DE69217031T2 - Verapamiltablette mit kontrollierter freisetzung - Google Patents

Verapamiltablette mit kontrollierter freisetzung

Info

Publication number
DE69217031T2
DE69217031T2 DE69217031T DE69217031T DE69217031T2 DE 69217031 T2 DE69217031 T2 DE 69217031T2 DE 69217031 T DE69217031 T DE 69217031T DE 69217031 T DE69217031 T DE 69217031T DE 69217031 T2 DE69217031 T2 DE 69217031T2
Authority
DE
Germany
Prior art keywords
controlled release
verapamil
tablet
verapamil tablet
tablets
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69217031T
Other languages
English (en)
Other versions
DE69217031D1 (de
Inventor
Anand Baichwal
John Staniforth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Penwest Pharmaceuticals Co
Original Assignee
Mendell Edward Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mendell Edward Co Inc filed Critical Mendell Edward Co Inc
Publication of DE69217031D1 publication Critical patent/DE69217031D1/de
Application granted granted Critical
Publication of DE69217031T2 publication Critical patent/DE69217031T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Separation By Low-Temperature Treatments (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cephalosporin Compounds (AREA)
DE69217031T 1991-07-25 1992-07-02 Verapamiltablette mit kontrollierter freisetzung Expired - Fee Related DE69217031T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/736,031 US5169639A (en) 1988-09-19 1991-07-25 Controlled release verapamil tablets
PCT/US1992/005712 WO1993001803A1 (en) 1991-07-25 1992-07-02 Controlled release verapamil tablet

Publications (2)

Publication Number Publication Date
DE69217031D1 DE69217031D1 (de) 1997-03-06
DE69217031T2 true DE69217031T2 (de) 1997-05-07

Family

ID=24958214

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69217031T Expired - Fee Related DE69217031T2 (de) 1991-07-25 1992-07-02 Verapamiltablette mit kontrollierter freisetzung

Country Status (17)

Country Link
US (1) US5169639A (de)
EP (1) EP0550737B1 (de)
JP (1) JPH0733339B2 (de)
KR (1) KR0184308B1 (de)
AT (1) ATE147974T1 (de)
AU (1) AU649163B2 (de)
CA (1) CA2092287C (de)
DE (1) DE69217031T2 (de)
DK (1) DK0550737T3 (de)
ES (1) ES2099273T3 (de)
FI (1) FI107231B (de)
GR (1) GR3023086T3 (de)
HU (1) HU218658B (de)
IE (1) IE922411A1 (de)
IL (1) IL102614A (de)
MX (1) MX9204352A (de)
WO (1) WO1993001803A1 (de)

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US6726930B1 (en) * 1993-09-09 2004-04-27 Penwest Pharmaceuticals Co. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5773025A (en) * 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6746691B2 (en) 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US6676967B1 (en) 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
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AU2068797A (en) * 1996-01-29 1997-08-20 Edward Mendell Co. Inc. Sustained release excipient
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JP3148256B2 (ja) 1996-07-08 2001-03-19 エドワード メンデル カンパニー．，インコーポレーテッド 高用量難溶性薬物用持続放出マトリックス
IN186245B (de) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
US6056977A (en) 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
JP2002531491A (ja) * 1998-12-11 2002-09-24 ノストラム・ファーマスーティカルズ・インコーポレイテッド ヒドロコロイドおよびセルロースエーテルを含む持続放出性錠剤
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
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DE60038536T2 (de) * 1999-09-30 2009-06-10 Penwest Pharmaceuticals Co. Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe
US6500462B1 (en) 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
BR0115585A (pt) 2000-11-28 2005-12-13 Fmc Corp Composições de revestimento de pronta liberação, endurecìvel, comestìvel, seca e, úmida, forma de dosagem sólida, e, método para revestir uma forma de dosagem sólida farmacêutica ou veterinária, confeito, semente, ração animal, fertilizante, comprimido de pesticida ou alimento
US20030190360A1 (en) 2001-03-13 2003-10-09 Baichwal Anand R. Chronotherapeutic dosage forms containing glucocorticosteroid and methods of treatment
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CN1610551A (zh) 2001-07-06 2005-04-27 恩德制药公司 用作止痛剂的6－羟基羟吗啡酮的肠胃外给药
AU2003230805A1 (en) * 2002-04-05 2003-10-27 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
US20040005359A1 (en) * 2002-06-27 2004-01-08 Cheng Xiu Xiu Controlled release oral dosage form
EP1549296A4 (de) * 2002-08-02 2006-08-09 Penwest Pharmaceuticals Co Metformin-formulierungen mit verzögerter freisetzung
NZ545921A (en) 2003-09-19 2009-09-25 Penwest Pharmaceuticals Co Delayed released dosage forms
CN101578096A (zh) * 2006-10-10 2009-11-11 潘威斯脱药物公司 稳健的缓释制剂
JP5463537B2 (ja) * 2008-02-22 2014-04-09 ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 分離方法
US20100159001A1 (en) * 2008-12-19 2010-06-24 Cardinal John R Extended-Release Pharmaceutical Formulations
US20100160363A1 (en) * 2008-12-19 2010-06-24 Aaipharma Services Corp. Extended-release pharmaceutical formulations

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Also Published As

Publication number Publication date
EP0550737A1 (de) 1993-07-14
JPH0733339B2 (ja) 1995-04-12
EP0550737B1 (de) 1997-01-22
HU218658B (hu) 2000-10-28
IL102614A0 (en) 1993-01-14
JPH06500576A (ja) 1994-01-20
FI107231B (fi) 2001-06-29
ATE147974T1 (de) 1997-02-15
FI931342A (fi) 1993-03-25
CA2092287C (en) 1997-03-25
DE69217031D1 (de) 1997-03-06
IL102614A (en) 1997-02-18
KR930701983A (ko) 1993-09-08
EP0550737A4 (en) 1993-12-15
AU2403392A (en) 1993-02-23
MX9204352A (es) 1993-04-01
WO1993001803A1 (en) 1993-02-04
ES2099273T3 (es) 1997-05-16
US5169639A (en) 1992-12-08
HU9300768D0 (en) 1993-06-28
KR0184308B1 (ko) 1999-05-01
DK0550737T3 (de) 1997-02-17
FI931342A0 (fi) 1993-03-25
HUT64221A (en) 1993-12-28
GR3023086T3 (en) 1997-07-30
AU649163B2 (en) 1994-05-12
IE922411A1 (en) 1993-01-27
CA2092287A1 (en) 1993-01-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PENWEST PHARMACEUTICALS CO., PATTERSON, N.Y., US

8339 Ceased/non-payment of the annual fee