DE69217900D1 - Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen - Google Patents

Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen

Info

Publication number
DE69217900D1
DE69217900D1 DE69217900T DE69217900T DE69217900D1 DE 69217900 D1 DE69217900 D1 DE 69217900D1 DE 69217900 T DE69217900 T DE 69217900T DE 69217900 T DE69217900 T DE 69217900T DE 69217900 D1 DE69217900 D1 DE 69217900D1
Authority
DE
Germany
Prior art keywords
drug delivery
manufacture
water
delivery systems
plastic cartridge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69217900T
Other languages
English (en)
Other versions
DE69217900T2 (de
Inventor
Peter Kuzma
Daniel Moro
Harry Quandt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indevus Pharmaceuticals Inc
Original Assignee
Valera Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valera Pharmaceuticals Inc filed Critical Valera Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69217900D1 publication Critical patent/DE69217900D1/de
Publication of DE69217900T2 publication Critical patent/DE69217900T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/02—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C41/04—Rotational or centrifugal casting, i.e. coating the inside of a mould by rotating the mould
    • B29C41/042—Rotational or centrifugal casting, i.e. coating the inside of a mould by rotating the mould by rotating a mould around its axis of symmetry
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C41/00—Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped article; Apparatus therefor
    • B29C41/34—Component parts, details or accessories; Auxiliary operations
    • B29C41/50—Shaping under special conditions, e.g. vacuum
DE69217900T 1992-01-14 1992-01-16 Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen Expired - Lifetime DE69217900T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU10183/92A AU651654B2 (en) 1992-01-14 1992-01-14 Manufacture of water-swellable hydrophilic articles and drug delivery devices
CA002059377A CA2059377C (en) 1992-01-14 1992-01-15 Manufacture of water-swellable hydrophilic articles and drug delivery devices
EP92300394A EP0551698B1 (de) 1992-01-14 1992-01-16 Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen
US08/041,523 US5292515A (en) 1990-09-28 1993-03-31 Manufacture of water-swellable hydrophilic articles and drug delivery devices

Publications (2)

Publication Number Publication Date
DE69217900D1 true DE69217900D1 (de) 1997-04-10
DE69217900T2 DE69217900T2 (de) 1997-06-12

Family

ID=27422426

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69217900T Expired - Lifetime DE69217900T2 (de) 1992-01-14 1992-01-16 Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen

Country Status (7)

Country Link
US (1) US5292515A (de)
EP (1) EP0551698B1 (de)
AT (1) ATE149345T1 (de)
AU (1) AU651654B2 (de)
CA (1) CA2059377C (de)
DE (1) DE69217900T2 (de)
DK (1) DK0551698T3 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5549924A (en) 1987-07-17 1996-08-27 Robin Renee Thill Shlenker Method of forming a membrane, especially a latex or polymer membrane, including a deactivating barrier and indicating layer
US5679399A (en) 1987-07-17 1997-10-21 Bio Barrier, Inc. Method of forming a membrane, especially a latex or polymer membrane, including multiple discrete layers
US5487739A (en) * 1987-11-17 1996-01-30 Brown University Research Foundation Implantable therapy systems and methods
US5662913A (en) * 1991-04-10 1997-09-02 Capelli; Christopher C. Antimicrobial compositions useful for medical applications
DK0585368T3 (da) 1991-04-25 1998-03-16 Univ Brown Res Found Implanterbart biokompatibelt immunisolatorisk vehikel til afgivelse af udvalgte terapeutiske produkter
US5800829A (en) * 1991-04-25 1998-09-01 Brown University Research Foundation Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
US6110481A (en) * 1994-03-04 2000-08-29 Trustees Of The Stevens Institute Of Technology Controlled release device based on aqueous-organic partitioning in porous membranes
US5876743A (en) * 1995-03-21 1999-03-02 Den-Mat Corporation Biocompatible adhesion in tissue repair
US5733565A (en) * 1996-02-23 1998-03-31 The Population Council, Center For Biomedical Research Male contraceptive implant
US6764690B2 (en) 1996-05-29 2004-07-20 Delsitech Oy Dissolvable oxides for biological applications
KR0181910B1 (ko) * 1996-06-20 1999-04-15 김광호 반도체 제조공정의 과산화수소수 온라인 분해방법 및 장치
US6200589B1 (en) 1996-09-13 2001-03-13 The University Of Akron Biological implants of semipermeable amphiphilic membranes
DK1041975T3 (da) 1997-12-22 2002-11-04 Alza Corp Hastighedskontrollerende membraner til anordninger til kontrolleret indførsel af medikament
US6117441A (en) * 1998-07-02 2000-09-12 The Population Council, Inc. Silicone core long term androgen delivery implant
CA2325386C (en) * 1999-01-28 2010-03-23 Hydromed Sciences A Division Of Gp Strategies Corporation Hydrogel compositions useful for the sustained release of macromolecules and methods of making same
WO2001012746A1 (en) * 1999-08-17 2001-02-22 Porex Technologies Corporation Self-sealing materials and devices comprising same
US6365171B1 (en) 1999-11-04 2002-04-02 The University Of Akron Amphiphilic networks, implantable immunoisolatory devices and methods of preparation
JP2003532556A (ja) * 2000-05-12 2003-11-05 ダルトン，ポール，ディー． 遠心力を用いて構造体を形成する方法
US6969480B2 (en) * 2000-05-12 2005-11-29 Matregen Corp. Method of producing structures using centrifugal forces
DE10210626A1 (de) * 2002-03-11 2003-09-25 Transmit Technologietransfer Verfahren zur Herstellung von Hohlfasern
US7811605B2 (en) * 2002-11-06 2010-10-12 Uluru Inc. Method of formation of shape-retentive aggregates of gel particles and their uses
US7351430B2 (en) * 2002-11-06 2008-04-01 Uluru Inc. Shape-retentive hydrogel particle aggregates and their uses
CA2437639C (en) 2003-08-11 2016-07-05 Valera Pharmaceuticals, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
US20090208540A1 (en) * 2003-08-11 2009-08-20 Indevus Pharmaceuticals, Inc. Implantable device for the delivery of naltrexone and methods of use thereof
US7858110B2 (en) 2003-08-11 2010-12-28 Endo Pharmaceuticals Solutions, Inc. Long term drug delivery devices with polyurethane based polymers and their manufacture
EP1756072A2 (de) * 2004-04-27 2007-02-28 Wyeth Reinigung von progesteronrezeptor-modulatoren
CA2570960C (en) * 2004-06-17 2013-10-01 Valera Pharmaceuticals, Inc. Compositions and methods for treating central precocious puberty
US7759312B2 (en) * 2005-03-11 2010-07-20 Endo Pharmaceuticals Solutions Inc. Delivery of dry formulations of octreotide
WO2006099288A2 (en) 2005-03-11 2006-09-21 Indevus Pharmaceuticals, Inc. Controlled release formulations of octreotide
FR2885512B1 (fr) * 2005-05-10 2007-08-10 Biocoral Inc Seringue pour bio-materiau
WO2006122414A1 (en) * 2005-05-17 2006-11-23 Matregen Corp. Depot for sustained and controlled delivery of methotrexate
US7910135B2 (en) * 2006-10-13 2011-03-22 Uluru Inc. Hydrogel wound dressing and biomaterials formed in situ and their uses
US20080228268A1 (en) * 2007-03-15 2008-09-18 Uluru, Inc. Method of Formation of Viscous, Shape Conforming Gels and Their Uses as Medical Prosthesis
WO2008134475A2 (en) * 2007-04-27 2008-11-06 Endo Pharmaceuticals Solutions Inc., 33 Implant device release agents and methods of using same
WO2009143404A1 (en) * 2008-05-23 2009-11-26 Wyeth Piperazine metabotropic glutamate receptor 5 (mglur5) negative allosteric modulators for anxiety/depression
US8071537B2 (en) 2008-06-25 2011-12-06 Endo Pharmaceuticals Solutions Inc. Implantable device for the sustained release of a polypeptide
JP5536053B2 (ja) * 2008-06-25 2014-07-02 エンド ファーマスーティカルズ ソリューションズ インコーポレイテッド． 離型剤を有するオクトレオチドインプラント
JP2012504139A (ja) * 2008-09-30 2012-02-16 エンド ファーマスーティカルズ ソリューションズ インコーポレイテッド． ヒストレリン送達用埋め込み可能型装置およびその使用方法
CA2739181C (en) * 2008-09-30 2017-03-14 Endo Pharmaceuticals Solutions Inc. Implantable device for the delivery of risperidone and methods of use thereof
AU2010314994B2 (en) 2009-11-09 2016-10-06 Spotlight Technology Partners Llc Fragmented hydrogels
WO2011057131A1 (en) 2009-11-09 2011-05-12 Spotlight Technology Partners Llc Polysaccharide based hydrogels
US8329219B2 (en) * 2009-12-22 2012-12-11 Cook Biotech Incorporated Methods for producing ECM-based biomaterials
US8360765B2 (en) * 2011-01-07 2013-01-29 Covidien Lp Systems and method for forming a coaxial implant
WO2012172449A1 (en) 2011-06-13 2012-12-20 Pfizer Inc. Lactams as beta secretase inhibitors
EP2771320B1 (de) 2011-10-24 2016-06-22 Endo Pharmaceuticals Inc. Cyclohexylamine
CN106029660B (zh) 2013-12-16 2019-11-15 阿萨纳生物科技有限责任公司 P2x3和/或p2x2/3化合物和方法
TW201642820A (zh) * 2015-02-19 2016-12-16 健生生物科技公司 細胞封裝加載裝置
US10126298B2 (en) 2015-05-04 2018-11-13 Arman Nabatian Hydrogels containing embedded substrates for targeted binding of molecules
CN106322042B (zh) * 2016-08-30 2018-10-30 江苏电科电气设备有限公司 一种预埋式熔管及其加工模具和加工方法
EP3528813A4 (de) 2016-09-30 2020-06-03 Asana BioSciences, LLC P2x3- und/oder p2x2/3-verbindungen und verfahren

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2265226A (en) * 1936-10-17 1941-12-09 Du Pont Cast resins having integral sheen
US2513014A (en) * 1946-11-18 1950-06-27 Abbott Lab Apparatus for implanting medicinal pellets subcutaneously
GB1306541A (en) * 1969-01-20 1973-02-14 Ceskoslovenska Akademie Ved Method of manufacturing tubes by centrifugal casting
US3921632A (en) * 1974-08-16 1975-11-25 Frank M Bardani Implant device
US4959217A (en) * 1986-05-22 1990-09-25 Syntex (U.S.A.) Inc. Delayed/sustained release of macromolecules
US4871094A (en) * 1986-12-31 1989-10-03 Alcon Laboratories, Inc. Means and method for dispensing substances
US4994028A (en) * 1987-03-18 1991-02-19 Endocon, Inc. Injector for inplanting multiple pellet medicaments
US4846793A (en) * 1987-03-18 1989-07-11 Endocon, Inc. Injector for implanting multiple pellet medicaments
US5035891A (en) * 1987-10-05 1991-07-30 Syntex (U.S.A.) Inc. Controlled release subcutaneous implant
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
JPH0818971B2 (ja) * 1989-02-16 1996-02-28 ブリティッシュ・テクノロジー・グループ・リミテッド 投与製剤

Also Published As

Publication number Publication date
DE69217900T2 (de) 1997-06-12
EP0551698B1 (de) 1997-03-05
AU1018392A (en) 1993-07-15
DK0551698T3 (da) 1997-10-13
CA2059377C (en) 1996-08-27
AU651654B2 (en) 1994-07-28
US5292515A (en) 1994-03-08
EP0551698A1 (de) 1993-07-21
ATE149345T1 (de) 1997-03-15
CA2059377A1 (en) 1993-07-16

Similar Documents

Publication Publication Date Title
DE69217900D1 (de) Herstellung von in Wasser quellbaren hydrophilen Gegenständen sowie Arzneistoffabgabesystemen
US4865845A (en) Release rate adjustment of osmotic or diffusional delivery devices
US4900304A (en) Solid preparation administering instrument
US5906599A (en) Device for delivering biological agents
US3786812A (en) Contact lens for olar drug delivery
ATE66809T1 (de) Vorrichtung zur arzneistoffabgabe und verfahren zu ihrer herstellung.
DK156289D0 (da) Farmaceutisk praeparat indrettet til kontrolleret afgivelse af aktiv bestanddel
CA2033277A1 (en) Controlled release pharmaceutical preparation and method for producing the same
KR890003415A (ko) 이식제 투입장치
JPH06233810A (ja) 深部創傷用の円柱状創傷手当用物品
PT90343A (pt) Processo de preparacao de uma composicao de revestimento para um medicamento e respectivo dispositivo osmotico
NO2005021I1 (no) Leuprorelin acetat
AU587877B2 (en) An artificial gland for implantation in the human body
DE69331517D1 (de) Reibungsfreie infusionspumpe
IE44540L (en) Controlled release tablet
DE69212135T2 (de) Herstellung von homogenen Hydrogel-Copolymeren
JPS6128627Y2 (de)
RU1827266C (ru) Шприц одноразового использовани
Daniele et al. Glyceryl methacrylate hydrogel as a possible vitreous implant
NL7601017A (en) Ballistically implantable projectile for animals - for controlled sustained release of biologically active materials on contact with animal body fluids
NL7901919A (en) Polymer compsn. contg. physiologically active cpd. - with controlled release mixt., prepd. by polymerising monomers with radiation at below room temp. (NL 11.9.79)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: HYDRO MED SCIENCES, INC., WILMINGTON, DEL., US

8327 Change in the person/name/address of the patent owner

Owner name: INDEVUS PHARMACEUTICALS, INC., LEXINGTON, MASS, US