungen zur verabreichung einer endoluminalen prothese
AU2007260914B2 (en) * 2006-06-21 2012-11-29 Cook Biotech Incorporated Fistula grafts and related methods and systems useful for treating gastrointestinal fistulae
US8974542B2 (en) 2006-06-27 2015-03-10 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable elastomeric patch for treating cardiac or cardiovascular conditions
US8556930B2 (en) 2006-06-28 2013-10-15 Abbott Laboratories Vessel closure device
WO2008008266A2 (en) * 2006-07-07 2008-01-17 University Of Pittsburgh- Of The Commonwealth System Of Higher Education Biohybrid elastomeric scaffolds and methods of use thereof
WO2008024640A2 (en) * 2006-08-10 2008-02-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biodegradable elastomeric scaffolds containing microintegrated cells
EP2053975A1 (de) * 2006-08-24 2009-05-06 Wilson-Cook Medical Inc. Vorrichtungen und verfahren für fistelverschluss
AU2007297611B2 (en) 2006-09-21 2013-02-07 Purdue Research Foundation Collagen preparation and method of isolation
JP2010509943A (ja) 2006-09-28 2010-04-02 チルドレンズ メディカル センター コーポレーション 組織を修復する方法およびそのためのコラーゲン生成物
US11259794B2 (en) 2006-09-29 2022-03-01 Biomet Sports Medicine, Llc Method for implanting soft tissue
US9918826B2 (en) 2006-09-29 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
US8672969B2 (en) 2006-09-29 2014-03-18 Biomet Sports Medicine, Llc Fracture fixation device
US8500818B2 (en) * 2006-09-29 2013-08-06 Biomet Manufacturing, Llc Knee prosthesis assembly with ligament link
US8529961B2 (en) 2006-10-17 2013-09-10 Carmell Therapeutics Corporation Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom
CA2667214C (en) * 2006-10-23 2015-12-01 Cook Biotech Incorporated Processed ecm materials with enhanced component profiles
US7871440B2 (en) * 2006-12-11 2011-01-18 Depuy Products, Inc. Unitary surgical device and method
US20080154233A1 (en) * 2006-12-20 2008-06-26 Zimmer Orthobiologics, Inc. Apparatus for delivering a biocompatible material to a surgical site and method of using same
US8163549B2 (en) 2006-12-20 2012-04-24 Zimmer Orthobiologics, Inc. Method of obtaining viable small tissue particles and use for tissue repair
US8795384B2 (en) * 2007-01-10 2014-08-05 Cook Biotech Incorporated Implantable devices useful for reinforcing a surgically created stoma
US7875057B2 (en) * 2007-01-19 2011-01-25 Arthrex, Inc. Method and suture-button construct for stabilization of cranial cruciate ligament deficient stifle
US8343536B2 (en) 2007-01-25 2013-01-01 Cook Biotech Incorporated Biofilm-inhibiting medical products
WO2008109407A2 (en) * 2007-03-02 2008-09-12 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Extracellular matrix-derived gels and related methods
US8435551B2 (en) * 2007-03-06 2013-05-07 Musculoskeletal Transplant Foundation Cancellous construct with support ring for repair of osteochondral defects
WO2008124361A2 (en) * 2007-04-06 2008-10-16 Cook Biotech Incorporated Fistula plugs having increased column strength and fistula plug delivery apparatuses and methods
CA2684040C (en) 2007-04-12 2016-12-06 Isto Technologies, Inc. Method of forming an implant using a mold that mimics the shape of the tissue defect site and implant formed therefrom
WO2008134610A1 (en) * 2007-04-27 2008-11-06 Cook Biotech Incorporated Growth factor modified extracellular matrix material and methods for preparation and use thereof
US20080279833A1 (en) * 2007-05-10 2008-11-13 Matheny Robert G Laminate sheet articles for tissue regeneration
US9283302B2 (en) 2011-12-16 2016-03-15 Cormatrix Cardiovascular, Inc. Extracellular matrix encasement structures and methods
JP2010528613A (ja) 2007-05-29 2010-08-26 クリストファー ビー. リード, 多能細胞集団を産生する方法およびその使用
US20090142400A1 (en) * 2007-05-31 2009-06-04 Hiles Michael C Analgesic coated medical product
US8226681B2 (en) * 2007-06-25 2012-07-24 Abbott Laboratories Methods, devices, and apparatus for managing access through tissue
US8535349B2 (en) * 2007-07-02 2013-09-17 Cook Biotech Incorporated Fistula grafts having a deflectable graft body portion
US20090024106A1 (en) * 2007-07-17 2009-01-22 Morris Edward J Method and apparatus for maintaining access
US9113851B2 (en) 2007-08-23 2015-08-25 Cook Biotech Incorporated Fistula plugs and apparatuses and methods for fistula plug delivery
US20090069843A1 (en) * 2007-09-10 2009-03-12 Agnew Charles W Fistula plugs including a hydration resistant component
US20090082816A1 (en) 2007-09-20 2009-03-26 Graham Matthew R Remodelable orthopaedic spacer and method of using the same
WO2009042768A1 (en) * 2007-09-25 2009-04-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Triggerably dissolvable hollow fibers for controlled delivery
US10500309B2 (en) 2007-10-05 2019-12-10 Cook Biotech Incorporated Absorbable adhesives and their formulation for use in medical applications
US20090112238A1 (en) * 2007-10-26 2009-04-30 Vance Products Inc., D/B/A Cook Urological Inc. Fistula brush device
JP5214223B2 (ja) * 2007-11-15 2013-06-19 船井電機株式会社 プロジェクタ
US7846199B2 (en) * 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
WO2009076441A1 (en) * 2007-12-10 2009-06-18 Purdue Research Foundation Collagen-based matrices with stem cells
US8893947B2 (en) * 2007-12-17 2014-11-25 Abbott Laboratories Clip applier and methods of use
US20090157101A1 (en) 2007-12-17 2009-06-18 Abbott Laboratories Tissue closure system and methods of use
US20090157177A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Sewing Ring for a Prosthetic Tissue Valve
US8679176B2 (en) 2007-12-18 2014-03-25 Cormatrix Cardiovascular, Inc Prosthetic tissue valve
US20090157170A1 (en) * 2007-12-18 2009-06-18 Matheny Robert G Trileaflet Semi-Lunar Prosthetic Tissue Valve
US8257434B2 (en) 2007-12-18 2012-09-04 Cormatrix Cardiovascular, Inc. Prosthetic tissue valve
US7841502B2 (en) * 2007-12-18 2010-11-30 Abbott Laboratories Modular clip applier
US20090187215A1 (en) * 2007-12-19 2009-07-23 Abbott Laboratories Methods and apparatus to reduce a dimension of an implantable device in a smaller state
US9283266B2 (en) * 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
EP2259809B1 (de) * 2008-02-29 2016-05-25 Cook Biotech Incorporated Beschichtetes embolisierungsinstrument
CA2717725A1 (en) 2008-03-05 2009-09-11 Musculoskeletal Transplant Foundation Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles
US20100008965A1 (en) * 2008-04-01 2010-01-14 Pavalko Fredrick M Biocompatible medical products having enhanced anti-thrombogenic properties
PL2288376T3 (pl) 2008-04-18 2016-07-29 Collplant Ltd Sposoby generowania i wykorzystywania prokolagenu
US20110184439A1 (en) * 2008-05-09 2011-07-28 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biological Matrix for Cardiac Repair
US9282965B2 (en) 2008-05-16 2016-03-15 Abbott Laboratories Apparatus and methods for engaging tissue
US8114156B2 (en) * 2008-05-30 2012-02-14 Edwin Burton Hatch Flexibly compliant ceramic prosthetic meniscus for the replacement of damaged cartilage in orthopedic surgical repair or reconstruction of hip, knee, ankle, shoulder, elbow, wrist and other anatomical joints
US9295757B2 (en) * 2008-06-10 2016-03-29 Cook Biotech Incorporated Quilted implantable graft
CA2728240C (en) * 2008-06-10 2016-11-15 Cook Biotech Incorporated Quilted implantable graft
US8118832B1 (en) 2008-06-16 2012-02-21 Morris Innovative, Inc. Method and apparatus for sealing access
CA2728553C (en) * 2008-07-01 2016-08-16 Cook Biotech Incorporated Isolated extracellular matrix material including subserous fascia
JP5518066B2 (ja) 2008-07-30 2014-06-11 メシンセス リミテッド 前胃細胞外マトリックス由来の組織スキャフォールド
EP2324064B1 (de) 2008-09-02 2017-11-08 Tautona Group LP Stränge aus hyaluronsäure und/oder derivaten daraus, herstellungsverfahren und verwendung
WO2010037092A1 (en) 2008-09-29 2010-04-01 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Self-regulating device for modulating inflammation
US8398676B2 (en) 2008-10-30 2013-03-19 Abbott Vascular Inc. Closure device
WO2010065843A2 (en) 2008-12-05 2010-06-10 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Biologic scaffold for prevention of pulmonary fibrosis
US8323312B2 (en) * 2008-12-22 2012-12-04 Abbott Laboratories Closure device
US8858594B2 (en) * 2008-12-22 2014-10-14 Abbott Laboratories Curved closure device
US20100179589A1 (en) 2009-01-09 2010-07-15 Abbott Vascular Inc. Rapidly eroding anchor
US9173644B2 (en) 2009-01-09 2015-11-03 Abbott Vascular Inc. Closure devices, systems, and methods
US9089311B2 (en) * 2009-01-09 2015-07-28 Abbott Vascular Inc. Vessel closure devices and methods
US9414820B2 (en) * 2009-01-09 2016-08-16 Abbott Vascular Inc. Closure devices, systems, and methods
US9486191B2 (en) 2009-01-09 2016-11-08 Abbott Vascular, Inc. Closure devices
US20100179591A1 (en) * 2009-01-13 2010-07-15 Saltzman Charles L Patch augmentation of achilles tendon repairs
US20100274362A1 (en) * 2009-01-15 2010-10-28 Avner Yayon Cartilage particle tissue mixtures optionally combined with a cancellous construct
US20100185234A1 (en) * 2009-01-16 2010-07-22 Abbott Vascular Inc. Closure devices, systems, and methods
US20100183523A1 (en) 2009-01-22 2010-07-22 Wagner Richard E Dental composition and method
CA2752899A1 (en) * 2009-02-18 2010-08-26 Cormatrix Cardiovascular, Inc. Compositions and methods for preventing cardiac arrhythmia
WO2010099463A2 (en) * 2009-02-27 2010-09-02 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Joint bioscaffolds
WO2010129162A1 (en) 2009-05-06 2010-11-11 Hansa Medical Products, Inc. Self-adjusting medical device
US8343227B2 (en) 2009-05-28 2013-01-01 Biomet Manufacturing Corp. Knee prosthesis assembly with ligament link
US8652500B2 (en) * 2009-07-22 2014-02-18 Acell, Inc. Particulate tissue graft with components of differing density and methods of making and using the same
US8298586B2 (en) 2009-07-22 2012-10-30 Acell Inc Variable density tissue graft composition
US20110054492A1 (en) 2009-08-26 2011-03-03 Abbott Laboratories Medical device for repairing a fistula
WO2011031827A2 (en) 2009-09-09 2011-03-17 Cook Biotech Incorporated Manufacture of extracellular matrix products using supercritical or near supercritical fluids
US8663086B2 (en) * 2009-09-28 2014-03-04 Cook Biotech Incorporated Medical reinforcement graft
US8716438B2 (en) 2009-10-09 2014-05-06 University of Pittsburgh—of the Commonwealth System of Higher Education Matricryptic ECM peptides for tissue reconstruction
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
US20110150934A1 (en) * 2009-12-18 2011-06-23 University Of Notre Dame Ovarian Tumor Tissue Cell Preparations/Vaccines for the Treatment/Inhibition of Ovarian Tumors and Ovarian Cancer
WO2011087743A2 (en) 2009-12-22 2011-07-21 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Decellularized adipose cell growth scaffold
US8329219B2 (en) * 2009-12-22 2012-12-11 Cook Biotech Incorporated Methods for producing ECM-based biomaterials
WO2011085217A1 (en) * 2010-01-08 2011-07-14 Wake Forest University Health Sciences Tissue expander
US8303624B2 (en) * 2010-03-15 2012-11-06 Abbott Cardiovascular Systems, Inc. Bioabsorbable plug
EP2549954B1 (de) * 2010-03-23 2016-08-17 Boston Scientific Scimed, Inc. Annuloplastievorrichtung
WO2011150328A1 (en) 2010-05-27 2011-12-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Wet-electrospun biodegradable scaffold and uses therefor
WO2011156338A2 (en) 2010-06-07 2011-12-15 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for modeling hepatic inflammation
US8758399B2 (en) 2010-08-02 2014-06-24 Abbott Cardiovascular Systems, Inc. Expandable bioabsorbable plug apparatus and method
US8603116B2 (en) 2010-08-04 2013-12-10 Abbott Cardiovascular Systems, Inc. Closure device with long tines
CA2807762C (en) 2010-08-13 2023-08-08 Wake Forest University Health Sciences Methods for making a tissue engineered muscle repair (temr) construct in vitro for implantation in vivo
US9421307B2 (en) 2010-08-17 2016-08-23 University of Pittsburgh—of the Commonwealth System of Higher Education Biohybrid composite scaffold
EP2608777B1 (de) 2010-08-24 2019-07-24 The Regents of the University of California Zusammensetzungen und verfahren für eine herztherapie
US9149276B2 (en) 2011-03-21 2015-10-06 Abbott Cardiovascular Systems, Inc. Clip and deployment apparatus for tissue closure
US8574296B2 (en) * 2011-03-31 2013-11-05 Biomet Manufacturing Corporation Dual tendon bundle
US10973622B2 (en) 2011-04-25 2021-04-13 Arthrex, Inc. Internal brace for tissue repairs and reinforcements
AU2012262549B2 (en) 2011-05-27 2016-02-11 Cormatrix Cardiovascular, Inc. Extracellular matrix material valve conduit and methods of making thereof
BR112013030482A2 (pt) 2011-05-27 2016-09-27 Cormatrix Cardiovascular Inc método de regeneração de uma válvula atrioventricular e duto de material de matriz extracelular
CA2849987C (en) 2011-09-30 2023-03-14 Wake Forest University Health Sciences Bioscaffolds for formation of motor endplates and other specialized tissue structures
US9357991B2 (en) 2011-11-03 2016-06-07 Biomet Sports Medicine, Llc Method and apparatus for stitching tendons
WO2013071096A1 (en) 2011-11-09 2013-05-16 The General Hospital Corporation Composite tissue graft and materials and methods for its production and use
US9381013B2 (en) 2011-11-10 2016-07-05 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9370350B2 (en) 2011-11-10 2016-06-21 Biomet Sports Medicine, Llc Apparatus for coupling soft tissue to a bone
US9357992B2 (en) 2011-11-10 2016-06-07 Biomet Sports Medicine, Llc Method for coupling soft tissue to a bone
US9332976B2 (en) 2011-11-30 2016-05-10 Abbott Cardiovascular Systems, Inc. Tissue closure device
US9259217B2 (en) 2012-01-03 2016-02-16 Biomet Manufacturing, Llc Suture Button
WO2013116744A1 (en) 2012-02-01 2013-08-08 Children's Medical Center Corporation Biomaterial for articular cartilage maintenance and treatment of arthritis
US10940167B2 (en) 2012-02-10 2021-03-09 Cvdevices, Llc Methods and uses of biological tissues for various stent and other medical applications
US9364209B2 (en) 2012-12-21 2016-06-14 Abbott Cardiovascular Systems, Inc. Articulating suturing device
US20140178343A1 (en) 2012-12-21 2014-06-26 Jian Q. Yao Supports and methods for promoting integration of cartilage tissue explants
EP3798226A1 (de) 2013-02-01 2021-03-31 Children's Medical Center Corporation Collagengerüste
CA2899931C (en) 2013-02-08 2019-01-15 Acell, Inc. Methods of manufacturing bioactive gels from extracellular matrix material
AU2014214700B2 (en) 2013-02-11 2018-01-18 Cook Medical Technologies Llc Expandable support frame and medical device
EP2964162B1 (de) 2013-03-07 2018-01-17 Cook Medical Technologies LLC Intestinale bypass-hülse für gewebeeinwuchs
US9757119B2 (en) 2013-03-08 2017-09-12 Biomet Sports Medicine, Llc Visual aid for identifying suture limbs arthroscopically
US9918827B2 (en) 2013-03-14 2018-03-20 Biomet Sports Medicine, Llc Scaffold for spring ligament repair
AU2014227561C1 (en) 2013-03-15 2017-12-14 Cook Biotech Incorporated ECM implant compositions and methods
US9861662B2 (en) 2013-07-03 2018-01-09 University of Pittsburgh—of the Commonwealth System of Higher Education Bone-derived extra cellular matrix gel
EP3498239B1 (de) 2013-08-01 2021-04-21 Cook Medical Technologies LLC Gewebeanpassungsimplantat
GB2517153A (en) 2013-08-15 2015-02-18 Biomet Uk Healthcare Ltd Ligament assembly
US9878071B2 (en) 2013-10-16 2018-01-30 Purdue Research Foundation Collagen compositions and methods of use
US10092679B2 (en) 2013-10-18 2018-10-09 Wake Forest University Health Sciences Laminous vascular constructs combining cell sheet engineering and electrospinning technologies
US10136886B2 (en) 2013-12-20 2018-11-27 Biomet Sports Medicine, Llc Knotless soft tissue devices and techniques
US10286119B2 (en) 2014-01-24 2019-05-14 University of Pittsburgh—of the Commonwealth System of Higher Education Extracellular matrix mesh coating
KR102624370B1 (ko) 2014-03-21 2024-01-15 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 세포외 기질로부터 유래한 최종 멸균된 하이드로겔의 제조 방법
JP5747098B2 (ja) * 2014-03-27 2015-07-08 京セラメディカル株式会社 人工関節置換術用手術装置
US9615822B2 (en) 2014-05-30 2017-04-11 Biomet Sports Medicine, Llc Insertion tools and method for soft anchor
US9700291B2 (en) 2014-06-03 2017-07-11 Biomet Sports Medicine, Llc Capsule retractor
US9993332B2 (en) 2014-07-09 2018-06-12 Medos International Sarl Systems and methods for ligament graft preparation
EP2988130A1 (de) 2014-08-20 2016-02-24 Eppendorf Ag Verfahren zur Beschichtung eines festen Trägers
US10039543B2 (en) 2014-08-22 2018-08-07 Biomet Sports Medicine, Llc Non-sliding soft anchor
SG10201805035QA (en) * 2014-10-10 2018-07-30 Orthocell Ltd Sutureless repair of soft tissue
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US9955980B2 (en) 2015-02-24 2018-05-01 Biomet Sports Medicine, Llc Anatomic soft tissue repair
WO2016138423A1 (en) 2015-02-27 2016-09-01 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Retrievable self-expanding non-thrombogenic low-profile percutaneous atrioventricular valve prosthesis
JP6974916B2 (ja) 2015-02-27 2021-12-01 ユニバーシティ オブ ピッツバーグ − オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 多弁尖の弁の電気紡績ステントレス製作のための二重構成要素マンドレル
US9974534B2 (en) 2015-03-31 2018-05-22 Biomet Sports Medicine, Llc Suture anchor with soft anchor of electrospun fibers
US11919941B2 (en) 2015-04-21 2024-03-05 Purdue Research Foundation Cell-collagen-silica composites and methods of making and using the same
US10182808B2 (en) 2015-04-23 2019-01-22 DePuy Synthes Products, Inc. Knotless suture anchor guide
ES2873519T3 (es) 2015-09-18 2021-11-03 Univ Pittsburgh Commonwealth Sys Higher Education Matriz extracelular soluble no gelificante con actividad biológica
US10383720B2 (en) 2015-12-22 2019-08-20 DePuy Synthes Products, Inc. Graft preparation system
US20190117837A1 (en) 2016-03-02 2019-04-25 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Matrix bound nanovesicles and their use
WO2017189986A1 (en) 2016-04-28 2017-11-02 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Compositions comprising extracellular matrix of primitive animal species and related methods
WO2018156856A1 (en) 2017-02-23 2018-08-30 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Stentless biopolymer heart valve replacement capable of living tissue regeneration
EP4252842A3 (de) 2017-03-02 2023-10-25 University of Pittsburgh- Of the Commonwealth System of Higher Education Ecm-hydrogel zur behandlung von ösophagealer entzündung
ES2931299T3 (es) 2017-03-02 2022-12-28 Univ Pittsburgh Commonwealth Sys Higher Education Hidrogel de matriz extracelular (ECM) y fracción soluble del mismo para su utilización en el tratamiento del cáncer
US11389569B2 (en) 2017-04-03 2022-07-19 University of Pittsburgh—of the Commonwealth System of Higher Education Biodegradable, porous, thermally responsive injectable hydrogel as soft tissue defect filler
CA3061428A1 (en) 2017-04-25 2018-11-01 Purdue Research Foundation 3-dimensional (3d) tissue-engineered muscle for tissue restoration
EP3618841B1 (de) 2017-05-05 2023-03-22 University of Pittsburgh - of The Commonwealth System of Higher Education Okulare anwendungen von matrixgebundenen vesikeln (mbvs)
US11634716B2 (en) 2017-10-16 2023-04-25 University of Pittsburgh—of the Commonwealth System of Higher Education Genetically modified mesenchymal stem cells for use in cardiovascular prosthetics
JP2022513073A (ja) 2018-11-19 2022-02-07 ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ 生分解性組織置換インプラントおよびその使用
KR20210142003A (ko) 2019-03-13 2021-11-23 유니버시티 오브 피츠버그 - 오브 더 커먼웰쓰 시스템 오브 하이어 에듀케이션 음향 세포외 기질 하이드로겔 및 이의 용도
CN110433341A (zh) * 2019-08-29 2019-11-12 上海白衣缘生物工程有限公司 一种组织修复材料及其制备方法
CN110368526A (zh) * 2019-08-29 2019-10-25 上海白衣缘生物工程有限公司 一种医用去细胞生物材料及其制备方法
US20230135760A1 (en) 2020-03-16 2023-05-04 Biosearch, S.A. Biocomposites comprising probiotics, collagen and bacterial extracellular polysaccharide and uses thereof
US20220023489A1 (en) 2020-07-27 2022-01-27 Cook Biotech Incorporated Adhesive for surgical staple line reinforcement
US11826490B1 (en) 2020-12-29 2023-11-28 Acell, Inc. Extracellular matrix sheet devices with improved mechanical properties and method of making
AU2022282379A1 (en) 2021-05-28 2023-11-30 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells
CA3220602A1 (en) 2021-05-28 2022-12-01 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods to generate macular, central and peripheral retinal pigment epithelial cells

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT261800B (de) * 1966-08-22 1968-05-10 Braun Internat Gmbh B Verfahren zur Herstellung von röhrenförmigen, glatten bzw. mit einem Gewinde versehenen Gewebe-Blutgefäß-Prothesen
US4965178A (en) * 1987-09-12 1990-10-23 Canon Kabushiki Kaisha Optical recording medium
US4902508A (en) * 1988-07-11 1990-02-20 Purdue Research Foundation Tissue graft composition
US4956178A (en) * 1988-07-11 1990-09-11 Purdue Research Foundation Tissue graft composition
US5281422A (en) * 1991-09-24 1994-01-25 Purdue Research Foundation Graft for promoting autogenous tissue growth
US5352463A (en) * 1992-11-13 1994-10-04 Badylak Steven F Tissue graft for surgical reconstruction of a collagenous meniscus and method therefor
US5275826A (en) * 1992-11-13 1994-01-04 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft

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