DE69113872D1 - Biologisch aktive Reagenzien aus Carboxylgruppenhaltigen Polymerisaten, analytisches Element und Verfahren zur Verwendung. - Google Patents
Biologisch aktive Reagenzien aus Carboxylgruppenhaltigen Polymerisaten, analytisches Element und Verfahren zur Verwendung.Info
- Publication number
- DE69113872D1 DE69113872D1 DE69113872T DE69113872T DE69113872D1 DE 69113872 D1 DE69113872 D1 DE 69113872D1 DE 69113872 T DE69113872 T DE 69113872T DE 69113872 T DE69113872 T DE 69113872T DE 69113872 D1 DE69113872 D1 DE 69113872D1
- Authority
- DE
- Germany
- Prior art keywords
- biologically active
- reagents
- carboxyl groups
- polymers containing
- containing carboxyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000012042 active reagent Substances 0.000 title abstract 2
- 229920000642 polymer Polymers 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- 239000002245 particle Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 229920001577 copolymer Polymers 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/702—Specific hybridization probes for retroviruses
- C12Q1/703—Viruses associated with AIDS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/805—Optical property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2991—Coated
- Y10T428/2998—Coated including synthetic resin or polymer
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/539,774 US5147777A (en) | 1990-06-18 | 1990-06-18 | Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69113872D1 true DE69113872D1 (de) | 1995-11-23 |
DE69113872T2 DE69113872T2 (de) | 1996-06-13 |
Family
ID=24152587
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69113872T Expired - Lifetime DE69113872T2 (de) | 1990-06-18 | 1991-06-10 | Biologisch aktive Reagenzien aus Carboxylgruppenhaltigen Polymerisaten, analytisches Element und Verfahren zur Verwendung. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5147777A (de) |
EP (1) | EP0462644B1 (de) |
JP (1) | JPH0717697B2 (de) |
KR (1) | KR920001202A (de) |
AT (1) | ATE129347T1 (de) |
CA (1) | CA2043089A1 (de) |
DE (1) | DE69113872T2 (de) |
FI (1) | FI912960A (de) |
IE (1) | IE912079A1 (de) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5149737A (en) * | 1990-06-18 | 1992-09-22 | Eastman Kodak Company | Carboxy containing monomers and polymers and latices prepared from same |
DE69128109T2 (de) * | 1990-07-13 | 1998-03-19 | Canon Kk | Nachweisreagens |
US6190864B1 (en) * | 1991-05-08 | 2001-02-20 | Chiron Corporation | HCV genomic sequences for diagnostics and therapeutics |
FR2691546B1 (fr) * | 1992-05-19 | 1997-08-29 | Leroy Olivier | Traceurs particulaires directs, utilisation pour la mesure et le dosage d'anticorps et d'antigene. |
DE4322884A1 (de) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Biologisch aktive Polymere |
US5385844A (en) * | 1993-04-22 | 1995-01-31 | Boehringer Mannheim Corporation | Polymer containing control reagents and polymers useful in control reagents |
US5403707A (en) * | 1993-05-14 | 1995-04-04 | Eastman Kodak Company | Diagnostic compositions, elements, methods and test kits for amplification and detection of retroviral DNA using primers having matched melting temperatures |
US6174668B1 (en) * | 1993-05-14 | 2001-01-16 | Johnson & Johnson Clinical Diagnostics, Inc. | Diagnostic compositions, elements, methods and test kits for amplification and detection of two or more target DNA's using primers having matched melting temperatures |
US6709813B1 (en) | 1993-05-14 | 2004-03-23 | Ortho-Clinical Diagnostics, Inc. | Diagnostic compositions, elements, methods and test kits for amplification and detection of human CMV DNA using primers having matched melting temperatures |
US5643721A (en) * | 1994-02-09 | 1997-07-01 | Abbott Laboratories | Bioreagent immobilization medium |
AU697785B2 (en) | 1994-07-19 | 1998-10-15 | Johnson & Johnson Clinical Diagnostics, Inc. | Analytical element,composition and method using modified apo-horseradish peroxidase |
US5622822A (en) | 1994-09-13 | 1997-04-22 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using polyethyleneimine and an anionic phosphate ester surfactant and amplification of same |
US5705366A (en) | 1994-09-15 | 1998-01-06 | Johnson & Johnson Clinical Diagnostics, Inc. | Coamplification of target nucleic acids using volume exclusion agent in reaction composition, test kit and test device useful therefor |
US5582988A (en) | 1994-09-15 | 1996-12-10 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same |
US5989813A (en) * | 1995-07-13 | 1999-11-23 | Molecular Innovations, Inc. | Detection of amplified nucleic acid sequences using bifunctional haptenization and dyed microparticles |
EP0848819B1 (de) | 1995-09-01 | 2000-04-26 | Ortho-Clinical Diagnostics, Inc. | Analytisches element und verfahren zur bestimmung eines spezifischen bindenden liganden unter verwendung einer vanadin-bromperoxidase als ein signalgenerierendes enzym |
ES2288760T3 (es) | 1996-04-25 | 2008-01-16 | Bioarray Solutions Ltd. | Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies. |
CA2263673A1 (en) * | 1996-08-23 | 1998-02-26 | Abbott Laboratories | Procedure for attaching substances to particles |
US7220596B2 (en) * | 1998-04-15 | 2007-05-22 | Utah State University | Real time detection of antigens |
US6399317B1 (en) | 1998-04-15 | 2002-06-04 | Utah State University | Real time detection of antigens |
PT1206571E (pt) * | 1999-05-04 | 2004-12-31 | Ortho Clinical Diagnostics Inc | Captura rapida e eficaz de adn a partir duma amostra sem recurso a um reagente de lise celular |
CA2387380C (en) * | 1999-10-08 | 2011-08-02 | Robert C. Leif | Conjugated polymer tag complexes |
US7262006B1 (en) | 2000-05-01 | 2007-08-28 | Ortho-Clinical Diagnostics, Inc. | Rapid and efficient capture of DNA from sample without using cell lysing reagent |
US9709559B2 (en) | 2000-06-21 | 2017-07-18 | Bioarray Solutions, Ltd. | Multianalyte molecular analysis using application-specific random particle arrays |
DE60117556T2 (de) | 2000-06-21 | 2006-11-02 | Bioarray Solutions Ltd. | Multianalytische molekularanalyse durch verwendung anwendungsspezifischer zufallspartikelarrays |
US20030045005A1 (en) | 2000-10-17 | 2003-03-06 | Michael Seul | Light-controlled electrokinetic assembly of particles near surfaces |
US20030077598A1 (en) * | 2001-01-04 | 2003-04-24 | Phan Brigitte Chau | Dual bead assays including covalent linkages for improved specificity and related optical analysis discs |
US20020168663A1 (en) * | 2001-02-27 | 2002-11-14 | Phan Brigitte Chau | Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems |
US7262063B2 (en) | 2001-06-21 | 2007-08-28 | Bio Array Solutions, Ltd. | Directed assembly of functional heterostructures |
US20040106109A1 (en) * | 2001-10-02 | 2004-06-03 | Belly Robert T | Detection of ras mutations |
ES2661167T3 (es) | 2001-10-15 | 2018-03-27 | Bioarray Solutions Ltd. | Análisis multiplexado de loci polimórficos mediante consulta simultánea y detección mediada por enzimas |
US7526114B2 (en) | 2002-11-15 | 2009-04-28 | Bioarray Solutions Ltd. | Analysis, secure access to, and transmission of array images |
EP2402089A1 (de) | 2003-07-31 | 2012-01-04 | Handylab, Inc. | Verarbeitung partikelhaltiger Proben |
WO2005029705A2 (en) | 2003-09-18 | 2005-03-31 | Bioarray Solutions, Ltd. | Number coding for identification of subtypes of coded types of solid phase carriers |
AU2004276761B2 (en) | 2003-09-22 | 2009-12-24 | Bioarray Solutions, Ltd. | Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules |
AU2004286252A1 (en) | 2003-10-28 | 2005-05-12 | Bioarray Solutions Ltd. | Optimization of gene expression analysis using immobilized capture probes |
AU2004287069B2 (en) | 2003-10-29 | 2009-07-16 | Bioarray Solutions, Ltd. | Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA |
US8852862B2 (en) | 2004-05-03 | 2014-10-07 | Handylab, Inc. | Method for processing polynucleotide-containing samples |
US7848889B2 (en) | 2004-08-02 | 2010-12-07 | Bioarray Solutions, Ltd. | Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification |
US8486629B2 (en) | 2005-06-01 | 2013-07-16 | Bioarray Solutions, Ltd. | Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation |
EP2001990B1 (de) | 2006-03-24 | 2016-06-29 | Handylab, Inc. | Integriertes system zur verarbeitung von mikrofluidischen proben und verwendungsverfahren |
US11806718B2 (en) | 2006-03-24 | 2023-11-07 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US8883490B2 (en) | 2006-03-24 | 2014-11-11 | Handylab, Inc. | Fluorescence detector for microfluidic diagnostic system |
US7998708B2 (en) | 2006-03-24 | 2011-08-16 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
US10900066B2 (en) | 2006-03-24 | 2021-01-26 | Handylab, Inc. | Microfluidic system for amplifying and detecting polynucleotides in parallel |
WO2009012185A1 (en) | 2007-07-13 | 2009-01-22 | Handylab, Inc. | Polynucleotide capture materials, and methods of using same |
US8105783B2 (en) | 2007-07-13 | 2012-01-31 | Handylab, Inc. | Microfluidic cartridge |
US8287820B2 (en) | 2007-07-13 | 2012-10-16 | Handylab, Inc. | Automated pipetting apparatus having a combined liquid pump and pipette head system |
US8182763B2 (en) | 2007-07-13 | 2012-05-22 | Handylab, Inc. | Rack for sample tubes and reagent holders |
US9186677B2 (en) | 2007-07-13 | 2015-11-17 | Handylab, Inc. | Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples |
BR112013026451B1 (pt) | 2011-04-15 | 2021-02-09 | Becton, Dickinson And Company | sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação |
EP2773892B1 (de) | 2011-11-04 | 2020-10-07 | Handylab, Inc. | Vorrichtung zur vorbereitung von polynukleotidproben |
US9428792B2 (en) | 2013-03-14 | 2016-08-30 | Certirx Corporation | Nucleic acid-based authentication and identification codes |
JP7022741B2 (ja) * | 2016-08-25 | 2022-02-18 | エフ.ホフマン-ラ ロシュ アーゲー | 多機能化ケイ素ナノ粒子、その調製方法、及び電気化学発光に基づく検出方法におけるその使用 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4264766A (en) * | 1877-09-19 | 1981-04-28 | Hoffmann-La Roche Inc. | Immunological diagnostic reagents |
US3616229A (en) * | 1968-09-27 | 1971-10-26 | Monsanto Co | Polymer-enzyme products comprising plurality of enzymes covalently bound to polymer |
US3857931A (en) * | 1971-02-01 | 1974-12-31 | Hoffmann La Roche | Latex polymer reagents for diagnostic tests |
US4138383A (en) * | 1975-11-24 | 1979-02-06 | California Institute Of Technology | Preparation of small bio-compatible microspheres |
US4101549A (en) * | 1976-05-26 | 1978-07-18 | Hoffmann-La Roche Inc. | Aminophenyl esters of 5-carboxyalkyl barbituric acids |
US4140662A (en) * | 1977-03-25 | 1979-02-20 | Ortho Diagnostics, Inc. | Attachment of proteins to inert particles |
DE2721267C2 (de) * | 1977-05-11 | 1985-05-02 | Hans A. Dipl.-Chem. Dr. 8000 München Thoma | Antikörpergel |
CA1101330A (en) * | 1977-09-19 | 1981-05-19 | Ernst A. Fischer | Immunological material bonded to carboxylated latex polymer and process for making it |
JPS56115727A (en) * | 1980-02-19 | 1981-09-11 | Kuraray Co Ltd | Carrier for immobilizing physiologically active substance |
JPS57101761A (en) * | 1980-12-17 | 1982-06-24 | Konishiroku Photo Ind Co Ltd | Analyzing element |
US4766062A (en) * | 1984-05-07 | 1988-08-23 | Allied Corporation | Displacement polynucleotide assay method and polynucleotide complex reagent therefor |
JPS63502875A (ja) * | 1986-03-04 | 1988-10-27 | ケンブリッジ バイオサイエンス コーポレーション | 粒子凝集を用いる核酸検出 |
US4997772A (en) * | 1987-09-18 | 1991-03-05 | Eastman Kodak Company | Water-insoluble particle and immunoreactive reagent, analytical elements and methods of use |
JPH01104621A (ja) * | 1987-09-18 | 1989-04-21 | Eastman Kodak Co | ポリマーラテックス組成物の製造方法 |
US5094962A (en) * | 1988-06-13 | 1992-03-10 | Eastman Kodak Company | Microporous article having a stabilized specific binding reagent, a method for its use and a diagnostic test kit |
US4962154A (en) * | 1988-07-14 | 1990-10-09 | The Dow Chemical Company | Latex-antigen-antibody complexes for immunoassay |
DE3840605A1 (de) * | 1988-12-02 | 1990-06-07 | Behringwerke Ag | Mittel fuer immunchemische tests enthaltend carboxylgruppenhaltige polymere |
-
1990
- 1990-06-18 US US07/539,774 patent/US5147777A/en not_active Expired - Lifetime
-
1991
- 1991-05-23 CA CA002043089A patent/CA2043089A1/en not_active Abandoned
- 1991-06-10 DE DE69113872T patent/DE69113872T2/de not_active Expired - Lifetime
- 1991-06-10 EP EP91201420A patent/EP0462644B1/de not_active Expired - Lifetime
- 1991-06-10 AT AT91201420T patent/ATE129347T1/de not_active IP Right Cessation
- 1991-06-17 KR KR1019910010003A patent/KR920001202A/ko not_active Application Discontinuation
- 1991-06-18 IE IE207991A patent/IE912079A1/en unknown
- 1991-06-18 JP JP3242886A patent/JPH0717697B2/ja not_active Expired - Lifetime
- 1991-06-18 FI FI912960A patent/FI912960A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IE912079A1 (en) | 1991-12-18 |
EP0462644B1 (de) | 1995-10-18 |
FI912960A (fi) | 1991-12-19 |
ATE129347T1 (de) | 1995-11-15 |
DE69113872T2 (de) | 1996-06-13 |
EP0462644A1 (de) | 1991-12-27 |
CA2043089A1 (en) | 1991-12-19 |
KR920001202A (ko) | 1992-01-30 |
JPH0717697B2 (ja) | 1995-03-01 |
JPH04339808A (ja) | 1992-11-26 |
FI912960A0 (fi) | 1991-06-18 |
US5147777A (en) | 1992-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8328 | Change in the person/name/address of the agent |
Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN |