US6048729A
(en)
|
1987-05-01 |
2000-04-11 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
FR2646438B1
(fr)
|
1989-03-20 |
2007-11-02 |
Pasteur Institut |
Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration
|
DK0747485T3
(da)
*
|
1989-11-06 |
1999-08-16 |
Cell Genesys Inc |
Fremstilling af proteiner ved anvendelse af homolog rekombination
|
EP0779362B2
(de)
*
|
1989-12-22 |
2012-06-13 |
Laboratoires Serono SA |
DNS-Konstrukten zur Aktivierung und Veränderung der Expression von endogenen Genen
|
US5272071A
(en)
*
|
1989-12-22 |
1993-12-21 |
Applied Research Systems Ars Holding N.V. |
Method for the modification of the expression characteristics of an endogenous gene of a given cell line
|
GB9028062D0
(en)
*
|
1990-12-24 |
1991-02-13 |
Agricultural & Food Res |
Production of transgenic animals
|
WO1992019255A1
(en)
*
|
1991-05-06 |
1992-11-12 |
Cell Genesys, Inc. |
Gene manipulation and expression using genomic elements
|
WO1992021763A1
(en)
*
|
1991-05-31 |
1992-12-10 |
Genentech, Inc. |
Enhancement of expression by gene targeting in endogenous retrovirus-like sequences
|
WO1993004169A1
(en)
*
|
1991-08-20 |
1993-03-04 |
Genpharm International, Inc. |
Gene targeting in animal cells using isogenic dna constructs
|
US6270989B1
(en)
*
|
1991-11-05 |
2001-08-07 |
Transkaryotic Therapies, Inc. |
Protein production and delivery
|
US6692737B1
(en)
|
1991-11-05 |
2004-02-17 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US6054288A
(en)
*
|
1991-11-05 |
2000-04-25 |
Transkaryotic Therapies, Inc. |
In vivo protein production and delivery system for gene therapy
|
US5733761A
(en)
*
|
1991-11-05 |
1998-03-31 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
PT101031B
(pt)
|
1991-11-05 |
2002-07-31 |
Transkaryotic Therapies Inc |
Processo para o fornecimento de proteinas por terapia genetica
|
US6063630A
(en)
|
1991-11-05 |
2000-05-16 |
Transkaryotic Therapies, Inc. |
Targeted introduction of DNA into primary or secondary cells and their use for gene therapy
|
US5641670A
(en)
*
|
1991-11-05 |
1997-06-24 |
Transkaryotic Therapies, Inc. |
Protein production and protein delivery
|
US20020108136A1
(en)
*
|
1997-03-21 |
2002-08-08 |
Sri |
Transgenic animals produced by homologous sequence targeting
|
WO1993024642A1
(en)
*
|
1992-06-04 |
1993-12-09 |
Exemplar Corporation |
Insertion of heterologous dna outside of known chromosomal genes
|
US6670178B1
(en)
|
1992-07-10 |
2003-12-30 |
Transkaryotic Therapies, Inc. |
In Vivo production and delivery of insulinotropin for gene therapy
|
US6531124B1
(en)
|
1992-07-10 |
2003-03-11 |
Transkaryotic Therapies, Inc. |
In vivo production and delivery of insulinotropin for gene therapy
|
US5733753A
(en)
*
|
1992-12-22 |
1998-03-31 |
Novo Nordisk A/S |
Amplification of genomic DNA by site specific integration of a selectable marker construct
|
JP4375759B2
(ja)
|
1993-04-21 |
2009-12-02 |
ザ・ユニバーシティ・コート・オブ・ザ・ユニバーシティ・オブ・エディンバラ |
標的とされた発現特性に従う異種遺伝子の発現
|
US6309853B1
(en)
|
1994-08-17 |
2001-10-30 |
The Rockfeller University |
Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
|
US6001968A
(en)
*
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6124439A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockefeller University |
OB polypeptide antibodies and method of making
|
US6124448A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockfeller University |
Nucleic acid primers and probes for the mammalian OB gene
|
US6048837A
(en)
*
|
1994-08-17 |
2000-04-11 |
The Rockefeller University |
OB polypeptides as modulators of body weight
|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
US5759775A
(en)
|
1994-10-27 |
1998-06-02 |
Genetech, Inc. |
Methods for detecting nucleic acids encoding AL--1 neurotrophic factor
|
US6610296B2
(en)
|
1995-10-26 |
2003-08-26 |
Genentech, Inc. |
Methods of enhancing cognitive function using an AL-1 neurotrophic factor immunoadhesin
|
IL125073A0
(en)
|
1996-01-08 |
1999-01-26 |
Genentech Inc |
Wsx receptor and ligands
|
US7063958B1
(en)
|
1996-01-16 |
2006-06-20 |
The Rockefeller University |
Nucleic acids db, the receptor for leptin
|
US7148004B1
(en)
|
1997-01-16 |
2006-12-12 |
The Rockefeller University |
Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
|
US7084252B1
(en)
|
1996-01-16 |
2006-08-01 |
The Rockefeller University |
DB, the receptor for leptin
|
US7619079B2
(en)
|
1996-02-14 |
2009-11-17 |
The Rockefeller University |
Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
|
US5792210A
(en)
*
|
1996-06-10 |
1998-08-11 |
Environmental Behavior Modification Inc. |
Electrical tongue stimulator and method for addiction treatment
|
CA2263883C
(en)
|
1996-08-29 |
2003-07-08 |
The Regents Of The University Of California |
Kuz, a novel family of metalloproteases
|
US6566089B1
(en)
|
1996-09-04 |
2003-05-20 |
Tularik Inc. |
Cell-based drug screens for regulators of gene expression
|
WO1998011203A1
(en)
*
|
1996-09-13 |
1998-03-19 |
Novo Nordisk Biotech, Inc. |
Cells having dna insertion mutations which produce altered amounts of a polypeptide
|
JPH10117771A
(ja)
*
|
1996-10-23 |
1998-05-12 |
Natl Food Res Inst |
冷凍生地耐性実用パン酵母
|
US5925544A
(en)
*
|
1996-11-18 |
1999-07-20 |
Novo Nordisk A/S |
Method of homologous recombination followed by in vivo selection of DNA amplification
|
US6326204B1
(en)
|
1997-01-17 |
2001-12-04 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
US7148054B2
(en)
*
|
1997-01-17 |
2006-12-12 |
Maxygen, Inc. |
Evolution of whole cells and organisms by recursive sequence recombination
|
IL130635A0
(en)
|
1997-01-17 |
2000-06-01 |
Maxygen Inc |
Evolution of whole cells and organisms by recursive sequence recombination
|
US6372453B1
(en)
|
1997-02-18 |
2002-04-16 |
Genetech, Inc. |
Neurturin receptor
|
US6777196B2
(en)
|
1997-02-18 |
2004-08-17 |
Genentech, Inc. |
Neurturin receptor
|
US6025157A
(en)
*
|
1997-02-18 |
2000-02-15 |
Genentech, Inc. |
Neurturin receptor
|
PT981637E
(pt)
|
1997-03-14 |
2005-09-30 |
Biogen Idec Inc |
Metodo para integrar genes em sitios especificos em celulas de mamifero atraves de recombinacao homologa e vectores para a realizacao do mesmo
|
US5948653A
(en)
*
|
1997-03-21 |
1999-09-07 |
Pati; Sushma |
Sequence alterations using homologous recombination
|
US6172211B1
(en)
|
1997-07-11 |
2001-01-09 |
Boehringer Ingelheim International Gmbh |
Nucleic acid encoding tag7 polypeptide
|
PT986644E
(pt)
|
1997-07-23 |
2007-01-31 |
Roche Diagnostics Gmbh |
Preparação de eritropoietina por activação genética endógena com promotores virais
|
US6548296B1
(en)
|
1997-07-23 |
2003-04-15 |
Roche Diagnostics Gmbh |
Methods for identifying human cell lines useful for endogenous gene activation, isolated human lines identified thereby, and uses thereof
|
ATE354654T1
(de)
*
|
1997-07-23 |
2007-03-15 |
Roche Diagnostics Gmbh |
Identifizierung humaner zellinien zur produktion humaner proteine durch endogene genaktivierung
|
KR100622203B1
(ko)
|
1997-07-23 |
2006-09-07 |
로셰 디아그노스틱스 게엠베하 |
내인성 유전자 활성화에 의해 사람 단백질을 생성시키는 사람 세포주를 확인하는 방법
|
JP4541539B2
(ja)
*
|
1997-07-23 |
2010-09-08 |
ロシュ ダイアグノスティックス ゲーエムベーハー |
内因性遺伝子活性化によるエリスロポエチンの製造
|
US6740503B1
(en)
|
1997-09-26 |
2004-05-25 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
US6897066B1
(en)
|
1997-09-26 |
2005-05-24 |
Athersys, Inc. |
Compositions and methods for non-targeted activation of endogenous genes
|
DE69841723D1
(de)
|
1997-09-26 |
2010-07-29 |
Abt Holding Co |
Expression von endogenen genen durch homologe rekombination eines vektorkonstruktes mit zellulärer dna
|
ZA989497B
(en)
†
|
1997-10-20 |
2000-04-19 |
Roche Diagnostics Gmbh |
Positive-negative selection in homologous recombination.
|
EP2228384A1
(de)
|
1997-11-28 |
2010-09-15 |
Merck Serono Biodevelopment |
Genomsequenz von Chlamydia trachomatis sowie Polypeptide, Fragmente davon und deren Verwendung, insbesondere zur Diagnose, Prävention und Behandlung einer Infektion
|
AU757930B2
(en)
|
1997-12-01 |
2003-03-13 |
Roche Diagnostics Gmbh |
Optimization of cells for endogenous gene activation
|
JPH11243944A
(ja)
*
|
1998-03-04 |
1999-09-14 |
Natl Food Res Inst |
製パン用乾燥耐性実用パン酵母
|
US6294655B1
(en)
|
1998-04-03 |
2001-09-25 |
Hyseq, Inc. |
Anti-interleukin-1 receptor antagonist antibodies and uses thereof
|
US6426191B1
(en)
|
1998-04-03 |
2002-07-30 |
Hyseq, Inc. |
Assays involving an IL-1 receptor antagonist
|
US6337072B1
(en)
|
1998-04-03 |
2002-01-08 |
Hyseq, Inc. |
Interleukin-1 receptor antagonist and recombinant production thereof
|
US6541623B1
(en)
|
1998-04-03 |
2003-04-01 |
Hyseq, Inc. |
Interleukin—1 receptor antagonist and uses thereof
|
US20020061522A1
(en)
|
2000-02-29 |
2002-05-23 |
Glucksmann Maria Alexandra |
1983, 52881, 2398, 45449, 50289, and 52872 novel G protein-coupled receptors and uses therefor
|
CN100365127C
(zh)
|
1998-07-21 |
2008-01-30 |
密理博公司 |
具有遍在染色质开放表达元件(ucoe)的聚核苷酸
|
US6495662B1
(en)
*
|
1998-10-22 |
2002-12-17 |
The General Hospital Corporation |
Bioactive peptides and peptide derivatives of parathyroid hormone (PTH) and parathyroid hormone-related peptide (PTHrP)
|
US6773911B1
(en)
|
1998-11-23 |
2004-08-10 |
Amgen Canada Inc. |
Apoptosis-inducing factor
|
TW570977B
(en)
*
|
1998-12-07 |
2004-01-11 |
Li-Wei Hsu |
An expression system for producing recombinant human erythropoietin, method for purifying secreted human erythropoietin and uses thereof
|
DE19857609A1
(de)
|
1998-12-14 |
2000-06-15 |
Hannelore Ehrenreich |
Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen
|
ES2549440T3
(es)
|
1999-05-18 |
2015-10-28 |
Dyax Corp. |
Bibliotecas de fragmentos de Fab y métodos para su uso
|
US6495360B1
(en)
*
|
1999-05-28 |
2002-12-17 |
Photogen, Inc. |
Method for enhanced protein stabilization and for production of cell lines useful for production of such stabilized proteins
|
US20050129669A1
(en)
*
|
1999-06-21 |
2005-06-16 |
Transkaryotic Therapies, Inc., A Massachusetts Corporation |
DNA construct for effecting homologous recombination and uses thereof
|
US7291714B1
(en)
|
1999-06-30 |
2007-11-06 |
Millennium Pharmaceuticals, Inc. |
Glycoprotein VI and uses thereof
|
WO2001023521A2
(en)
*
|
1999-09-29 |
2001-04-05 |
The General Hospital Corporation |
Polypeptide derivatives of parathyroid hormone (pth)
|
ATE412670T1
(de)
|
1999-09-29 |
2008-11-15 |
Gen Hospital Corp |
Parathyroid hormon (pth) polypeptidderivate
|
AU1647501A
(en)
|
1999-12-10 |
2001-06-18 |
Cytos Biotechnology Ag |
Replicon based activation of endogenous genes
|
US6548274B2
(en)
|
2000-01-13 |
2003-04-15 |
Novozymes Biotech, Inc. |
Methods for producing a polypeptide using a crippled translational initiator sequence
|
EP1714661A3
(de)
|
2000-05-19 |
2012-03-14 |
The Center for Blood Research, INC. |
Verfahren zur Diagnose und Behandlung von hämostatischen Störungen durch Modulation der P-Selectin Aktivität
|
US6656700B2
(en)
|
2000-05-26 |
2003-12-02 |
Amersham Plc |
Isoforms of human pregnancy-associated protein-E
|
US6686188B2
(en)
|
2000-05-26 |
2004-02-03 |
Amersham Plc |
Polynucleotide encoding a human myosin-like polypeptide expressed predominantly in heart and muscle
|
GB0018876D0
(en)
|
2000-08-01 |
2000-09-20 |
Applied Research Systems |
Method of producing polypeptides
|
AU2001284703B2
(en)
*
|
2000-08-03 |
2007-03-22 |
Therapeutic Human Polyclonals Inc. |
Production of humanized antibodies in transgenic animals
|
EP1191036A3
(de)
|
2000-08-25 |
2002-07-03 |
Pfizer Products Inc. |
Methoden und Verbindungen zur Diagnose und Behandlung von Krankheiten, an denen Angiogenese beteiligt ist
|
US7311905B2
(en)
|
2002-02-13 |
2007-12-25 |
Anthrogenesis Corporation |
Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
|
KR100915482B1
(ko)
|
2000-12-06 |
2009-09-03 |
하리리 로버트 제이 |
태반 줄기 세포의 회수 방법
|
DE60144439D1
(de)
|
2000-12-20 |
2011-05-26 |
Hoffmann La Roche |
Konjugate von erythropoietin (epo) mit polyethylenglykol (peg)
|
CA2431964C
(en)
*
|
2000-12-20 |
2013-09-10 |
F. Hoffmann-La Roche Ag |
Conjugates of erythropoietin (pep) with polyethylene glycol (peg)
|
PA8536201A1
(es)
|
2000-12-29 |
2002-08-29 |
Kenneth S Warren Inst Inc |
Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina
|
EP1362095B1
(de)
|
2001-02-14 |
2015-05-27 |
Anthrogenesis Corporation |
Post-partum säugetier-plazenta, deren verwendung und daraus gewonnene stammzellen
|
NZ528035A
(en)
|
2001-02-14 |
2005-07-29 |
Robert J Hariri |
Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells
|
US8981061B2
(en)
|
2001-03-20 |
2015-03-17 |
Novo Nordisk A/S |
Receptor TREM (triggering receptor expressed on myeloid cells) and uses thereof
|
US8231878B2
(en)
|
2001-03-20 |
2012-07-31 |
Cosmo Research & Development S.P.A. |
Receptor trem (triggering receptor expressed on myeloid cells) and uses thereof
|
EP1925671A1
(de)
|
2001-06-06 |
2008-05-28 |
Bioriginal Food & Science Corp. |
Flax-(Linum usitatissimum L.)-Samenspezifische Promotoren
|
US7193134B2
(en)
|
2001-06-06 |
2007-03-20 |
Bioriginal Food & Science Corp. |
Flax (Linum usitatissimum L.) fatty acid desaturase
|
JP4837888B2
(ja)
*
|
2001-07-23 |
2011-12-14 |
ザ ジェネラル ホスピタル コーポレイション |
コンホメーションが拘束された副甲状腺ホルモン(pth)類似体
|
CA2459161A1
(en)
|
2001-08-31 |
2003-03-13 |
The Rockefeller University |
Phosphodiesterase activity and regulation of phosphodiesterase 1b-mediated signaling in brain
|
US20040142325A1
(en)
|
2001-09-14 |
2004-07-22 |
Liat Mintz |
Methods and systems for annotating biomolecular sequences
|
EP1455815A4
(de)
|
2001-12-19 |
2006-11-02 |
Millennium Pharm Inc |
Mitglieder der familie der humanen diacylglycerol-acyltransferase 2 (dgat2) und ihre verwendung
|
AU2003226960B2
(en)
*
|
2002-01-17 |
2007-11-22 |
Lonza Biologics Plc. |
Glutamine-auxothrophic human cells capable of producing proteins and capable of growing in a glutamine-free medium
|
EP2301343A1
(de)
|
2002-02-13 |
2011-03-30 |
Anthrogenesis Corporation |
Embryoartige Stammzellen aus der Post Partum Plazenta von Säugetieren sowie Anwendungszwecke und Behandlungsverfahren, bei denen diese Zellen verwendet werden
|
US7498171B2
(en)
|
2002-04-12 |
2009-03-03 |
Anthrogenesis Corporation |
Modulation of stem and progenitor cell differentiation, assays, and uses thereof
|
AU2003241359A1
(en)
*
|
2002-05-06 |
2003-11-11 |
Functional Genetics, Inc. |
Mammalian genes involed in rapamycin resistance and tumorgenesis: annexin xiii genes
|
WO2003100007A2
(en)
|
2002-05-24 |
2003-12-04 |
Schering-Plough Ltd. |
Eta-1 gene and methods for use
|
US20060099676A1
(en)
*
|
2002-08-15 |
2006-05-11 |
Limin Li |
Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr6 genes
|
WO2004020581A2
(en)
*
|
2002-08-15 |
2004-03-11 |
Functional Genetics, Inc. |
Mammalian genes involved in rapamycin resistance and tumorgenesis: rapr7 genes
|
US7459435B2
(en)
|
2002-08-29 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
AU2003293013A1
(en)
|
2002-11-21 |
2004-06-18 |
University Of Massachusets |
Diagnosing and treating hematopoietic cancers
|
US7459436B2
(en)
|
2002-11-22 |
2008-12-02 |
Hoffmann-La Roche Inc. |
Treatment of disturbances of iron distribution
|
EP2112229A3
(de)
|
2002-11-25 |
2009-12-02 |
Sequenom, Inc. |
Verfahren zum Identifizieren des Brustkrebsrisikos und zugehörige Behandlungen
|
EP1571910A4
(de)
|
2002-11-26 |
2009-10-28 |
Anthrogenesis Corp |
Zytotherapeutika, zytotherapeutischeeinheiten und behandlungsverfahren, bei denen diese verwendet werden
|
CA2513226A1
(en)
*
|
2003-01-13 |
2004-07-29 |
Mahendra S. Rao |
Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products
|
US20050048041A1
(en)
*
|
2003-01-13 |
2005-03-03 |
Rao Mahendra S. |
Persistent expression of candidate molecule in proliferating stem and progenitor cells for delivery of therapeutic products
|
WO2004064785A2
(en)
|
2003-01-14 |
2004-08-05 |
Dana Farber Cancer Institute |
Cancer therapy sensitizer
|
WO2004071462A2
(en)
|
2003-02-12 |
2004-08-26 |
Johns Hopkins University |
Methods and compositions for treatment of viral infections based on tsg101-vps28 interaction
|
JP4334480B2
(ja)
*
|
2003-03-19 |
2009-09-30 |
ザ ジェネラル ホスピタル コーポレイション |
α−ヘリックス安定化剤を用いる高次構造的に制約された副甲状腺ホルモン
|
EP1653985A4
(de)
|
2003-07-17 |
2009-08-05 |
Gen Hospital Corp |
Zwangsform-parathormon (pth)-analoga
|
US7287952B2
(en)
*
|
2003-07-23 |
2007-10-30 |
Lockheed Martin Corporation |
Feeder load automation system and method of use
|
US7888121B2
(en)
|
2003-08-08 |
2011-02-15 |
Sangamo Biosciences, Inc. |
Methods and compositions for targeted cleavage and recombination
|
US11311574B2
(en)
|
2003-08-08 |
2022-04-26 |
Sangamo Therapeutics, Inc. |
Methods and compositions for targeted cleavage and recombination
|
US8409861B2
(en)
|
2003-08-08 |
2013-04-02 |
Sangamo Biosciences, Inc. |
Targeted deletion of cellular DNA sequences
|
EA010650B1
(ru)
|
2003-09-29 |
2008-10-30 |
Уоррен Фармасьютикалз, Инк. |
Защищающие ткань цитокины для лечения и профилактики сепсиса и образования спаек
|
WO2005042581A2
(en)
|
2003-11-01 |
2005-05-12 |
Biovation Ltd. |
Modified anti-cd52 antibody
|
DK1696947T3
(en)
*
|
2003-12-19 |
2014-03-17 |
Hoffmann La Roche |
APPLICATION OF ERYTHROPOIETIN IN THE TREATMENT OF DISORDERS OF THE IRON DISTRIBUTION IN CHRONIC INFLAMMATORY INTESTINAL DISEASES
|
ATE409741T1
(de)
*
|
2004-01-19 |
2008-10-15 |
Nsgene As |
Nervenwachstumsfaktor sezernierende menschliche therapeutische zellen
|
EP1784510A4
(de)
|
2004-08-02 |
2010-08-04 |
Janssen Pharmaceutica Nv |
Irak1c-spleissvariante und deren verwendung
|
US7893197B2
(en)
|
2004-08-25 |
2011-02-22 |
Janssen Pharmaceutica N.V. |
Relaxin-3 chimeric polypeptides and their preparation and use
|
JP2008511678A
(ja)
|
2004-09-02 |
2008-04-17 |
イェール ユニバーシティ |
マイクロrnaによるオンコジーンの調節
|
CA2585098C
(en)
|
2004-10-22 |
2018-12-18 |
Revivicor, Inc. |
Porcine genomic kappa and lambda light chain sequences
|
US7619007B2
(en)
|
2004-11-23 |
2009-11-17 |
Adamas Pharmaceuticals, Inc. |
Method and composition for administering an NMDA receptor antagonist to a subject
|
GB0426146D0
(en)
|
2004-11-29 |
2004-12-29 |
Bioxell Spa |
Therapeutic peptides and method
|
US20090311247A1
(en)
*
|
2005-01-25 |
2009-12-17 |
Apollo Life Sciences Limited |
Molecules and chimeric molecules thereof
|
AR052203A1
(es)
|
2005-02-09 |
2007-03-07 |
Bioriginal Food & Science Corp |
Nuevos miembros de la familia de desaturasa de acido graso omega - 3 y usos de estos
|
BRPI0607017B8
(pt)
|
2005-04-06 |
2021-05-25 |
Adamas Pharmaceuticals Inc |
composição farmacêutica compreendendo memantina e donezepil, e seu uso para o tratamento de condições relacionadas ao snc
|
WO2007002528A1
(en)
|
2005-06-23 |
2007-01-04 |
Yale University |
Anti-aging micrornas
|
ES2452595T3
(es)
|
2005-10-13 |
2014-04-02 |
Anthrogenesis Corporation |
Inmunomodulación usando células madre de la placenta
|
US7767420B2
(en)
|
2005-11-03 |
2010-08-03 |
Momenta Pharmaceuticals, Inc. |
Heparan sulfate glycosaminoglycan lyase and uses thereof
|
US8014957B2
(en)
|
2005-12-15 |
2011-09-06 |
Fred Hutchinson Cancer Research Center |
Genes associated with progression and response in chronic myeloid leukemia and uses thereof
|
PL2471904T3
(pl)
|
2005-12-29 |
2019-08-30 |
Celularity, Inc. |
Populacje komórek macierzystych łożyska
|
US8455250B2
(en)
|
2005-12-29 |
2013-06-04 |
Anthrogenesis Corporation |
Co-culture of placental stem cells and stem cells from a second source
|
DE102006004008A1
(de)
|
2006-01-27 |
2007-08-02 |
Hannelore Prof. Dr. Dr. Ehrenreich |
Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
|
WO2007112005A2
(en)
|
2006-03-24 |
2007-10-04 |
Syntonix Pharmaceuticals, Inc. |
Pc5 as a factor ix propeptide processing enzyme
|
US10522240B2
(en)
|
2006-05-03 |
2019-12-31 |
Population Bio, Inc. |
Evaluating genetic disorders
|
US7702468B2
(en)
|
2006-05-03 |
2010-04-20 |
Population Diagnostics, Inc. |
Evaluating genetic disorders
|
EP2035439A4
(de)
|
2006-06-05 |
2010-01-13 |
Cancer Care Ontario |
Abschätzung des risikos von colorectalkrebs
|
US8143374B2
(en)
*
|
2006-08-04 |
2012-03-27 |
The General Hospital Corporation |
Polypeptide derivatives of parathyroid hormone (PTH)
|
US8765924B2
(en)
|
2006-08-04 |
2014-07-01 |
Prolong Pharmaceuticals, Inc. |
Modified erythropoietin
|
ES2378407T3
(es)
|
2006-09-01 |
2012-04-12 |
Therapeutic Human Polyclonals, Inc. |
Aumento de la expresión de inmunoglobulina humana o humanizada en animales transgénicos no humanos
|
CA2850793A1
(en)
|
2006-10-23 |
2008-05-02 |
Anthrogenesis Corporation |
Methods and compositions for treatment of bone defects with placental cell populations
|
US7745148B2
(en)
|
2006-10-30 |
2010-06-29 |
Functional Genetics, Inc. |
Random homozygous gene perturbation to enhance antibody production
|
AU2008216749B2
(en)
|
2007-02-12 |
2014-03-13 |
Celularity Inc. |
Treatment of inflammatory diseases using placental stem cells
|
AU2008222563A1
(en)
|
2007-03-05 |
2008-09-12 |
Cancer Care Ontario |
Assessment of risk for colorectal cancer
|
EP2977452A3
(de)
|
2007-05-11 |
2016-05-25 |
Thomas Jefferson University |
Verfahren zur behandlung und vorbeugung von neurodegenerativen erkrankungen und störungen
|
CN105748480A
(zh)
|
2007-05-11 |
2016-07-13 |
宾夕法尼亚大学理事会 |
治疗皮肤溃疡的方法
|
GB2451928B
(en)
|
2007-06-21 |
2011-03-16 |
Angelica Therapeutics Inc |
Modified Toxins
|
AR067536A1
(es)
|
2007-07-17 |
2009-10-14 |
Hoffmann La Roche |
Metodo para obtener una eritropoyetina mono-pegilada en una forma sustancialmente homogenea
|
AR067537A1
(es)
|
2007-07-17 |
2009-10-14 |
Hoffmann La Roche |
Purificacion de polipeptidos pegilados
|
WO2009010107A1
(en)
|
2007-07-19 |
2009-01-22 |
Hannelore Ehrenreich |
Use of epo receptor activation or stimulation for the improvement of the edss score in patients with multiple sclerosis
|
CA2694667C
(en)
*
|
2007-08-01 |
2018-10-30 |
The General Hospital Corporation |
Screening methods using g-protein coupled receptors and related compositions
|
US9200253B1
(en)
|
2007-08-06 |
2015-12-01 |
Anthrogenesis Corporation |
Method of producing erythrocytes
|
EP2205625B1
(de)
|
2007-09-24 |
2012-09-12 |
Cornell University |
Immunogene proteine aus der genomabgeleiteten äusseren membran von leptospira und darauf basierende zusammensetzungen und verfahren
|
EP2783692B1
(de)
|
2007-09-28 |
2019-01-02 |
Celularity, Inc. |
Tumorsuppression mit menschlichem Plazentaperfusat und menschlichen natürlichen Killerzellen eines Zwischenproduktes aus der Plazenta
|
US8501449B2
(en)
|
2007-12-04 |
2013-08-06 |
Proteon Therapeutics, Inc. |
Recombinant elastase proteins and methods of manufacturing and use thereof
|
EP2570493B1
(de)
|
2008-01-02 |
2016-08-10 |
Suregene LLC |
Genetische Marker für Geisteskrankheiten
|
EP2581455A3
(de)
|
2008-01-17 |
2013-07-10 |
Suregene LLC |
Genetische Marker von Geisteskrankheiten
|
AU2009222056A1
(en)
*
|
2008-03-01 |
2009-09-11 |
Abraxis Bioscience, Llc |
Treatment, diagnostic, and method for discovering antagonist using SPARC specific miRNAs
|
EP3369827B1
(de)
|
2008-03-12 |
2020-12-23 |
The Rockefeller University |
Verfahren und zusammensetzungen zur translationalen profilierung und molekularen phänotypisierung
|
JP2011519951A
(ja)
*
|
2008-05-07 |
2011-07-14 |
アブラクシス バイオサイエンス リミテッド ライアビリティー カンパニー |
miRNAによる薬物治療の増強
|
MX2011001990A
(es)
|
2008-08-20 |
2011-03-29 |
Anthrogenesis Corp |
Composiciones mejoradas de celulas y metodos para preparar las mismas.
|
US8962247B2
(en)
|
2008-09-16 |
2015-02-24 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
|
US8476013B2
(en)
|
2008-09-16 |
2013-07-02 |
Sequenom, Inc. |
Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
WO2010036943A2
(en)
|
2008-09-25 |
2010-04-01 |
Suregene Llc |
Genetic markers for assessing risk of developing bipolar disorder
|
EP3530672B1
(de)
|
2008-09-26 |
2024-05-01 |
Dana-Farber Cancer Institute, Inc. |
Menschliche anti-pd1-, pd-l1- und pd-l2-antikörper und verwendungen davon
|
WO2010037224A1
(en)
*
|
2008-10-03 |
2010-04-08 |
St. Michael's Hospital |
Method for preventing and treating cardiovascular diseases with brca1
|
US20100120063A1
(en)
*
|
2008-10-10 |
2010-05-13 |
Discoverx Corporation |
GPCR Arrestin Assays
|
EP2348827B1
(de)
|
2008-10-27 |
2015-07-01 |
Revivicor, Inc. |
Immunsupprimierte huftiere
|
ES2723098T3
(es)
|
2008-11-04 |
2019-08-21 |
Janssen Pharmaceutica Nv |
Agonistas del péptido CRHR2 y usos de los mismos
|
KR20110086176A
(ko)
|
2008-11-19 |
2011-07-27 |
안트로제네시스 코포레이션 |
양막 유래 부착성 세포
|
US8492133B2
(en)
|
2009-01-20 |
2013-07-23 |
Ramot At Tel Aviv University, Ltd. |
MIR-21 promoter driven targeted cancer therapy
|
WO2010088522A2
(en)
|
2009-01-30 |
2010-08-05 |
Ab Biosciences, Inc. |
Novel lowered affinity antibodies and uses therefor
|
US8211655B2
(en)
*
|
2009-02-12 |
2012-07-03 |
Discoverx Corporation |
Wild-type receptor assays
|
BR112012010661A2
(pt)
|
2009-11-04 |
2016-11-22 |
Janssen Pharmaceutica Nv |
método para tratar insuficiência cardíaca com peptídeos semelhantes à estressecopina
|
EP2499159B1
(de)
|
2009-11-13 |
2017-01-04 |
Dana-Farber Cancer Institute, Inc. |
Zusammensetzungen, kits und verfahren zur diagnose, prognose, überwachung, behandlung und modulierung von auf transplantationen folgenden lymphoproliferativen erkrankungen und hypoxievermittelten angiogeneseerkrankungen mithilfe von galectin-1
|
EP3037435B1
(de)
|
2009-11-17 |
2019-08-07 |
MUSC Foundation for Research Development |
Humane monoklonale antikörper gegen menschliches nukleolin
|
ES2577017T3
(es)
|
2009-12-22 |
2016-07-12 |
Sequenom, Inc. |
Procedimientos y kits para identificar la aneuploidia
|
ES2646750T3
(es)
|
2010-01-26 |
2017-12-15 |
Anthrogenesis Corporation |
Tratamiento de cánceres relacionados con hueso utilizando células madre placentarias
|
WO2011094593A2
(en)
|
2010-01-28 |
2011-08-04 |
Ab Biosciences, Inc. |
Novel lowered affinity antibodies and methods of marking the same
|
CN103119054B
(zh)
|
2010-03-26 |
2017-01-18 |
达特茅斯大学理事会 |
Vista调节性t细胞介体蛋白、vista结合剂及其用途
|
US10745467B2
(en)
|
2010-03-26 |
2020-08-18 |
The Trustees Of Dartmouth College |
VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
|
US20150231215A1
(en)
|
2012-06-22 |
2015-08-20 |
Randolph J. Noelle |
VISTA Antagonist and Methods of Use
|
SI2556145T1
(sl)
|
2010-04-07 |
2017-01-31 |
Anthrogenesis Corporation |
Angiogeneza z uporabo placentnih matičnih celic
|
WO2011143406A2
(en)
|
2010-05-13 |
2011-11-17 |
The General Hospital Corporation |
Parathyroid hormone analogs and uses thereof
|
NZ605505A
(en)
|
2010-07-13 |
2015-02-27 |
Anthrogenesis Corp |
Methods of generating natural killer cells
|
CN103392182B
(zh)
|
2010-08-02 |
2017-07-04 |
众有生物有限公司 |
用于发现遗传疾病中致病突变的系统和方法
|
JP5735650B2
(ja)
|
2010-09-14 |
2015-06-17 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
Peg化エリスロポエチンを精製するための方法
|
US20120310140A1
(en)
|
2010-12-01 |
2012-12-06 |
Spinal Modulation, Inc. |
Directed delivery of agents to neural anatomy
|
EP2471543A1
(de)
|
2010-12-02 |
2012-07-04 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Toleranzinduktion oder Immunsuppression zur Verhinderung von insbesondere Transplantat-Wirt-Reaktion (GvHD) durch kurzzeitige Vorinkubation von transplantierten Zellsuspensionen, Geweben oder Organen, die mit Liganden zu Zelloberflächenmolekülen beschichtet sind
|
AR093183A1
(es)
|
2010-12-31 |
2015-05-27 |
Anthrogenesis Corp |
Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
|
EP3443968A1
(de)
|
2011-06-01 |
2019-02-20 |
Celularity, Inc. |
Schmerzbehandlung mithilfe von stammzellen aus der plazenta
|
US20140227293A1
(en)
|
2011-06-30 |
2014-08-14 |
Trustees Of Boston University |
Method for controlling tumor growth, angiogenesis and metastasis using immunoglobulin containing and proline rich receptor-1 (igpr-1)
|
CA2844197A1
(en)
|
2011-08-03 |
2013-02-07 |
The Charlotte-Mecklenburg Hospital Authority D/B/A Carolina Healthcare System |
Treatment of fibrosis using microrna-19b
|
US10221454B2
(en)
|
2011-10-10 |
2019-03-05 |
The Hospital For Sick Children |
Methods and compositions for screening and treating developmental disorders
|
DK2773779T3
(da)
|
2011-11-04 |
2020-11-23 |
Population Bio Inc |
Fremgangsmåder og sammensætninger til diagnosticering, prognose og forebyggelse af neurologiske tilstande
|
US10407724B2
(en)
|
2012-02-09 |
2019-09-10 |
The Hospital For Sick Children |
Methods and compositions for screening and treating developmental disorders
|
US9550830B2
(en)
|
2012-02-15 |
2017-01-24 |
Novo Nordisk A/S |
Antibodies that bind and block triggering receptor expressed on myeloid cells-1 (TREM-1)
|
RS57827B1
(sr)
|
2012-02-15 |
2018-12-31 |
Novo Nordisk As |
Antitela koja vezuju protein 1 prepoznavanja peptidoglikana
|
DK2814844T3
(da)
|
2012-02-15 |
2017-11-13 |
Novo Nordisk As |
Antistoffer, der binder og blokerer udløsende receptor udtrykt på myeloide celler-1 (trem-1)
|
EP2820129A1
(de)
|
2012-03-02 |
2015-01-07 |
Sequenom, Inc. |
Verfahren und prozesse zur nichtinvasiven beurteilung genetischer variationen
|
US9494597B2
(en)
|
2012-04-02 |
2016-11-15 |
Ab Biosciences, Inc. |
Human control antibodies and uses therefor
|
DK2839013T3
(da)
*
|
2012-04-18 |
2020-09-14 |
Univ Leland Stanford Junior |
Ikke-disruptiv-gen-targetering
|
US9920361B2
(en)
|
2012-05-21 |
2018-03-20 |
Sequenom, Inc. |
Methods and compositions for analyzing nucleic acid
|
US9890215B2
(en)
|
2012-06-22 |
2018-02-13 |
King's College London |
Vista modulators for diagnosis and treatment of cancer
|
CA2878979C
(en)
|
2012-07-13 |
2021-09-14 |
Sequenom, Inc. |
Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
|
AU2013312211B2
(en)
|
2012-09-07 |
2018-03-29 |
King's College London |
VISTA modulators for diagnosis and treatment of cancer
|
DK2895621T3
(da)
|
2012-09-14 |
2020-11-30 |
Population Bio Inc |
Fremgangsmåder og sammensætning til diagnosticering, prognose og behandling af neurologiske tilstande
|
US10233495B2
(en)
|
2012-09-27 |
2019-03-19 |
The Hospital For Sick Children |
Methods and compositions for screening and treating developmental disorders
|
CN103864913A
(zh)
|
2012-12-18 |
2014-06-18 |
联亚生技开发股份有限公司 |
重组蛋白
|
AU2014215458A1
(en)
|
2013-02-05 |
2015-08-13 |
Anthrogenesis Corporation |
Natural killer cells from placenta
|
US11060145B2
(en)
|
2013-03-13 |
2021-07-13 |
Sequenom, Inc. |
Methods and compositions for identifying presence or absence of hypermethylation or hypomethylation locus
|
WO2014150600A2
(en)
|
2013-03-15 |
2014-09-25 |
Angelica Therapeutics, Inc. |
Modified toxins
|
WO2014138921A1
(en)
|
2013-03-15 |
2014-09-18 |
Apotex Inc. |
Enhanced liquid formulation stability of erythropoietin alpha through purification processing
|
WO2015081290A1
(en)
|
2013-11-27 |
2015-06-04 |
Inis Biotech Llc |
Methods for modulating angiogenesis of cancers refractory to anti-vegf treatment
|
EP3087098B1
(de)
|
2013-12-24 |
2020-04-08 |
Janssen Pharmaceutica NV |
Anti-vista-antikörper und -fragmente
|
US11014987B2
(en)
|
2013-12-24 |
2021-05-25 |
Janssen Pharmaceutics Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
EP3117011B1
(de)
|
2014-03-13 |
2020-05-06 |
Sequenom, Inc. |
Verfahren und prozesse zur nicht-invasiven beurteilung genetischer variationen
|
MX2016011690A
(es)
|
2014-03-21 |
2016-11-07 |
Univ Leland Stanford Junior |
Edicion del genoma sin nucleasas.
|
CN107073109B
(zh)
|
2014-06-11 |
2021-08-06 |
凯西·A·格林 |
Vista激动剂和拮抗剂抑制或增强体液免疫的用途
|
WO2016036403A1
(en)
|
2014-09-05 |
2016-03-10 |
Population Diagnostics Inc. |
Methods and compositions for inhibiting and treating neurological conditions
|
WO2016044271A2
(en)
|
2014-09-15 |
2016-03-24 |
Children's Medical Center Corporation |
Methods and compositions to increase somatic cell nuclear transfer (scnt) efficiency by removing histone h3-lysine trimethylation
|
EP3015475A1
(de)
|
2014-10-31 |
2016-05-04 |
Novartis AG |
Säugetierzellen zur Expression von Cytomegalovirus-Antigenen
|
EP3226900A4
(de)
|
2014-12-05 |
2018-09-19 |
Immunext, Inc. |
Identifizierung von vsig8 als vermeintlicher vista-rezeptor und dessen verwendung zur herstellung von vista/vsig8-modulatoren
|
EP3031822A1
(de)
|
2014-12-08 |
2016-06-15 |
Novartis AG |
Cytomegalovirus-Antigene
|
EP3048114A1
(de)
|
2015-01-22 |
2016-07-27 |
Novartis AG |
Cytomegalovirus-Antigene und Verwendungen davon
|
CA2973878A1
(en)
|
2015-01-22 |
2016-07-28 |
University Of Massachusetts |
Cancer immunotherapy
|
EP3047856A1
(de)
|
2015-01-23 |
2016-07-27 |
Novartis AG |
Cmv-antigene und ihre verwendungen
|
WO2016207717A1
(en)
|
2015-06-24 |
2016-12-29 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments
|
MX2018009800A
(es)
|
2016-02-12 |
2018-11-09 |
Janssen Pharmaceutica Nv |
Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
|
WO2017156032A1
(en)
|
2016-03-07 |
2017-09-14 |
Charlestonpharma, Llc |
Anti-nucleolin antibodies
|
EP3442579A4
(de)
|
2016-04-15 |
2019-12-18 |
Immunext Inc. |
Anti-human-vista-antikörper und verwendung davon
|
KR20220158870A
(ko)
|
2016-07-15 |
2022-12-01 |
에프. 호프만-라 로슈 아게 |
Peg화 에리트로포이에틴을 정제하기 위한 방법
|
WO2018144807A2
(en)
*
|
2017-02-02 |
2018-08-09 |
Massachusetts Institute Of Technology |
Engineered yeast as a method for bioremediation
|
US10240205B2
(en)
|
2017-02-03 |
2019-03-26 |
Population Bio, Inc. |
Methods for assessing risk of developing a viral disease using a genetic test
|
WO2019129876A1
(en)
|
2017-12-29 |
2019-07-04 |
F. Hoffmann-La Roche Ag |
Process for providing pegylated protein composition
|
SG11202005952TA
(en)
|
2017-12-29 |
2020-07-29 |
Hoffmann La Roche |
Process for providing pegylated protein composition
|
WO2019129877A1
(en)
|
2017-12-29 |
2019-07-04 |
F. Hoffmann-La Roche Ag |
Process for providing pegylated protein composition
|
FI3625368T3
(fi)
|
2018-08-08 |
2023-01-13 |
|
Menetelmiä john cunningham -viruksen aiheuttaman progressiivin multifokaalin leukoenkefalopatian kehittymisen riskin arviointiin geneettisellä testauksella
|
US20230201334A1
(en)
|
2019-07-24 |
2023-06-29 |
Glaxosmithkline Biologicals Sa |
Modified human cytomegalovirus proteins
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
WO2023144665A1
(en)
|
2022-01-28 |
2023-08-03 |
Glaxosmithkline Biologicals Sa |
Modified human cytomegalovirus proteins
|