DE69029735D1 - Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse - Google Patents

Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse

Info

Publication number
DE69029735D1
DE69029735D1 DE69029735T DE69029735T DE69029735D1 DE 69029735 D1 DE69029735 D1 DE 69029735D1 DE 69029735 T DE69029735 T DE 69029735T DE 69029735 T DE69029735 T DE 69029735T DE 69029735 D1 DE69029735 D1 DE 69029735D1
Authority
DE
Germany
Prior art keywords
growth
cells
epithelic
promotes
fastening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029735T
Other languages
English (en)
Other versions
DE69029735T2 (de
Inventor
Cary Reich
Jeffrey Forsberg
Harold Levy
Jean Toner-Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Surmodics Inc
Original Assignee
Chiron Vision Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Vision Corp filed Critical Chiron Vision Corp
Publication of DE69029735D1 publication Critical patent/DE69029735D1/de
Application granted granted Critical
Publication of DE69029735T2 publication Critical patent/DE69029735T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/147—Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/34—Macromolecular materials
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/30—Synthetic polymers
    • C12N2533/32—Polylysine, polyornithine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/54—Collagen; Gelatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2537/00—Supports and/or coatings for cell culture characterised by physical or chemical treatment
    • C12N2537/10—Cross-linking
DE69029735T 1989-09-15 1990-09-05 Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse Expired - Fee Related DE69029735T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40805989A 1989-09-15 1989-09-15
PCT/US1990/005028 WO1991003990A1 (en) 1989-09-15 1990-09-05 Method for achieving epithelialization of synthetic lenses

Publications (2)

Publication Number Publication Date
DE69029735D1 true DE69029735D1 (de) 1997-02-27
DE69029735T2 DE69029735T2 (de) 1997-07-31

Family

ID=23614695

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029735T Expired - Fee Related DE69029735T2 (de) 1989-09-15 1990-09-05 Synthetisches material, das die anlagerung, das wachstum und die befestigung von epithelzellen fördert, prosthetische vorrichtung zur subepithelialen implantation sowie behandelte linse

Country Status (9)

Country Link
US (1) US6090995A (de)
EP (1) EP0491860B1 (de)
JP (1) JPH05501971A (de)
KR (1) KR920702975A (de)
AT (1) ATE147613T1 (de)
BR (1) BR9007643A (de)
CA (1) CA2066660C (de)
DE (1) DE69029735T2 (de)
WO (1) WO1991003990A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG81873A1 (en) * 1991-08-16 2001-07-24 Miles A Galin Medicament coated refractive anterior chamber ocular implant
WO1993016176A1 (en) * 1992-02-13 1993-08-19 Bio-Metric Systems, Inc. Immobilization of chemical species in crosslinked matrices
EP0735895B1 (de) * 1993-11-19 2006-01-18 The University Of Sydney Verfahren zur prophylaxe oder kontrolle des katarakts
TW257671B (de) * 1993-11-19 1995-09-21 Ciba Geigy
US6334872B1 (en) 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
DE19505070C2 (de) * 1995-02-15 1997-03-27 Axel Prof Dr Med Haverich Künstliche Gefäßsysteme und Verfahren zu ihrer Herstellung
US20020095218A1 (en) * 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
DE69926017T2 (de) * 1998-04-27 2005-12-22 SurModics, Inc., Eden Prairie Bioaktive Wirkstoffe freisetzende Beschichtungen
AU754437B2 (en) * 1998-06-05 2002-11-14 Organogenesis Inc. Bioengineered tubular graft prostheses
WO1999062427A1 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered vascular graft support prostheses
CA2334364C (en) * 1998-06-05 2011-01-04 Organogenesis Inc. Bioengineered flat sheet graft prostheses
JP4341050B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク． 生体工学により作成した血管移植片補綴
EP1235932A2 (de) 1999-10-08 2002-09-04 Protogene Laboratories, Inc. Verfahren und vorrichtung zur durchführung von hohen zahlen von reaktionen unter benutzung von arrays
BR0000016A (pt) * 2000-01-06 2001-08-14 Ferrara Ophthalmics Ltda Dispositivo para implante intracorneano e processo para tratamento de deformidades da córnea
WO2001087193A1 (en) * 2000-05-16 2001-11-22 Rensselaer Polytechnic Institute Electrically conducting nanocomposite materials for biomedical applications
AU2001291092B2 (en) * 2000-09-18 2007-08-23 Organogenesis Inc. Bioengineered flat sheet graft prosthesis and its use
ATE296593T1 (de) * 2000-11-30 2005-06-15 Aachener Ct Fuer Technologietr Hornhautprothese
JP4043789B2 (ja) * 2001-01-24 2008-02-06 ノバルティス アクチエンゲゼルシャフト 表面を修飾するための方法
US6444318B1 (en) 2001-07-17 2002-09-03 Surmodics, Inc. Self assembling monolayer compositions
US20030018382A1 (en) * 2001-07-17 2003-01-23 Pflugfelder Stephen C. Process for improving vision
US20050064012A1 (en) * 2001-07-17 2005-03-24 Baylor College Of Medicine Process for causing myopic shift in vision
US7348055B2 (en) 2001-12-21 2008-03-25 Surmodics, Inc. Reagent and method for providing coatings on surfaces
US20030216758A1 (en) * 2001-12-28 2003-11-20 Angiotech Pharmaceuticals, Inc. Coated surgical patches
CN100341589C (zh) 2002-05-24 2007-10-10 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
US8313760B2 (en) 2002-05-24 2012-11-20 Angiotech International Ag Compositions and methods for coating medical implants
US7097850B2 (en) * 2002-06-18 2006-08-29 Surmodics, Inc. Bioactive agent release coating and controlled humidity method
MXPA05002669A (es) * 2002-09-13 2005-08-19 Ocular Sciences Inc Dispositivos y metodos para mejorar la vision.
US20040111144A1 (en) * 2002-12-06 2004-06-10 Lawin Laurie R. Barriers for polymeric coatings
US20050233472A1 (en) * 2003-09-19 2005-10-20 Kao H P Spotting high density plate using a banded format
US20050112634A1 (en) * 2003-09-19 2005-05-26 Woudenberg Timothy M. High density sequence detection methods and apparatus
US20050226771A1 (en) * 2003-09-19 2005-10-13 Lehto Dennis A High speed microplate transfer
CA2536242A1 (en) * 2003-11-20 2005-06-09 Angiotech International Ag Implantable sensors and implantable pumps and anti-scarring agents
EP1771131A2 (de) 2004-05-20 2007-04-11 CooperVision Inc. Hornhaut-onlays und wellenfrontaberrationskorrektion zur verbesserung des visus
WO2006002112A1 (en) * 2004-06-18 2006-01-05 Surmodics, Inc. Devices, articles, coatings, and methods for controlled active agent release
AU2005100176A4 (en) * 2005-03-01 2005-04-07 Gym Tv Pty Ltd Garbage bin clip
WO2007012050A2 (en) * 2005-07-20 2007-01-25 Surmodics, Inc. Polymer coated nanofibrillar structures and methods for cell maintenance and differentiation
EP1904118B1 (de) * 2005-07-20 2018-01-17 Surmodics, Inc. Polymerbeschichtungen und verfahren zur zellanhaftung
CN1903144A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工韧带及其制备方法
CN1903143A (zh) * 2005-07-29 2007-01-31 广东冠昊生物科技有限公司 生物型人工血管及其制备方法
CN100482178C (zh) * 2005-08-04 2009-04-29 广东冠昊生物科技有限公司 带生物膜的血管瘤夹
SG10201807556TA (en) * 2005-09-09 2018-10-30 Ottawa Hospital Res Inst Interpenetrating Networks, and Related Methods and Compositions
CN1985778B (zh) * 2005-12-20 2010-10-13 广东冠昊生物科技股份有限公司 生物型人工角膜
CN1986006A (zh) * 2005-12-20 2007-06-27 广州知光生物科技有限公司 生物型神经导管
CN1986007B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物型外科补片
CN1986001B (zh) * 2005-12-20 2011-09-14 广东冠昊生物科技股份有限公司 生物护创膜
US20070218038A1 (en) * 2006-03-17 2007-09-20 Pegasus Biologics, Inc. Stabilized, sterilized collagen scaffolds with active adjuncts attached
US7883520B2 (en) 2006-04-10 2011-02-08 Forsight Labs, Llc Corneal epithelial pocket formation systems, components and methods
WO2007134007A2 (en) * 2006-05-08 2007-11-22 The Ohio State University Research Foundation Aminated materials for assays
CN101332316B (zh) * 2008-07-22 2012-12-26 广东冠昊生物科技股份有限公司 生物型鼻梁植入体
US20100023129A1 (en) * 2008-07-22 2010-01-28 Guo-Feng Xu Jawbone prosthesis and method of manufacture
CN101332314B (zh) * 2008-07-22 2012-11-14 广东冠昊生物科技股份有限公司 生物型关节软骨修补件
WO2008039749A2 (en) * 2006-09-25 2008-04-03 Surmodics, Inc. Multi-layered coatings and methods for controlling elution of active agents
US20090117166A1 (en) * 2007-08-15 2009-05-07 David Myung Sequential coupling of biomolecule layers to polymers
US9943401B2 (en) 2008-04-04 2018-04-17 Eugene de Juan, Jr. Therapeutic device for pain management and vision
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
WO2011050365A1 (en) 2009-10-23 2011-04-28 Forsight Labs, Llc Conformable therapeutic shield for vision and pain
JP2011245053A (ja) 2010-05-27 2011-12-08 Nanyang Technological Univ 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物
EP2535062A1 (de) * 2011-06-13 2012-12-19 Dentsply IH AB Mit Kollagen beschichteter Artikel
US9295531B2 (en) 2011-06-13 2016-03-29 Dentsply International Inc. Collagen coated article
EP3014345A2 (de) 2013-06-26 2016-05-04 Nexisvision, Inc. Kontaktlinsen zur refraktiven korrektur
JP2015077452A (ja) * 2014-12-25 2015-04-23 ナンヤン テクノロジカル ユニヴァーシティー 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物
WO2017221045A1 (en) * 2016-06-24 2017-12-28 Centre National De La Recherche Scientifique (Cnrs) Surface-modified polymeric implantable substrates grafted with a properties-imparting compound using clip chemistry
JP6338715B2 (ja) * 2017-02-06 2018-06-06 ナンヤン テクノロジカル ユニヴァーシティー 眼用及び医療用の重合性組成物及びそれを重合して得られる抗菌性組成物

Family Cites Families (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2714721A (en) * 1953-01-23 1955-08-09 Jr William Stone Artificial corneal implants
US2952023A (en) * 1957-03-19 1960-09-13 Rosen Hyman Corneal fabrication
US3454966A (en) * 1965-02-11 1969-07-15 Hyman Rosen Prosthetic corneal fabrication with heating and cooling means to facilitate attachment to corneal tissue
US3438374A (en) * 1966-02-28 1969-04-15 Us Health Education & Welfare Method of bonding tissue surfaces and controlling hemorrhaging thereof using a tissue adhesive and hemostatic composition
US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US3959078A (en) * 1973-05-18 1976-05-25 Midwest Research Institute Enzyme immobilization with a thermochemical-photochemical bifunctional agent
JPS5338111B2 (de) * 1974-11-14 1978-10-13
SU700125A1 (ru) * 1975-03-17 1979-11-30 Свердловский государственный медицинский институт Способ соединени краев проникающей раны роговицы
SU544429A1 (ru) * 1975-12-08 1977-01-30 Всесоюзный Научно-Исследовательский Институт Глазных Болезней Биологический клей
DE2705234A1 (de) * 1977-02-08 1978-08-17 Hennig Gerhard Keratoprothese
US4126904A (en) * 1977-03-31 1978-11-28 Shepard Dennis D Artificial lens and method of locating on the cornea
US4189546A (en) * 1977-07-25 1980-02-19 Bausch & Lomb Incorporated Polysiloxane shaped article for use in biomedical applications
US4240163A (en) * 1979-01-31 1980-12-23 Galin Miles A Medicament coated intraocular lens
US4223984A (en) * 1979-04-04 1980-09-23 Opticol Corporation Collagen soft contact lens
US4346482A (en) * 1981-01-22 1982-08-31 Tennant Jerald L Living contact lens
US4452235A (en) * 1982-01-04 1984-06-05 Reynolds Alvin E Method for corneal curvature adjustment
JPS58180162A (ja) * 1982-04-19 1983-10-21 株式会社高研 抗血栓性医用材料
US4614517A (en) * 1982-08-04 1986-09-30 La Jolla Cancer Research Foundation Tetrapeptide
US4589881A (en) * 1982-08-04 1986-05-20 La Jolla Cancer Research Foundation Polypeptide
US4722906A (en) * 1982-09-29 1988-02-02 Bio-Metric Systems, Inc. Binding reagents and methods
US5002582A (en) * 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4973493A (en) * 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
DE3241589A1 (de) * 1982-11-10 1984-05-17 Pfaudler-Werke Ag, 6830 Schwetzingen Implantate und verfahren zu deren herstellung
US4656083A (en) * 1983-08-01 1987-04-07 Washington Research Foundation Plasma gas discharge treatment for improving the biocompatibility of biomaterials
JPS60197736A (ja) * 1984-03-21 1985-10-07 Nitto Electric Ind Co Ltd 多孔質薄葉材料の接着方法
JPS60221755A (ja) * 1984-04-18 1985-11-06 Nippon Kayaku Co Ltd 基材表面皮膜の染色法
US4959074A (en) * 1984-08-23 1990-09-25 Gergory Halpern Method of hydrophilic coating of plastics
US4624669A (en) * 1984-09-26 1986-11-25 Surgidev Corporation Corneal inlay with holes
NO166836C (no) * 1985-03-14 1991-09-11 Univ California Fremgangsmaate for behandling av et organtransplantat.
DE3521684A1 (de) * 1985-06-18 1986-12-18 Dr. Müller-Lierheim KG, Biologische Laboratorien, 8033 Planegg Verfahren zur beschichtung von polymeren
US4676790A (en) * 1985-09-25 1987-06-30 Kern Seymour P Method of manufacture and implantation of corneal inlays
US4919659A (en) * 1985-12-16 1990-04-24 The Board Of Regents For The University Of Washington Radio frequency plasma deposited polymers that enhance cell growth
US4662881A (en) * 1986-01-21 1987-05-05 Nordan Lee T Epikeratophakia process
WO1987005038A1 (en) * 1986-02-17 1987-08-27 Commonwealth Scientific And Industrial Research Or Implantable materials
DE3778195D1 (de) * 1986-04-07 1992-05-21 Agency Ind Science Techn Antithrombogenisches material.
US4799931A (en) * 1986-05-14 1989-01-24 Lindstrom Richard L Intracorneal lens
US4772283A (en) * 1986-05-16 1988-09-20 White Thomas C Corneal implant
US4715858A (en) * 1986-07-25 1987-12-29 Lindstrom Richard L Epicorneal lens
US4983181A (en) * 1986-10-16 1991-01-08 Cbs Lens, Collagen hydrogel for promoting epithelial cell growth and artificial lens using the same
US4979959A (en) * 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
DE3637260A1 (de) * 1986-11-03 1988-05-11 Max Planck Gesellschaft Verfahren zur besiedlung von oberflaechen mit endothelzellen
US4782027A (en) * 1987-01-22 1988-11-01 President And Fellows Of Harvard College Protein detection by negative staining
US5094876A (en) * 1987-04-10 1992-03-10 University Of Florida Surface modified surgical instruments, devices, implants, contact lenses and the like
DE3788062D1 (de) * 1987-05-12 1993-12-09 Christian Dr Med Mittermayer Verfahren zur Besiedlung einer Polymeroberfläche mit menschlichen Gefässinnenhautzellen.
US4839464A (en) * 1987-08-25 1989-06-13 Regents Of The University Of Minnesota Polypeptides with fibronectin activity
US5091206A (en) * 1987-10-26 1992-02-25 Baxter Diagnostics Inc. Process for producing magnetically responsive polymer particles and application thereof
AU613442B2 (en) * 1987-11-09 1991-08-01 Chiron Ophthalmics Inc. Implantation of prosthetic devices
CA1335721C (en) * 1987-12-24 1995-05-30 Patrick E. Guire Biomolecule attached to a solid surface by means of a spacer and methods of attaching biomolecules to surfaces
US4976733A (en) * 1988-02-03 1990-12-11 Biomedical Design, Inc. Prevention of prosthesis calcification
JP2772087B2 (ja) * 1988-02-03 1998-07-02 バイオメディカル・デザイン・インコーポレーテッド 補綴材のカルシウム沈着の防止
JPH01300959A (ja) * 1988-05-31 1989-12-05 Canon Inc 表面機能性膜を有する眼内レンズ
EP0425485B1 (de) * 1988-07-22 2000-10-04 SurModics, Inc. Herstellung von polymeren oberflächen
US5080924A (en) * 1989-04-24 1992-01-14 Drexel University Method of making biocompatible, surface modified materials
US5414075A (en) * 1992-11-06 1995-05-09 Bsi Corporation Restrained multifunctional reagent for surface modification

Also Published As

Publication number Publication date
US6090995A (en) 2000-07-18
JPH05501971A (ja) 1993-04-15
KR920702975A (ko) 1992-12-17
EP0491860A1 (de) 1992-07-01
BR9007643A (pt) 1992-08-18
ATE147613T1 (de) 1997-02-15
EP0491860B1 (de) 1997-01-15
WO1991003990A1 (en) 1991-04-04
CA2066660A1 (en) 1991-03-16
EP0491860A4 (en) 1993-06-30
DE69029735T2 (de) 1997-07-31
CA2066660C (en) 2002-07-30

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