DE69210588T2 - Molekulare genetische Identifikation unter Verwendung von Sonden, die polymorphe Orte erkennen - Google Patents
Molekulare genetische Identifikation unter Verwendung von Sonden, die polymorphe Orte erkennenInfo
- Publication number
- DE69210588T2 DE69210588T2 DE69210588T DE69210588T DE69210588T2 DE 69210588 T2 DE69210588 T2 DE 69210588T2 DE 69210588 T DE69210588 T DE 69210588T DE 69210588 T DE69210588 T DE 69210588T DE 69210588 T2 DE69210588 T2 DE 69210588T2
- Authority
- DE
- Germany
- Prior art keywords
- probes
- polymorphic sites
- molecular genetic
- genetic identification
- determination
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65051191A | 1991-02-05 | 1991-02-05 | |
PCT/US1992/000990 WO1992013971A1 (en) | 1991-02-05 | 1992-02-05 | Molecular genetic identification using probes that recognize polymorphic loci |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69210588D1 DE69210588D1 (de) | 1996-06-13 |
DE69210588T2 true DE69210588T2 (de) | 1996-09-19 |
Family
ID=24609233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69210588T Expired - Fee Related DE69210588T2 (de) | 1991-02-05 | 1992-02-05 | Molekulare genetische Identifikation unter Verwendung von Sonden, die polymorphe Orte erkennen |
Country Status (5)
Country | Link |
---|---|
US (1) | US5514547A (de) |
EP (1) | EP0570497B1 (de) |
AT (1) | ATE137808T1 (de) |
DE (1) | DE69210588T2 (de) |
WO (1) | WO1992013971A1 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5670325A (en) * | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
US5741650A (en) * | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
US6020137A (en) * | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US5928870A (en) * | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6100029A (en) * | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
US6146828A (en) * | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
US6268136B1 (en) | 1997-06-16 | 2001-07-31 | Exact Science Corporation | Methods for stool sample preparation |
US6406857B1 (en) | 1997-06-16 | 2002-06-18 | Exact Sciences Corporation | Methods for stool sample preparation |
US6544730B1 (en) | 1997-10-27 | 2003-04-08 | Prescott Deininger | High density polymorphic genetic locus |
US20020064792A1 (en) * | 1997-11-13 | 2002-05-30 | Lincoln Stephen E. | Database for storage and analysis of full-length sequences |
US6280947B1 (en) | 1999-08-11 | 2001-08-28 | Exact Sciences Corporation | Methods for detecting nucleotide insertion or deletion using primer extension |
US6503718B2 (en) | 1999-01-10 | 2003-01-07 | Exact Sciences Corporation | Methods for detecting mutations using primer extension for detecting disease |
US6153389A (en) * | 1999-02-22 | 2000-11-28 | Haarer; Brian K. | DNA additives as a mechanism for unambiguously marking biological samples |
DE60028732T2 (de) | 1999-02-25 | 2007-06-14 | Exact Sciences Corp., Maynard | Verfahren zur erhaltung der dns-integrität |
AU767983B2 (en) | 1999-04-09 | 2003-11-27 | Esoterix Genetic Laboratories, Llc | Methods for detecting nucleic acids indicative of cancer |
US6849403B1 (en) | 1999-09-08 | 2005-02-01 | Exact Sciences Corporation | Apparatus and method for drug screening |
US6586177B1 (en) * | 1999-09-08 | 2003-07-01 | Exact Sciences Corporation | Methods for disease detection |
CA2394921A1 (en) * | 1999-12-07 | 2001-06-14 | Anthony P. Shuber | Supracolonic aerodigestive neoplasm detection |
US6919174B1 (en) | 1999-12-07 | 2005-07-19 | Exact Sciences Corporation | Methods for disease detection |
WO2003071252A2 (en) | 2002-02-15 | 2003-08-28 | Exact Sciences Corporation | Methods for analysis of molecular events |
US20040259101A1 (en) * | 2003-06-20 | 2004-12-23 | Shuber Anthony P. | Methods for disease screening |
WO2005111244A2 (en) * | 2004-05-10 | 2005-11-24 | Exact Sciences Corporation | Methods for detecting a mutant nucleic acid |
WO2005113769A1 (en) * | 2004-05-14 | 2005-12-01 | Exact Sciences Corporation | Method for stabilizing biological samples for nucleic acid analysis |
US7981607B2 (en) * | 2004-08-27 | 2011-07-19 | Esoterix Genetic Laboratories LLC | Method for detecting recombinant event |
US9109256B2 (en) | 2004-10-27 | 2015-08-18 | Esoterix Genetic Laboratories, Llc | Method for monitoring disease progression or recurrence |
US9777314B2 (en) * | 2005-04-21 | 2017-10-03 | Esoterix Genetic Laboratories, Llc | Analysis of heterogeneous nucleic acid samples |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
ATE184317T1 (de) * | 1988-02-18 | 1999-09-15 | Univ Utah | Verwendung von dna-proben mit variabler anzahl von tandem-repetitiven stellen zur genetischen identifizierung |
US4963663A (en) * | 1988-12-23 | 1990-10-16 | University Of Utah | Genetic identification employing DNA probes of variable number tandem repeat loci |
NL8801147A (nl) * | 1988-05-02 | 1989-12-01 | Tno | Werkwijze voor het detecteren van genetische variatie, en daarvoor geschikte kit. |
WO1990002818A1 (en) * | 1988-09-08 | 1990-03-22 | Lifecodes Corporation | Probes for the detection of rflp in eucaryotic genomes |
US5192658A (en) * | 1989-03-30 | 1993-03-09 | Lifecodes Corporation | Compositions and protocols applicable to genetic analysis |
-
1992
- 1992-02-05 EP EP92906353A patent/EP0570497B1/de not_active Expired - Lifetime
- 1992-02-05 AT AT92906353T patent/ATE137808T1/de not_active IP Right Cessation
- 1992-02-05 DE DE69210588T patent/DE69210588T2/de not_active Expired - Fee Related
- 1992-02-05 WO PCT/US1992/000990 patent/WO1992013971A1/en active IP Right Grant
-
1994
- 1994-02-04 US US08/192,233 patent/US5514547A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69210588D1 (de) | 1996-06-13 |
EP0570497A1 (de) | 1993-11-24 |
EP0570497B1 (de) | 1996-05-08 |
WO1992013971A1 (en) | 1992-08-20 |
ATE137808T1 (de) | 1996-05-15 |
US5514547A (en) | 1996-05-07 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |