DE69231415T2 - Stabilisiertes Substrat für kontrollierte Freigabe mit von einer wässerigen Dispersion eines hydrophobischen Polymers abgeleitete Beschichtung - Google Patents

Stabilisiertes Substrat für kontrollierte Freigabe mit von einer wässerigen Dispersion eines hydrophobischen Polymers abgeleitete Beschichtung

Info

Publication number
DE69231415T2
DE69231415T2 DE69231415T DE69231415T DE69231415T2 DE 69231415 T2 DE69231415 T2 DE 69231415T2 DE 69231415 T DE69231415 T DE 69231415T DE 69231415 T DE69231415 T DE 69231415T DE 69231415 T2 DE69231415 T2 DE 69231415T2
Authority
DE
Germany
Prior art keywords
aqueous dispersion
controlled release
coating derived
hydrophobic polymer
elevated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69231415T
Other languages
English (en)
Other versions
DE69231415D1 (de
Inventor
Benjamin Oshlack
Frank Pedi
Mark Chasin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mundipharma GmbH
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25214195&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69231415(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Application granted granted Critical
Publication of DE69231415D1 publication Critical patent/DE69231415D1/de
Publication of DE69231415T2 publication Critical patent/DE69231415T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
DE69231415T 1991-12-24 1992-04-15 Stabilisiertes Substrat für kontrollierte Freigabe mit von einer wässerigen Dispersion eines hydrophobischen Polymers abgeleitete Beschichtung Expired - Lifetime DE69231415T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/814,111 US5273760A (en) 1991-12-24 1991-12-24 Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer

Publications (2)

Publication Number Publication Date
DE69231415D1 DE69231415D1 (de) 2000-10-12
DE69231415T2 true DE69231415T2 (de) 2001-03-29

Family

ID=25214195

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231415T Expired - Lifetime DE69231415T2 (de) 1991-12-24 1992-04-15 Stabilisiertes Substrat für kontrollierte Freigabe mit von einer wässerigen Dispersion eines hydrophobischen Polymers abgeleitete Beschichtung

Country Status (24)

Country Link
US (1) US5273760A (de)
EP (1) EP0548448B1 (de)
JP (1) JP3061474B2 (de)
KR (1) KR100252188B1 (de)
AT (1) ATE196079T1 (de)
AU (1) AU652871B2 (de)
BR (1) BR9202982A (de)
CA (1) CA2061824C (de)
DE (1) DE69231415T2 (de)
DK (1) DK0548448T3 (de)
EG (1) EG20083A (de)
ES (1) ES2152221T3 (de)
FI (1) FI921548A (de)
GR (1) GR3034951T3 (de)
HK (1) HK1005686A1 (de)
IE (1) IE920795A1 (de)
IL (1) IL101080A (de)
MX (1) MX9200932A (de)
NO (1) NO312577B1 (de)
NZ (1) NZ241660A (de)
PT (1) PT548448E (de)
SG (1) SG44703A1 (de)
YU (1) YU48345B (de)
ZA (1) ZA921366B (de)

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US5273760A (en) 1993-12-28
FI921548A (fi) 1993-06-25
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ATE196079T1 (de) 2000-09-15
JPH07165609A (ja) 1995-06-27
ES2152221T3 (es) 2001-02-01
EG20083A (en) 1997-05-31
YU42792A (sh) 1994-09-09
PT548448E (pt) 2001-03-30
NZ241660A (en) 1993-05-26
CA2061824A1 (en) 1993-06-25
IE920795A1 (en) 1993-06-30
IL101080A0 (en) 1992-11-15
SG44703A1 (en) 1997-12-19
AU3002492A (en) 1993-07-01
HK1005686A1 (en) 1999-01-22
KR930012006A (ko) 1993-07-20
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BR9202982A (pt) 1993-06-29
CA2061824C (en) 1999-04-06
YU48345B (sh) 1998-07-10
AU652871B2 (en) 1994-09-08
IL101080A (en) 1996-12-05
DK0548448T3 (da) 2001-01-22
EP0548448A1 (de) 1993-06-30
ZA921366B (en) 1992-12-30
KR100252188B1 (ko) 2000-05-01
DE69231415D1 (de) 2000-10-12
NO925016L (no) 1993-06-25
JP3061474B2 (ja) 2000-07-10
MX9200932A (es) 1993-06-01

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