DE69114323T2 - Charakterisierung von Human-Leukocyt-Antigen. - Google Patents

Charakterisierung von Human-Leukocyt-Antigen.

Info

Publication number
DE69114323T2
DE69114323T2 DE69114323T DE69114323T DE69114323T2 DE 69114323 T2 DE69114323 T2 DE 69114323T2 DE 69114323 T DE69114323 T DE 69114323T DE 69114323 T DE69114323 T DE 69114323T DE 69114323 T2 DE69114323 T2 DE 69114323T2
Authority
DE
Germany
Prior art keywords
amplification
hla
length polymorphism
dna
characterization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69114323T
Other languages
English (en)
Other versions
DE69114323D1 (de
Inventor
Kam Man Hui
Jeffrey Lewis Bidwell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Singapore
Original Assignee
National University of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Singapore filed Critical National University of Singapore
Application granted granted Critical
Publication of DE69114323D1 publication Critical patent/DE69114323D1/de
Publication of DE69114323T2 publication Critical patent/DE69114323T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6858Allele-specific amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
DE69114323T 1990-02-06 1991-02-06 Charakterisierung von Human-Leukocyt-Antigen. Expired - Fee Related DE69114323T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909002625A GB9002625D0 (en) 1990-02-06 1990-02-06 Human leukocyte antigen typing

Publications (2)

Publication Number Publication Date
DE69114323D1 DE69114323D1 (de) 1995-12-14
DE69114323T2 true DE69114323T2 (de) 1996-04-18

Family

ID=10670500

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114323T Expired - Fee Related DE69114323T2 (de) 1990-02-06 1991-02-06 Charakterisierung von Human-Leukocyt-Antigen.

Country Status (7)

Country Link
US (1) US5552275A (de)
EP (1) EP0443748B1 (de)
AT (1) ATE130047T1 (de)
AU (1) AU646655B2 (de)
CA (1) CA2035813A1 (de)
DE (1) DE69114323T2 (de)
GB (1) GB9002625D0 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE164630T1 (de) * 1990-12-06 1998-04-15 Hoffmann La Roche Verfahren und reagenzien für die karakterisierung von hla-drbeta-dns
CA2105585A1 (en) * 1991-03-06 1992-09-07 Pedro Santamaria Dna sequence-based hla typing method
US5976789A (en) * 1991-07-17 1999-11-02 Bio Merieux System of probes enabling HLA-DR typing to be performed, and typing method using said probes
FR2679252B1 (fr) * 1991-07-17 1993-12-10 Bio Merieux Systeme de sondes permettant d'effectuer le typage hla dr, et procede de typage utilisant lesdites sondes.
GB9206567D0 (en) * 1992-03-25 1992-05-06 Univ Bristol Dna analysis
ATE169682T1 (de) * 1993-03-18 1998-08-15 Innogenetics Nv Verfahren zur hla-b typisierung mittels spezifischer primer und probensätzen
WO1995001453A1 (en) * 1993-07-01 1995-01-12 The Board Of Trustees Of The Leland Stanford Junior University A heteroduplex mobility assay for the analysis of nucleic acid sequence diversity
WO1998036091A1 (en) * 1997-02-14 1998-08-20 Medical Research Council Method of determining susceptibility to late-onset alzheimer's disease and dementia with lewy bodies
EP0887423A1 (de) * 1997-06-26 1998-12-30 Biotest Ag Verfahren zur Erkennung von Histokompatibilitätsantigenlocus der Klasse II
EP2186911B1 (de) * 1997-06-26 2015-01-21 BIO-Rad Medical Diagnostics GmbH Verfahren zur Bestimmung des Histocompatibilitätsantigenlokus Klasse II
AU9159298A (en) * 1997-08-06 1999-03-01 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. The use of primers for universal fingerprint analysis
EP0953650A1 (de) 1998-04-20 1999-11-03 Innogenetics N.V. Verfahren für die HLA Typisierung
EP1536021A1 (de) * 2003-11-27 2005-06-01 Consortium National de Recherche en Genomique (CNRG) Methode zur Typisierung von HLA
JP2010506595A (ja) * 2006-10-17 2010-03-04 ライフ テクノロジーズ コーポレーション 対立遺伝子タイピングの方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582788A (en) * 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
DK105582A (da) * 1982-03-11 1983-09-12 Nordisk Insulinlab Fremgangsmaade til bestemmelse af humane hla-d(r) vaevstyper og gensonde til brug ved fremgangsmaaden
CA1254114A (en) * 1984-05-07 1989-05-16 Allied Corporation Displacement polynucleotide assay employing recombination protein and diagnostic kit
ES8706823A1 (es) * 1985-03-28 1987-06-16 Cetus Corp Un procedimiento para detectar la presencia o ausencia de al menos una secuencia especifica de acidos nucleicos en una muestra
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US5310893A (en) * 1986-03-31 1994-05-10 Hoffmann-La Roche Inc. Method for HLA DP typing
US6194561B1 (en) * 1986-03-13 2001-02-27 Roche Molecular Systems, Inc. Characterization and detection of sequences associated with autoimmune diseases
WO1989001050A1 (en) * 1987-07-31 1989-02-09 The Board Of Trustees Of The Leland Stanford Junior University Selective amplification of target polynucleotide sequences
CA1323553C (en) * 1987-11-03 1993-10-26 Timothy George Helentjaris Method and device for improved restriction fragment length polymorphism analysis
WO1989007149A1 (en) * 1988-01-28 1989-08-10 Mayo Foundation For Medical Education And Research Genomic amplification with direct sequencing
JP2897959B2 (ja) * 1988-05-20 1999-05-31 エフ.ホフマン―ラ ロシュ アクチェンゲゼルシャフト 固定化された配列特異的プローブ
WO1990004648A1 (en) * 1988-10-20 1990-05-03 Alexander Alan Morley Method for diagnosis of monoclonality in leukaemia and lymphoma
DE3909354A1 (de) * 1989-03-22 1990-09-27 Hoechst Ag Ferroelektrische fluessigkristallsysteme mit hoher spontaner polarisation und guten orientierungseigenschaften
WO1990013668A1 (en) * 1989-05-05 1990-11-15 Lifecodes Corporation Method for genetic analysis of a nucleic acid sample

Also Published As

Publication number Publication date
ATE130047T1 (de) 1995-11-15
CA2035813A1 (en) 1991-08-07
AU646655B2 (en) 1994-03-03
EP0443748B1 (de) 1995-11-08
EP0443748A2 (de) 1991-08-28
GB9002625D0 (en) 1990-04-04
DE69114323D1 (de) 1995-12-14
EP0443748A3 (en) 1991-09-11
AU7027691A (en) 1991-08-08
US5552275A (en) 1996-09-03

Similar Documents

Publication Publication Date Title
DE69114323D1 (de) Charakterisierung von Human-Leukocyt-Antigen.
US5364759B1 (en) Dna typing with short tandem repeat polymorphisms and indentification of polymorphic short tandem repeats
AU6180190A (en) Fast process for detecting and/or identifying a single base on a nucleic acid sequence and its applications
DK0970240T3 (da) Kunstig fejlparringshydridisering
ATE192503T1 (de) Manipulation von nukleinsäuresequenzen
EP0834576A3 (de) Verfahren die Nukleinsäuren-Patronen auf Oligonukleotid-Matrizzen benutzen
EP1034302A4 (de) De novo oder "universaler" sequenzierungs-array
IL90357A0 (en) Determination of hla-dp allotype and probes therefor
DE69225074T2 (de) Verfahren zur vorbereitung von doppel strangiger rna und seine anwendungen
KR920014936A (ko) 엑소누클레아제로 중개된 사슬 치환에 의한 증폭방법
ES553464A0 (es) Un procedimiento para multiplicar al menos una secuencia especifica de acidos nucleicos
Schneider Basic issues in forensic DNA typing
DE69133629D1 (de) nssystem zur Bestimmung von genetischen Krankheiten
EP0417842A3 (en) Diagnostic and amplification methods overcoming a primer-target mismatch at the primer 3'end
Kuroiwa et al. A method of isolation of mitochondrial nucleoid of Physarum polycephalum and evidence for the presence of a basic protein
DE69518697D1 (de) Nachweis von Treponema Pallidum und Haemophilus Ducreyi
EP0398709A3 (de) Genetische Diagnose von Torsion-Dystonia
EP0382261A3 (de) DNS-Sonden gegen VNTR-Orte
Helminen et al. Amplification of three hypervariable DNA regions by polymerase chain reaction for paternity determinations: comparison with conventional methods and DNA fingerprinting
Steube et al. A simple method using β-globin polymerase chain reaction for the species identification of animal cell lines—a progress report
Hou et al. Typing Y chromosome STR haplotypes using redesigned primers
Langö et al. MATERIALS AND METHODS Amplification DNA from randomly selected blood donors was amplified separately for D1S80, ACTBP2 and HUMTH01 (tab. 2). Additionally DNA from 212 mother-child combinations was amplified for all the systems.
Dobosz et al. Automated Laser Fluorescent Analysis of Amplified Fragment Length Polymorphisms and Short Tandem Repeats
Alekseev et al. Molecular-genetic approaches to the study of the HLA system: New horizons in basic research and applied studies
Hui et al. Human leukocyte antigen typing

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee