DE69131844T2 - Bildgebender Durchflusszytometer - Google Patents

Bildgebender Durchflusszytometer

Info

Publication number
DE69131844T2
DE69131844T2 DE69131844T DE69131844T DE69131844T2 DE 69131844 T2 DE69131844 T2 DE 69131844T2 DE 69131844 T DE69131844 T DE 69131844T DE 69131844 T DE69131844 T DE 69131844T DE 69131844 T2 DE69131844 T2 DE 69131844T2
Authority
DE
Germany
Prior art keywords
flow cytometer
imaging flow
imaging
cytometer
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131844T
Other languages
English (en)
Other versions
DE69131844D1 (de
Inventor
Shinichi Ogino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Publication of DE69131844D1 publication Critical patent/DE69131844D1/de
Application granted granted Critical
Publication of DE69131844T2 publication Critical patent/DE69131844T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G01N15/1433—
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1425—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its control arrangement
    • G01N15/1427—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459—Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434—Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/144—Imaging characterised by its optical setup
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765—Method using an image detector and processing of image signal
    • G01N2021/177—Detector of the video camera type
    • G01N2021/1772—Array detector
    • G01N2021/1774—Line array detector
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1789—Time resolved
    • G01N2021/1791—Time resolved stroboscopic; pulse gated; time range gated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
DE69131844T 1991-02-27 1991-09-04 Bildgebender Durchflusszytometer Expired - Fee Related DE69131844T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03033151A JP3121849B2 (ja) 1991-02-27 1991-02-27 フローイメージサイトメータ

Publications (2)

Publication Number Publication Date
DE69131844D1 DE69131844D1 (de) 2000-01-20
DE69131844T2 true DE69131844T2 (de) 2000-05-18

Family

ID=12378582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131844T Expired - Fee Related DE69131844T2 (de) 1991-02-27 1991-09-04 Bildgebender Durchflusszytometer

Country Status (5)

Country Link
US (1) US5247339A (de)
EP (1) EP0501005B1 (de)
JP (1) JP3121849B2 (de)
CA (1) CA2050761A1 (de)
DE (1) DE69131844T2 (de)

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US8406498B2 (en) 1999-01-25 2013-03-26 Amnis Corporation Blood and cell analysis using an imaging flow cytometer
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US6309886B1 (en) * 1999-06-04 2001-10-30 The Regents Of The University Of California High throughput analysis of samples in flowing liquid
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US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
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US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6934408B2 (en) * 2000-08-25 2005-08-23 Amnis Corporation Method and apparatus for reading reporter labeled beads
US6778263B2 (en) * 2000-08-25 2004-08-17 Amnis Corporation Methods of calibrating an imaging system using calibration beads
US6875973B2 (en) * 2000-08-25 2005-04-05 Amnis Corporation Auto focus for a flow imaging system
US6583865B2 (en) 2000-08-25 2003-06-24 Amnis Corporation Alternative detector configuration and mode of operation of a time delay integration particle analyzer
US6507391B2 (en) 2000-08-25 2003-01-14 Amnis Corporation Measuring the velocity of small moving objects such as cells
US6608680B2 (en) 2000-08-25 2003-08-19 Amnis Corporation TDI imaging system for kinetic studies
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WO2002031467A1 (en) 2000-10-12 2002-04-18 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
DE10052384B4 (de) * 2000-10-20 2011-02-10 Schwartz, Margit Vorrichtung und Verfahren zur Bestimmung von Partikeleigenschaften und/oder Partikelkonzentrationen in einem fluiden Medium
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
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US8953866B2 (en) 2004-03-16 2015-02-10 Amnis Corporation Method for imaging and differential analysis of cells
EP1800124B1 (de) 2004-03-16 2011-12-21 Amnis Corporation Auf bildlicher darstellung beruhende quantifizierung molekularer translokation
EP2801363B1 (de) 2004-03-29 2018-02-21 Inguran, LLC Verfahren zur lagerung von sortierten spermatozoen
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Also Published As

Publication number Publication date
EP0501005B1 (de) 1999-12-15
DE69131844D1 (de) 2000-01-20
JP3121849B2 (ja) 2001-01-09
EP0501005A2 (de) 1992-09-02
CA2050761A1 (en) 1992-08-28
EP0501005A3 (en) 1992-12-09
US5247339A (en) 1993-09-21
JPH04270963A (ja) 1992-09-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee