DE69232007T2 - Abgabesystem für eine wirksubstanz mit verzögerter freisetzung - Google Patents

Abgabesystem für eine wirksubstanz mit verzögerter freisetzung

Info

Publication number
DE69232007T2
DE69232007T2 DE69232007T DE69232007T DE69232007T2 DE 69232007 T2 DE69232007 T2 DE 69232007T2 DE 69232007 T DE69232007 T DE 69232007T DE 69232007 T DE69232007 T DE 69232007T DE 69232007 T2 DE69232007 T2 DE 69232007T2
Authority
DE
Germany
Prior art keywords
delivery system
active substance
delayed release
delayed
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69232007T
Other languages
English (en)
Other versions
DE69232007D1 (de
Inventor
Bruce Mazer
Alan Meyer
Shie-Ming Hwang
Leonard Candler
R Drayer
Andre Daab-Krzykowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE69232007D1 publication Critical patent/DE69232007D1/de
Application granted granted Critical
Publication of DE69232007T2 publication Critical patent/DE69232007T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
DE69232007T 1991-12-31 1992-12-21 Abgabesystem für eine wirksubstanz mit verzögerter freisetzung Expired - Fee Related DE69232007T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/816,412 US5160742A (en) 1991-12-31 1991-12-31 System for delivering an active substance for sustained release
PCT/US1992/011160 WO1993012772A1 (en) 1991-12-31 1992-12-21 System for delivering an active substance for sustained release

Publications (2)

Publication Number Publication Date
DE69232007D1 DE69232007D1 (de) 2001-09-20
DE69232007T2 true DE69232007T2 (de) 2002-04-18

Family

ID=25220519

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232007T Expired - Fee Related DE69232007T2 (de) 1991-12-31 1992-12-21 Abgabesystem für eine wirksubstanz mit verzögerter freisetzung

Country Status (7)

Country Link
US (1) US5160742A (de)
EP (1) EP0619733B1 (de)
AU (1) AU3418993A (de)
CA (1) CA2122592C (de)
DE (1) DE69232007T2 (de)
MX (1) MX9207263A (de)
WO (1) WO1993012772A1 (de)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681585A (en) 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5472712A (en) * 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
SG52402A1 (en) * 1992-12-22 1998-09-28 Univ Cincinnati Oral administration of immunologically active biomolecules and other therapeutic proteins
US5645880A (en) * 1993-07-08 1997-07-08 Mcardle; Blaise Protein-polysaccharide complex composition and method of use
FR2710649A1 (fr) * 1993-09-30 1995-04-07 Germinal Sarl Film polymérique à base de prolamines, son procédé de préparation et ses applications .
EE03305B1 (et) * 1994-07-08 2000-12-15 Astra Aktiebolag Paljuosaline tableteeritud annusvorm I
US5728403A (en) * 1994-10-05 1998-03-17 The Board Of Regents Of The University Of Nebraska Coating technology for taste masking orally administered bitter drugs
US5871751A (en) * 1994-10-12 1999-02-16 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University Renibacterium salmoninarum vaccine and method for its preparation
US6277092B1 (en) 1995-01-13 2001-08-21 Abbott Laboratories Apparatus for altering composition of nutritional product during enteral tube feeding
US5531681A (en) * 1995-01-13 1996-07-02 Abbott Laboratories Apparatus for altering composition of nutritional product during enteral tube feeding
US5531734A (en) * 1995-01-13 1996-07-02 Abbott Laboratories Method of altering composition of nutritional product during enteral tube feeding
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
US5631245A (en) * 1995-06-06 1997-05-20 Biodynamics Pharmaceuticals, Inc. Method for medicating the inflammatory controlling system and adverse inflammatory reactions and for making compounds for treating the pathology of adverse inflammatory reactions
SE9600071D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients I
SE512835C2 (sv) * 1996-01-08 2000-05-22 Astrazeneca Ab Doseringsform innehållande en mångfald enheter alla inneslutande syralabil H+K+ATPas-hämmare
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
SE9600072D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral formulation of two active ingredients II
FR2752732B1 (fr) * 1996-08-28 1998-11-20 Pf Medicament Forme galenique a liberation prolongee de milnacipran
AU8293498A (en) 1997-07-02 1999-01-25 Euro-Celtique S.A. Stabilized sustained release tramadol formulations
AU738512B2 (en) 1997-10-03 2001-09-20 Lavipharm Laboratories, Inc. A prolamine-plant polar lipid composition, its method of preparation and applications thereof
AU1150799A (en) * 1997-10-10 1999-05-03 Yamanouchi Europe B.V. Oral compositions containing a cephalosporin antibiotic
US6080132A (en) * 1998-02-27 2000-06-27 Abbott Laboratories Apparatus for altering characteristics of a fluid
US6309373B1 (en) 1998-08-12 2001-10-30 Abbott Laboratories Apparatus for altering the characteristics of a fluid
US6251432B1 (en) * 1999-07-01 2001-06-26 Abbott Laboratories Sustained release dosage form unit having latex coating and method of making the same
US6395198B1 (en) 1999-10-01 2002-05-28 Mcardle Biaise Anti-caking and anti-dusting composition and corresponding methods
US20020106408A1 (en) * 2000-12-01 2002-08-08 Johnatan Bacon Prolamin-based sustained-release compositions and delayed-onset compositions
CA2519211A1 (en) * 2003-03-17 2004-09-30 Takeda Pharmaceutical Company Limited Release control compositions
KR20120080241A (ko) 2003-06-20 2012-07-16 뉴트리니아 리미티드 생활성 화합물의 보호 방법 및 생활성 성분을 포함하는 조성물
US20050147663A1 (en) * 2003-07-17 2005-07-07 Mohan Mailatur S. Method of treatment for improved bioavailability
RU2375048C2 (ru) * 2003-07-17 2009-12-10 Д-Р Редди'С Лабораторис Инк. Фармацевтическая композиция с набухающим покрытием
US20070122480A1 (en) * 2003-09-29 2007-05-31 Cj Corporation Sustained release formulations
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050226929A1 (en) * 2004-04-12 2005-10-13 Jianbo Xie Controlled release opioid analgesic formulation
DE102004026706A1 (de) * 2004-05-28 2005-12-15 Merck Patent Gmbh Orale Darreichungsform enthaltend probiotische Bakterien
FR2872044B1 (fr) * 2004-06-28 2007-06-29 Flamel Technologies Sa Formulation pharmaceutique a base d'antibiotique sous forme microcapsulaire
AU2005305192A1 (en) * 2004-11-04 2006-05-18 Merck Frosst Canada Ltd Process for granulating particles
US7303766B2 (en) * 2005-02-03 2007-12-04 J.M. Huber Corporation Coated/treated metal silicate absorbent particles
MX2008003213A (es) * 2005-09-09 2008-03-18 Kellog Co Acidos grasos omega-3 encapsulados en recubrimientos de zeina y productos alimenticios que los incorporan.
US20070122477A1 (en) * 2005-10-12 2007-05-31 Cytochroma, Inc. Methods and articles for treating 25-hydroxyvitamin D insufficiency and deficiency
PL1993559T3 (pl) 2006-02-03 2017-01-31 Opko Renal, Llc Leczenie niedoboru i deficytu witaminy d z zastosowaniem 25-hydroksywitaminy d2 i 25-hydroksywitaminy d3
LT2679228T (lt) 2006-06-21 2018-05-10 Opko Ireland Global Holdings, Ltd. Terapija naudojant vitamino d atstatymo agentą ir vitamino d hormoninį pakaitinį agentą
US8765178B2 (en) 2006-07-19 2014-07-01 Watson Laboratories, Inc. Controlled release formulations and associated methods
JP2010525080A (ja) 2007-04-25 2010-07-22 プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー 慢性腎臓病における続発性副甲状腺機能亢進症の安全かつ効果的な治療および予防方法
KR101495578B1 (ko) * 2007-04-25 2015-02-25 사이토크로마 인코포레이티드 비타민 ｄ 부족 및 결핍의 치료 방법
WO2008134512A1 (en) 2007-04-25 2008-11-06 Cytochroma Inc. Oral controlled release compositions comprising vitamin d compound and waxy carrier
JP5647516B2 (ja) * 2007-04-25 2014-12-24 シトクロマ インコーポレイテッド ビタミンｄ療法のための方法および化合物
WO2009041945A1 (en) * 2007-09-28 2009-04-02 Capricorn Pharma Inc. Coated compositions and methods for preparing same
TWI391150B (zh) * 2008-01-22 2013-04-01 Taiwan Biotech Co Ltd 腸溶性長效塗覆芯與藥物劑型及其製造方法
ES2954932T3 (es) 2008-04-02 2023-11-27 Eirgen Pharma Ltd Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados
US9504274B2 (en) * 2009-01-27 2016-11-29 Frito-Lay North America, Inc. Methods of flavor encapsulation and matrix-assisted concentration of aqueous foods and products produced therefrom
US20100310726A1 (en) 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Novel Preparation of an Enteric Release System
US8859003B2 (en) * 2009-06-05 2014-10-14 Intercontinental Great Brands Llc Preparation of an enteric release system
US9968564B2 (en) 2009-06-05 2018-05-15 Intercontinental Great Brands Llc Delivery of functional compounds
US20100307542A1 (en) * 2009-06-05 2010-12-09 Kraft Foods Global Brands Llc Method of Reducing Surface Oil on Encapsulated Material
KR102125424B1 (ko) 2010-03-29 2020-06-22 사이토크로마 인코포레이티드 부갑상선 수준을 낮추기 위한 방법 및 조성물
CA2820751A1 (en) * 2010-12-10 2012-06-14 The Governors Of The University Of Alberta Barley protein microcapsules
US8859005B2 (en) 2012-12-03 2014-10-14 Intercontinental Great Brands Llc Enteric delivery of functional ingredients suitable for hot comestible applications
KR101847947B1 (ko) 2013-03-15 2018-05-28 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 안정화되고 변형된 비타민 ｄ 방출 제형
CR20170085A (es) 2014-08-07 2017-04-25 Opko Ireland Global Holdings Ltd Terapia adjuntiva con 25-hidroxi vitamina d
ES2919874T3 (es) * 2014-09-24 2022-07-28 Vital Beverages Global Inc Composiciones y métodos para el suministro selectivo en el tubo gastrointestinal
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
RS64623B1 (sr) 2016-03-24 2023-10-31 Elgan Pharma Ltd Upotreba insulina za podsticanje pražnjenja želuca
JP7032322B2 (ja) 2016-03-28 2022-03-08 オプコ アイルランド グローバル ホールディングス リミテッド ビタミンｄ治療法
US10849938B2 (en) 2017-09-13 2020-12-01 ZBiotics Company Gene expression system for probiotic microorganisms
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895880A (en) * 1955-05-13 1959-07-21 Smith Kline French Lab Sustained release pharmaceutical product
NO98434A (de) * 1959-04-30
US3117027A (en) * 1960-01-08 1964-01-07 Wisconsin Alumni Res Found Apparatus for coating particles in a fluidized bed
GB935672A (en) * 1960-07-19 1963-09-04 Sterling Drug Inc Sustained release tablet
US3196827A (en) * 1962-11-19 1965-07-27 Wisconsin Alumni Res Found Apparatus for the encapsulation of discrete particles
US3253944A (en) * 1964-01-13 1966-05-31 Wisconsin Alumni Res Found Particle coating process
US3241520A (en) * 1964-10-19 1966-03-22 Wisconsin Alumni Res Found Particle coating apparatus
US3558768A (en) * 1969-12-19 1971-01-26 Sterling Drug Inc Sustained release pharmaceutical compositions
US3802896A (en) * 1972-05-15 1974-04-09 Nutrilite Products Color concentrated base dispersion used in tablet film coating
US3939259A (en) * 1974-05-24 1976-02-17 Anthony Pescetti Coating composition and therapeutic preparation incorporating same
US3996355A (en) * 1975-01-02 1976-12-07 American Home Products Corporation Permanent suspension pharmaceutical dosage form
US4137300A (en) * 1976-08-20 1979-01-30 Ciba-Geigy Corporation Sustained action dosage forms
US4323312A (en) * 1977-08-26 1982-04-06 Werner Glatt Fluidized bed apparatus
US4308251A (en) * 1980-01-11 1981-12-29 Boots Pharmaceuticals, Inc. Controlled release formulations of orally-active medicaments
US4384004A (en) * 1981-06-02 1983-05-17 Warner-Lambert Company Encapsulated APM and method of preparation
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4525339A (en) * 1982-10-15 1985-06-25 Hoffmann-La Roche Inc. Enteric coated oral dosage form
JPS59220175A (ja) * 1983-05-28 1984-12-11 Furointo Sangyo Kk 健康食品のコ−テイング方法
US4876094A (en) * 1984-01-13 1989-10-24 Battelle Development Corporation Controlled release liquid dosage formulation
NZ210785A (en) * 1984-01-13 1987-11-27 Battelle Development Corp Liquid dispersions of layered controlled release dosage forms
JPS60221078A (ja) * 1984-04-18 1985-11-05 Morinaga Milk Ind Co Ltd 有用微生物粉末の粒状製品およびその製造法
JPS61141862A (ja) * 1984-12-17 1986-06-28 Furointo Sangyo Kk 可食性徐放性顆粒
BR8506634A (pt) * 1984-12-20 1986-09-09 Rhone Poulenc Sante Composicoes para o revestimento de aditivos alimentares destinados aos ruminantes e granulados sob forma de microcapsulas assim revestidos
US4892742A (en) * 1985-11-18 1990-01-09 Hoffmann-La Roche Inc. Controlled release compositions with zero order release
JPS62201823A (ja) * 1986-02-28 1987-09-05 Freunt Ind Co Ltd 腸内有用細菌含有物およびその製造方法
CH671155A5 (de) * 1986-08-18 1989-08-15 Clinical Technologies Ass
GB8628728D0 (en) * 1986-12-02 1987-01-07 Euro Celtique Sa Spheroids
JPS63151353A (ja) * 1986-12-15 1988-06-23 Oogawara Kakoki Kk ワツクスコ−テイングマイクロカプセルの製造方法
SE8605515D0 (sv) * 1986-12-22 1986-12-22 Astra Laekemedel Ab A liquid dosage form for oral administration of a pharmaceutically active substance
US4895725A (en) * 1987-08-24 1990-01-23 Clinical Technologies Associates, Inc. Microencapsulation of fish oil
FR2624351B1 (fr) * 1987-12-15 1991-11-22 Rhone Poulenc Sante Compositions degradables par voie enzymatique utilisables pour l'enrobage d'additifs alimentaires destines aux ruminants
FI101344B (fi) * 1988-03-31 1998-06-15 Tanabe Seiyaku Co Menetelmä valmistaa valmiste, josta kontrolloidusti vapautuu farmaseut tisesti aktiivista ainetta
IL92344A0 (en) * 1989-01-04 1990-07-26 Gist Brocades Nv Microencapsulation of bioactive substances in biocompatible polymers,microcapsules obtained and pharmaceutical preparation comprising said microcapsules
US4976968A (en) * 1989-02-24 1990-12-11 Clinical Technologies Associates, Inc. Anhydrous delivery systems for pharmacological agents
US4983402A (en) * 1989-02-24 1991-01-08 Clinical Technologies Associates, Inc. Orally administerable ANF
DE3911903A1 (de) * 1989-04-12 1990-10-18 Bosch Gmbh Robert Verdraengerpumpe zum foerdern eines mediums
US5077053A (en) * 1990-02-12 1991-12-31 Warner-Lambert Company Zein as a moisture barrier for sugarless edible compositions and method for preparing same
IT1246382B (it) * 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
CA2085342A1 (en) * 1990-06-14 1991-12-15 Milton R. Kaplan Stable aqueous drug suspensions

Also Published As

Publication number Publication date
MX9207263A (es) 1993-06-01
DE69232007D1 (de) 2001-09-20
WO1993012772A1 (en) 1993-07-08
EP0619733B1 (de) 2001-08-16
AU3418993A (en) 1993-07-28
CA2122592A1 (en) 1993-07-08
CA2122592C (en) 1997-08-05
EP0619733A1 (de) 1994-10-19
EP0619733A4 (de) 1995-06-07
US5160742A (en) 1992-11-03

Similar Documents

Publication Publication Date Title
DE69232007T2 (de) Abgabesystem für eine wirksubstanz mit verzögerter freisetzung
FI961437A (fi) Vaikuttavan aineen luovuttava systeemi
DK0528310T3 (da) Transportsystem
KR950703831A (ko) 신뢰성있는 메시지 전달 시스템(Reliable Message Delivery System)
BR9105833A (pt) Sistema de contencao para agroquimicos e semelhantes
DE69017595T2 (de) Automatisches Transportsystem.
IT8321957A0 (it) Dispositivo di consegna e di svincolo per oggetti utilitari, come carrelli per bagagli.
MX9204882A (es) Sistema de fijacion para pelicula porosa
BR9003129A (pt) Sistema seringa-agulha auto-inutilizavel para injecoes
NO172112C (no) Transportoer for bruk til reoler
DE69314651T2 (de) Transportsystem
FI903911A0 (fi) Stoppningsanordning foer landfordon.
DE68913060D1 (de) Aufbewahrungs- und Ausgabesystem.
NO910022L (no) Fungizide virkestoffkombinasjoner.
IT9047959A0 (it) Sistema di trasporto bobine.
NL193363B (nl) Transportstelsel.
IT1196282B (it) Dispositivo di consegna e di svincolo di oggetti utilitari,come carrelli per bagagli
NO905404L (no) Transportanordning for anvendelse i roeykehus.
ES1023292Y (es) Banderilla perfeccionada para espectaculos taurinos.
DE69112846D1 (de) Viehfütterungsanlage.
ES1016734Y (es) Estructuracion perfeccionada para expositores frigorificos y similares.
FI894383A (fi) Transportsystem.
ES1014627Y (es) Banderin perfeccionado.
DK109491A (da) Transportsystem
DK43191D0 (da) Transportsystem

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee