DE69224294D1 - Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln - Google Patents

Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln

Info

Publication number
DE69224294D1
DE69224294D1 DE69224294T DE69224294T DE69224294D1 DE 69224294 D1 DE69224294 D1 DE 69224294D1 DE 69224294 T DE69224294 T DE 69224294T DE 69224294 T DE69224294 T DE 69224294T DE 69224294 D1 DE69224294 D1 DE 69224294D1
Authority
DE
Germany
Prior art keywords
skin penetration
medicinal products
improved skin
topical release
penetration systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69224294T
Other languages
English (en)
Other versions
DE69224294T2 (de
Inventor
George Deckner
Brian Lombardo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Vicks Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Vicks Inc filed Critical Richardson Vicks Inc
Application granted granted Critical
Publication of DE69224294D1 publication Critical patent/DE69224294D1/de
Publication of DE69224294T2 publication Critical patent/DE69224294T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
DE69224294T 1991-10-16 1992-10-13 Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln Expired - Fee Related DE69224294T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77842491A 1991-10-16 1991-10-16
PCT/US1992/008741 WO1993007902A1 (en) 1991-10-16 1992-10-13 Enhanced skin penetration system for improved topical delivery of drugs

Publications (2)

Publication Number Publication Date
DE69224294D1 true DE69224294D1 (de) 1998-03-05
DE69224294T2 DE69224294T2 (de) 1998-08-20

Family

ID=25113308

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69224294T Expired - Fee Related DE69224294T2 (de) 1991-10-16 1992-10-13 Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln

Country Status (17)

Country Link
US (6) US5780049A (de)
EP (1) EP0608320B1 (de)
JP (1) JPH07500113A (de)
CN (1) CN1072863A (de)
AT (1) ATE162725T1 (de)
AU (1) AU675211B2 (de)
BR (1) BR9206632A (de)
CA (1) CA2120927A1 (de)
CZ (1) CZ85994A3 (de)
DE (1) DE69224294T2 (de)
ES (1) ES2114569T3 (de)
FI (1) FI941771A (de)
HU (1) HUT74560A (de)
MA (1) MA22680A1 (de)
PT (1) PT100963A (de)
SK (1) SK43294A3 (de)
WO (1) WO1993007902A1 (de)

Families Citing this family (123)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG20380A (en) 1991-10-16 1999-02-28 Richardson Vicks Inc Enhanced skin penetration system for improved topical delivery of drugs
WO1993007902A1 (en) * 1991-10-16 1993-04-29 Richardson-Vicks, Inc. Enhanced skin penetration system for improved topical delivery of drugs
JP3555762B2 (ja) * 1991-10-16 2004-08-18 リチャードソン、ビックス、インコーポレーテッド 非イオン性ポリアクリルアミド誘導体を含有した低ｐＨ水性化粧品ゲル
ES2101330T3 (es) * 1992-07-28 1997-07-01 Procter & Gamble Composicion farmaceutica para uso topico que contiene un polimero cationico reticulado y un eter alcoxilado.
US5989536A (en) * 1993-07-03 1999-11-23 The Procter & Gamble Company Personal cleansing compositions containing alkoxylated ether and cationic ammonium salt for deposition of active agent upon the skin
ZA947912B (en) * 1993-10-12 1995-05-24 Broadbent J W Nominees Pty Ltd Treatment of medical disorders associated with free radical formation
AU677519B2 (en) * 1994-03-30 1997-04-24 Alza Corporation Reduction of skin irritation during electrotransport delivery
FR2728793A1 (fr) * 1994-12-28 1996-07-05 Oreal Utilisation d'un antagoniste d'histamine, d'un antagoniste d'interleukine 1 et/ou d'un antagoniste de tnf-alpha dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue
US20020048596A1 (en) * 1994-12-30 2002-04-25 Gregor Cevc Preparation for the transport of an active substance across barriers
CA2154979A1 (en) * 1995-07-28 1997-01-29 Kenneth T. Armstrong Topical phenylephrine preparation
SE9601528D0 (sv) 1996-04-23 1996-04-23 Pharmacia Ab Transdermally administered dextromethorphan as antitissue agent
US5741500A (en) 1996-07-15 1998-04-21 Yates; Alayne Gum growth pad
NL1003992C2 (nl) * 1996-09-10 1998-03-11 Stein Gerrit Cornelis Johan Therapeutische gel met ongeneutraliseerde alfa-hydroxyzuren als werkzame componenten.
WO1999009997A1 (en) * 1997-08-26 1999-03-04 Board Of Regents, The University Of Texas System Edta and other chelators with or without antifungal antimicrobial agents for the prevention and treatment of fungal infections
US6294188B1 (en) 1998-07-09 2001-09-25 Aviana Biopharm Inc. Methods involving changing the constitutive and stimulated secretions of the local reproductive system of women
MXPA00006196A (es) * 1998-10-23 2003-07-21 Idea Ag Metodo para desarrollar, evaluar y utilizar asociaciones de macromoleculas y agregados complejos para obtener mejores tasas de asociacion/desasociacion controlable y carga efectiva.
SI1031347T1 (en) 1999-01-27 2002-10-31 Idea Ag Transnasal transport/immunisation with highly adaptable carriers
ES2173678T3 (es) 1999-01-27 2002-10-16 Idea Ag Vacunacion no invasiva a traves de la piel.
US6444647B1 (en) 1999-04-19 2002-09-03 The Procter & Gamble Company Skin care compositions containing combination of skin care actives
US6319510B1 (en) 1999-04-20 2001-11-20 Alayne Yates Gum pad for delivery of medication to mucosal tissues
FR2795325A1 (fr) * 1999-06-24 2000-12-29 B F B Nouvelle association pharmaceutique a base d'erythromycine et d'un acide dicarboxylique ayant 7 a 13 atomes de carbone
AU5409699A (en) * 1999-07-05 2001-01-22 Idea Ag A method for the improvement of transport across adaptable semi-permeable barriers
US6147102A (en) * 1999-10-26 2000-11-14 Curatek Pharmaceuticals Holding, Inc. Clonidine preparations
AU2005202737B2 (en) * 1999-12-22 2009-01-22 Bayer Innovation Gmbh Use of chemotherapeutic agents
US7557235B2 (en) 2000-02-16 2009-07-07 Lubrizol Advanced Materials, Inc. Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom
WO2001080827A2 (en) * 2000-04-21 2001-11-01 Nature's Cure Salicylic acid acne spray formulations and methods for treating acne with same
GB0010757D0 (en) 2000-05-05 2000-06-28 Astrazeneca Ab Chemical compounds
FR2810883B1 (fr) 2000-06-28 2006-07-28 Seppic Sa Nouveaux latex inverses autoinversibles sur des esters d'acides gras, compositions cosmetiques, dermocosmetiques, dermopharmaceutiques ou pharmaceutiques en comportant
US6576702B2 (en) 2000-07-20 2003-06-10 Noveon Ip Holdings Corp. Plasticized waterborne polyurethane dispersions and manufacturing process
US20020193321A1 (en) * 2000-12-12 2002-12-19 Mohan Vishnupad Dual dispenser for aesthitically acceptable delivery of anhydrous skin treatment compositions
US6638981B2 (en) * 2001-08-17 2003-10-28 Epicept Corporation Topical compositions and methods for treating pain
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
GB0121941D0 (en) 2001-09-11 2001-10-31 Astrazeneca Ab Chemical compounds
US6986895B2 (en) 2001-09-12 2006-01-17 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Thickened cosmetic compositions
US20030118620A1 (en) * 2001-09-12 2003-06-26 Unilever Home & Personal Care Usa, Division Of Conopco Inc. Thickener system for cosmetic compositions
US20030064084A1 (en) * 2001-09-24 2003-04-03 Bradley Pharmaceuticals, Inc. Novel benzoyl peroxide compositions for the treatment of dermatological disorders and methods for their use
US7022342B2 (en) 2002-03-28 2006-04-04 Andrx Corporation, Inc. Controlled release oral dosage form of beta-adrenergic blocking agents
US7358295B2 (en) * 2002-04-05 2008-04-15 Lubrizol Advanced Materials, Inc. Hybrid polymer composition, and article therefrom
US6897281B2 (en) * 2002-04-05 2005-05-24 Noveon Ip Holdings Corp. Breathable polyurethanes, blends, and articles
US20030198616A1 (en) * 2002-04-23 2003-10-23 Combe Incorporated Moisturizing skin gel and method
CN100341589C (zh) 2002-05-24 2007-10-10 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
US20050209428A1 (en) * 2002-06-19 2005-09-22 Krishnan Tamareselvy Breathable polyurethanes, blends, and articles
US7099713B2 (en) 2002-06-28 2006-08-29 Battelle Memorial Institute Skin conduction and transport systems
AU2003251875A1 (en) * 2002-07-15 2004-02-02 Combinatorx, Incorporated Combination therapy for the treatment of neoplasms
US20040171561A1 (en) * 2002-09-03 2004-09-02 Popp Karl F. Topical formulations for treatment of rosacea
US20040043946A1 (en) * 2002-09-03 2004-03-04 Popp Karl F. Topical formulations for treatment of skin disorders
US20040167223A1 (en) * 2002-09-03 2004-08-26 Popp Karl F. Topical antibacterial formulations
US20040241130A1 (en) * 2002-09-13 2004-12-02 Krishnan Tamareselvy Multi-purpose polymers, methods and compositions
US7378479B2 (en) * 2002-09-13 2008-05-27 Lubrizol Advanced Materials, Inc. Multi-purpose polymers, methods and compositions
GB0222522D0 (en) 2002-09-27 2002-11-06 Controlled Therapeutics Sct Water-swellable polymers
US7473432B2 (en) * 2002-10-11 2009-01-06 Idea Ag NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
WO2004069221A1 (en) * 2003-02-03 2004-08-19 Warner-Lambert Company Llc Improved formulation for skin-lightening agents
HUE045608T2 (hu) * 2003-06-06 2020-01-28 Univ Texas Antimikrobiális öblítõoldatok
FR2856691B1 (fr) 2003-06-26 2005-08-26 Seppic Sa Nouveau polymere en poudre, procede pour sa preparation et utilisation comme epaississant
US20050025817A1 (en) * 2003-07-03 2005-02-03 Bhatia Kuljit S. Delivery system for topical medications
US7776355B2 (en) * 2003-07-03 2010-08-17 Medics Pharmaceutical Corporation Delivery system for topical medications
US20060229258A1 (en) * 2003-07-30 2006-10-12 Daniela Serikaku Steroidal compositions containing hydroxycarboxylic acids and methods of using the same
FR2861397B1 (fr) 2003-10-22 2006-01-20 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Nouveau latex inverse concentre, procede pour sa preparation et utilisation dans l'industrie
US20050226920A1 (en) * 2004-04-13 2005-10-13 Kirk Voelker Method of decreasing nicotine withdrawal symptoms during smoking cessation.
US7479289B2 (en) * 2004-07-02 2009-01-20 Medicis Pharmaceutical Corporation Stable cleanser compositions containing sulfur
US7655682B2 (en) * 2004-07-02 2010-02-02 Medicis Pharmaceutical Corporation Triple anti-irritant composition
GB0417401D0 (en) 2004-08-05 2004-09-08 Controlled Therapeutics Sct Stabilised prostaglandin composition
US8137754B2 (en) * 2004-08-06 2012-03-20 Lubrizol Advanced Materials, Inc. Hydroxyl-terminated thiocarbonate containing compounds, polymers, and copolymers, and polyurethanes and urethane acrylics made therefrom
WO2006020281A1 (en) 2004-08-06 2006-02-23 Noveon, Inc. Polyurethanes and urethane acrylics made from hydroxyl-terminated thiocarbonate containing compounds
JP2008519784A (ja) * 2004-11-12 2008-06-12 イデア アクチェンゲゼルシャフト 皮膚状態の治療における拡張表面凝集体
FR2879607B1 (fr) 2004-12-16 2007-03-30 Seppic Sa Nouveaux latex inverse concentre, procede pour sa preparation, et utilisation dans l'industrie
CA2596035A1 (en) * 2005-01-28 2006-08-03 Collegium Pharmaceutical, Inc. Non-ionic non-aqueous vehicles for topical and oral administration of carrier-complexed active agents
AR054336A1 (es) * 2005-03-30 2007-06-20 Astion Dev As Tratamiento de enfermedades dermatologicas y del prurito
US20060223786A1 (en) * 2005-04-01 2006-10-05 Smith David J Transdermal pain control method and device
FR2886851B1 (fr) * 2005-06-10 2007-10-05 Galderma Sa Composition a base d'une avermectine et de metronidazole notamment pour le traitement de la rosacee
US7541347B2 (en) * 2007-04-02 2009-06-02 Medicis Pharmaceutical Coropration Minocycline oral dosage forms for the treatment of acne
US8722650B1 (en) 2005-06-24 2014-05-13 Medicis Pharmaceutical Corporation Extended-release minocycline dosage forms
US7544373B2 (en) * 2007-04-02 2009-06-09 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080242642A1 (en) 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US8252776B2 (en) 2007-04-02 2012-08-28 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US20080241235A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline oral dosage forms for the treatment of acne
US7919483B2 (en) * 2005-06-24 2011-04-05 Medicis Pharmaceutical Corporation Method for the treatment of acne
WO2007117352A2 (en) * 2006-02-08 2007-10-18 Howard Murad Topical therapeutic delivery system
WO2007103555A2 (en) * 2006-03-08 2007-09-13 Nuviance, Inc. Transdermal drug delivery compositions and topical compositions for application on the skin
EP2010133B1 (de) 2006-03-31 2016-05-04 Stiefel Research Australia Pty Ltd Formbares suspensionsgel
US20070248657A1 (en) * 2006-04-25 2007-10-25 Smith David J Multi-compartment transdermal pain control device
GB0613333D0 (en) 2006-07-05 2006-08-16 Controlled Therapeutics Sct Hydrophilic polyurethane compositions
GB0613638D0 (en) 2006-07-08 2006-08-16 Controlled Therapeutics Sct Polyurethane elastomers
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
US8323672B2 (en) 2006-08-29 2012-12-04 Karykion Corporation Method of removing ticks from the skin and reducing the risk of bites
US7604814B2 (en) * 2006-08-29 2009-10-20 Karykion Inc. Method of removing ticks from the epidermal tissue of humans and other mammals
JP5378219B2 (ja) 2006-10-02 2013-12-25 テックフィールズ バイオケム カンパニー リミテッド 非常に高い皮膚浸透率を有するプロスタグランジン及び関連化合物の正荷電水溶性プロドラッグ
GB0620685D0 (en) 2006-10-18 2006-11-29 Controlled Therapeutics Sct Bioresorbable polymers
AU2006350707A1 (en) 2006-11-08 2008-05-15 Chongxi Yu Transdermal delivery systems of peptides and related compounds
PL2121593T3 (pl) 2006-12-10 2015-11-30 Chongxi Yu Przezskórne systemy dostarczania antybiotyków beta-laktamowych
HUE031712T2 (en) 2007-01-15 2017-08-28 Chongxi Yu Retinoids and retinoid-like compounds with positively charged water-soluble prodrugs having very high skin penetration rates
ES2607901T3 (es) 2007-01-31 2017-04-04 Chongxi Yu Profármacos hidrosolubles cargados positivamente de 1H-imidazo[4,5-c]quinolin-4-aminas y compuestos relacionados con ratas de penetración de piel muy altas
US20080188445A1 (en) * 2007-02-02 2008-08-07 Warner Chilcott Company Inc. Tetracycline compositions for topical administration
WO2008097851A1 (en) * 2007-02-02 2008-08-14 Warner Chilcott Company, Inc. Tetracycline compositions for topical administration
US20080241197A1 (en) * 2007-04-02 2008-10-02 Medicis Pharmaceutical Corporation Minocycline dosage forms for the treatment of acne
BRPI0721709B1 (pt) 2007-06-04 2024-03-12 Techfields Inc. PRÓ-FÁRMACOS DE NSAIAs, PROCESSO PARA PREPARAÇÃO DOS MESMOS, SEU USO, SISTEMAS TERAPÊUTICOS DE APLICAÇÃO TRANSDÉRMICA E COMPOSIÇÃO QUE OS COMPREENDE
WO2010017310A1 (en) 2008-08-06 2010-02-11 Medicis Pharmaceutical Corporation Method for the treatment of acne and certain dosage forms thereof
WO2010047831A1 (en) * 2008-10-23 2010-04-29 Nycomed Us Inc. Stable metronidazole gel formulations
US20100221313A1 (en) * 2008-12-01 2010-09-02 Innovative Pharmaceuticals, Llc Transdermal reservoir patch
RU2630577C2 (ru) 2008-12-04 2017-09-11 Чунси ЮЙ Композиции интенсивного проникновения и их применение
AU2010224076B2 (en) 2009-03-11 2014-10-02 Isp Investments Inc. Thickening additive compositions
FR2943677B1 (fr) * 2009-03-31 2012-10-26 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Nouveau polymere epaississant sous forme de poudre
US8920392B2 (en) 2009-05-05 2014-12-30 Watson Laboratories, Inc. Method for treating overactive bladders and a device for storage and administration of topical oxybutynin compositions
JP6352587B2 (ja) 2009-05-08 2018-07-11 テックフィールズ バイオケム カンパニー リミテッド ペプチド及びペプチド関連化合物の高浸透性プロドラッグ組成物
US9969751B2 (en) 2009-06-10 2018-05-15 Techfields Pharma Co., Ltd. High penetration prodrug compositions of antimicrobials and antimicrobial-related compounds
CN102008730B (zh) * 2009-09-08 2012-07-04 中国科学院理化技术研究所 透皮药物组合制剂和透皮药物试剂盒
US9561241B1 (en) 2011-06-28 2017-02-07 Medicis Pharmaceutical Corporation Gastroretentive dosage forms for minocycline
US20150080352A1 (en) 2012-03-09 2015-03-19 Bayer Materialscience Llc Aqueous polyurethane dispersion in the treatment of acne
MX2014013910A (es) 2012-05-16 2015-06-04 Techfields Pharma Co Ltd Composiciones de profarmacos de alta penetracion y composiciones farmaceuticas de los mismos para el tratamiento de afecciones pulmonares.
FR2992323B1 (fr) 2012-06-25 2015-07-03 Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic Nouveau latex inverse auto-inversible exempt de tensioactif, son utilisation comme agent epaississant dans une composition cosmetique
US8936814B2 (en) * 2012-11-30 2015-01-20 Zuri A. Murrell Skin cream
TWI522102B (zh) 2013-04-30 2016-02-21 長庚醫療財團法人 組合物於製備治療或預防性治療痤瘡的藥物之用途
FR3011464B1 (fr) 2013-10-07 2015-11-20 Snf Sas Utilisation en cosmetique de polymeres obtenus par polymerisation en emulsion inverse basse concentration avec un faible taux de monomeres neutralises
FR3024736B1 (fr) 2014-08-06 2016-08-26 Snf Sas Utilisation dans des compositions detergentes de polymeres obtenus par polymerisation en emulsion inverse basse concentration avec un faible taux de monomeres neutralises
US9687455B2 (en) 2014-08-14 2017-06-27 John Daniel Dobak Sodium tetradecyl sulfate formulations for treatment of adipose tissue
CA2972065A1 (en) 2014-12-23 2016-06-30 Intellectual Property Associates, Llc Methods and formulations for transdermal administration
US9351945B1 (en) 2015-02-27 2016-05-31 John Daniel Dobak, III Reduction of adipose tissue
US10149843B1 (en) 2017-02-07 2018-12-11 Gneus Lifescineces Inc. Pharmaceutical compositions and methods of using the same
US10413505B1 (en) 2017-02-07 2019-09-17 Genus Lifesciences Inc. Pharmaceutical compositions and methods of using the same
US10231961B1 (en) 2017-02-07 2019-03-19 Genus Lifesciences Inc. Pharmaceutical compositions and methods of using the same
US10758329B1 (en) 2019-08-20 2020-09-01 Raymond L. Wright, III Hydrating mouth guard
CN113143845A (zh) * 2020-10-13 2021-07-23 西北师范大学 一种丙烯酰胺-盐酸普奈洛尔水凝胶及其制备方法

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US128474A (en) * 1872-07-02 Improvement in stove-pipe thimbles
US3624019A (en) * 1970-12-15 1971-11-30 Nalco Chemical Co Process for rapidly dissolving water-soluble polymers
USRE28474F1 (en) * 1970-12-15 1983-12-20 Nalco Chemical Co Process for rapidly dissolving water-soluble polymers
US3920808A (en) * 1973-05-08 1975-11-18 Univ Minnesota Method of protecting human skin from actinic radiation
US3920810A (en) * 1974-04-23 1975-11-18 Burton Parsons And Company Inc Polyacrylamide containing ophthalmic solutions
US4039501A (en) * 1975-05-30 1977-08-02 National Patent Development Corporation Plasticized hydrophilic polymers
US4675009A (en) * 1977-11-07 1987-06-23 Lec Tec Corporation Drug dispensing device for transdermal delivery of medicaments
US4307717A (en) * 1977-11-07 1981-12-29 Lectec Corporation Sterile improved bandage containing a medicament
US4355028A (en) * 1978-04-04 1982-10-19 Westwood Pharmaceuticals, Inc. Composition for treating acne vulgaris
US4318907A (en) * 1978-04-04 1982-03-09 Westwood Pharmaceuticals, Inc. Method for treating acne vulgaris and compositions useful for that purpose
US4954487A (en) * 1979-01-08 1990-09-04 The Procter & Gamble Company Penetrating topical pharmaceutical compositions
JPS596287B2 (ja) * 1980-11-28 1984-02-10 日東電工株式会社 医薬製剤
US4938951A (en) * 1980-12-30 1990-07-03 Union Carbide Chemicals And Plastics Company Inc. Potentiation of topical compositions wherein a uniform microdispersion of active agent is formed
AU8409582A (en) * 1981-06-15 1982-12-23 Alcon Laboratories, Inc. Urea and carboxyvinyl polymers gel compositions
US4478853A (en) * 1982-05-17 1984-10-23 S. C. Johnson & Son, Inc. Skin conditioning composition
US4540568A (en) * 1982-10-14 1985-09-10 Trager Seymour F Injectionable viscoelastic ophthalmic gel
US4948576A (en) * 1983-02-18 1990-08-14 Johnson & Johnson Consumer Products, Inc. Detergent compositions
US4650827A (en) * 1983-11-02 1987-03-17 Allied Corporation Stable water-in-oil emulsions
GB8401206D0 (en) * 1984-01-17 1984-02-22 Allied Colloids Ltd Polymers and aqueous solutions
GB8414950D0 (en) * 1984-06-12 1984-07-18 Allied Colloids Ltd Cationic polyelectrolytes
GB8416453D0 (en) * 1984-06-28 1984-08-01 Allied Colloids Ltd Aqueous polymer dispersions
US5017367A (en) * 1984-10-01 1991-05-21 Stojkoski Radmila G Skin treatment preparation
US4692462A (en) * 1985-03-18 1987-09-08 Menley & James Laboratories, Ltd. Compositions and method of controlling transdermal penetration of topical and systemic agents
US4806345C1 (en) * 1985-11-21 2001-02-06 Johnson & Son Inc C Cross-linked cationic polymers for use in personal care products
GB8531118D0 (en) * 1985-12-18 1986-01-29 Allied Colloids Ltd Copolymers
US5200448A (en) * 1986-01-03 1993-04-06 Exxon Chemical Patents Inc. Freeze-thaw stable polyacrylamide emulsions
US5057566A (en) * 1986-02-19 1991-10-15 Nippon Zeon Co., Ltd. Thermoplastic rubber compositions
US4731242A (en) * 1986-03-21 1988-03-15 Victor Palinczar Waterproof sunscreen compositions
US4704436A (en) * 1986-05-02 1987-11-03 Barabas Eugene S Water soluble complex of a poly(vinylpyrrolidone) copolymer and α-methyl-(2-methylpropyl)benzene acetic acid
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4837019A (en) * 1986-08-11 1989-06-06 Charles Of The Ritz Group Ltd. Skin treatment composition and method for treating burned skin
US5183664A (en) * 1986-09-20 1993-02-02 Smith And Nephew Associated Companies P.L.C. Thin film adhesive dressings preparation and use
GB8622797D0 (en) * 1986-09-22 1986-10-29 Allied Colloids Ltd Polymeric particles
CA1329283C (en) * 1986-10-01 1994-05-03 David Farrar Water soluble polymeric compositions
US5422118A (en) * 1986-11-07 1995-06-06 Pure Pac, Inc. Transdermal administration of amines with minimal irritation and high transdermal flux rate
US4929577A (en) * 1987-03-11 1990-05-29 Medi-Tech International Corporation Transparent wound dressings in sheet form
US4885161A (en) * 1987-03-11 1989-12-05 Medi-Tech International Corporation Wound dressings in gelled paste form
US5059189A (en) * 1987-09-08 1991-10-22 E. R. Squibb & Sons, Inc. Method of preparing adhesive dressings containing a pharmaceutically active ingredient
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US5147923A (en) * 1987-10-05 1992-09-15 Ciba-Geigy Corporation Thermotropic biphilic hydrogels and hydroplastics
US5104954A (en) * 1987-10-05 1992-04-14 Ciba-Geigy Corporation Thermostropic biphilic hydrogels and hydroplastics
US5057560A (en) * 1987-10-05 1991-10-15 Ciba-Geigy Corporation Thermotropic copolymer hydrogels from N,N-dimethylacrylamide and methoxy-ethyl (meth) acrylate
US4948586A (en) * 1987-11-02 1990-08-14 Lim Technology Laboratories, Inc. Microencapsulated insecticidal pathogens
JPH07116035B2 (ja) * 1987-12-08 1995-12-13 塩野義製薬株式会社 被膜形成性抗真菌剤組成物
JPH0749050B2 (ja) * 1988-01-18 1995-05-31 久光製薬株式会社 含水ゲル組成物
US5039516A (en) * 1988-08-24 1991-08-13 Dento-Med Industries, Inc. Sunscreen preparation
US4883659A (en) * 1988-08-24 1989-11-28 Dento-Med Industries, Inc. Skin treatment preparation
US4927408A (en) * 1988-10-03 1990-05-22 Alza Corporation Electrotransport transdermal system
GB8909095D0 (en) * 1989-04-21 1989-06-07 Allied Colloids Ltd Thickened aqueous compositions
US5009969A (en) * 1989-05-26 1991-04-23 Hi-Tek Polymers, Inc. Dual action sunscreen composition
US5208031A (en) * 1989-06-06 1993-05-04 Kelly Patrick D Sexual lubricants containing zinc as an anti-viral agent
US5100658A (en) * 1989-08-07 1992-03-31 The Procter & Gamble Company Vehicle systems for use in cosmetic compositions
FR2651126B1 (fr) * 1989-08-29 1991-12-06 Oreal Association de dihydroxyacetone et de derives indoliques pour conferer a la peau une coloration similaire au bronzage naturel et procede de mise en óoeuvre.
GB2236760A (en) * 1989-10-11 1991-04-17 Inverness Corp Shaving gel
FR2653334B1 (fr) * 1989-10-19 1991-12-20 Erphar Ste Civile Preparation cosmetique de bronzage.
FR2657607B1 (fr) * 1990-01-30 1992-04-30 Durand Muriel Procede de protection de la dihydroxyacetone, dihydroxyacetone protegee par ce procede et produit cosmetique contenant une telle dihydroxyacetone protegee.
US5091443A (en) * 1990-02-07 1992-02-25 Becton, Dickinson And Company Composition for gelling liquids
US5043359A (en) * 1990-03-05 1991-08-27 Dow Corning Corporation Skin conditioning compositions containing glyceroxyfunctional silanes and siloxanes
US5110853A (en) * 1990-08-27 1992-05-05 Exxon Chemical Patents Inc. Freeze-thaw stable polyacrylamide emulsions
US5169624A (en) * 1991-02-23 1992-12-08 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Waterproof sunblock compositions
AU1775592A (en) * 1991-04-03 1992-11-02 Richardson-Vicks Inc. Stabilized emulsion compositions for imparting an artificial tan to human skin
US5221530A (en) * 1991-06-24 1993-06-22 Helene Curtis, Inc. Mild conditioning shampoo with a high foam level containing an anionic surfactant-cationic acrylate/acrylamide copolymer conditioning agent
WO1993007902A1 (en) * 1991-10-16 1993-04-29 Richardson-Vicks, Inc. Enhanced skin penetration system for improved topical delivery of drugs
EG20380A (en) * 1991-10-16 1999-02-28 Richardson Vicks Inc Enhanced skin penetration system for improved topical delivery of drugs
JP3555762B2 (ja) * 1991-10-16 2004-08-18 リチャードソン、ビックス、インコーポレーテッド 非イオン性ポリアクリルアミド誘導体を含有した低ｐＨ水性化粧品ゲル
US5302378A (en) * 1992-06-17 1994-04-12 Chesebrough-Pond's Usa Co. Self-tanner cosmetic compositions
US5232688A (en) * 1992-06-17 1993-08-03 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Self-tanner cosmetic compositions
ES2101330T3 (es) * 1992-07-28 1997-07-01 Procter & Gamble Composicion farmaceutica para uso topico que contiene un polimero cationico reticulado y un eter alcoxilado.
US5618522A (en) * 1995-01-20 1997-04-08 The Procter & Gamble Company Emulsion compositions

Also Published As

Publication number Publication date
CN1072863A (zh) 1993-06-09
EP0608320A1 (de) 1994-08-03
FI941771A0 (fi) 1994-04-15
DE69224294T2 (de) 1998-08-20
ATE162725T1 (de) 1998-02-15
BR9206632A (pt) 1995-04-25
US5776485A (en) 1998-07-07
ES2114569T3 (es) 1998-06-01
US5780049A (en) 1998-07-14
US5874095A (en) 1999-02-23
PT100963A (pt) 1993-10-29
US5773023A (en) 1998-06-30
SK43294A3 (en) 1995-01-12
US5756119A (en) 1998-05-26
JPH07500113A (ja) 1995-01-05
HUT74560A (en) 1997-01-28
FI941771A (fi) 1994-04-15
WO1993007902A1 (en) 1993-04-29
MA22680A1 (fr) 1993-07-01
CA2120927A1 (en) 1993-04-29
AU675211B2 (en) 1997-01-30
US5756118A (en) 1998-05-26
HU9401107D0 (en) 1994-08-29
CZ85994A3 (en) 1994-12-15
AU2806492A (en) 1993-05-21
EP0608320B1 (de) 1998-01-28

Similar Documents

Publication Publication Date Title
DE69224294D1 (de) Verbesserte hautpenetrationssysteme fuer erhoehte topische freisetzung von arzneimitteln
ES2118834T3 (es) Sistema mejorado de penetracion en la piel para la administracion topica mejorada de farmacos.
MX9304530A (es) Suministro topico mejorado de farmacos.
ES2136723T3 (es) Utilizacion de n-aril-metilen-etilen-diamino-triacetatos, n-aril-metilen-imino-diacetatos o n,n'-diaril-metilen-etilen-diamino-acetatos contra el estres oxidante.
IL112572A0 (en) Dexanabinol derivatives and their use as nmda blocking pharmaceutical compositions
FI953442A (fi) Gonadotropiinia sisältäviä pakastekuivattuja pallosia
NO954544D0 (no) Stabile flytende preparater av gamma-interferon
FR2598320B1 (fr) Compositions pharmaceutiques hydrosolubles contenant de l'ubiquinone en tant que principe actif, utiles dans differentes applications therapeutiques
HK1001323A1 (en) Anti-irritant and desensitizing compositions and methods of their use
LT96093A (en) The active ingredient of pharmaceutical composition for treating aphtae and stomatitis
PT986390E (pt) Composicoes farmaceuticas que contem cicloridrato de cinchonina
TH13510A (th) ระบบนำส่งยาเฉพาะที่ที่ดีขึ้นซึ่งแทรกซึมผ่านผิวหนังได้เพิ่มขึ้น
TH13510EX (th) ระบบนำส่งยาเฉพาะที่ที่ดีขึ้นซึ่งแทรกซึมผ่านผิวหนังได้เพิ่มขึ้น
SE9203296D0 (sv) The use of inositoltrisphate for the preparing of medicaments
UA19287A (uk) Діетиламіhоетиламіда 1-пропіл-2-оксо-4-гідроксіхіhолін-3-карбонової кислоти гідрохлорид, що проявляє анестезуючу, протиаритмічhу, аhтиоксидаhтhу, аhтимікробну та фуhгіцидhу активhість
GEP19991586B (en) Pharmaceutical Formulation
KR970005306A (ko) 항-HIV 제제로서의 IFN-ω
UA12937A (uk) Засіб для локальhого лікуваhhя гhійhо-запальhих раh та опіків, іhфіковаhих стафілококом
RU94019942A (ru) Фармацевтическая композиция для повышения проницаемости кожи для улучшенной локальной доставки лекарств

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee