DE69219331T3 - Verbesserungen im bezug auf kontrastmittel - Google Patents

Verbesserungen im bezug auf kontrastmittel

Info

Publication number
DE69219331T3
DE69219331T3 DE69219331T DE69219331T DE69219331T3 DE 69219331 T3 DE69219331 T3 DE 69219331T3 DE 69219331 T DE69219331 T DE 69219331T DE 69219331 T DE69219331 T DE 69219331T DE 69219331 T3 DE69219331 T3 DE 69219331T3
Authority
DE
Germany
Prior art keywords
pct
contrast agents
date dec
sec
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69219331T
Other languages
English (en)
Other versions
DE69219331D1 (de
DE69219331T2 (de
Inventor
Jo Klaveness
Pal Rongved
Per Strande
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GE Healthcare AS
Original Assignee
Nycomed Imaging AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27265687&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69219331(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB919111890A external-priority patent/GB9111890D0/en
Priority claimed from GB919114570A external-priority patent/GB9114570D0/en
Priority claimed from GB929200409A external-priority patent/GB9200409D0/en
Application filed by Nycomed Imaging AS filed Critical Nycomed Imaging AS
Publication of DE69219331D1 publication Critical patent/DE69219331D1/de
Application granted granted Critical
Publication of DE69219331T2 publication Critical patent/DE69219331T2/de
Publication of DE69219331T3 publication Critical patent/DE69219331T3/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
DE69219331T 1991-06-03 1992-06-03 Verbesserungen im bezug auf kontrastmittel Expired - Fee Related DE69219331T3 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB919111890A GB9111890D0 (en) 1991-06-03 1991-06-03 Improvements in or relating to contrast agents
GB919114570A GB9114570D0 (en) 1991-07-05 1991-07-05 Improvements in or relating to contrast agents
GB929200409A GB9200409D0 (en) 1992-01-09 1992-01-09 Improvements in or relating to contrast agents
PCT/EP1992/001327 WO1992021382A1 (en) 1991-06-03 1992-06-03 Improvements in or relating to contrast agents

Publications (3)

Publication Number Publication Date
DE69219331D1 DE69219331D1 (de) 1997-05-28
DE69219331T2 DE69219331T2 (de) 1997-09-04
DE69219331T3 true DE69219331T3 (de) 2001-06-07

Family

ID=27265687

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69219331T Expired - Fee Related DE69219331T3 (de) 1991-06-03 1992-06-03 Verbesserungen im bezug auf kontrastmittel

Country Status (13)

Country Link
US (2) US5558857A (de)
EP (1) EP0586524B2 (de)
JP (1) JP3319754B2 (de)
AT (1) ATE151992T1 (de)
CA (1) CA2110590A1 (de)
DE (1) DE69219331T3 (de)
DK (1) DK0586524T3 (de)
ES (1) ES2103947T5 (de)
FI (1) FI935394A (de)
HK (1) HK1006946A1 (de)
IE (1) IE921797A1 (de)
NO (1) NO934366L (de)
WO (1) WO1992021382A1 (de)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5656211A (en) 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5469854A (en) 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US6001335A (en) 1989-12-22 1999-12-14 Imarx Pharmaceutical Corp. Contrasting agents for ultrasonic imaging and methods for preparing the same
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US6551576B1 (en) 1989-12-22 2003-04-22 Bristol-Myers Squibb Medical Imaging, Inc. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5776429A (en) 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US6146657A (en) 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
IN172208B (de) * 1990-04-02 1993-05-01 Sint Sa
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5874062A (en) 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
US5205290A (en) * 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
JP3231768B2 (ja) * 1991-09-17 2001-11-26 ソーナス ファーマシューティカルス,インコーポレイテッド 気体状超音波造影剤及び超音波造影剤として使用する気体の選定方法
US6875420B1 (en) 1991-09-17 2005-04-05 Amersham Health As Method of ultrasound imaging
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them
ES2135466T3 (es) * 1992-03-06 1999-11-01 Nycomed Imaging As Mejoras introducidas en agentes de contraste.
US5674468A (en) * 1992-03-06 1997-10-07 Nycomed Imaging As Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Colloids with phase difference as contrast ultrasound agents
US5558855A (en) * 1993-01-25 1996-09-24 Sonus Pharmaceuticals Phase shift colloids as ultrasound contrast agents
CA2154590C (en) * 1993-01-25 2001-06-12 Steven C. Quay Phase shift colloids as ultrasound contrast agents
US5798091A (en) 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
DE69434119T3 (de) * 1993-07-30 2011-05-05 Imcor Pharmaceutical Co., San Diego Stabilisierte mikrogasbläschen-zusammensetzungen für echographie
PT682530E (pt) 1993-12-15 2003-06-30 Bracco Research Sa Misturas de gases uteis como meios de contraste para ultrassons
DE4406474A1 (de) 1994-02-23 1995-08-24 Schering Ag Gas enthaltende Mikropartikel, diese enthaltende Mittel, deren Verwendung in der Ultraschalldiagnostik, sowie Verfahren zur Herstellung der Partikel und Mittel
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
US6743779B1 (en) 1994-11-29 2004-06-01 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
US5997898A (en) 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US5558092A (en) * 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US6033645A (en) 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
US6231834B1 (en) 1995-06-07 2001-05-15 Imarx Pharmaceutical Corp. Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
DE19602930A1 (de) * 1996-01-18 1997-07-24 Schering Ag Poröse Matrices aus niedermolekularen Substanzen zur Genierung stabiler Gasblasensuspensionen, deren Verwendung als Ultraschallkontrastmittel sowie Verfahren zu deren Herstellung
HU226714B1 (en) * 1996-03-05 2009-07-28 Acusphere Microencapsulated fluorinated gases for use as imaging agents
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
EP0935415B1 (de) 1996-05-01 2006-11-22 Imarx Pharmaceutical Corp. In vitro verfahren zum einbringen von nukleinsäuren in eine zelle
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
ATE366588T1 (de) 1996-09-11 2007-08-15 Imarx Pharmaceutical Corp Verfahren zur diagnostischen bilderzeugung der nierenregion unter verwendung eines kontrastmittels und eines vasodilators
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6143276A (en) 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
US6045777A (en) * 1997-06-30 2000-04-04 Acusphere, Inc. Method for enhancing the echogenicity and decreasing the attenuation of microencapsulated gases
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US6123923A (en) 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
US6048736A (en) * 1998-04-29 2000-04-11 Kosak; Kenneth M. Cyclodextrin polymers for carrying and releasing drugs
FR2780901B1 (fr) * 1998-07-09 2000-09-29 Coletica Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant
US6426145B1 (en) 1999-05-20 2002-07-30 Scimed Life Systems, Inc. Radiopaque compositions for visualization of medical devices
US6572840B1 (en) 1999-07-28 2003-06-03 Bristol-Myers Squibb Pharma Company Stable microbubbles comprised of a perfluoropropane encapsulated lipid moiety for use as an ultrasound contrast agent
EP2286843A3 (de) 2000-06-02 2011-08-03 Bracco Suisse SA Arzneimitteln zur Zielgerichtung von Endothelzellen
DE60223239T2 (de) * 2001-04-06 2008-08-14 Bracco Research S.A. Vorrichtung zur Messung lokaler physikalischer Parameter in einem flüssigkeitsgefüllten Hohlraum
AU2003278807A1 (en) 2002-03-01 2004-08-13 Bracco International B.V. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
EP2301587B1 (de) 2002-03-01 2014-06-25 Dyax Corp. KDR- und VEGF/KDR-bindende Peptide sowie ihre Verwendung bei der Diagnose und Therapie
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
AU2003240000A1 (en) 2002-06-12 2003-12-31 Boston Scientific Limited Bulking agents
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
SI2949658T1 (sl) 2003-03-03 2018-10-30 Dyax Corp. Peptidi, ki specifično vežejo HGF receptor (cMet) in njihove uporabe
US7976823B2 (en) 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
AU2004285595A1 (en) 2003-10-31 2005-05-12 Point Biomedical Corporation Reconstitutable microsphere compositions useful as ultrasonic contrast agents
US7736671B2 (en) 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US7311861B2 (en) 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
US8425550B2 (en) 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7727555B2 (en) 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7858183B2 (en) 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US8123693B2 (en) * 2005-06-20 2012-02-28 Conceptus, Inc. Methods and devices for determining lumen occlusion
US9463426B2 (en) 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US8007509B2 (en) 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US8152839B2 (en) 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US7947368B2 (en) 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
US8585616B2 (en) * 2009-10-09 2013-11-19 Conceptus, Inc. Methods and apparatus for determining fallopian tube occlusion
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
JP6420817B2 (ja) 2013-03-15 2018-11-07 バイオコンパティブルズ ユーケー リミテッド 結像可能な塞栓性微小球
GB2521997A (en) 2013-09-06 2015-07-15 Biocompatibles Uk Ltd Radiopaque polymers
GB2519738A (en) 2013-09-06 2015-05-06 Biocompatibles Uk Ltd Radiopaque polymers
CN112716895A (zh) * 2020-12-18 2021-04-30 济南大学 基于苯丁酸修饰的普朗尼克f127的穿心莲内酯载药胶束及其制备
CN114808179B (zh) * 2022-03-30 2023-06-16 华南理工大学 一种可控弛豫时间的复合材料及其制备方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3173476D1 (en) * 1980-11-17 1986-02-20 Schering Ag Composition generating microbubbles
SE8204244L (sv) * 1982-07-09 1984-01-10 Ulf Schroder Kristalliserad kolhydratsmatris for biologiskt aktiva substanser
DE3313946A1 (de) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
DE3313947A1 (de) 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen Mikropartikel und gasblaeschen enthaltende ultraschall-kontrastmittel
JPS60231609A (ja) * 1984-04-28 1985-11-18 Terumo Corp リポソ−ム製剤
EP0184899B1 (de) * 1984-11-01 1990-04-18 Nycomed As Paramagnetische Kontrastmittel für die Anwendung in "in vivo" NMR-diagnostischen Methoden und die Herstellung davon
JP2907911B2 (ja) * 1988-02-05 1999-06-21 シエーリング アクチエンゲゼルシヤフト 超音波造影剤、その製造方法及び該超音波造影剤からなる診断又は治療用製剤
AU636481B2 (en) * 1990-05-18 1993-04-29 Bracco International B.V. Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography
PH31064A (en) * 1990-09-07 1998-02-05 Nycomed As Of Nycoveten Polymers containing diester units.
AU635449B2 (en) * 1990-10-05 1993-03-18 Bracco International B.V. Method for the preparation of stable suspensions of hollow gas-filled microspheres suitable for ultrasonic echography
US5370901A (en) * 1991-02-15 1994-12-06 Bracco International B.V. Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients

Also Published As

Publication number Publication date
NO934366D0 (no) 1993-12-01
HK1006946A1 (en) 1999-03-26
JPH06509065A (ja) 1994-10-13
ATE151992T1 (de) 1997-05-15
WO1992021382A1 (en) 1992-12-10
EP0586524B2 (de) 2000-11-02
DE69219331D1 (de) 1997-05-28
AU665198B2 (en) 1995-12-21
US5558857A (en) 1996-09-24
ES2103947T3 (es) 1997-10-01
AU1929192A (en) 1993-01-08
EP0586524A1 (de) 1994-03-16
DE69219331T2 (de) 1997-09-04
EP0586524B1 (de) 1997-04-23
JP3319754B2 (ja) 2002-09-03
US5569449A (en) 1996-10-29
FI935394A0 (fi) 1993-12-02
CA2110590A1 (en) 1992-12-10
ES2103947T5 (es) 2001-05-16
DK0586524T3 (de) 1997-05-20
IE921797A1 (en) 1992-12-16
NO934366L (no) 1993-12-01
FI935394A (fi) 1993-12-02

Similar Documents

Publication Publication Date Title
ATE151992T1 (de) Verbesserungen im bezug auf kontrastmittel
DE69326447T2 (de) Verbesserungen in bezug auf kontrastmittel
DK0620743T3 (da) Kontrastmidler bestående af galactosepartikler og en amfifil carboxylsyre
BR9406779A (pt) Complexos de inclusão de multicomponentes altamente solúveis contendo uma droga de tipo básico um ácido e uma ciclodextrina
DE69218241D1 (de) Arzneistofformulierung zur parenteralen anwendung
CA2090700A1 (en) Modified antibodies with controlled clearance time
FI940027A0 (fi) Parannuksia itse varjoaineisiin tai parannuksia, jotka liittyvät niihin
ATE324119T1 (de) Verwendung von saccharid-konjugaten
ES2174876T3 (es) Composiciones que comprenden proteinas relacionadas con el complementoy carbohidratos y metodos para producir y usar dichas composiciones.
DE68926708D1 (de) Von einem rezeptor induziertes kontrastmittel für den endocytose-typ mri
PT902783E (pt) Derivados hidrofobicos do taxano que promovem hidrolise
MD940199A (ro) Agenţi contrastanţi şi aplicarea acestora
BR9908716A (pt) Tratamento de disfunção sexual em certos grupos de pacientes
ES2110258T3 (es) Derivados de 1,3,5(10)-estratrieno activos por via oral.
FI932319A0 (fi) Foerbaettringar i till jordbruk anslutande och andra effekt foersedda anordningar
YU136390A (sh) Postupak za dobijanje supstituisanih 2-imidazolina
DE60107032D1 (de) Derivate von per(3,6-anhydro) cyclodextrinen, deren herstellung und verwendung zur abtrennung von ionen
KR920008035A (ko) 타이로신 유도체 및 그 제조방법
Jackson Apology
Fineman et al. The go-between.
Allen et al. Holy Root, Holy Branches
Zitkova et al. Lethality of Morphine, Pentazocine, Pethidine and Neostigmine in Mice Infected with Friend Virus or Toxoplasma Gondii
IT226149Z2 (it) " una busta almeno parzialmente trasparente, da impiegare nelle autovetture per la esposizione di documenti ed altro, e per impieghi equivalenti " .

Legal Events

Date Code Title Description
8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings
8339 Ceased/non-payment of the annual fee