DE69231106D1 - Verfahren zur Vorbereitung von Organen auf Langzeitkonservierung und Transplantation - Google Patents

Verfahren zur Vorbereitung von Organen auf Langzeitkonservierung und Transplantation

Info

Publication number
DE69231106D1
DE69231106D1 DE69231106T DE69231106T DE69231106D1 DE 69231106 D1 DE69231106 D1 DE 69231106D1 DE 69231106 T DE69231106 T DE 69231106T DE 69231106 T DE69231106 T DE 69231106T DE 69231106 D1 DE69231106 D1 DE 69231106D1
Authority
DE
Germany
Prior art keywords
organ
cryoprotectant
concentration
buffering agent
osmotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231106T
Other languages
English (en)
Other versions
DE69231106T2 (de
Inventor
Gregory M Fahy
Bijan S Khirabadi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American National Red Cross
Original Assignee
American National Red Cross
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American National Red Cross filed Critical American National Red Cross
Application granted granted Critical
Publication of DE69231106D1 publication Critical patent/DE69231106D1/de
Publication of DE69231106T2 publication Critical patent/DE69231106T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0236—Mechanical aspects
    • A01N1/0242—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components
    • A01N1/0247—Apparatuses, i.e. devices used in the process of preservation of living parts, such as pumps, refrigeration devices or any other devices featuring moving parts and/or temperature controlling components for perfusion, i.e. for circulating fluid through organs, blood vessels or other living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02—Preservation of living parts
    • A01N1/0205—Chemical aspects
    • A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221—Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
DE69231106T 1991-07-08 1992-07-07 Verfahren zur Vorbereitung von Organen auf Langzeitkonservierung und Transplantation Expired - Fee Related DE69231106T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/725,054 US5217860A (en) 1991-07-08 1991-07-08 Method for preserving organs for transplantation by vitrification

Publications (2)

Publication Number Publication Date
DE69231106D1 true DE69231106D1 (de) 2000-06-29
DE69231106T2 DE69231106T2 (de) 2001-02-01

Family

ID=24912973

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231106T Expired - Fee Related DE69231106T2 (de) 1991-07-08 1992-07-07 Verfahren zur Vorbereitung von Organen auf Langzeitkonservierung und Transplantation

Country Status (7)

Country Link
US (2) US5217860A (de)
EP (2) EP0800765B1 (de)
JP (1) JPH07500815A (de)
AT (1) ATE193181T1 (de)
CA (1) CA2113119C (de)
DE (1) DE69231106T2 (de)
WO (1) WO1993000808A1 (de)

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CA2113119A1 (en) 1993-01-21
EP0800765B1 (de) 2000-05-24
EP0594733A1 (de) 1994-05-04
CA2113119C (en) 2003-05-06
US5472876A (en) 1995-12-05
DE69231106T2 (de) 2001-02-01
JPH07500815A (ja) 1995-01-26
ATE193181T1 (de) 2000-06-15
EP0800765A2 (de) 1997-10-15
EP0800765A3 (de) 1998-04-08
WO1993000808A1 (en) 1993-01-21
EP0594733A4 (de) 1994-11-30

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