US5079353A
(en)
*
|
1987-12-02 |
1992-01-07 |
Chembiomed, Ltd. |
Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
|
EP0588848A1
(de)
*
|
1991-06-10 |
1994-03-30 |
Glycomed Incorporated |
Modifizierte sialyl lewis a verbindungen
|
CA2110797C
(en)
*
|
1991-06-10 |
2001-02-20 |
Andre P. Venot |
Modified sialyl lewis x compounds
|
SK42594A3
(en)
|
1991-10-15 |
1994-10-05 |
Scripps Research Inst |
Method of production of fucosylated carbohydrates
|
WO1994010340A1
(en)
*
|
1992-10-30 |
1994-05-11 |
Mt. Sinai Hospital Corporation |
Method for measuring glycosyltransferase activity
|
US6406894B1
(en)
|
1992-12-11 |
2002-06-18 |
Glycorex Ab |
Process for preparing polyvalent and physiologically degradable carbohydrate-containing polymers by enzymatic glycosylation reactions and the use thereof for preparing carbohydrate building blocks
|
US5811404A
(en)
*
|
1993-05-14 |
1998-09-22 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
US5854218A
(en)
*
|
1993-05-14 |
1998-12-29 |
Cytel Corporation |
Sialyl Lex analogues as inhibitors of cellular adhesion
|
JPH08510729A
(ja)
*
|
1993-05-14 |
1996-11-12 |
サイテル コーポレイション |
細胞接着のインヒビターとしてのシアリルLe▲上x▼類似体
|
US5559103A
(en)
*
|
1993-07-21 |
1996-09-24 |
Cytel Corporation |
Bivalent sialyl X saccharides
|
DE4431280A1
(de)
|
1994-09-02 |
1996-03-07 |
Hoechst Ag |
Verfahren zur Isolierung und Reinigung von nukleotidaktivierten Zuckern aus biologischen Quellen
|
US5545553A
(en)
*
|
1994-09-26 |
1996-08-13 |
The Rockefeller University |
Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them
|
US6030815A
(en)
*
|
1995-04-11 |
2000-02-29 |
Neose Technologies, Inc. |
Enzymatic synthesis of oligosaccharides
|
US5728554A
(en)
*
|
1995-04-11 |
1998-03-17 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
US5876980A
(en)
*
|
1995-04-11 |
1999-03-02 |
Cytel Corporation |
Enzymatic synthesis of oligosaccharides
|
US5922577A
(en)
*
|
1995-04-11 |
1999-07-13 |
Cytel Corporation |
Enzymatic synthesis of glycosidic linkages
|
CA2231073A1
(en)
*
|
1995-09-29 |
1997-04-10 |
Ossi Renkonen |
Synthetic multivalent slex containing polylactosamines and methods for use
|
AUPN658795A0
(en)
*
|
1995-11-15 |
1995-12-07 |
Commonwealth Scientific And Industrial Research Organisation |
Method of producing alpha 2, 3 sialyltransferase
|
US6841543B1
(en)
*
|
1996-01-31 |
2005-01-11 |
President And Fellows Of Harvard College |
Methods of inhibiting production of T helper type 2 cytokines in human immune cells
|
WO1997037682A1
(en)
*
|
1996-04-10 |
1997-10-16 |
Cytel Corporation |
Nucleic acids encoding gdp-fucose pyrophosphorylase
|
ATE304546T1
(de)
*
|
1996-10-10 |
2005-09-15 |
Neose Technologies Inc |
Reinigung von kohlenhydraten mittels umkehrosmose und nanofiltration
|
WO1998031826A1
(en)
*
|
1997-01-16 |
1998-07-23 |
Cytel Corporation |
Practical in vitro sialylation of recombinant glycoproteins
|
US6191271B1
(en)
|
1997-09-05 |
2001-02-20 |
Glycim Oy |
Synthetic divalent sLex containing polylactosamines and methods for use
|
EP1903114A3
(de)
|
1997-12-01 |
2008-07-23 |
Neose Technologies, Inc. |
Enzymatische Synthese von Gangliosiden
|
US7244601B2
(en)
*
|
1997-12-15 |
2007-07-17 |
National Research Council Of Canada |
Fusion proteins for use in enzymatic synthesis of oligosaccharides
|
US6500661B1
(en)
*
|
1998-01-15 |
2002-12-31 |
Neose Technologies, Inc. |
Enzymatic conversion of GDP-mannose to GDP-fucose
|
US6689604B1
(en)
*
|
1998-03-20 |
2004-02-10 |
National Research Council Of Canada |
Lipopolysaccharide α-2,3 sialyltransferase of Campylobacter jejuni and its uses
|
US6194178B1
(en)
|
1998-09-03 |
2001-02-27 |
Synsorb Biotech Inc. |
Method for the production of sialylated oligosaccharides
|
US6503744B1
(en)
*
|
1999-02-01 |
2003-01-07 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
US6699705B2
(en)
*
|
1999-02-01 |
2004-03-02 |
National Research Council Of Canada |
Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
|
WO2002016438A2
(en)
*
|
2000-08-22 |
2002-02-28 |
National Research Council Of Canada |
Synthesis of complex carbohydrates
|
EP1425408A4
(de)
|
2001-08-17 |
2004-11-10 |
Neose Technologies Inc |
Chemoenzymatische synthese sialylierter oligosaccharide
|
US7696163B2
(en)
|
2001-10-10 |
2010-04-13 |
Novo Nordisk A/S |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7399613B2
(en)
*
|
2001-10-10 |
2008-07-15 |
Neose Technologies, Inc. |
Sialic acid nucleotide sugars
|
US7297511B2
(en)
*
|
2001-10-10 |
2007-11-20 |
Neose Technologies, Inc. |
Interferon alpha: remodeling and glycoconjugation of interferon alpha
|
US7265084B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
EP2305311A3
(de)
|
2001-10-10 |
2011-07-20 |
BioGeneriX AG |
Glykokonjugation von Peptiden
|
US7439043B2
(en)
*
|
2001-10-10 |
2008-10-21 |
Neose Technologies, Inc. |
Galactosyl nucleotide sugars
|
US7214660B2
(en)
|
2001-10-10 |
2007-05-08 |
Neose Technologies, Inc. |
Erythropoietin: remodeling and glycoconjugation of erythropoietin
|
US7125843B2
(en)
*
|
2001-10-19 |
2006-10-24 |
Neose Technologies, Inc. |
Glycoconjugates including more than one peptide
|
US7265085B2
(en)
*
|
2001-10-10 |
2007-09-04 |
Neose Technologies, Inc. |
Glycoconjugation methods and proteins/peptides produced by the methods
|
US8008252B2
(en)
*
|
2001-10-10 |
2011-08-30 |
Novo Nordisk A/S |
Factor VII: remodeling and glycoconjugation of Factor VII
|
ES2411007T3
(es)
|
2001-10-10 |
2013-07-04 |
Novo Nordisk A/S |
Remodelación y glicoconjugación de péptidos
|
US7179617B2
(en)
|
2001-10-10 |
2007-02-20 |
Neose Technologies, Inc. |
Factor IX: remolding and glycoconjugation of Factor IX
|
US7157277B2
(en)
*
|
2001-11-28 |
2007-01-02 |
Neose Technologies, Inc. |
Factor VIII remodeling and glycoconjugation of Factor VIII
|
US7795210B2
(en)
|
2001-10-10 |
2010-09-14 |
Novo Nordisk A/S |
Protein remodeling methods and proteins/peptides produced by the methods
|
US7226903B2
(en)
*
|
2001-10-10 |
2007-06-05 |
Neose Technologies, Inc. |
Interferon beta: remodeling and glycoconjugation of interferon beta
|
US7173003B2
(en)
|
2001-10-10 |
2007-02-06 |
Neose Technologies, Inc. |
Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
|
US7473680B2
(en)
*
|
2001-11-28 |
2009-01-06 |
Neose Technologies, Inc. |
Remodeling and glycoconjugation of peptides
|
AU2003225791A1
(en)
*
|
2002-03-15 |
2003-09-29 |
Department Of Veterans Affairs, Rehabilitation R And D Service |
Methods and compositions for directing cells to target organs
|
AU2003249641B2
(en)
*
|
2002-05-16 |
2009-08-20 |
Glycomimetics, Inc. |
Compounds and methods for inhibiting selectin-mediated function
|
MXPA04012496A
(es)
|
2002-06-21 |
2005-09-12 |
Novo Nordisk Healthcare Ag |
Glicoformos del factor vii pegilados.
|
WO2004004636A2
(en)
*
|
2002-07-03 |
2004-01-15 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis
|
AU2003287091B2
(en)
*
|
2002-10-10 |
2010-04-08 |
U.S. Government As Represented By The Department Of Veterans Affairs |
Detection, localization and staging of tumors using labeled activated lymphocytes directed to a tumor specific epitope
|
CN100351260C
(zh)
|
2002-11-12 |
2007-11-28 |
布赖汉姆妇女医院 |
葡萄球菌感染的多糖疫苗
|
WO2004080960A2
(en)
|
2003-03-06 |
2004-09-23 |
Neose Technologies Inc. |
Methods and compositions for the enzymatic synthesis of gangliosides
|
WO2004083258A2
(en)
|
2003-03-14 |
2004-09-30 |
Neose Technologies Inc. |
Branched water-soluble polymers and their conjugates
|
US8791070B2
(en)
|
2003-04-09 |
2014-07-29 |
Novo Nordisk A/S |
Glycopegylated factor IX
|
EP1613261A4
(de)
*
|
2003-04-09 |
2011-01-26 |
Novo Nordisk As |
Intrazelluläre bildung von peptidkonjugaten
|
CA2522345A1
(en)
|
2003-04-09 |
2004-11-18 |
Neose Technologies, Inc. |
Glycopegylation methods and proteins/peptides produced by the methods
|
US20040219158A1
(en)
*
|
2003-05-02 |
2004-11-04 |
Glycomimetics, Inc. |
Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria
|
WO2004103275A2
(en)
|
2003-05-09 |
2004-12-02 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of human growth hormone glycosylation mutants
|
WO2005012484A2
(en)
|
2003-07-25 |
2005-02-10 |
Neose Technologies, Inc. |
Antibody-toxin conjugates
|
KR101113726B1
(ko)
*
|
2003-08-12 |
2012-02-27 |
리폭센 테크놀로지즈 리미티드 |
단백질 유도 및 컨쥬게이션용 시알산 유도체
|
WO2005051920A2
(en)
*
|
2003-11-19 |
2005-06-09 |
Glycomimetics, Inc. |
Specific antagonist for both e- and p-selectins
|
US20050187171A1
(en)
*
|
2003-11-19 |
2005-08-25 |
Glycomimetics, Inc. |
Glycomimetic antagonists for both E-and P-selectins
|
US20080305992A1
(en)
|
2003-11-24 |
2008-12-11 |
Neose Technologies, Inc. |
Glycopegylated erythropoietin
|
AU2004293103C1
(en)
*
|
2003-11-24 |
2010-12-02 |
Ratiopharm Gmbh |
Glycopegylated erythropoietin
|
US8633157B2
(en)
|
2003-11-24 |
2014-01-21 |
Novo Nordisk A/S |
Glycopegylated erythropoietin
|
US7956032B2
(en)
*
|
2003-12-03 |
2011-06-07 |
Novo Nordisk A/S |
Glycopegylated granulocyte colony stimulating factor
|
US20060040856A1
(en)
*
|
2003-12-03 |
2006-02-23 |
Neose Technologies, Inc. |
Glycopegylated factor IX
|
US20080318850A1
(en)
*
|
2003-12-03 |
2008-12-25 |
Neose Technologies, Inc. |
Glycopegylated Factor Ix
|
WO2005070138A2
(en)
|
2004-01-08 |
2005-08-04 |
Neose Technologies, Inc. |
O-linked glycosylation of peptides
|
NZ548893A
(en)
|
2004-02-04 |
2009-09-25 |
Biogernerix Ag |
Methods of refolding mammalian glycosyltransferases
|
RU2006138181A
(ru)
*
|
2004-05-04 |
2008-06-10 |
Ново Нордиск Хелс Кеа Аг (Ch) |
О-связанные гликоформы полипептидов и способ их изготовления
|
WO2006010143A2
(en)
|
2004-07-13 |
2006-01-26 |
Neose Technologies, Inc. |
Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
|
WO2006031811A2
(en)
|
2004-09-10 |
2006-03-23 |
Neose Technologies, Inc. |
Glycopegylated interferon alpha
|
WO2006035057A1
(en)
*
|
2004-09-29 |
2006-04-06 |
Novo Nordisk Health Care Ag |
Modified proteins
|
ES2566670T3
(es)
|
2004-10-29 |
2016-04-14 |
Ratiopharm Gmbh |
Remodelación y glucopegilación del factor de crecimiento de fibroblastos (FGF)
|
AU2006203792B2
(en)
|
2005-01-10 |
2011-11-03 |
Ratiopharm Gmbh |
Glycopegylated Granulocyte Colony Stimulating Factor
|
WO2006105426A2
(en)
*
|
2005-03-30 |
2006-10-05 |
Neose Technologies, Inc. |
Manufacturing process for the production of peptides grown in insect cell lines
|
US20070154992A1
(en)
*
|
2005-04-08 |
2007-07-05 |
Neose Technologies, Inc. |
Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
|
US20090036386A1
(en)
*
|
2005-05-25 |
2009-02-05 |
Glycomimetics, Inc |
Heterobifunctional compounds for selectin inhibition
|
JP5216580B2
(ja)
|
2005-05-25 |
2013-06-19 |
ノヴォ ノルディスク アー/エス |
グリコペグ化第ix因子
|
EP1888098A2
(de)
|
2005-05-25 |
2008-02-20 |
Neose Technologies, Inc. |
Glykopegylierte erythropoetin-formulierungen
|
AU2006280101B2
(en)
*
|
2005-08-09 |
2012-06-28 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of the PA-IL lectin, PA-IIL lectin or both the lectins from Pseudomonas
|
CN102719508A
(zh)
*
|
2005-08-19 |
2012-10-10 |
诺和诺德公司 |
糖基聚乙二醇化的因子vii和因子viia
|
US20070105755A1
(en)
*
|
2005-10-26 |
2007-05-10 |
Neose Technologies, Inc. |
One pot desialylation and glycopegylation of therapeutic peptides
|
PL2264043T3
(pl)
*
|
2005-09-02 |
2018-04-30 |
Glycomimetics, Inc. |
Heterobifunkcyjne inhibitory pan-selektyny
|
US20090048440A1
(en)
*
|
2005-11-03 |
2009-02-19 |
Neose Technologies, Inc. |
Nucleotide Sugar Purification Using Membranes
|
WO2007143052A1
(en)
*
|
2006-06-01 |
2007-12-13 |
Glycomimetics, Inc. |
Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas
|
US20080274958A1
(en)
*
|
2006-07-21 |
2008-11-06 |
Neose Technologies, Inc. |
Glycosylation of peptides via o-linked glycosylation sequences
|
WO2008057683A2
(en)
|
2006-10-03 |
2008-05-15 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
RU2460543C2
(ru)
|
2006-10-04 |
2012-09-10 |
Ново Нордиск А/С |
Глицерин-связанные пэгилированные сахара и гликопептиды
|
CA2666103C
(en)
|
2006-10-12 |
2014-02-18 |
Glycomimetics, Inc. |
Glycomimetic replacements for hexoses and n-acetyl hexosamines
|
US20080207487A1
(en)
*
|
2006-11-02 |
2008-08-28 |
Neose Technologies, Inc. |
Manufacturing process for the production of polypeptides expressed in insect cell-lines
|
NZ598863A
(en)
*
|
2007-02-09 |
2013-11-29 |
Glycomimetics Inc |
Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines
|
CA2682897C
(en)
|
2007-04-03 |
2016-11-22 |
Biogenerix Ag |
Methods of treatment using glycopegylated g-csf
|
US20090053167A1
(en)
*
|
2007-05-14 |
2009-02-26 |
Neose Technologies, Inc. |
C-, S- and N-glycosylation of peptides
|
EP2170919B8
(de)
|
2007-06-12 |
2016-01-20 |
ratiopharm GmbH |
Verbessertes verfahren zur herstellung von nukleotidzuckern
|
US8039442B2
(en)
|
2007-07-18 |
2011-10-18 |
Glycomimetics, Inc. |
Compounds and methods for treatment of sickle cell disease or complications associated therewith
|
US8207112B2
(en)
|
2007-08-29 |
2012-06-26 |
Biogenerix Ag |
Liquid formulation of G-CSF conjugate
|
EP2626080A3
(de)
|
2008-02-27 |
2014-03-05 |
Novo Nordisk A/S |
Konjugierte Faktor-VIII-Moleküle
|
WO2009126556A1
(en)
|
2008-04-08 |
2009-10-15 |
Glycomimetics, Inc. |
Pan-selectin inhibitor with enhanced pharmacokinetic activity
|
KR101529061B1
(ko)
|
2008-05-30 |
2015-06-16 |
모멘타 파머슈티컬스 인코포레이티드 |
당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
|
EP2318015B1
(de)
*
|
2008-06-13 |
2013-08-07 |
GlycoMimetics, Inc. |
Behandlung von blutkrebs mit ausgewählten glykomimetischen verbindungen
|
RU2532911C2
(ru)
|
2008-07-21 |
2014-11-20 |
Дзе Брихэм Энд Уимен'З Хоспитал, Инк. |
Способы и композиции, относящиеся к синтетическим бета-1,6-глюкозаминолигосахаридам
|
CA2760292A1
(en)
*
|
2009-05-01 |
2010-11-04 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors
|
WO2012037034A1
(en)
|
2010-09-14 |
2012-03-22 |
Glycomimetics, Inc. |
E-selectin antagonists
|
PL2794626T6
(pl)
|
2011-12-22 |
2020-11-02 |
Glycomimetics, Inc. |
Związki antagonistyczne E-selektyny
|
EP2698636A1
(de)
*
|
2012-08-13 |
2014-02-19 |
Fundació Institut d'Investigació Biomèdica de Bellvitge |
Verfahren und Reagenzien zur Vorbeugung und/oder Behandlung von Transplantatabstoßung
|
PL2928476T3
(pl)
|
2012-12-07 |
2018-07-31 |
Glycomimetics, Inc. |
Związki, kompozycje i sposoby wykorzystujące antagonistów e-selektyny do mobilizacji komórek hematopoietycznych
|
AU2015355136B2
(en)
|
2014-12-03 |
2020-06-25 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors
|
CA3009836A1
(en)
|
2016-01-22 |
2017-07-27 |
Glycomimetics, Inc. |
Glycomimetic inhibitors of pa-il and pa-iil lectins
|
US11291678B2
(en)
|
2016-03-02 |
2022-04-05 |
Glycomimetics, Inc |
Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin
|
WO2018031445A1
(en)
|
2016-08-08 |
2018-02-15 |
Glycomimetics, Inc. |
Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4
|
BR112019006642A2
(pt)
|
2016-10-07 |
2019-07-02 |
Glycomimetics Inc |
antagonistas multiméricos de e-selectina altamente potentes
|
JP7272956B2
(ja)
|
2017-03-15 |
2023-05-12 |
グリコミメティクス, インコーポレイテッド |
E-セレクチンアンタゴニストとしてのガラクトピラノシル-シクロヘキシル誘導体
|
JP7275131B2
(ja)
|
2017-11-30 |
2023-05-17 |
グリコミメティクス, インコーポレイテッド |
骨髄浸潤リンパ球を動員する方法、およびその使用
|
JP7304863B2
(ja)
|
2017-12-29 |
2023-07-07 |
グリコミメティクス, インコーポレイテッド |
E-セレクチンおよびガレクチン-3のヘテロ二機能性阻害剤
|
JP7455064B2
(ja)
|
2018-03-05 |
2024-03-25 |
グリコミメティクス, インコーポレイテッド |
急性骨髄性白血病および関連状態を処置する方法
|
US11845771B2
(en)
|
2018-12-27 |
2023-12-19 |
Glycomimetics, Inc. |
Heterobifunctional inhibitors of E-selectin and galectin-3
|
CN115343485B
(zh)
*
|
2022-10-18 |
2023-01-06 |
天津德祥生物技术股份有限公司 |
血型抗原三糖偶联物在血型抗体检测中的应用
|