DE69131844D1 - Bildgebender Durchflusszytometer - Google Patents

Bildgebender Durchflusszytometer

Info

Publication number
DE69131844D1
DE69131844D1 DE69131844T DE69131844T DE69131844D1 DE 69131844 D1 DE69131844 D1 DE 69131844D1 DE 69131844 T DE69131844 T DE 69131844T DE 69131844 T DE69131844 T DE 69131844T DE 69131844 D1 DE69131844 D1 DE 69131844D1
Authority
DE
Germany
Prior art keywords
flow cytometer
imaging flow
imaging
cytometer
flow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131844T
Other languages
English (en)
Other versions
DE69131844T2 (de
Inventor
Shinichi Ogino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sysmex Corp
Original Assignee
Sysmex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sysmex Corp filed Critical Sysmex Corp
Application granted granted Critical
Publication of DE69131844D1 publication Critical patent/DE69131844D1/de
Publication of DE69131844T2 publication Critical patent/DE69131844T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G01N15/1433
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1425Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its control arrangement
    • G01N15/1427Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its control arrangement with the synchronisation of components, a time gate for operation of components, or suppression of particle coincidences
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1456Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals
    • G01N15/1459Electro-optical investigation, e.g. flow cytometers without spatial resolution of the texture or inner structure of the particle, e.g. processing of pulse signals the analysis being performed on a sample stream
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Electro-optical investigation, e.g. flow cytometers
    • G01N15/1434Electro-optical investigation, e.g. flow cytometers using an analyser being characterised by its optical arrangement
    • G01N2015/144Imaging characterised by its optical setup
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1765Method using an image detector and processing of image signal
    • G01N2021/177Detector of the video camera type
    • G01N2021/1772Array detector
    • G01N2021/1774Line array detector
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/1789Time resolved
    • G01N2021/1791Time resolved stroboscopic; pulse gated; time range gated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
DE69131844T 1991-02-27 1991-09-04 Bildgebender Durchflusszytometer Expired - Fee Related DE69131844T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03033151A JP3121849B2 (ja) 1991-02-27 1991-02-27 フローイメージサイトメータ

Publications (2)

Publication Number Publication Date
DE69131844D1 true DE69131844D1 (de) 2000-01-20
DE69131844T2 DE69131844T2 (de) 2000-05-18

Family

ID=12378582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131844T Expired - Fee Related DE69131844T2 (de) 1991-02-27 1991-09-04 Bildgebender Durchflusszytometer

Country Status (5)

Country Link
US (1) US5247339A (de)
EP (1) EP0501005B1 (de)
JP (1) JP3121849B2 (de)
CA (1) CA2050761A1 (de)
DE (1) DE69131844T2 (de)

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US5736410A (en) 1992-09-14 1998-04-07 Sri International Up-converting reporters for biological and other assays using laser excitation techniques
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US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6580504B1 (en) 1999-01-25 2003-06-17 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
US6309886B1 (en) * 1999-06-04 2001-10-30 The Regents Of The University Of California High throughput analysis of samples in flowing liquid
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US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
CA2408939C (en) 2000-05-09 2011-11-08 Xy, Inc. High purity x-chromosome bearing and y-chromosome bearing populations of spermatozoa
US7630063B2 (en) * 2000-08-02 2009-12-08 Honeywell International Inc. Miniaturized cytometer for detecting multiple species in a sample
US6778263B2 (en) * 2000-08-25 2004-08-17 Amnis Corporation Methods of calibrating an imaging system using calibration beads
US6583865B2 (en) 2000-08-25 2003-06-24 Amnis Corporation Alternative detector configuration and mode of operation of a time delay integration particle analyzer
US6875973B2 (en) * 2000-08-25 2005-04-05 Amnis Corporation Auto focus for a flow imaging system
US6608680B2 (en) 2000-08-25 2003-08-19 Amnis Corporation TDI imaging system for kinetic studies
US6934408B2 (en) * 2000-08-25 2005-08-23 Amnis Corporation Method and apparatus for reading reporter labeled beads
WO2002017219A1 (en) 2000-08-25 2002-02-28 Amnis Corporation Measuring the velocity of small moving objects such as cells
US6563583B2 (en) 2000-10-12 2003-05-13 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
AU2002213157A1 (en) 2000-10-12 2002-04-22 Amnis Corporation System and method for high numeric aperture imaging systems
DE10052384B4 (de) * 2000-10-20 2011-02-10 Schwartz, Margit Vorrichtung und Verfahren zur Bestimmung von Partikeleigenschaften und/oder Partikelkonzentrationen in einem fluiden Medium
WO2002043486A1 (en) 2000-11-29 2002-06-06 Xy, Inc. System for in-vitro fertilization with spermatozoa separated into x-chromosome and y-chromosome bearing populations
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
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US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
MX347048B (es) 2003-03-28 2017-04-07 Inguran Llc * Aparato de muestreo digital y métodos para separar partículas.
ES2541121T3 (es) 2003-05-15 2015-07-16 Xy, Llc Clasificación eficiente de células haploides por sistemas de citometría de flujo
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US8150136B2 (en) 2004-03-16 2012-04-03 Amnis Corporation Image based quantitation of molecular translocation
US8953866B2 (en) 2004-03-16 2015-02-10 Amnis Corporation Method for imaging and differential analysis of cells
CA2561661C (en) 2004-03-29 2015-11-24 Monsanto Technology Llc Sperm suspensions for sorting into x or y chromosome-bearing enriched populations
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Also Published As

Publication number Publication date
JP3121849B2 (ja) 2001-01-09
US5247339A (en) 1993-09-21
EP0501005B1 (de) 1999-12-15
CA2050761A1 (en) 1992-08-28
EP0501005A2 (de) 1992-09-02
JPH04270963A (ja) 1992-09-28
EP0501005A3 (en) 1992-12-09
DE69131844T2 (de) 2000-05-18

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee