DE69230670T2 - Zusammensetzungen, die eine blutgerinnselpolymermatrix zur verabreichung von osteogenen proteinen enthalten - Google Patents

Zusammensetzungen, die eine blutgerinnselpolymermatrix zur verabreichung von osteogenen proteinen enthalten

Info

Publication number
DE69230670T2
DE69230670T2 DE69230670T DE69230670T DE69230670T2 DE 69230670 T2 DE69230670 T2 DE 69230670T2 DE 69230670 T DE69230670 T DE 69230670T DE 69230670 T DE69230670 T DE 69230670T DE 69230670 T2 DE69230670 T2 DE 69230670T2
Authority
DE
Germany
Prior art keywords
polymer matrix
administration
compositions containing
osteogenic proteins
cloth polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69230670T
Other languages
English (en)
Other versions
DE69230670D1 (de
Inventor
Eyal Ron
George Schaub
Joseph Turek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetics Institute LLC
Original Assignee
Genetics Institute LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Institute LLC filed Critical Genetics Institute LLC
Application granted granted Critical
Publication of DE69230670D1 publication Critical patent/DE69230670D1/de
Publication of DE69230670T2 publication Critical patent/DE69230670T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/26—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DE69230670T 1991-10-11 1992-10-09 Zusammensetzungen, die eine blutgerinnselpolymermatrix zur verabreichung von osteogenen proteinen enthalten Expired - Fee Related DE69230670T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/776,514 US5171579A (en) 1991-10-11 1991-10-11 Formulations of blood clot-polymer matrix for delivery of osteogenic proteins
PCT/US1992/008628 WO1993006872A1 (en) 1991-10-11 1992-10-09 Formulations of blood clot-polymer matrix for delivery of osteogenic proteins

Publications (2)

Publication Number Publication Date
DE69230670D1 DE69230670D1 (de) 2000-03-16
DE69230670T2 true DE69230670T2 (de) 2000-09-21

Family

ID=25107596

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69230670T Expired - Fee Related DE69230670T2 (de) 1991-10-11 1992-10-09 Zusammensetzungen, die eine blutgerinnselpolymermatrix zur verabreichung von osteogenen proteinen enthalten

Country Status (11)

Country Link
US (1) US5171579A (de)
EP (1) EP0608313B1 (de)
JP (1) JP3336010B2 (de)
KR (1) KR0181984B1 (de)
AT (1) ATE189611T1 (de)
AU (1) AU669133B2 (de)
DE (1) DE69230670T2 (de)
DK (1) DK0608313T3 (de)
ES (1) ES2145013T3 (de)
GR (1) GR3033204T3 (de)
WO (1) WO1993006872A1 (de)

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Also Published As

Publication number Publication date
JP3336010B2 (ja) 2002-10-21
WO1993006872A1 (en) 1993-04-15
AU669133B2 (en) 1996-05-30
DE69230670D1 (de) 2000-03-16
ES2145013T3 (es) 2000-07-01
EP0608313A1 (de) 1994-08-03
GR3033204T3 (en) 2000-08-31
KR0181984B1 (ko) 1999-04-01
EP0608313B1 (de) 2000-02-09
AU2788592A (en) 1993-05-03
JPH07500038A (ja) 1995-01-05
US5171579A (en) 1992-12-15
ATE189611T1 (de) 2000-02-15
DK0608313T3 (da) 2000-05-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: GENETICS INSTITUTE, LLC, CAMBRIDGE, MASS., US

8339 Ceased/non-payment of the annual fee