DE69231281T2 - Zusammensetzung und verfahren zur ulcusprävention und -behandlung - Google Patents

Zusammensetzung und verfahren zur ulcusprävention und -behandlung

Info

Publication number
DE69231281T2
DE69231281T2 DE69231281T DE69231281T DE69231281T2 DE 69231281 T2 DE69231281 T2 DE 69231281T2 DE 69231281 T DE69231281 T DE 69231281T DE 69231281 T DE69231281 T DE 69231281T DE 69231281 T2 DE69231281 T2 DE 69231281T2
Authority
DE
Germany
Prior art keywords
ulcus
prevention
treatment
composition
ulcus prevention
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69231281T
Other languages
English (en)
Other versions
DE69231281D1 (de
Inventor
Richard C Fuisz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Valeant International Bermuda
Original Assignee
Biovail Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovail Technologies Ltd filed Critical Biovail Technologies Ltd
Publication of DE69231281D1 publication Critical patent/DE69231281D1/de
Application granted granted Critical
Publication of DE69231281T2 publication Critical patent/DE69231281T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/60Salicylic acid; Derivatives thereof
    • A61K31/612Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
DE69231281T 1991-12-17 1992-12-16 Zusammensetzung und verfahren zur ulcusprävention und -behandlung Expired - Lifetime DE69231281T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80859991A 1991-12-17 1991-12-17
PCT/US1992/010978 WO1993011750A1 (en) 1991-12-17 1992-12-16 Ulcer prevention and treatment composition and method

Publications (2)

Publication Number Publication Date
DE69231281D1 DE69231281D1 (de) 2000-08-24
DE69231281T2 true DE69231281T2 (de) 2001-03-01

Family

ID=25199224

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231281T Expired - Lifetime DE69231281T2 (de) 1991-12-17 1992-12-16 Zusammensetzung und verfahren zur ulcusprävention und -behandlung

Country Status (9)

Country Link
US (3) US5622717A (de)
EP (1) EP0661966B1 (de)
JP (1) JP3802555B2 (de)
AU (1) AU3328193A (de)
CA (1) CA2125579C (de)
DE (1) DE69231281T2 (de)
DK (1) DK0661966T3 (de)
PL (1) PL170554B1 (de)
WO (1) WO1993011750A1 (de)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6337082B1 (en) * 1991-10-25 2002-01-08 Biovail Tech Ltd Saccharide-based matrix
CA2095776C (en) * 1992-05-12 2007-07-10 Richard C. Fuisz Rapidly dispersable compositions containing polydextrose
US5380473A (en) * 1992-10-23 1995-01-10 Fuisz Technologies Ltd. Process for making shearform matrix
CA2115808A1 (en) * 1993-02-18 1994-08-19 Richard C. Fuisz Polydextrose product and process
WO1995001784A1 (en) * 1993-07-06 1995-01-19 Merck & Co., Inc. H2 antagonist-sucralfate-antiflatulent combinations
ATE208615T1 (de) * 1993-07-09 2001-11-15 Scherer Corp R P Verfahren zur herstellung von gefriergetrockneten arzneistoffdosierungsformen
IT1264546B1 (it) * 1993-07-30 1996-10-02 Lisapharma Spa Composizione farmaceutica ad attivita' antiacida in forma di sospensione a base di gel di sucralfato
EP0716597A1 (de) * 1993-08-30 1996-06-19 Warner-Lambert Company Tablettenüberzug auf der basis einer schmelzgesponnenen mischung aus einem sacharid und einem polymer
US5567439A (en) * 1994-06-14 1996-10-22 Fuisz Technologies Ltd. Delivery of controlled-release systems(s)
US6020002A (en) * 1994-06-14 2000-02-01 Fuisz Technologies Ltd. Delivery of controlled-release system(s)
DE19500977C2 (de) * 1995-01-14 1999-01-07 Lohmann Therapie Syst Lts Feste Arzneimittelform mit in polymerem Material verteiltem Wirkstoff
AU5123396A (en) * 1995-04-03 1996-10-23 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition containing sucralfate
US5658309A (en) * 1995-05-01 1997-08-19 C. R. Bard, Inc. Guidewire/inflation tube locking apparatus and method of use
EP0952770A4 (de) * 1995-09-07 1999-12-22 Fuisz Technologies Ltd Verfahren um grundsatzliche unlosliche biologische wirksame stoffe biologsich verfugbar zu machen
SE9600070D0 (sv) * 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
AU2068797A (en) * 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
US6482465B1 (en) 1997-06-24 2002-11-19 Biovail Technologies Ltd. Positive hydration method of preparing confectionery and product therefrom
US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6096340A (en) * 1997-11-14 2000-08-01 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US7022683B1 (en) * 1998-05-13 2006-04-04 Carrington Laboratories, Inc. Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
US6733778B1 (en) * 1999-08-27 2004-05-11 Andrx Pharmaceuticals, Inc. Omeprazole formulation
US6627234B1 (en) 1998-12-15 2003-09-30 Wm. Wrigley Jr. Company Method of producing active agent coated chewing gum products
US6531114B1 (en) 1999-04-06 2003-03-11 Wm. Wrigley Jr. Company Sildenafil citrate chewing gum formulations and methods of using the same
US6586023B1 (en) 1998-12-15 2003-07-01 Wm. Wrigley Jr. Company Process for controlling release of active agents from a chewing gum coating and product thereof
EP1181010A4 (de) * 1999-04-06 2003-03-26 Wrigley W M Jun Co Pharmazeutische kaugummiformulierungen
US7935362B2 (en) 1999-04-06 2011-05-03 Wm. Wrigley Jr. Company Over-coated product including consumable center and medicament
US6773716B2 (en) 1999-04-06 2004-08-10 Wm. Wrigley Jr. Company Over-coated chewing gum formulations
GB9910212D0 (en) * 1999-05-05 1999-06-30 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US6569472B1 (en) 2000-09-01 2003-05-27 Wm. Wrigley Jr. Company Coated chewing gum products containing antacid and method of making
US6645535B2 (en) 1999-09-02 2003-11-11 Wm. Wrigley Jr. Company Method of making coated chewing gum products containing various antacids
US6541048B2 (en) 1999-09-02 2003-04-01 Wm. Wrigley Jr. Company Coated chewing gum products containing an acid blocker and process of preparing
US6663849B1 (en) 2000-09-01 2003-12-16 Wm. Wrigley Jr. Company Antacid chewing gum products coated with high viscosity materials
US6491540B1 (en) 1999-09-20 2002-12-10 Jack Barreca Center-filled supplement gum
US9253991B2 (en) 1999-09-20 2016-02-09 Jack Barreca Chewing gum with B vitamins
US9387168B2 (en) 1999-09-20 2016-07-12 Jack Barreca Chewing gum with tomatidine
US6555125B2 (en) * 1999-11-30 2003-04-29 Phillip Campbell Lesion and ulcer medication
US6572900B1 (en) 2000-06-09 2003-06-03 Wm. Wrigley, Jr. Company Method for making coated chewing gum products including a high-intensity sweetener
US6444241B1 (en) 2000-08-30 2002-09-03 Wm. Wrigley Jr. Company Caffeine coated chewing gum product and process of making
US6579545B2 (en) 2000-12-22 2003-06-17 Wm. Wrigley Jr. Company Coated chewing gum products containing an antigas agent
US7494669B2 (en) * 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
US6777000B2 (en) * 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
SE0101379D0 (sv) * 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
FR2826548B1 (fr) * 2001-06-28 2007-01-19 Rhodianyl Particule comprenant une matrice et au moins un agent bioactif, son procede de preparation et ses applications
US20030129186A1 (en) 2001-07-25 2003-07-10 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
US20050096281A1 (en) * 2002-03-01 2005-05-05 Unigen Pharmaceuticals, Inc. Formulation of a mixture of Free-B-Ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
US7108868B2 (en) 2002-03-22 2006-09-19 Unigen Pharmaceuticals, Inc. Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia
US7972632B2 (en) 2003-02-28 2011-07-05 Unigen Pharmaceuticals, Inc. Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors
EP2108370A1 (de) 2002-04-30 2009-10-14 Unigen Pharmaceuticals, Inc. Formulierung einer Mischung aus Flavonoiden mit freiem B-Ring und Flavanen als Therapiemittel
US8034387B2 (en) * 2002-04-30 2011-10-11 Unigen, Inc. Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
US20030232092A1 (en) * 2002-06-14 2003-12-18 Hasenmayer Donald L. Liquid antacid compositions
US6930119B2 (en) * 2002-07-17 2005-08-16 Reliant Pharmaceuticals, Inc. Liquid pharmaceutical composition
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
BRPI0409179A (pt) 2003-04-04 2006-05-02 Unigen Pharmaceuticals Inc formulação de inibidores duplos de ciclooxigenase (cox) e lipoxigenase (lox) para cuidados com a pele de mamìferos
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
US20060094760A1 (en) * 2004-11-04 2006-05-04 Fawzy Abdel A Composition, system and method of treatment of gastrointestinal disorders with nizatidine oral solution
US20060134210A1 (en) * 2004-12-22 2006-06-22 Astrazeneca Ab Solid dosage form comprising proton pump inhibitor and suspension made thereof
AU2006239221C1 (en) 2005-04-28 2012-08-16 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
CN101282734A (zh) * 2005-08-10 2008-10-08 玛雅-生物科技有限公司 用于局部施用的药物递送系统
US20160045457A1 (en) 2005-09-09 2016-02-18 Ousama Rachid Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine
US9877921B2 (en) 2005-09-09 2018-01-30 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
TW200800142A (en) * 2005-09-09 2008-01-01 Univ Manitoba Fast-disintegrating epinephrine tablets for buccal or sublingual administration
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
FR2896156A1 (fr) * 2006-01-17 2007-07-20 Gaetan Terrasse Nouvelle utilisation de la tritoqualine en association avec des substances medicamenteuses antagonistes du recepteur h2 a l'histamine,pour le traitement des maladies inflammatoires digestives
US20070248655A1 (en) * 2006-04-21 2007-10-25 Haley Jeffrey T Lenticular shaped protective mouth sore discs
JP2009538901A (ja) * 2006-06-01 2009-11-12 デクセル ファーマ テクノロジーズ エルティーディー. 複式ユニット製薬的製剤
TW200815048A (en) * 2006-06-05 2008-04-01 Verus Pharmaceuticals Inc Methods for buccal, lingual or sublingual dosing regimens of epinephrine for the treatment of allergic emergencies
TW200817049A (en) * 2006-06-05 2008-04-16 Verus Pharmaceuticals Inc Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
KR20110079641A (ko) 2008-09-09 2011-07-07 아스트라제네카 아베 제약 조성물을 이를 필요로 하는 환자에게 전달하는 방법
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
US9848634B2 (en) 2009-06-30 2017-12-26 Philip Morris Products S.A. Smokeless tobacco product
US20120322884A1 (en) 2010-03-01 2012-12-20 University Of Manitoba Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
JP5759544B2 (ja) 2010-07-02 2015-08-05 ザ プロクター アンド ギャンブルカンパニー 活性剤を送達する方法
BR112013000101A2 (pt) 2010-07-02 2016-05-17 Procter & Gamble filamentos compreendendo mantas de não tecido com agente ativo e métodos de fabricação dos mesmos
EP2588654B1 (de) 2010-07-02 2019-08-07 The Procter and Gamble Company Vliesstoff enthaltend einen oder mehrere wirkstoffe
AU2011272839B2 (en) 2010-07-02 2015-04-02 The Procter & Gamble Company Methods of delivering a health care active by administering personal health care articles comprising a filament
ES2560218T3 (es) 2010-07-02 2016-02-17 The Procter & Gamble Company Proceso para fabricar películas a partir de bandas de material no tejido
EP2753321B1 (de) 2011-10-21 2021-12-15 Nova Southeastern University Epinephrinnanopartikel, herstellungsverfahren dafür und verfahren zur verwendung davon zur behandlung von leiden als reaktion auf epinephrin
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту
CA3169368A1 (en) 2012-06-15 2014-01-09 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
PL2976072T3 (pl) 2013-03-22 2021-11-22 Nova Southeastern University Drobne cząstki epinefryny i sposoby ich stosowania do leczenia chorób reagujących na epinefrynę
WO2015076294A1 (ja) * 2013-11-22 2015-05-28 キユーピー株式会社 薬剤の副作用である胃潰瘍の発症抑制方法、および胃潰瘍発症が抑制された経口薬剤組成物ならびにその製造方法
CN105362269A (zh) * 2014-09-01 2016-03-02 天津药物研究院 一种含蔗糖的罗氟司特片及其制备方法
US20170042806A1 (en) 2015-04-29 2017-02-16 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
EA202090637A1 (ru) 2017-09-08 2020-06-29 Инсайгнис Терапьютикс, Инк. Способы применения дипивефрина
CA3087583C (en) 2018-01-26 2024-01-09 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
JP7127135B2 (ja) 2018-01-26 2022-08-29 ザ プロクター アンド ギャンブル カンパニー 水溶性物品及び関連プロセス
JP7110355B2 (ja) 2018-01-26 2022-08-01 ザ プロクター アンド ギャンブル カンパニー 酵素を含む水溶性単位用量物品
WO2019147532A1 (en) 2018-01-26 2019-08-01 The Procter & Gamble Company Water-soluble unit dose articles comprising perfume
WO2019168829A1 (en) 2018-02-27 2019-09-06 The Procter & Gamble Company A consumer product comprising a flat package containing unit dose articles
US10982176B2 (en) 2018-07-27 2021-04-20 The Procter & Gamble Company Process of laundering fabrics using a water-soluble unit dose article
CN113748195B (zh) 2019-01-28 2024-01-19 宝洁公司 可回收利用的、可再生的或可生物降解的包装
WO2020180608A1 (en) 2019-03-01 2020-09-10 Insignis Therapeutics, Inc. Dipivefrin orally disintegrating tablet formulations
EP3712237A1 (de) 2019-03-19 2020-09-23 The Procter & Gamble Company Faserige wasserlösliche einmal-dosierartikel mit wasserlöslichen faserstrukturen
BR112021023244A2 (pt) 2019-06-28 2022-01-04 Procter & Gamble Artigos fibrosos sólidos dissolvíveis contendo tensoativos aniônicos
EP4188554A1 (de) 2020-07-31 2023-06-07 The Procter & Gamble Company Wasserlöslicher faserbeutel mit perlen zur haarpflege

Family Cites Families (147)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118397A (en) * 1964-01-21 Candy making machine
US3118396A (en) * 1964-01-21 Machine for making candy
US3125967A (en) * 1964-03-24 Controls for candy cotton machine
US816055A (en) * 1904-10-11 1906-03-27 Electric Candy Machine Company Centrifugal melting device.
US796528A (en) * 1905-04-10 1905-08-08 Ralph E Pollock Candy-spinning machine.
US856424A (en) * 1905-09-06 1907-06-11 Gen Electric Controlling an electric candy-spinning machine.
US847366A (en) * 1906-06-13 1907-03-19 Ralph E Pollock Candy-spinning machine.
US1489342A (en) * 1922-05-29 1924-04-08 George E Brent Candy machine
US1541378A (en) * 1924-02-16 1925-06-09 Parcell John Confection apparatus
US2826169A (en) * 1954-01-21 1958-03-11 Veen Harry H Le Reflective heat insulating coating for animals
US2918404A (en) * 1956-07-30 1959-12-22 Ortho Pharma Corp Solid compressed amino acid spermicidal vehicle
US3067743A (en) * 1958-11-12 1962-12-11 Alginate Ind Ltd Alginic compounds
US3131428A (en) * 1958-12-19 1964-05-05 Celanese Corp Spinneret and spinning method
US3036532A (en) * 1960-06-28 1962-05-29 Bowe John Cotton candy machine with product of alternating colors
US3019745A (en) * 1960-10-03 1962-02-06 Bois Albert Du Sugar spinning machine
US3070045A (en) * 1961-04-24 1962-12-25 Bowe John Machine for spinning sugar
US3073262A (en) * 1961-08-16 1963-01-15 Bowe John Spinner head for candy cotton machine
NL287733A (de) * 1962-01-15
US3095258A (en) * 1962-06-22 1963-06-25 Du Pont Melt spinning process for producing hollow-core filament
US3308221A (en) * 1963-05-14 1967-03-07 Allied Chem Melt spinning of modified cross section yarn
US3482998A (en) * 1966-02-17 1969-12-09 Gen Mills Inc Process for preparing ground meat composition
US3766165A (en) * 1966-08-17 1973-10-16 Pfizer Polysaccharides and their preparation
US3595675A (en) * 1966-11-21 1971-07-27 Gen Mills Inc Gelatin composition
US3615671A (en) * 1968-04-19 1971-10-26 Gen Foods Corp Dry food products in spun filaments and method of making same
US3557717A (en) * 1968-05-17 1971-01-26 Gen Mills Inc Process for making candy floss
US3723134A (en) * 1968-05-17 1973-03-27 Gen Mills Inc Process for making candy floss
US3557718A (en) * 1968-05-17 1971-01-26 Gen Mills Inc Process for coating cereal with candy floss
US3762846A (en) * 1968-05-17 1973-10-02 Gen Mills Inc Process and apparatus for making candy floss
CH489211A (fr) * 1968-07-09 1970-04-30 Nestle Sa Procédé de fabrication d'un chocolat thermorésistant
US3523889A (en) * 1968-11-26 1970-08-11 American Sugar Method and apparatus for separating liquids from solids
US3676148A (en) * 1970-05-13 1972-07-11 Scm Corp Edible comestibles and process for making same
US3625214A (en) * 1970-05-18 1971-12-07 Alza Corp Drug-delivery device
US3686000A (en) * 1971-01-11 1972-08-22 Gen Foods Corp Moisture resistant sugar filaments
BE785666A (fr) * 1971-07-01 1973-01-02 Procter & Gamble Procede pour la production de compositions enzymatiques en granules
US3951821A (en) * 1972-07-14 1976-04-20 The Dow Chemical Company Disintegrating agent for tablets
US3875300A (en) * 1972-12-18 1975-04-01 Ortho Pharma Corp Composition for sustained release of a medicament and method of using same
US3876794A (en) * 1972-12-20 1975-04-08 Pfizer Dietetic foods
US4186251A (en) * 1973-03-01 1980-01-29 Miles Laboratories, Inc. Composition and method for determination of cholesterol
US3991766A (en) * 1973-05-31 1976-11-16 American Cyanamid Company Controlled release of medicaments using polymers from glycolic acid
US3930043A (en) * 1973-07-19 1975-12-30 Tec Pak Corp Method for making cotton candy
US3856443A (en) * 1973-08-06 1974-12-24 Gen Properties Anstalt Apparatus for producing candyfloss
US3925525A (en) * 1973-08-10 1975-12-09 Celanese Corp Spinning method
US4004039A (en) * 1973-12-03 1977-01-18 General Foods Corporation Sweetening composition and process therefor
US4164448A (en) * 1973-12-07 1979-08-14 Boehringer Mannheim Gmbh Activation of cholesterol oxidase for cholesterol assay
GB1460614A (en) * 1974-04-16 1977-01-06 Tate & Lyle Ltd Production of crystalline sugar
US4072658A (en) * 1974-05-18 1978-02-07 Kanebo, Ltd. Novel phosphorus- and bromine-containing polymers
US4136145A (en) * 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
US3981739A (en) * 1974-08-30 1976-09-21 Amstar Corporation Continuous crystallization
US4056364A (en) * 1974-08-30 1977-11-01 Amstar Corporation Two stage continuous crystallization apparatus with controls
US3967623A (en) * 1975-06-30 1976-07-06 Johnson & Johnson Disposable absorbent pad
US3992265A (en) * 1975-12-31 1976-11-16 American Cyanamid Company Antibiotic susceptibility testing
US4090920A (en) * 1976-02-19 1978-05-23 Fisher Scientific Company Disposable antibiotic susceptability test package
US4086418A (en) * 1976-02-27 1978-04-25 International Telephone And Telegraph Corporation Process for producing a regenerated hollow cellulosic fiber
US4153512A (en) * 1976-04-07 1979-05-08 Fisher Scientific Company Storage stable antibiotic susceptibility test kit and method of testing
GB1581331A (en) * 1976-05-03 1980-12-10 Grindstedvaerket As Bread and other farinaceous products
DE2625834B2 (de) * 1976-06-09 1978-10-12 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Bestimmung von Substraten oder Enzymaktivitäten
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
US4166005A (en) * 1976-12-10 1979-08-28 Eastman Kodak Company Process for the production of α-glycerophosphate oxidase
USRE32016E (en) * 1976-12-10 1985-10-29 Eastman Kodak Company Analysis of lactic acid or lactate using lactate oxidase
US4241178A (en) * 1978-01-06 1980-12-23 Eastman Kodak Company Process and composition for the quantification of glycerol ATP and triglycerides
US4194063A (en) * 1978-02-24 1980-03-18 Eastman Kodak Company Method, composition and elements for the detecting of nitrogen-containing compounds
US4159210A (en) * 1978-06-15 1979-06-26 Amstar Corporation Maple sugar product and method of preparing and using same
US4293570A (en) * 1979-04-02 1981-10-06 Chimicasa Gmbh Process for the preparation of sweetener containing product
US4199373A (en) * 1979-04-13 1980-04-22 Chimicasa Gmbh Process for the manufacture of crystalline fructose
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US4293292A (en) * 1979-11-19 1981-10-06 North Eastern Timber (U.S.A.) Incorporated Candy floss machine
US4271199A (en) * 1979-11-23 1981-06-02 Life Savers, Inc. Sugar-containing chewing gum having smooth texture and long-lasting sweetness
FR2474506B1 (fr) * 1980-01-28 1985-11-22 House Food Industrial Co Granules poreux de saccharide et leur procede de preparation
US4303684A (en) * 1980-03-17 1981-12-01 General Foods Corporation Rapidly-soluble sweetener, process for its preparation and beverage mix employing it
US4348420A (en) * 1980-08-25 1982-09-07 Nutrisearch Company Process for binding comminuted meat
US4338350A (en) * 1980-10-22 1982-07-06 Amstar Corporation Crystallized, readily water-dispersible sugar product
US4362757A (en) * 1980-10-22 1982-12-07 Amstar Corporation Crystallized, readily water dispersible sugar product containing heat sensitive, acidic or high invert sugar substances
US4500546A (en) * 1980-10-31 1985-02-19 International Telephone And Telegraph Corporation Suspensions containing microfibrillated cellulose
US4585797A (en) * 1981-04-13 1986-04-29 Seton Company Cosmetic and pharmaceutical sheet material containing polypeptides
US4376743A (en) * 1981-06-12 1983-03-15 Fiber Industries, Inc. Melt spinning process
US4335232A (en) * 1981-07-07 1982-06-15 E. I. Du Pont De Nemours And Company Optically anisotropic melt forming polyesters
EP0078430B2 (de) * 1981-10-29 1993-02-10 Bayer Ag Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen
US4382963A (en) * 1981-11-09 1983-05-10 General Foods Corporation Low-calorie, sugar-free chewing gum containing polydextrose
US4501538A (en) * 1982-06-17 1985-02-26 Bray Carl R Cotton candy accessory for blender
US4504509A (en) * 1982-07-28 1985-03-12 National Starch & Chem. Corp. Liquid batter for coating foodstuffs and method of making same
JPS5966841A (ja) * 1982-10-05 1984-04-16 Meiji Seika Kaisha Ltd 複合繊維状チユ−インガムの製造方法
US4853243A (en) * 1982-11-04 1989-08-01 Rich Products Corp. Freezer stable whipped ice cream and milk shake food products
GB2137470B (en) * 1983-04-08 1986-11-26 Meiji Seika Kaisha Fleecy confectionery producing machine
US4511584A (en) * 1983-05-31 1985-04-16 Scm Corporation Particulate food acidulant
IT1212778B (it) * 1983-10-07 1989-11-30 Lisapharma Spa Composizioni farmaceutiche adattivita' antiinfiammatoria e/o analgesica, non ulcerogene.
US5104674A (en) * 1983-12-30 1992-04-14 Kraft General Foods, Inc. Microfragmented ionic polysaccharide/protein complex dispersions
EP0169893A4 (de) * 1984-01-31 1987-01-22 Scm Corp Einkapselmatrizenzusammensetzung und diese enthaltendes eingekapseltes erzeugnis.
GB8406734D0 (en) * 1984-03-15 1984-04-18 Tate & Lyle Plc Sugar process
DE3430809A1 (de) * 1984-08-22 1986-03-06 Merck Patent Gmbh, 6100 Darmstadt Sucralfat-suspension
US4581234A (en) * 1984-08-27 1986-04-08 Warner-Lambert Company Non-staling, substantially moistureless chewing gum compositions and improved method of preparation
US4797288A (en) * 1984-10-05 1989-01-10 Warner-Lambert Company Novel drug delivery system
EP0181610A3 (de) * 1984-11-09 1987-11-04 Sumitomo Chemical Company, Limited Schmelzspinnverfahren für aromatische Polyester
US4619833A (en) * 1984-12-13 1986-10-28 General Foods Inc. Process for producing a rapidly water-soluble, free-flowing, sugar-free dry beverage mix
US4816283A (en) * 1984-12-13 1989-03-28 Olympus Industries, Inc. Fruit juice mix for whipped and/or frozen applications
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4684534A (en) * 1985-02-19 1987-08-04 Dynagram Corporation Of America Quick-liquifying, chewable tablet
US4846643A (en) * 1985-10-31 1989-07-11 Toshiba Electric Appliances Apparatus for making cotton candy
US4879108A (en) * 1985-12-20 1989-11-07 Warner-Lambert Company Confectionery delivery system for antipyretics
GB8607717D0 (en) * 1986-03-27 1986-04-30 Unilever Plc Hydratable powders
US4765991A (en) * 1986-05-02 1988-08-23 Warner-Lambert Company Reduced calorie chewing gums and method
US4772477A (en) * 1986-10-17 1988-09-20 Balchem Corporation Meat acidulant
US4793782A (en) * 1986-12-17 1988-12-27 Sells-Floto Inc. Cotton candy machine
US4722845A (en) * 1986-12-23 1988-02-02 Warner-Lambert Company Stable cinnamon-flavored chewing gum composition
US4931293A (en) * 1986-12-23 1990-06-05 Warner-Lambert Company Food acid delivery systems containing polyvinyl acetate
US4981698A (en) * 1986-12-23 1991-01-01 Warner-Lambert Co. Multiple encapsulated sweetener delivery system and method of preparation
US4872821A (en) * 1987-03-23 1989-10-10 Gold Medal Products Co. Cotton candy machine
US4855326A (en) * 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
US5236734A (en) * 1987-04-20 1993-08-17 Fuisz Technologies Ltd. Method of preparing a proteinaceous food product containing a melt spun oleaginous matrix
US5034421A (en) * 1988-12-13 1991-07-23 Fuisz Pharmaceutical Ltd. Moderated spun fibrous system and method of manufacture
US4997856A (en) * 1987-04-20 1991-03-05 Fuisz Pharmaceutical Ltd. Method of producing compacted dispersable systems
US5238696A (en) * 1987-04-20 1993-08-24 Fuisz Technologies Ltd. Method of preparing a frozen comestible
US5011532A (en) * 1988-03-18 1991-04-30 Fuisz Pharmaceutical Ltd. Dispersed systems and method of manufacture
US5096492A (en) * 1987-04-20 1992-03-17 Fuisz Technologies Ltd. Dispersed systems and method of manufacture
US5028632A (en) * 1987-04-20 1991-07-02 Fuisz Pharmaceutical Ltd. Taste masked medicated pharmaceutical
US4873085A (en) * 1987-04-20 1989-10-10 Fuisz Pharmaceutical Ltd. Spun fibrous cosmetic and method of use
US5066218A (en) * 1987-05-13 1991-11-19 Genencor International, Inc. Composition of a steeped starched-containing grain and a cellulase enzyme
JPS63314539A (ja) * 1987-06-17 1988-12-22 Fuji Photo Film Co Ltd 感光材料
US4867986A (en) * 1987-07-17 1989-09-19 Pharmachem Laboratories, Inc. Dry stabilized microemulsified omega-three acid-containing oils
US5041377A (en) * 1988-03-18 1991-08-20 Genencor International Inc. Subtilisin crystallization process
US5081157A (en) * 1988-05-02 1992-01-14 Zila Pharmaceuticals, Inc. Compositions and in situ methods for forming films on body tissue
US5039446A (en) * 1988-07-01 1991-08-13 Genencor International, Inc. Liquid detergent with stabilized enzyme
US5057328A (en) * 1988-11-14 1991-10-15 Warner-Lambert Company Food acid delivery systems containing polyvinyl acetate
US4900563A (en) * 1988-12-29 1990-02-13 Warner-Lambert Company Fructose sweetened chewing gum compositions
US5089606A (en) * 1989-01-24 1992-02-18 Minnesota Mining And Manufacturing Company Water-insoluble polysaccharide hydrogel foam for medical applications
US5079027A (en) * 1989-01-30 1992-01-07 Procter & Gamble Company Nut butter and nut solid milling process
US4988529A (en) * 1989-03-24 1991-01-29 Nissei Kabushiki Kaisha Milk shake and manufacturing method thereof
US4978537A (en) * 1989-04-19 1990-12-18 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
US5169658A (en) * 1989-04-19 1992-12-08 Wm. Wrigley Jr. Company Polyvinyl acetate encapsulation of crystalline sucralose for use in chewing gum
US5037662A (en) * 1989-06-23 1991-08-06 Genencor International Inc. Enzyme assisted degradation of surface membranes of harvested fruits and vegetables
US5009893A (en) * 1989-07-17 1991-04-23 Warner-Lambert Company Breath-freshening edible compositions of methol and a carboxamide
US5094872A (en) * 1989-07-19 1992-03-10 American Maize-Products Company Method for making a reduced fat product
US5009900A (en) * 1989-10-02 1991-04-23 Nabisco Brands, Inc. Glassy matrices containing volatile and/or labile components, and processes for preparation and use thereof
US5204118A (en) * 1989-11-02 1993-04-20 Mcneil-Ppc, Inc. Pharmaceutical compositions and methods for treating the symptoms of overindulgence
US5110614A (en) * 1989-12-14 1992-05-05 Microgold Process of making a microwaveable bakery product
US5073387A (en) * 1990-01-24 1991-12-17 Lafayette Applied Chemistry, Inc. Method for preparing reduced calorie foods
US5084295A (en) * 1990-02-02 1992-01-28 The Procter & Gamble Company Process for making low calorie fat-containing frozen dessert products having smooth, creamy, nongritty mouthfeel
US5082684A (en) * 1990-02-05 1992-01-21 Pfizer Inc. Low-calorie fat substitute
EP0489898A4 (en) * 1990-06-01 1993-06-09 Research Corporation Technologies, Inc. Self-emulsifying glasses
US5077076A (en) * 1990-06-15 1991-12-31 Kraft General Foods, Inc. Low-fat frozen whipped topping and process therefore
US5082682A (en) * 1990-11-09 1992-01-21 Fantasy Flavors, Inc. Nonfat frozen dairy dessert with method and premix therefor
US5196199A (en) * 1990-12-14 1993-03-23 Fuisz Technologies Ltd. Hydrophilic form of perfluoro compounds and method of manufacture
US5171589A (en) * 1991-05-31 1992-12-15 Wm. Wrigley Jr. Company Coated chewing gun products polished with colored wax and method of preparation
US5169657A (en) * 1991-07-17 1992-12-08 Wm. Wrigley Jr. Company Polyvinyl acetate encapsulation of sucralose from solutions for use in chewing gum
US5173322A (en) * 1991-09-16 1992-12-22 Nestec S.A. Reformed casein micelles
US5164210A (en) * 1991-10-08 1992-11-17 Wm. Wrigley Jr. Company Zein/shellac encapsulation of high intensity sweeteners in chewing gum
US5175009A (en) * 1991-10-17 1992-12-29 Wm. Wrigley Jr. Company Stabilized chewing gum containing acidified humectant
US5173317A (en) * 1991-10-29 1992-12-22 Wm. Wrigley Jr. Company Gum compositions containing vinyl laurate/vinyl acetate copolymer

Also Published As

Publication number Publication date
EP0661966B1 (de) 2000-07-19
JPH07502276A (ja) 1995-03-09
US5811123A (en) 1998-09-22
AU3328193A (en) 1993-07-19
WO1993011750A1 (en) 1993-06-24
US5622717A (en) 1997-04-22
DE69231281D1 (de) 2000-08-24
US5651987A (en) 1997-07-29
CA2125579A1 (en) 1993-06-24
PL170554B1 (pl) 1996-12-31
CA2125579C (en) 2005-06-21
EP0661966A4 (de) 1996-02-28
JP3802555B2 (ja) 2006-07-26
EP0661966A1 (de) 1995-07-12
DK0661966T3 (da) 2000-10-16

Similar Documents

Publication Publication Date Title
DE69231281T2 (de) Zusammensetzung und verfahren zur ulcusprävention und -behandlung
DE69329461D1 (de) Verfahren zur extraktion und reinigung von hamoglobin
DE69316810D1 (de) SiGe-SOI-MOSFET und Verfahren zur Herstellung
DE69329670T2 (de) Verfahren und Gerät zur Rauschminderung
DE69218536D1 (de) Verfahren und Gerät zur Spektrenvergleichung
DE69415665T2 (de) Verfahren und gerät zur stereophonen wiedergabe
DE69332446D1 (de) Verfahren zur Kontrolle des Staubens und damit erhaltene Zusammensetzungen
DE69222735D1 (de) Zusammensetzung und Verfahren zur Behandlung von Kühlwasser
DE69330620D1 (de) Verfahren und Einrichtung zur Bildkodierung
DE69435047D1 (de) Schaltung und Verfahren zur parallelen Addition und Mittelwertbildung
DE69231592D1 (de) Verfahren und zusammensetzungen zur behandlung von malaria und anderen erkrankungen
DE69423072T2 (de) Kodierer und verfahren zur kodierung
DE69602847D1 (de) Tuberkilizide synergistische desinfizierende zusammensetzung und verfahren zur desinfektion
DE69318568T2 (de) Zusammensetzungen zur entfernung von aldehyden und verfahren
DE69329439T2 (de) Verfahren und Einrichtung zur Kodierung
DE19581575T1 (de) Verfahren und Zusammensetzung zur Bekämpfung der Umweltverschmutzung
DE69100870T2 (de) Verfahren und Zusammensetzung zur Verhinderung der Kesselsteinbildung.
DE69128406D1 (de) Lateraler MOSFET und Verfahren zur Herstellung
DE69324072T2 (de) Verfahren zur Oberflächenbehandlung
DE69030584T2 (de) Verfahren sowie zusammensetzungen zur behandlung mit vitaminmineral
DE69317968D1 (de) Verfahren und Einrichtung zur Störungsunterdrückung
DE69219197T2 (de) Zusammensetzung zur Schmerzlinderung und Verfahren zur Herstellung
DE69226677D1 (de) Verfahren und Gerät zur Zeicheneingabe
DE69321488D1 (de) Verfahren zur extraktion und reinigung von alkaloiden
DE59205564D1 (de) Verfahren zur Abwasseraufbereitung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: BIOVAIL LABORATORIES INTERNATIONAL SRL, ST. MI, BB