DE69211371T2 - Bestimmung von Analyten mit hohem Molekulargewicht - Google Patents

Bestimmung von Analyten mit hohem Molekulargewicht

Info

Publication number
DE69211371T2
DE69211371T2 DE69211371T DE69211371T DE69211371T2 DE 69211371 T2 DE69211371 T2 DE 69211371T2 DE 69211371 T DE69211371 T DE 69211371T DE 69211371 T DE69211371 T DE 69211371T DE 69211371 T2 DE69211371 T2 DE 69211371T2
Authority
DE
Germany
Prior art keywords
determination
molecular weight
high molecular
weight analytes
analytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69211371T
Other languages
English (en)
Other versions
DE69211371D1 (de
Inventor
Rueyming Loor
Jeff Shindelman
Pyare L Khanna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Microgenics Corp
Original Assignee
Microgenics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microgenics Corp filed Critical Microgenics Corp
Publication of DE69211371D1 publication Critical patent/DE69211371D1/de
Application granted granted Critical
Publication of DE69211371T2 publication Critical patent/DE69211371T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
DE69211371T 1991-02-01 1992-01-31 Bestimmung von Analyten mit hohem Molekulargewicht Expired - Fee Related DE69211371T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/649,483 US5244785A (en) 1991-02-01 1991-02-01 Determination of high molecular weight analytes using a β-galactosidase complementation assay

Publications (2)

Publication Number Publication Date
DE69211371D1 DE69211371D1 (de) 1996-07-18
DE69211371T2 true DE69211371T2 (de) 1996-11-28

Family

ID=24604988

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69211371T Expired - Fee Related DE69211371T2 (de) 1991-02-01 1992-01-31 Bestimmung von Analyten mit hohem Molekulargewicht

Country Status (7)

Country Link
US (1) US5244785A (de)
EP (1) EP0497613B1 (de)
JP (1) JP2892879B2 (de)
AU (1) AU653196B2 (de)
CA (1) CA2060377A1 (de)
DE (1) DE69211371T2 (de)
ES (1) ES2090492T3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612019A (en) * 1988-12-19 1997-03-18 Gordon, Deceased; David Diagnosis and treatment of HIV viral infection using magnetic metal transferrin particles
CA2068190C (en) * 1991-05-15 1996-12-17 Microgenics Corporation Methods and compositions for enzyme complementation assays using the omega region of beta-galactosidase
DE4310141A1 (de) * 1993-03-29 1994-10-06 Boehringer Mannheim Gmbh Homobidentale trifunktionelle Linker
US5427912A (en) * 1993-08-27 1995-06-27 Boehringer Mannheim Corporation Electrochemical enzymatic complementation immunoassay
US5792617A (en) * 1994-08-18 1998-08-11 Rotman; M. Boris Cell proliferation-based amplified detection of analytes
US8795979B2 (en) 2011-01-18 2014-08-05 General Atomics Hydrolase enzyme substrates and uses thereof
CN110100180B (zh) * 2017-11-29 2022-04-29 深圳琅技生命科技有限公司 均相检测方法
JP7319959B2 (ja) * 2018-03-07 2023-08-02 大塚製薬株式会社 検体希釈液、試料の製造方法、試料、およびサンドイッチ法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334107A1 (fr) * 1975-12-05 1977-07-01 Pasteur Institut Procede de couplage de substances biologiques par des liaisons covalentes
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
WO1986002666A1 (en) * 1984-10-29 1986-05-09 Microgenics Corporation Methods for protein binding enzyme complementation assays
AU610281B2 (en) * 1987-09-21 1991-05-16 Roche Diagnostics Corporation Solid-phase non-separation enzyme assay
US4994385A (en) * 1987-10-30 1991-02-19 Abbott Laboratories Heterobifunctional coupling agents
US5037735A (en) * 1988-06-24 1991-08-06 Microgenics Corporation Visual discrimination qualitative enzyme complementation assay
SE8901566D0 (sv) * 1989-04-28 1989-04-28 Ferring Diagnostica Ab Nya peptider inkluderande en disulfidbindning
AU5664790A (en) * 1989-05-05 1990-11-29 Microgenics Corporation Method for protein binding enzyme complementation assays

Also Published As

Publication number Publication date
EP0497613A1 (de) 1992-08-05
AU1068792A (en) 1992-08-06
DE69211371D1 (de) 1996-07-18
JP2892879B2 (ja) 1999-05-17
US5244785A (en) 1993-09-14
CA2060377A1 (en) 1992-08-02
AU653196B2 (en) 1994-09-22
EP0497613B1 (de) 1996-06-12
ES2090492T3 (es) 1996-10-16
JPH0566223A (ja) 1993-03-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ROCHE DIAGNOSTICS CORP., INDIANAPOLIS, IND., US

8327 Change in the person/name/address of the patent owner

Owner name: MICROGENICS CORP.(N.D.GES.D.STAATES DELAWARE), FRE

8339 Ceased/non-payment of the annual fee