DE69210662D1 - Abstand zwischen Spitze und Oberfläche zur optimalen Abgeben einer Flüssigkeit - Google Patents

Abstand zwischen Spitze und Oberfläche zur optimalen Abgeben einer Flüssigkeit

Info

Publication number
DE69210662D1
DE69210662D1 DE69210662T DE69210662T DE69210662D1 DE 69210662 D1 DE69210662 D1 DE 69210662D1 DE 69210662 T DE69210662 T DE 69210662T DE 69210662 T DE69210662 T DE 69210662T DE 69210662 D1 DE69210662 D1 DE 69210662D1
Authority
DE
Germany
Prior art keywords
tip
distance
liquid
optimal dispensing
dispensing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69210662T
Other languages
English (en)
Other versions
DE69210662T2 (de
Inventor
James V Barry
Raymond F Jakubowicz
J Eric Hamann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Johnson and Johnson Clinical Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson and Johnson Clinical Diagnostics Inc filed Critical Johnson and Johnson Clinical Diagnostics Inc
Publication of DE69210662D1 publication Critical patent/DE69210662D1/de
Application granted granted Critical
Publication of DE69210662T2 publication Critical patent/DE69210662T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • G01N2035/00742Type of codes
    • G01N2035/00752Type of codes bar codes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016Control of the volume dispensed or introduced
    • G01N2035/102Preventing or detecting loss of fluid by dripping
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N2035/1025Fluid level sensing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1034Transferring microquantities of liquid
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/115831Condition or time responsive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/11Automated chemical analysis
    • Y10T436/119163Automated chemical analysis with aspirator of claimed structure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575Volumetric liquid transfer
DE69210662T 1991-03-21 1992-03-18 Abstand zwischen Spitze und Oberfläche zur optimalen Abgeben einer Flüssigkeit Expired - Lifetime DE69210662T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/672,980 US5143849A (en) 1991-03-21 1991-03-21 Tip to surface spacing for optimum dispensing controlled by a detected pressure change in the tip

Publications (2)

Publication Number Publication Date
DE69210662D1 true DE69210662D1 (de) 1996-06-20
DE69210662T2 DE69210662T2 (de) 1996-09-26

Family

ID=24700820

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69210662T Expired - Lifetime DE69210662T2 (de) 1991-03-21 1992-03-18 Abstand zwischen Spitze und Oberfläche zur optimalen Abgeben einer Flüssigkeit

Country Status (7)

Country Link
US (1) US5143849A (de)
EP (1) EP0505004B1 (de)
JP (1) JP3688723B2 (de)
KR (1) KR960009754B1 (de)
CA (1) CA2061044C (de)
DE (1) DE69210662T2 (de)
IE (1) IE920902A1 (de)

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US5312757A (en) * 1991-05-02 1994-05-17 Olympus Optical Co., Ltd. Sample distributing method
WO1993009668A1 (en) * 1991-11-22 1993-05-27 Affymax Technology N.V. Combinatorial strategies for polymer synthesis
US6943034B1 (en) 1991-11-22 2005-09-13 Affymetrix, Inc. Combinatorial strategies for polymer synthesis
US5456880A (en) * 1992-11-20 1995-10-10 Shimadzu Corporation Micropipet apparatus and micromanipulator
US5401467A (en) * 1993-07-21 1995-03-28 Eastman Kodak Company Whole blood metering cup
US5895761A (en) * 1993-07-21 1999-04-20 Clinical Diagnostic Systems, Inc. Surface area liquid transfer method and related apparatus
EP0635712B1 (de) * 1993-07-21 1998-01-14 Johnson & Johnson Clinical Diagnostics, Inc. Verfahren zur Vorbehandlung von diagnostischen Testelementen
DE4331997A1 (de) * 1993-09-21 1995-03-23 Boehringer Mannheim Gmbh Verfahren und System zur Mischung von Flüssigkeiten
DE4341229C2 (de) * 1993-12-03 1995-09-07 Eppendorf Geraetebau Netheler Pipettensystem
JP3351615B2 (ja) * 1994-03-17 2002-12-03 ソニー株式会社 液の境界検出方法と液分離方法
JP3420824B2 (ja) * 1994-04-15 2003-06-30 富士写真フイルム株式会社 乾式分析フイルム片への試料液点着方法およびその装置
JP3115501B2 (ja) * 1994-06-15 2000-12-11 プレシジョン・システム・サイエンス株式会社 分注機を利用した磁性体の脱着制御方法及びこの方法によって処理される各種装置
US7625697B2 (en) 1994-06-17 2009-12-01 The Board Of Trustees Of The Leland Stanford Junior University Methods for constructing subarrays and subarrays made thereby
US5601980A (en) * 1994-09-23 1997-02-11 Hewlett-Packard Company Manufacturing method and apparatus for biological probe arrays using vision-assisted micropipetting
JP3571092B2 (ja) * 1994-12-20 2004-09-29 富士写真フイルム株式会社 乾式分析フィルム片への試料液点着方法
CA2175001A1 (en) * 1995-05-01 1996-11-02 Andrew Shelley Foote Method of avoiding decreased-size first drops when aspirating from immersed rest conditions
US5611996A (en) * 1995-06-06 1997-03-18 Johnson & Johnson Clinical Diagnostics, Inc. Slide test element holder with minimized Z-axis variability
US5750881A (en) * 1995-07-13 1998-05-12 Chiron Diagnostics Corporation Method and apparatus for aspirating and dispensing sample fluids
US6158269A (en) * 1995-07-13 2000-12-12 Bayer Corporation Method and apparatus for aspirating and dispensing sample fluids
US5811306A (en) * 1995-09-04 1998-09-22 Fuji Photo Film Co., Ltd. Liquid spotting method
US5744099A (en) * 1995-09-15 1998-04-28 Cytek Development Inc. Apparatus for transfer of biological fluids
US5665601A (en) * 1996-01-22 1997-09-09 Johnson & Johnson Clinical Diagnostics, Inc. Avoiding bubble formation while sensing air-liquid interface using pressurized air flow
US6689323B2 (en) 1998-10-30 2004-02-10 Agilent Technologies Method and apparatus for liquid transfer
US6270726B1 (en) * 1999-09-30 2001-08-07 Dpc Cirrus, Inc. Tube bottom sensing for small fluid samples
DE10004941A1 (de) * 2000-02-06 2001-08-09 Reimer Offen Temperierter Probennehmer für Flüssigkeiten
DE10017790A1 (de) * 2000-04-10 2001-10-11 Basf Ag Verfahren zur Herstellung von Biopolymer-Feldern mit Echtzeitkontrolle
JP3926546B2 (ja) * 2000-09-22 2007-06-06 富士フイルム株式会社 点着検出方法および点着検出装置
EP1207396A1 (de) * 2000-10-20 2002-05-22 Seyonic SA Vorrichtung zum Abgeben von Flüssigkeit
US6484556B1 (en) * 2000-11-13 2002-11-26 Ortho Clinical Diagnostics, Inc. Thin film detection during fluid aspiration
KR100777362B1 (ko) * 2001-05-08 2007-11-19 (주)바이오니아 생물학적 시료의 미세 배열을 위한 스팟팅 핀
CA2490355A1 (en) * 2001-06-19 2002-12-27 B.C. Cancer Agency Microvolume liquid dispenser suitable for microarrays and methods related thereto
US6579724B2 (en) * 2001-09-13 2003-06-17 First Ten Angstroms Dispensing method and apparatus for dispensing very small quantities of fluid
US6937955B2 (en) 2002-03-29 2005-08-30 Ortho-Clinical Diagnostics, Inc. Method for automatic alignment of metering system for a clinical analyzer
US7955865B2 (en) * 2004-06-09 2011-06-07 The University Of British Columbia Reagent delivery apparatus and methods
JP4373427B2 (ja) 2005-11-15 2009-11-25 エフ.ホフマン−ラ ロシュ アーゲー 電気的滴下監視
EP1785731A1 (de) * 2005-11-15 2007-05-16 Roche Diagnostics GmbH Elektrische Tropfenüberwachung
US7457686B2 (en) 2007-03-14 2008-11-25 Ortho—Clinical Diagnostics, Inc. Robotic arm alignment
US9304141B2 (en) 2007-04-18 2016-04-05 Becton, Dickinson And Company Method and apparatus for determing dispense volume
EP2525230A4 (de) * 2010-01-13 2016-09-07 Hitachi High Tech Corp Automatisches analysegerät
CA2766735C (en) 2011-02-07 2020-06-02 Ortho-Clinical Diagnostics, Inc. Determining conditions in centrifuged blood using measured pressure
JP2013076674A (ja) * 2011-09-30 2013-04-25 Fujifilm Corp 分注装置および吸引ノズル位置制御方法
WO2014009251A1 (en) 2012-07-13 2014-01-16 Evotec Ag Method for adjusting the dispensing height of pipettes
CN105374253B (zh) * 2015-12-08 2018-08-10 辽宁石化职业技术学院 一种用于教学的多功能仪表校验装置及变送器校验方法
JP6807778B2 (ja) * 2017-03-06 2021-01-06 テラメックス株式会社 ピペットチップ先端検知装置、ピペットチップ先端検知プログラム
EP3381560A1 (de) * 2017-03-28 2018-10-03 Eppendorf AG Verfahren und dosiervorrichtung zum kontaktdosieren von flüssigkeiten
DE102020204670A1 (de) 2020-04-14 2021-10-14 Prime23 GmbH Vorrichtung und Verfahren zum Benetzen von biologischen Material mit wenigstens einer Flüssigkeit sowie eine Halteeinrichtung

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US4041995A (en) * 1975-01-30 1977-08-16 Eastman Kodak Company Gas pressure-activated drop dispenser
US4340390A (en) * 1980-06-16 1982-07-20 Eastman Kodak Company Method and apparatus for metering biological fluids
US4347875A (en) * 1980-07-14 1982-09-07 Eastman Kodak Company Self-cleaning nozzle construction for aspirators
JPS60155942A (ja) * 1984-01-25 1985-08-16 Fuji Photo Film Co Ltd 液体試料点着装置
US4794085A (en) * 1984-07-19 1988-12-27 Eastman Kodak Company Apparatus and method for detecting liquid penetration by a container used for aspirating and dispensing the liquid
US4586546A (en) * 1984-10-23 1986-05-06 Cetus Corporation Liquid handling device and method
US4675301A (en) * 1985-04-01 1987-06-23 Eastman Kodak Company Method for correcting for changes in air pressure above a liquid to be dispensed from a container mounted on a probe
US4615360A (en) * 1985-09-05 1986-10-07 Eastman Kodak Company Means providing separation of exterior sheath of liquid on dispensing tip
JPH076998B2 (ja) * 1987-12-04 1995-01-30 富士写真フイルム株式会社 自動分注器および点着方法
US5059393A (en) * 1989-01-05 1991-10-22 Eastman Kodak Company Analysis slide positioning apparatus and method for a chemical analyzer
DE69126690T2 (de) * 1990-04-06 1998-01-02 Perkin Elmer Corp Automatisiertes labor für molekularbiologie

Also Published As

Publication number Publication date
IE920902A1 (en) 1992-09-23
EP0505004A3 (en) 1992-12-30
CA2061044A1 (en) 1992-09-22
US5143849A (en) 1992-09-01
JP3688723B2 (ja) 2005-08-31
EP0505004B1 (de) 1996-05-15
DE69210662T2 (de) 1996-09-26
KR960009754B1 (en) 1996-07-24
CA2061044C (en) 1995-11-07
EP0505004A2 (de) 1992-09-23
JPH0599804A (ja) 1993-04-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN