DE69112841T2 - Direktverpressbarer xylit sowie verfahren. - Google Patents

Direktverpressbarer xylit sowie verfahren.

Info

Publication number
DE69112841T2
DE69112841T2 DE69112841T DE69112841T DE69112841T2 DE 69112841 T2 DE69112841 T2 DE 69112841T2 DE 69112841 T DE69112841 T DE 69112841T DE 69112841 T DE69112841 T DE 69112841T DE 69112841 T2 DE69112841 T2 DE 69112841T2
Authority
DE
Germany
Prior art keywords
directly compressible
xylitol
xylite
granulate
metabolic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69112841T
Other languages
English (en)
Other versions
DE69112841D1 (de
Inventor
Philip M Olinger
Auli Karhunen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xyrofin Oy
Original Assignee
Xyrofin Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24510603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69112841(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xyrofin Oy filed Critical Xyrofin Oy
Publication of DE69112841D1 publication Critical patent/DE69112841D1/de
Application granted granted Critical
Publication of DE69112841T2 publication Critical patent/DE69112841T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
DE69112841T 1990-12-12 1991-11-29 Direktverpressbarer xylit sowie verfahren. Expired - Lifetime DE69112841T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/626,495 US5204115A (en) 1990-12-12 1990-12-12 Directly compressible xylitol and method
PCT/FI1991/000362 WO1992010168A1 (en) 1990-12-12 1991-11-29 Directly compressible xylitol and method

Publications (2)

Publication Number Publication Date
DE69112841D1 DE69112841D1 (de) 1995-10-12
DE69112841T2 true DE69112841T2 (de) 1996-04-04

Family

ID=24510603

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69112841T Expired - Lifetime DE69112841T2 (de) 1990-12-12 1991-11-29 Direktverpressbarer xylit sowie verfahren.

Country Status (13)

Country Link
US (1) US5204115A (de)
EP (1) EP0561815B1 (de)
JP (2) JP2753657B2 (de)
AT (1) ATE127337T1 (de)
CA (1) CA2098294C (de)
DE (1) DE69112841T2 (de)
DK (1) DK0561815T3 (de)
EE (1) EE02969B1 (de)
ES (1) ES2079686T3 (de)
FI (1) FI109648B (de)
GR (1) GR3018052T3 (de)
NO (1) NO305424B1 (de)
WO (1) WO1992010168A1 (de)

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CA2128820A1 (en) * 1993-07-27 1995-01-28 Walter G. Gowan, Jr. Rapidly disintegrating pharmaceutical dosage form and process for preparation thereof
ATE253899T1 (de) * 1994-01-31 2003-11-15 Yamanouchi Pharma Co Ltd Intraoral löslicher formpressling und verfahren zu seiner herstellung
US5804165A (en) * 1996-07-24 1998-09-08 Arnold; Michael J. Antiplaque oral composition
US5846568A (en) * 1996-09-19 1998-12-08 Xyrofin Oy Directly compressible lactitol and method
CN1154510C (zh) * 1997-10-15 2004-06-23 默克专利股份有限公司 直压制片助剂的生产方法
FI974385A0 (fi) 1997-12-01 1997-12-01 Xyrofin Oy Anvaendning av xylitol foer bekaempning av jaestinfektion och xylitolpreparat foer denna anvaendning
FI110095B (fi) 1998-05-18 2002-11-29 Xyrofin Oy Ksylitolin kiteyttäminen, kiteinen ksylitolituote ja sen käyttö
NL1009350C2 (nl) * 1998-06-09 1999-12-10 Sara Lee De Nv Zoetstoftablet.
WO2000024380A1 (en) * 1998-10-27 2000-05-04 Fuisz Technologies Ltd. Microparticles containing peg and/or peg glyceryl esters
US7815937B2 (en) * 1998-10-27 2010-10-19 Biovail Laboratories International Srl Quick dissolve compositions and tablets based thereon
US7029717B1 (en) * 1999-04-16 2006-04-18 San-Ei Gen F.F.I., Inc. Sucralose-containing composition and edible products containing the composition
ES2157160B2 (es) * 1999-05-27 2002-12-16 Ind Rodriguez S A Procedimiento de fabricacion de un caramelo refrescante.
DE19943491B4 (de) * 1999-09-10 2010-04-01 Südzucker AG Mannheim/Ochsenfurt Verbesserte Komprimate
FR2802551B1 (fr) * 1999-12-17 2006-08-04 Roquette Freres Dextrose hydrate pulverulent et son procede de preparation
FI117465B (fi) 2000-02-03 2006-10-31 Danisco Sweeteners Oy Menetelmä pureskeltavien ytimien kovapinnoittamiseksi
JP4886107B2 (ja) * 2000-10-13 2012-02-29 サンスター株式会社 歯周病予防用口腔内溶解錠
RU2203042C2 (ru) * 2000-11-28 2003-04-27 Комиссарова Ирина Алексеевна Фармацевтическая композиция и способ ее получения
SE0200539D0 (sv) * 2002-02-25 2002-02-25 Metcon Medicin Ab Granulation process and starch granulate
EP1424319B1 (de) * 2002-10-22 2005-07-06 DHW Deutsche Hydrierwerke GmbH Rodleben Sprühgetrockneter Xylitol und Verfahren zu dessen Herstellung
FR2846520B1 (fr) * 2002-11-06 2006-09-29 Roquette Freres Utilisation de maltodextrines branchees comme liants de granulation
US20040109889A1 (en) * 2002-12-04 2004-06-10 Bunick Frank J. Surface treatment composition for soft substrates
DE10260731B4 (de) * 2002-12-23 2005-04-14 Outokumpu Oyj Verfahren und Anlage zur Wärmebehandlung von eisenoxidhaltigen Feststoffen
DE10260738A1 (de) * 2002-12-23 2004-07-15 Outokumpu Oyj Verfahren und Anlage zur Förderung von feinkörnigen Feststoffen
US6984732B2 (en) * 2003-03-31 2006-01-10 Mcneil-Ppc, Inc. High-intensity sweetener composition and delivery of same
PL1633209T3 (pl) * 2003-06-04 2009-12-31 Nestec Sa Napój wspomagający kontrolowanie masy ciała
US20040258822A1 (en) * 2003-06-16 2004-12-23 Shyhyuan Liao Chilsonated sucralose product
US7282217B1 (en) 2003-08-29 2007-10-16 Kv Pharmaceutical Company Rapidly disintegrable tablets
ES2242523B1 (es) * 2004-02-17 2006-12-01 Enrique Bernat F., S.A. Polvo de xilitol directamente comprimible.
AU2005247060C1 (en) 2004-05-24 2011-03-31 Takeda As Particulate comprising a calcium-containing compound and a sugar alcohol
KR100893847B1 (ko) 2004-06-01 2009-04-17 니코메드 파마 에이에스 칼슘-함유 화합물을 활성 물질로서 함유하는 씹어먹거나흡입 및 삼킬 수 있는 태블릿
WO2006072920A2 (en) * 2005-01-07 2006-07-13 Ranbaxy Laboratories Limited Tablets of stevia extract and process for their preparation
EP1845950A2 (de) 2005-02-03 2007-10-24 Nycomed Pharma AS Schnelles nassbindeverfahren zur herstellung calziumhaltiger verbindungen
DE602006001295D1 (de) 2005-02-03 2008-07-03 Nycomed Pharma As Schmelzgranulation einer zusammensetzung mit einer calziumhaltigen verbindung
US7750146B2 (en) 2005-03-18 2010-07-06 Tate & Lyle Plc Granular sucralose
AU2012201676B2 (en) * 2005-03-30 2012-12-06 Mylan Pharmaceuticals Ulc Combined-step process for pharmaceutical compositions
AU2006228947A1 (en) * 2005-03-30 2006-10-05 Mylan Pharmaceuticals Ulc Combined-step process for pharmaceutical compositions
CN1686089B (zh) * 2005-05-08 2010-08-18 北京健健康康生物技术有限公司 一种可直接压片的木糖醇颗粒及其制备方法
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8906411B2 (en) 2005-12-07 2014-12-09 Takeda Nycomed As Pre-compacted calcium-containing compositions
UA95093C2 (uk) 2005-12-07 2011-07-11 Нікомед Фарма Ас Спосіб одержання кальцієвмісної сполуки
US7807715B2 (en) * 2006-06-09 2010-10-05 Ucb Pharma Gmbh Pharmaceutical compositions comprising fesoterodine
JP4777847B2 (ja) * 2006-08-30 2011-09-21 物産フードサイエンス株式会社 エグ味や収斂味が弱く強い冷涼感をもたらす剤
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
CN101283776A (zh) * 2007-04-11 2008-10-15 欧劳福林精细化工(昆山)有限公司 一种甜味剂颗粒
JP2008263864A (ja) * 2007-04-20 2008-11-06 Hamada Shokuhin Kogyo Kk 易溶性甘味料顆粒
CN101765606A (zh) * 2007-07-27 2010-06-30 卡吉尔公司 多元醇的微粉化
NZ592528A (en) 2008-11-17 2013-05-31 Nycomed Pharma As Improved dissolution stability of calcium carbonate tablets
JP5195623B2 (ja) * 2009-04-30 2013-05-08 ユーハ味覚糖株式会社 打錠菓子
US20110027445A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
US20110027444A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
US20110027446A1 (en) * 2009-07-28 2011-02-03 Heartland Sweeteners, LLC No-calorie sweetener compositions
US20140243514A1 (en) 2010-11-19 2014-08-28 Cargill, Incorporated Method for the enrichment of rebaudioside b and/or rebaudioside d in stevia-derived glycoside compositions using adsorb-desorb chromatography with a macroporous neutral adsorbent resin
CN102429885B (zh) * 2011-12-30 2013-05-08 山东力诺科峰制药有限公司 一种可直接压片的木糖醇及其制备方法
FR3011466A1 (fr) * 2013-10-09 2015-04-10 Roquette Freres Utilisation d'un polyol dans la remineralisation de l'email
US11058633B2 (en) * 2018-05-17 2021-07-13 Fertin Pharma A/S Disintegrating oral tablet suitable for active pharmaceutical ingredients
CN109172533A (zh) * 2018-11-16 2019-01-11 山东福田药业有限公司 一种可直接压片的木糖醇颗粒及其制备方法
CN109512789B (zh) * 2018-11-22 2020-11-20 浙江华康药业股份有限公司 一种可直接压片的高纯度粒状木糖醇及其制备方法
US20210346295A1 (en) * 2020-05-08 2021-11-11 Fertin Pharma A/S Flowpack for oral delivery of active ingredients

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US3042531A (en) * 1959-12-09 1962-07-03 Leslie Salt Company Method of making a compressed tablet
US4013775A (en) * 1968-10-14 1977-03-22 Cpc International Inc. Process for preparing a sugar tablet
DE2912411B2 (de) * 1979-03-29 1981-02-05 August Storck Kg, 4802 Halle Zähplastische, zuckerfreie Süßwarenmasse auf der Grundlage von Sorbit und eines Quellstoffs und Verfahren zu ihrer Herstellung
DE3062775D1 (en) * 1979-11-07 1983-05-19 Tate & Lyle Plc Tablets containing isomaltulose, their use and a method of producing them
US4405647A (en) * 1981-06-15 1983-09-20 Wm. Wrigley Jr. Company Method of compacting chewing gum base
US4569852A (en) * 1983-08-23 1986-02-11 Warner-Lambert Company Maintenance of flavor intensity in pressed tablets
US4753805A (en) * 1984-01-31 1988-06-28 Warner-Lambert Company Tabletted chewing gum composition and method of preparation
US4882154A (en) * 1985-12-20 1989-11-21 Warner Lambert Co. Confectionery delivery system for mineral supplements
US4680189A (en) * 1986-07-07 1987-07-14 Warner-Lambert Company Ingestible, high density, compressed-tablet fiber-composition
SE463541B (sv) * 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
FI81004C (fi) * 1988-02-25 1990-09-10 Suomen Sokeri Oy Binde- och utspaedningsmedel pao basis av xylitol och foerfarande foer dess framstaellning.
JPH0669948B2 (ja) * 1989-07-21 1994-09-07 エスエス製薬株式会社 トローチ剤
US4980169A (en) * 1990-05-03 1990-12-25 Warner-Lambert Company Flavor enhancing and increasing efficacy of cough drops

Also Published As

Publication number Publication date
FI932698A (fi) 1993-06-11
DE69112841D1 (de) 1995-10-12
CA2098294A1 (en) 1992-06-13
NO305424B1 (no) 1999-05-31
WO1992010168A1 (en) 1992-06-25
EP0561815A1 (de) 1993-09-29
NO932118D0 (no) 1993-06-10
FI109648B (fi) 2002-09-30
GR3018052T3 (en) 1996-02-29
EP0561815B1 (de) 1995-09-06
CA2098294C (en) 2000-11-21
JP2753657B2 (ja) 1998-05-20
EE02969B1 (et) 1997-04-15
NO932118L (no) 1993-08-11
US5204115A (en) 1993-04-20
JPH06503080A (ja) 1994-04-07
DK0561815T3 (da) 1995-10-16
ES2079686T3 (es) 1996-01-16
JPH1149666A (ja) 1999-02-23
FI932698A0 (fi) 1993-06-11
ATE127337T1 (de) 1995-09-15

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