DE69023574T2 - Amphotere Zusammensetzungen und Polymerformen von alpha-Hydroxy-Säuren, und ihre therapeutische Anwendung. - Google Patents

Amphotere Zusammensetzungen und Polymerformen von alpha-Hydroxy-Säuren, und ihre therapeutische Anwendung.

Info

Publication number
DE69023574T2
DE69023574T2 DE69023574T DE69023574T DE69023574T2 DE 69023574 T2 DE69023574 T2 DE 69023574T2 DE 69023574 T DE69023574 T DE 69023574T DE 69023574 T DE69023574 T DE 69023574T DE 69023574 T2 DE69023574 T2 DE 69023574T2
Authority
DE
Germany
Prior art keywords
alpha
therapeutic use
hydroxy acids
polymer forms
amphoteric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69023574T
Other languages
English (en)
Other versions
DE69023574D1 (de
Inventor
Eugene J Van Dr Scott
Ruey J Yu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23556084&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69023574(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE69023574D1 publication Critical patent/DE69023574D1/de
Publication of DE69023574T2 publication Critical patent/DE69023574T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/008Preparations for oily skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/191Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/765Polymers containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26Aluminium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/27Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/347Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362Polycarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365Hydroxycarboxylic acids; Ketocarboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • A61K8/375Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • A61K8/416Quaternary ammonium compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43Guanidines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55Phosphorus compounds
    • A61K8/553Phospholipids, e.g. lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/58Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
    • A61K8/585Organosilicon compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/678Tocopherol, i.e. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85Polyesters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00Anti-perspirants or body deodorants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/007Preparations for dry skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/10Washing or bathing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B24GRINDING; POLISHING
    • B24DTOOLS FOR GRINDING, BUFFING OR SHARPENING
    • B24D11/00Constructional features of flexible abrasive materials; Special features in the manufacture of such materials
    • B24D11/02Backings, e.g. foils, webs, mesh fabrics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B24GRINDING; POLISHING
    • B24DTOOLS FOR GRINDING, BUFFING OR SHARPENING
    • B24D18/00Manufacture of grinding tools or other grinding devices, e.g. wheels, not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005Antimicrobial preparations
DE69023574T 1989-08-15 1990-08-10 Amphotere Zusammensetzungen und Polymerformen von alpha-Hydroxy-Säuren, und ihre therapeutische Anwendung. Revoked DE69023574T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07393749 US5091171B2 (en) 1986-12-23 1989-08-15 Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use

Publications (2)

Publication Number Publication Date
DE69023574D1 DE69023574D1 (de) 1995-12-21
DE69023574T2 true DE69023574T2 (de) 1996-03-28

Family

ID=23556084

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69023574T Revoked DE69023574T2 (de) 1989-08-15 1990-08-10 Amphotere Zusammensetzungen und Polymerformen von alpha-Hydroxy-Säuren, und ihre therapeutische Anwendung.

Country Status (10)

Country Link
US (5) US5091171B2 (de)
EP (2) EP0671162A3 (de)
AT (1) ATE130187T1 (de)
AU (1) AU701962B2 (de)
CA (2) CA2337750C (de)
DE (1) DE69023574T2 (de)
DK (1) DK0413528T3 (de)
ES (1) ES2081936T3 (de)
GR (1) GR3018157T3 (de)
MX (1) MX9203653A (de)

Families Citing this family (423)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
US5389677B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of treating wrinkles using glycalic acid
US5702688A (en) * 1986-12-23 1997-12-30 Tristrata Technology, Inc. Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
US5547988B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Alleviating signs of dermatological aging with glycolic acid lactic acid or citric acid
US5942250A (en) * 1986-12-23 1999-08-24 Tristrata Technology, Inc. Compositions and methods for enhancing the topical effects of sunscreen agents
US5686489A (en) * 1986-12-23 1997-11-11 Tristrata Technology, Inc. Alpha hydroxyacid esters for skin aging
US5834510A (en) * 1986-12-23 1998-11-10 Tristrata Technology, Inc. Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging
US5385938B1 (en) * 1986-12-23 1997-07-15 Tristrata Inc Method of using glycolic acid for treating wrinkles
US6051609A (en) * 1997-09-09 2000-04-18 Tristrata Technology, Inc. Additives enhancing the effect of therapeutic agents
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US6384079B1 (en) 1986-12-23 2002-05-07 Tristrata Technology, Incorporated Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging
GB9003201D0 (en) * 1990-02-13 1990-04-11 Unilever Plc Cosmetic composition
JP2564690B2 (ja) 1990-06-14 1996-12-18 三省製薬 株式会社 メラニン生成抑制外用剤
US5254343A (en) * 1991-03-19 1993-10-19 Bristol-Myers Squibb Company Reduction of cutaneous atrophy
AU701232B2 (en) * 1991-04-10 1999-01-21 Eugene J. Van Scott Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging
ATE177629T1 (de) * 1991-04-10 1999-04-15 Yu Ruey J Verwendung von 2-hydroxycarbonsäure oder deren derivaten enthaltende zusammensetzung zur linderung von wechseln nagelveränderungen
FR2678830A1 (fr) * 1991-07-08 1993-01-15 Sederma Sa Nouvelles compositions cosmetiques contenant des acides gras hydroxyles.
DE4128518A1 (de) * 1991-08-28 1993-03-04 Wella Ag Verwendung von dl-valin, dessen estern und/oder salzen zur bekaempfung von kopfschuppen
DE4204321A1 (de) * 1992-02-13 1993-08-19 Beiersdorf Ag Verfahren zur isolierung und reinigung von fettsaeuren und hydroxyfettsaeuren und verwendungen von hydroxyfettsaeuren sowie zubereitungen, die sie enthalten
TW203552B (en) * 1992-02-18 1993-04-11 J Baroody Lloyd Compositions of clindamycin and benzoyl peroxide for acne treatment
IL101492A0 (en) * 1992-04-03 1992-12-30 Shalom Levy Anti-skin rash preparation
US5599546A (en) * 1992-06-16 1997-02-04 Klein; Marvin E. Medicinal facial mask
CA2143629A1 (en) * 1992-09-02 1994-03-17 Michael L. Caswell X-hydroxy saturated fatty acids for the treatment of corns and calluses
DE69231968T2 (de) * 1992-09-11 2001-12-20 Nicholas V Perricone Behandlung eines durch uv-strahlung verursachten erythems
MX9305615A (es) * 1992-09-14 1994-05-31 Walter P Smith Composicion para el acondicionamiento de la piel, su aplicacion y fabricacion.
IT1263831B (it) * 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
DE4307983A1 (de) * 1993-03-13 1994-09-15 Beiersdorf Ag Wirkstoffe und kosmetische und dermatologische Zubereitungen
IL105600A (en) * 1993-05-04 1999-12-31 Allon Blank Pharmaceutical and cosmetic compositions with increased rate of transdermal penetration and antioxidation protection against degradation containing derivatives of thioglycolic and mercaptopropionic acids some such novel compounds and their use
DE4316293C2 (de) * 1993-05-14 1996-05-09 Jobst Krauskopf Verwendung einer Kombination von Anserin/Carnosin und Hypotaurin/Taurin zur Bekämpfung entzündlicher Erkrankungen
US5648394A (en) * 1993-05-27 1997-07-15 Boxall; Brian Alfred Topical composition for inhibiting hair growth
AU688757B2 (en) * 1993-05-27 1998-03-19 Johnson & Johnson Consumer Products, Inc. Retinoid composition
US5646186A (en) * 1994-05-17 1997-07-08 Johnson & Johnson Consumer Products, Inc. Retinoid composition
US6239170B1 (en) 1993-05-28 2001-05-29 Gurpreet S. Ahluwalia Inhibition of hair growth
US6248751B1 (en) 1993-05-28 2001-06-19 Gurpreet S. Ahluwalia Inhibition of hair growth
US6414017B2 (en) 1993-05-28 2002-07-02 The Gillette Company Inhibition of hair growth
US5505948A (en) * 1993-06-01 1996-04-09 Dermatology Home Products, Inc. Home skin peel composition for producing healthy and attractive skin
AU7056894A (en) * 1993-06-01 1994-12-20 Dermatology Home Products, Inc. Skin treatment method utilizing a composition and a pad
FR2706300B1 (fr) * 1993-06-17 1995-09-01 Dior Christian Parfums Utilisation d'un peptide ayant un groupement lysine et un groupement alanine en position terminale pour la préparation d'une composition dépigmentante et composition dépigmentante en comportant application.
FR2707647A1 (fr) * 1993-07-16 1995-01-20 Rocher Yves Biolog Vegetale Dérivés d'alpha-hydroxy acides et composition cosmétique ou pharmaceutique les contenant.
US5561166A (en) * 1993-07-28 1996-10-01 Beiersdorf, Inc. Urea/lactate topical compositions for dry skin
US5407958A (en) * 1993-07-30 1995-04-18 Beauticontrol Cosmetics, Inc. Therapeutic skin composition
US5482710A (en) * 1993-07-30 1996-01-09 Chesebrough-Pond'usa Co., Division Of Conopco, Inc. Cosmetic composition for treatment of pimples and redness
ES2171522T3 (es) * 1993-11-12 2002-09-16 Procter & Gamble Composiciones de desescamacion que contienen acido salicilico y compuestos bipolares.
US5411734A (en) * 1993-11-15 1995-05-02 Elizabeth Arden Company, Division Of Conopco, Inc. Non-irritating α-hydroxy carboxylic acid compositions
US5382432A (en) * 1993-11-15 1995-01-17 Elizabeth Arden Company, Division Of Conopco, Inc. Cosmetic method for treatment of skin
DE4341000A1 (de) * 1993-12-02 1995-06-08 Beiersdorf Ag Verwendung von L-Arginin, L-Ornithin oder L-Citrullin und topischen Zubereitungen mit diesen Stoffen
FR2714825B1 (fr) * 1994-01-11 1996-02-02 Oreal Compositions cosmétiques détergentes à usage capillaire et utilisation de ces dernières.
CA2138244C (fr) * 1994-01-11 2001-07-03 Bernard Beauquey Compositions cosmetiques detergentes a usage capillaire et utilisation
US5425938A (en) * 1994-01-28 1995-06-20 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Polyamino salts of alpha-hydroxyacids, alpha-ketoacids and related compounds
US5393526A (en) * 1994-02-07 1995-02-28 Elizabeth Arden Company, Division Of Conopco, Inc. Cosmetic compositions
US5646131A (en) * 1994-02-22 1997-07-08 The Arab Company For Drug Industries And Medical Applicances (Acdima) Method for solubilizing drugs using cyclodextrins and carboxylic acids
JPH09509933A (ja) * 1994-03-03 1997-10-07 ザ、プロクター、エンド、ギャンブル、カンパニー 抗アクネ組成物
US5474763A (en) * 1994-03-11 1995-12-12 Shander; Douglas Reduction of hair growth
US5468476A (en) * 1994-03-16 1995-11-21 Ahluwalia; Gurpreet S. Reduction of hair growth
US5610199A (en) * 1994-03-22 1997-03-11 Estee Lauder Inc. Solid lipophilic composition and process for its preparation
CA2143515A1 (en) * 1994-03-22 1995-09-23 Prakash Parab Method for enhancing the rate of skin permeation of lactic acid through use of the l-enantiomer
US5420106A (en) * 1994-03-22 1995-05-30 Bristol-Myers Squibb Company Method and composition having enhanced alpha-hydroxy acid skin permeation and retention
US6203803B1 (en) 1994-12-14 2001-03-20 Societe L'oreal S.A. Use of a substance P antagonist in a cosmetic composition, and the composition thus obtained
FR2719474B1 (fr) * 1994-05-05 1996-05-31 Oreal Utilisation d'un antagoniste de substance P dans une composition cosmétique et composition obtenue.
US5441740A (en) * 1994-05-06 1995-08-15 Longevity Network. Ltd. Cosmetic composition containing alpha hydroxyacids, salicyclic acid, and enzyme mixture of bromelain and papain
US5536751A (en) * 1994-05-09 1996-07-16 The United States Of America As Represented By The Secretary Of The Army Pharmaceutical alpha-keto carboxylic acid compositions method of making and use thereof
US5444091A (en) * 1994-05-24 1995-08-22 Dermatology Home Products, Inc. Method of applying alpha hydroxy acids for treating striae distensae
FR2720643B1 (fr) * 1994-06-03 1996-07-26 Clarins Préparation cosmétique destinée à l'amélioration esthétique du revêtement cutané par élimination des cornéocytes.
DE4423450C2 (de) * 1994-07-05 1997-07-24 Beiersdorf Ag Verwendung anorganischer Pigmente in kosmetischen oder dermatologischen Zubereitungen, welche alpha-Hydroxycarbonsäuren und/oder alpha-Ketocarbonsäuren enthalten
WO1996003110A1 (fr) * 1994-07-22 1996-02-08 Coletica Acide hydroxyle lipophile, son utilisation en cosmetique et en pharmacie, et son procede de preparation
IT1271687B (it) * 1994-08-04 1997-06-04 Flamma Spa Sali organici idrosolubili della creatina
US5587396A (en) * 1994-08-26 1996-12-24 Mary Kay Inc. Method of ameliorating cellulite by disrupting the barrier function of the stratum corneum
US5720963A (en) * 1994-08-26 1998-02-24 Mary Kay Inc. Barrier disruption treatments for structurally deteriorated skin
FR2726468B1 (fr) 1994-11-03 1996-12-13 Oreal Utilisation de derive de l'acide salicylique comme stabilisant d'une emulsion huile-dans-eau
CA2204777A1 (en) * 1994-11-15 1996-05-23 Steven Scott Porter Skin care compositions and methods
US5686083A (en) * 1994-12-08 1997-11-11 Schering-Plough Healthcare Products Inc. Compositions for treating corns and calluses
FR2728265A1 (fr) * 1994-12-19 1996-06-21 Oreal Utilisation d'un antagoniste de substance p dans une composition pharmaceutique
FR2728166A1 (fr) * 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
US5690944A (en) * 1994-12-20 1997-11-25 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Cosmetic compositions containing lactate dehydrogenase inhibitors
DE69533714T2 (de) * 1994-12-20 2005-03-24 Unilever N.V. Lactat-dehydrogenase Inhibitoren in kosmetischen Mitteln
US5472698A (en) * 1994-12-20 1995-12-05 Elizabeth Arden Co., Division Of Conopco, Inc. Composition for enhancing lipid production in skin
US7404967B2 (en) 1994-12-21 2008-07-29 Cosmederm, Inc. Topical product formulations containing strontium for reducing skin irritation
FR2728793A1 (fr) * 1994-12-28 1996-07-05 Oreal Utilisation d'un antagoniste d'histamine, d'un antagoniste d'interleukine 1 et/ou d'un antagoniste de tnf-alpha dans une composition cosmetique, pharmaceutique ou dermatologique et composition obtenue
AR003918A1 (es) * 1995-01-11 1998-09-30 Mary Kay Cosmetics Inc Nuevas composiciones cosmeticas que contienen sistemas de liberacion topica para agentes dermatologicamente activos, polares.
WO1996023490A1 (en) * 1995-02-03 1996-08-08 Cosmederm Technologies Formulations and methods for reducing skin irritation
EP0810852A1 (de) * 1995-02-22 1997-12-10 Bausch & Lomb Incorporated Hautpflegemittel
FR2730930B1 (fr) 1995-02-27 1997-04-04 Oreal Utilisation d'inhibiteurs de no-synthase pour diminuer l'effet irritant cutane de produits utilises dans le domaine cosmetique ou pharmaceutique
US5674477A (en) * 1995-02-28 1997-10-07 Ahluwalia; Gurpreet S. Reduction of hair growth
DE69622154T2 (de) * 1995-02-28 2003-02-13 Gillette Co Verwendung von angiogenese-suppressoren zur hemmung des haarwuchses
US5618850A (en) 1995-03-09 1997-04-08 Focal, Inc. Hydroxy-acid cosmetics
TW449485B (en) * 1995-03-31 2001-08-11 Colgate Palmolive Co Skin care products containing anti itching/anti irritant agents
EP0737471A3 (de) * 1995-04-10 2000-12-06 L'oreal Verwendung von Erdalkalimetallsalze als TNF-alpha Inhibitor in einer topischen Zusammensetzung und die so hergestellte Zusammensetzung
FR2732598B1 (fr) 1995-04-10 1997-05-09 Oreal Utilisation de sel de metaux alcalino-terreux pour le traitement des prurits et des dysesthesies oculaires ou palpebraux
US5627187A (en) * 1995-04-12 1997-05-06 Katz; Bruce E. 5-FU for treating actinic kerotoses
FR2732965B1 (fr) * 1995-04-12 1997-07-11 Sochinaz Sa Nouveaux derives de la serine et leur emploi en cosmetique
US5552147A (en) * 1995-04-25 1996-09-03 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Petroleum jelly with alpha hydroxy carboxylic acids
CH688760A5 (de) * 1995-04-28 1998-03-13 Synergen Ag Topisches Praeparat zur Foerderung des Muskelaufbaus.
US5760079A (en) * 1995-05-23 1998-06-02 Dermatology Home Products Inc. Method of applying alpha hydroxy acids for treating striae distensae
DE19518815A1 (de) * 1995-05-23 1996-11-28 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an alpha-Hydroxyfettsäuren
DE19520237A1 (de) * 1995-06-02 1996-12-05 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen, enthaltend Oligomere oder Polymere von alpha-Hydroxycarbonsäuren
DE19520662A1 (de) * 1995-06-07 1996-12-12 Beiersdorf Ag Mittel zur Behandlung von Kopfschuppen und zur Behandlung der Haare
DE19520859A1 (de) * 1995-06-08 1996-12-12 Wella Ag Verwendung einer Betainester und alpha-Hydroxysäuren enthaltenden Zubereitung zur Pflege der Haut sowie neue Hautpflegemittel
US5961999A (en) * 1995-06-08 1999-10-05 Wella Aktiengesellschaft Method of skin care using a skin care preparation containing a betaine ester and an α-hydroxy acid
FR2735688B1 (fr) * 1995-06-26 1997-08-14 Oreal Utilisation en association d'un alpha-hydroxyacide et d'un oxyde de titane pour le blanchiment de la peau
US5691380A (en) * 1995-06-29 1997-11-25 The Procter & Gamble Company Stable n-acetylcysteine compositions and methods for treating human skin therewith
US5948416A (en) * 1995-06-29 1999-09-07 The Procter & Gamble Company Stable topical compositions
FR2737407B1 (fr) * 1995-07-31 1997-09-12 Oreal Utilisation d'acides carboxyliques hydroxyles pour le traitement des matieres keratiniques
US5736537A (en) 1995-09-12 1998-04-07 Estee Lauder, Inc. Dehydroep:androsterone sailcylate useful against skin atrophy
FR2738741B1 (fr) * 1995-09-19 1997-12-05 Oreal Composition pour la teinture des fibres keratiniques, contenant un antagoniste de substance p
US5885593A (en) * 1995-09-28 1999-03-23 The Andrew Jergens Company Skin care composition including cyclodextrin materials and method for treating skin therewith
FR2740341B1 (fr) * 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, d'etain, de zinc, de manganese, d'yttrium, de cobalt, de baryum, de strontium dans une composition pour la peau
FR2740339B1 (fr) * 1995-10-26 1997-12-05 Oreal Utilisation d'au moins un inhibiteur de no-synthase dans le traitement des peaux sensibles
FR2740335B1 (fr) * 1995-10-26 1997-12-19 Oreal Utilisation de sel de lanthanide, de lithium, d'etain, de zinc, de manganese ou d'yttrium comme antagoniste de substance p
US5648389A (en) * 1995-10-27 1997-07-15 Medicis Pharmaceutical, Inc. Compositions for the treatment of dermatological disorders and methods for their use
DE19541968C2 (de) * 1995-11-10 2000-01-13 Beiersdorf Ag Stabile kohlenwasserstofffreie kosmetische oder dermatologische Oleogele und W/O-Emulsionen
US6169110B1 (en) 1995-11-21 2001-01-02 Vivant Pharmaceuticals Rejuvenating the skin using a combination of vitamin A and alphahydroxy acids
WO1997018804A1 (en) * 1995-11-21 1997-05-29 Vivante Pharmaceuticals, Inc. Rejuvenating the skin using a combination of vitamin a and alphahydroxy acids
US5728736A (en) * 1995-11-29 1998-03-17 Shander; Douglas Reduction of hair growth
US5652273A (en) * 1995-11-30 1997-07-29 Henry; James Reduction of hair growth
KR100461085B1 (ko) * 1995-12-20 2005-08-17 주식회사 엘지생활건강 두발화장품조성물
US5759524A (en) * 1996-02-09 1998-06-02 The Procter & Gamble Company Photoprotective compositions
US5683705A (en) * 1996-03-29 1997-11-04 Estee Lauder, Inc. Sulfur-based amides and bis-amides useful against skin disorders
AU2462697A (en) * 1996-04-19 1997-11-12 Hydron Technologies, Inc. Skin tightening formulation and method of treating skin
US5932229A (en) * 1996-04-25 1999-08-03 Avon Products, Inc. Oxa diacids and related compounds for treating skin conditions
US5834513A (en) * 1996-04-25 1998-11-10 Avon Products, Inc. Oxa diacids and related compounds for treating skin conditions
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete
US5847003A (en) * 1996-06-04 1998-12-08 Avon Products, Inc. Oxa acids and related compounds for treating skin conditions
DE19623743A1 (de) * 1996-06-14 1997-12-18 Bayer Ag Herstellungsverfahren für ein stabiles Antischuppenmittel mit Clotrimazol
IL118657A0 (en) * 1996-06-14 1996-10-16 Arad Dorit Inhibitors for picornavirus proteases
US5908867A (en) * 1996-07-18 1999-06-01 Henry; James P. Reduction of hair growth
US5814662A (en) * 1996-11-01 1998-09-29 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin treatment with alpha-hydroxycarboxylic acids of mixed chain length
US5942212A (en) * 1996-11-19 1999-08-24 E-L Management Corp. Self tanning composition containing DHA and α hydroxy acids
US5840752A (en) * 1996-11-21 1998-11-24 Henry; James P. Reduction of hair growth
FR2756489A1 (fr) * 1996-12-02 1998-06-05 Eynard Michele Compositions destinees au traitement des hyperkeratoses
ZA9711121B (en) * 1996-12-13 1998-06-23 Handelman Joseph H Reduction of hair growth.
IT1289754B1 (it) * 1996-12-16 1998-10-16 Professional Dietetics Srl Composizioni a base di aminoacidi
DE19653225A1 (de) * 1996-12-20 1998-06-25 Sueddeutsche Kalkstickstoff Kreatin-pyruvate und Verfahren zu deren Herstellung
DE59700666D1 (de) * 1996-12-20 1999-12-09 Sueddeutsche Kalkstickstoff Kreatin-pyruvate und verfahren zu deren herstellung
US6255295B1 (en) 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6037326A (en) * 1996-12-31 2000-03-14 Styczynski; Peter Reduction of hair growth
JP4578578B2 (ja) * 1997-01-13 2010-11-10 エモリー、ユニバーシティ インフルエンザ感染の治療用化合物及びそれらの組み合わせ
US5776473A (en) 1997-01-17 1998-07-07 Warner-Lambert Company Razor comfort strip with alpha-hydroxy acid additive
FR2758458B1 (fr) * 1997-01-21 2000-01-07 Jean Noel Thorel Produits cosmetiques ou dermo-pharmaceutiques respectant l'ecologie cutanee
CA2281944C (en) * 1997-02-25 2007-05-15 The Regents Of The University Of Michigan Methods and compositions for preventing and treating chronological aging in human skin
DE19714765A1 (de) * 1997-04-10 1998-10-15 Merck Patent Gmbh Verwendung von niedermolekularen, oligomeren Estern von alpha-Hydroxysäuren und/oder aromatischen o-Hydroxysäuren in kosmetischen Formulierungen
US5773473A (en) * 1997-04-15 1998-06-30 Green; Jerold L. Creatine supplement
US5877212A (en) * 1997-04-16 1999-03-02 Yu; Ruey J. Molecular complex and control-release of alpha hydroxyacids
FR2762839B1 (fr) * 1997-04-30 2001-05-11 Oreal Nouveaux derives de l'acide salicylique et leur utilisation dans une composition cosmetique et/ou dermatologique
US5762947A (en) * 1997-05-09 1998-06-09 Elizabeth Arden Co., Division Of Conopco, Inc. Cosmetic skin conditioning compositions containing a salicyloxy α-carboxy acid
USH2043H1 (en) 1997-05-23 2002-08-06 The Procter & Gamble Company Skin care compositions
US5989533A (en) * 1997-07-21 1999-11-23 Revlon Consumer Products Corporation Hair conditioning compositions containing alpha or beta hydroxy acid esters
US5885596A (en) * 1997-07-23 1999-03-23 Bristol-Myers Squibb Company Methods and compositions for fine lines and/or wrinkles
US6197317B1 (en) 1997-08-11 2001-03-06 Marvin E. Klein Composition and method for the treatment of skin
RO118174B1 (ro) * 1997-08-21 2003-03-28 Aventis Pharma Deutschland Gmbh Lac de unghii şi utilizarea acestuia
IN187860B (de) * 1997-08-27 2002-07-06 Revlon Consumer Prod Corp
FR2768053B1 (fr) * 1997-09-09 1999-10-15 Oreal Compositions photoprotectrices comprenant un benzylidene camphre et/ou un dibenzoylmethane et/ou une triazine et un tartrate de dialkyle; utilisations en cosmetique
US5939458A (en) * 1997-09-22 1999-08-17 Henry; James P. Reduction of hair growth
AU8766398A (en) * 1997-10-27 1999-05-17 United States Government Represented By The Secretary Of The Army Novel pharmaceutical alpha-keto carboxylic acid compositions, method of making and use thereof
US6605751B1 (en) * 1997-11-14 2003-08-12 Acrymed Silver-containing compositions, devices and methods for making
US6114337A (en) * 1998-11-27 2000-09-05 Pugliese; Peter T. Zwitteronic-fatty acid compounds having anti-inflammatory properties
US6448251B1 (en) * 1997-11-28 2002-09-10 Peter T. Pugliese Zwitterionic-fatty acid compounds having anti-inflammatory properties
IL122591A0 (en) 1997-12-14 1998-06-15 Arad Dorit Pharmaceutical compositions comprising cystein protease inhibitors
US6159480A (en) * 1997-12-15 2000-12-12 Neostrata Company, Inc. Cosmetic makeup composition
US6191167B1 (en) * 1997-12-29 2001-02-20 Tristrata Technology, Inc. Pharmaceutical compositions containing hydroxycarboxylic acid and/or ketocarboxylic acids and methods of using the same
US5958946A (en) * 1998-01-20 1999-09-28 Styczynski; Peter Modulation of hair growth
US6060471A (en) * 1998-01-21 2000-05-09 Styczynski; Peter Reduction of hair growth
ATE336992T1 (de) * 1998-02-13 2006-09-15 Carol J Buck Verwendung von alkansäuren-enthaltenden zusammensetzungen zur behandlung von nagelpilz- erkrankungen
US6517822B1 (en) 1998-02-13 2003-02-11 Carol J. Buck Formulations and methods for straightening hair
US6231840B1 (en) * 1998-02-13 2001-05-15 Carol J. Buck Compositions and methods for the topical treatment of nail fungi conditions
US6110966A (en) * 1998-02-20 2000-08-29 Medi-Cell Laboratories, Inc. Triple action complex
US6036963A (en) * 1998-02-26 2000-03-14 Chesebrough-Ponds's Usa Co., Division Of Conopco, Inc. Gluconolactones and glucarolactones as anti-irritants in cosmetic compositions
US6703030B2 (en) 1998-06-16 2004-03-09 Marvin E. Klein Amino fruit acid composition and method for the treatment of skin
WO2000000167A1 (en) * 1998-06-26 2000-01-06 Unilever Plc Cosmetic skin care compositions
DE19829709A1 (de) * 1998-07-03 2000-01-05 Beiersdorf Ag Zubereitungen zum Schutze der Kleinkinderhaut vor Dermatitis ammoniacalis
US6149924A (en) * 1998-07-20 2000-11-21 Biomed Research & Technologies, Inc. Composition for enhancing lipid production, barrier function, hydrogen peroxide neutralization, and moisturization of the skin
US6207694B1 (en) * 1998-07-27 2001-03-27 Howard Murad Pharmaceutical compositions and methods for managing scalp conditions
DE19841385A1 (de) * 1998-09-10 2000-03-16 Sueddeutsche Kalkstickstoff Verwendung von Kreatin und/oder Kreatin-derivaten als Feuchthaltemittel in kosmetischen Zubereitungen
US6020006A (en) * 1998-10-27 2000-02-01 The Gillette Company Reduction of hair growth
US7396526B1 (en) 1998-11-12 2008-07-08 Johnson & Johnson Consumer Companies, Inc. Skin care composition
US6808716B2 (en) 1999-01-08 2004-10-26 Ruey J. Yu N-acetylamino acids, related N-acetyl compounds and their topical use
US6159485A (en) 1999-01-08 2000-12-12 Yugenic Limited Partnership N-acetyl aldosamines, n-acetylamino acids and related n-acetyl compounds and their topical use
AUPP839499A0 (en) * 1999-01-29 1999-02-25 Australian National University, The A method for controlling plant pathogens, and agents useful for same
US6121269A (en) * 1999-02-22 2000-09-19 Henry; James P. Reduction of hair growth
US6730308B1 (en) * 1999-03-08 2004-05-04 Allergan, Inc. Tazarotene and alpha hydroxy acid treatment for psoriasis and/or photodamage
US6294182B1 (en) * 1999-03-18 2001-09-25 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Towelette product for minimizing facial fine lines and wrinkles
US6270755B1 (en) * 1999-05-13 2001-08-07 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders
US6290946B1 (en) 1999-05-13 2001-09-18 Geltex Pharmaceuticals, Inc. Anionic polymers as toxin binders and antibacterial agents
EP1800687A3 (de) * 1999-05-13 2009-12-30 Genzyme Corporation Anionische Polymere als Toxinbinder und antibakterielle Wirkstoffe
US6184247B1 (en) * 1999-05-21 2001-02-06 Amway Corporation Method of increasing cell renewal rate
US6242491B1 (en) 1999-06-25 2001-06-05 Rima Kaddurah-Daouk Use of creatine or creatine compounds for skin preservation
US7452545B2 (en) * 2001-11-13 2008-11-18 Yu Ruey J Oligosaccharide aldonic acids and their topical use
US6335023B1 (en) 1999-06-30 2002-01-01 Ruey J. Yu Oligosaccharide aldonic acids and their topical use
FR2795952B1 (fr) 1999-07-08 2003-05-30 Oreal Composition de traitement antipelliculaire des cheveux et du cuir chevelu, a base d'actif antipelliculaire et d'hydroxyacide
US6287582B1 (en) 1999-08-24 2001-09-11 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Towelette product
US6573299B1 (en) * 1999-09-20 2003-06-03 Advanced Medical Instruments Method and compositions for treatment of the aging eye
DE60016867T2 (de) * 1999-10-05 2005-12-22 Kao Corp. Topische Zusammensetzung für die Haut und deren Anwendung
US6689150B1 (en) 1999-10-27 2004-02-10 Atritech, Inc. Filter apparatus for ostium of left atrial appendage
US6572859B1 (en) * 1999-10-29 2003-06-03 Pharmacia Diagnostics Ab Non-anaphylactic forms of grass pollen Phl p 6 allergen and their use
DE60028415T2 (de) * 1999-12-30 2007-06-06 Acrymed, Portland Methode und zusammensetzungen für verbesserte abgabevorrichtungen
US6235737B1 (en) * 2000-01-25 2001-05-22 Peter Styczynski Reduction of hair growth
IT1317863B1 (it) * 2000-02-29 2003-07-15 Vama Farmacosmetica S R L Fabbricazione e utilizzo di amfoglicinati da oli e burri vegetali.
US6808701B2 (en) 2000-03-21 2004-10-26 Johnson & Johnson Consumer Companies, Inc. Conditioning compositions
CA2314494A1 (en) 2000-05-02 2001-11-02 Geltex Pharmaceuticals, Inc. Anionic polymers as species specific antibacterial agents
US6299865B1 (en) 2000-05-02 2001-10-09 Peter Styczynski Reduction of hair growth
US6649176B1 (en) 2000-06-29 2003-11-18 Johnson & Johnson Consumer Companies, Inc. Compositions containing mineral water
US6432424B1 (en) * 2000-06-29 2002-08-13 Johnson & Johnson Consumer Companies, Inc. Cosmetic compositions containing creatine, carnitine, and/or pyruvic acid
US6630175B1 (en) 2000-06-29 2003-10-07 Johnson & Johnson Consumer Companies, Inc. Method of reducing eye irritation
US6372791B1 (en) * 2000-06-29 2002-04-16 Johnson & Johnson Consumer Companies, Inc. Method of promoting skin cell metabolism
DE10032964B4 (de) * 2000-07-06 2017-10-12 Beiersdorf Ag Verwendung von Kreatin in kosmetischen oder dermatologischen Zubereitungen
US6897228B2 (en) * 2000-07-07 2005-05-24 Medicure International Inc. Pyridoxine and pyridoxal analogues: new uses
AU2001281337A1 (en) * 2000-07-24 2002-02-05 Nutrition 21, Inc. Arginine saccharate and use thereof
US6566313B1 (en) 2000-09-15 2003-05-20 Henkel Corporation Shampoo and body wash composition and method of use thereof
US20030095991A1 (en) * 2000-10-02 2003-05-22 Curtis Cole Treatment for skin
US6417226B1 (en) * 2000-12-12 2002-07-09 Nicholas V. Perricone Skin whiteners containing hydroxytetronic acid
JP3843298B2 (ja) * 2001-02-05 2006-11-08 国立大学法人 奈良先端科学技術大学院大学 シトルリンを含有する活性酸素消去剤
FR2820973B1 (fr) 2001-02-19 2003-05-23 Oreal Composition comportant de la vitamine c preparee durant l'application, utilisation d'enzymes pour la formation de vitamine c a usage topique et procede de traitement cosmetique
DE10114561A1 (de) * 2001-03-24 2002-09-26 Wella Ag Verwendung von Mitteln enthaltend Kreatin, Kreatin und/oder deren Derivaten zur Verstärkung und Strukturverbesserung von keratinischen Fasern
EP1377339A4 (de) * 2001-04-04 2006-05-31 Critical Therapeutics Inc Verfahren zur prävention akuter niereninsuffizienz
US6384000B1 (en) 2001-04-18 2002-05-07 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Predominantly synthetic bar comprising hydroxy acid salt and specific types and amounts of filler
FR2823669B1 (fr) * 2001-04-23 2004-03-26 Oreal Procede pour augmenter le seuil de tolerance d'une peau sensible ou intolerante
FR2823670B1 (fr) * 2001-04-23 2004-12-17 Oreal Procede pour diminuer partiellement ou totalement les symptomes associes a la liberation d'histamine dans l'organisme
US20060200174A1 (en) * 2001-05-08 2006-09-07 Stough Dowling B Wart removal method and device
US6585742B2 (en) 2001-05-08 2003-07-01 Dowling B. Stough Wart removal method and device
EP1390383B1 (de) * 2001-05-11 2012-02-29 Isis Pharmaceuticals, Inc. Antisense-permeationsverstärker
SE0101702D0 (sv) 2001-05-15 2001-05-15 Ardenia Investments Ltd Novel potentiating compounds
FR2825273B1 (fr) * 2001-05-29 2006-11-24 Oreal Composition pour le traitement des signes cutanes du vieillissement
WO2002096374A2 (en) * 2001-05-31 2002-12-05 Upsher-Smith Laboratories, Inc. Dermatological compositions and methods comprising alpha-hydroxy acids or derivatives
US7439271B2 (en) 2001-06-27 2008-10-21 The Gillette Company Reduction of hair growth
DE10133195A1 (de) * 2001-07-07 2003-01-16 Beiersdorf Ag Biotin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
DE10133198A1 (de) * 2001-07-07 2003-01-23 Beiersdorf Ag Kreatin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
DE10136076A1 (de) * 2001-07-25 2003-02-13 Beiersdorf Ag Verwendung von Kreatinin und/oder Kreatininderivaten in kosmetischen oder dermatologischen Zubereitungen
DE10136077A1 (de) * 2001-07-25 2003-02-13 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einer Kombination von Kreatinin und/oder Kreatininderivaten mit Kreatin und/oder seinen Derivaten
US6699464B1 (en) 2001-07-30 2004-03-02 Stiefel Laboratories, Inc. Compositions for treatment of hyperpigmentation and methods for making and using such compositions
US6743822B2 (en) 2001-08-10 2004-06-01 The Gillette Company Reduction of hair growth
US7261878B2 (en) 2001-08-10 2007-08-28 The Gillette Company Reduction of hair growth
US7160921B2 (en) 2002-01-29 2007-01-09 The Gillette Company Reduction of hair growth
US8603502B2 (en) 2002-02-04 2013-12-10 L'oreal S.A. Compositions comprising jasmonic acid derivatives and use of these derivatives
FR2835526B1 (fr) 2002-02-04 2006-02-10 Oreal Nouveaux composes, compositions les comprenant et leur utilisation pour favoriser la desquamation
FR2835525B1 (fr) 2002-02-04 2006-02-10 Oreal Nouveaux composes, compositions les comprenant et leur utilisation pour favoriser la desquamation
EP1338269B1 (de) * 2002-02-15 2005-07-27 Goldschmidt GmbH Verwendung von Kreatinin und/oder Kreatinin-Derivaten zur Aufhellung der Haut und Milderung von Pigmentstörungen
IL163846A0 (en) 2002-03-01 2005-12-18 Univ South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
AU2003220691A1 (en) * 2002-04-10 2003-10-27 Van Scott, Eugene J. Urea compositions
AU2003228593B2 (en) * 2002-04-17 2006-07-27 Critical Therapeutics, Inc. Pharmaceutical composition comprising an alpha-ketoalkanoic acid ester or -amine and lactic acid or a lactic acid salt
US7241808B2 (en) * 2002-05-01 2007-07-10 Marvin Klein Composition for treatment of skin and method for stabilizing the composition
JP4473491B2 (ja) * 2002-05-28 2010-06-02 株式会社資生堂 毛穴縮小剤
US20030224027A1 (en) * 2002-05-29 2003-12-04 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Cosmetic compositions with ammonium malonates
US20030224023A1 (en) * 2002-05-29 2003-12-04 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Cosmetic compositions with hydroxy amine salts of malonic acid
US20030228337A1 (en) * 2002-05-29 2003-12-11 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Personal care compositions with hydroxy amine neutralized polymers
US6835385B2 (en) * 2002-06-14 2004-12-28 Carol J. Buck Compositions and methods for softening, thinning and removing hyperkeratotic tissue
US6858215B2 (en) 2002-06-14 2005-02-22 Carol J. Buck Compositions and methods for softening, thinning and removing hyperkeratotic tissue
US6846837B2 (en) 2002-06-21 2005-01-25 Howard I. Maibach Topical administration of basic antifungal compositions to treat fungal infections of the nails
US6921529B2 (en) 2002-07-29 2005-07-26 Joseph C. Maley Treatment modality and method for fungal nail infection
CN1678277B (zh) * 2002-07-29 2010-05-05 艾克里麦德公司 治疗皮肤病的方法和组合物
US20040185016A1 (en) * 2002-07-30 2004-09-23 Popp Karl F Compositions for treatment of hyperpigmentation and methods for making and using such compositions
US20040057974A1 (en) * 2002-08-06 2004-03-25 Naina Sachdev Antiwrinkle composition and age reversal complex
US7338433B2 (en) 2002-08-13 2008-03-04 Allergan, Inc. Remotely adjustable gastric banding method
US6793193B2 (en) * 2002-08-20 2004-09-21 Dart Industries Inc. Adjustable mold for forming shaped food
ES2339009T3 (es) * 2002-08-28 2010-05-14 Allergan, Inc. Dispositivo de banda gastrica resistente a la fatiga.
US7901419B2 (en) * 2002-09-04 2011-03-08 Allergan, Inc. Telemetrically controlled band for regulating functioning of a body organ or duct, and methods of making, implantation and use
US8492366B2 (en) * 2002-10-07 2013-07-23 Societe L'oreal S.A. Enhancedly-solubilized beta-hydroxy acids and higher potency skin peels formulated therefrom
WO2004037305A1 (en) * 2002-10-21 2004-05-06 Allegiance Corporation Coating composition for skin-contacting surface of elastomeric articles and articles containing the same
FR2848832B1 (fr) * 2002-12-19 2005-05-13 Oreal Compositions cosmetiques contenant un tensioactif amphotere et un hydroxyacide et leurs utilisations
US20040185025A1 (en) * 2002-12-19 2004-09-23 Mireille Maubru Cosmetic compositions containing at least one alkylamphohydroxyalkylsulphonate amphoteric surfactant and at least one hydroxy acid, and uses thereof
DE10300782A1 (de) * 2003-01-11 2004-07-22 Beiersdorf Ag Hautpflegeprodukte mit labilen Wirkstoffen in multiplen Emulsionen
DE10301632A1 (de) * 2003-01-17 2004-07-29 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Kreatin, Kreatinin und/oder seinen Derivaten in Kombination mit Sojabohnenkeimextrakten
US20040176453A1 (en) * 2003-03-03 2004-09-09 Arthur Vanmoor Method of treating time-dependent changes in human subjects
US20040175347A1 (en) * 2003-03-04 2004-09-09 The Procter & Gamble Company Regulation of mammalian keratinous tissue using hexamidine compositions
US20040185074A1 (en) * 2003-03-17 2004-09-23 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Odor control in amine salt containing cosmetic compositions
US20040185015A1 (en) * 2003-03-17 2004-09-23 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Sunscreen cosmetic compositions storage stabilized with malonate salts
US20040202689A1 (en) * 2003-03-17 2004-10-14 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Terpenoid fragrance components stabilized with malonic acid salts
US20040185073A1 (en) * 2003-03-17 2004-09-23 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Cosmetic compositions containing salts of malonic acid
FR2852824B1 (fr) * 2003-03-25 2006-07-14 Oreal Utilisation d'un acide hydroxycarboxylique particulier ou ses sels, comme agents de conditionnement des matieres keratiniques
EP1462086A1 (de) * 2003-03-25 2004-09-29 L'oreal Verwendung von einer Carbonsäure und/oder deren Salzen als Konditionierungsmittel für Keratinfasern
US20040220259A1 (en) * 2003-04-04 2004-11-04 Yu Ruey J. Topical treatment of dermatological disorders associated with reactive or dilated blood vessels
EP1466592A1 (de) * 2003-04-07 2004-10-13 Kao Corporation Reinigungszusammensetzungen
DE10316666B4 (de) * 2003-04-10 2015-04-09 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einer Kombination von Kreatinin mit Kreatin und Coenzym Q10
FR2861734B1 (fr) 2003-04-10 2006-04-14 Corneal Ind Reticulation de polysaccharides de faible et forte masse moleculaire; preparation d'hydrogels monophasiques injectables; polysaccharides et hydrogels obtenus
US8637503B2 (en) * 2003-05-16 2014-01-28 Board Of Regents, The University Of Texas System Phenothiazine enantiomers as agents for the prevention of bone loss
US20100285087A1 (en) * 2003-05-16 2010-11-11 The University Of Texas Single phenothiazine enantiomers as agents for the prevention of bone loss
US7776355B2 (en) 2003-07-03 2010-08-17 Medics Pharmaceutical Corporation Delivery system for topical medications
DE10355714A1 (de) * 2003-11-26 2005-06-30 Beiersdorf Ag Wirkstoffkombination aus Kreatin und/oder Kreatinin, Phenoxyethanol und gewünschtenfalls Glycerin
DE10355716A1 (de) * 2003-11-26 2005-06-23 Beiersdorf Ag Kosmetische Zubereitungen mit einem Gehalt Kreatin und/oder Kreatinderivaten und/oder Kreatinin und/oderKreatininderivaten und organischen Verdickern
DE10355715A1 (de) * 2003-11-26 2005-06-16 Beiersdorf Ag Wirkstoffkombinationen Kreatin und/oder Kreatinderivaten und/oder Kreatinin und/oder Kreatininderivaten und einer wirksamen Menge an Retinoiden, insbesondere Retinol bzw. Retinylpalmitat und Zubereitungen, solche Wirkstoffkombinationen enthaltend
DE10359829A1 (de) * 2003-12-12 2005-07-21 Salama, Zoser B., Dr.Rer.Nat. Verwendung von CHP als Inhibitor von Glutathion-S-Transferasen und Kollagen IV
ES2399951T3 (es) 2004-01-23 2013-04-04 Allergan, Inc. Banda gástrica ajustable de una pieza que puede fijarse de forma liberable
DE602005016901D1 (de) * 2004-03-08 2009-11-12 Allergan Medical S A Verschlusssystem für röhrenförmige organe
EP1732635B1 (de) * 2004-03-18 2011-07-27 Allergan, Inc. Vorrichtung zur volumeneinstellung intragastraler ballons
DE102004020627A1 (de) * 2004-03-23 2005-10-13 Beiersdorf Ag Kosmetische und dermatologische Lichtschutzformulierungen
US20070189978A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Compositions and methods for dermally treating musculoskeletal pain
US20070196453A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs
US20080019927A1 (en) * 2004-06-07 2008-01-24 Jie Zhang Compositions and methods for dermally treating neuropathy with minoxidil
US8741333B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for treating dermatitis or psoriasis
US20070196452A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Flux-enabling compositions and methods for dermal delivery of drugs
US20070196325A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for dermally treating infections
US8907153B2 (en) * 2004-06-07 2014-12-09 Nuvo Research Inc. Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
US8741332B2 (en) * 2004-06-07 2014-06-03 Nuvo Research Inc. Compositions and methods for dermally treating neuropathic pain
US20070190124A1 (en) * 2004-06-07 2007-08-16 Jie Zhang Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs
US20070196293A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Compositions and methods for treating photo damaged skin
US20070196457A1 (en) * 2004-06-07 2007-08-23 Jie Zhang Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs
US7854943B2 (en) * 2004-06-24 2010-12-21 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
US7858115B2 (en) * 2004-06-24 2010-12-28 Idexx Laboratories Phospholipid gel compositions for drug delivery and methods of treating conditions using same
CN101010004B (zh) * 2004-07-30 2012-10-03 金伯利-克拉克环球有限公司 抗微生物的装置和组合物
JP5073492B2 (ja) * 2004-07-30 2012-11-14 キンバリー クラーク ワールドワイド インコーポレイテッド 抗菌銀組成物
US8361553B2 (en) 2004-07-30 2013-01-29 Kimberly-Clark Worldwide, Inc. Methods and compositions for metal nanoparticle treated surfaces
US20060040002A1 (en) * 2004-08-17 2006-02-23 Boitano Suzanne M Anti-itch composition
EP1809264B1 (de) * 2004-09-20 2016-04-13 Avent, Inc. Antimikrobielle amorphe zusammensetzungen
US7176172B2 (en) * 2004-10-25 2007-02-13 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Quaternary ammonium polyol salts as anti-aging actives in personal care compositions
US20080103202A1 (en) * 2004-11-08 2008-05-01 Chris Ferguson Method of preparing creatine ester salts and uses thereof.
US7351745B2 (en) * 2004-12-22 2008-04-01 Avon Products, Inc Compositions and methods of their use for improving the condition and appearance of skin
US8251888B2 (en) * 2005-04-13 2012-08-28 Mitchell Steven Roslin Artificial gastric valve
EP1874407B1 (de) * 2005-04-15 2015-09-09 Biomac Privatinstitut für medizinische und Zahnmedizinische Forschung, Entwicklung und Diagnostik GmbH Substanzen und pharmazeutische zusammensetzungen für die hemmung von glyoxalasen und ihre verwendung als antifungale mittel
CA2606255C (fr) * 2005-04-18 2013-10-08 Sc Dicophar Utilisation de la lecithine comme medicament dans le traitement du psoriasis
US20090156680A1 (en) * 2005-05-21 2009-06-18 Alexander Gordon James Deodorants Containing Aminoacid Derivatives
US20060269495A1 (en) * 2005-05-25 2006-11-30 Popp Karl F Alpha hydroxy acid compositions
US20060280711A1 (en) * 2005-06-14 2006-12-14 L'oreal Process for treating marionette lines
TW200744659A (en) * 2005-07-26 2007-12-16 Shiseido Co Ltd Preparation for preventing and ameliorating wrinkle
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
US7709014B2 (en) * 2005-10-17 2010-05-04 Yu Ruey J Hydroxy-oligocarboxylic esters: effects on nerve and use for cutaneous and mucocutaneous organs or sites
US8043206B2 (en) 2006-01-04 2011-10-25 Allergan, Inc. Self-regulating gastric band with pressure data processing
US7798954B2 (en) * 2006-01-04 2010-09-21 Allergan, Inc. Hydraulic gastric band with collapsible reservoir
US7897800B2 (en) * 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
JP5038331B2 (ja) 2006-02-03 2012-10-03 ジェイアール ケム エルエルシー 銅と亜鉛の組成物を用いた老化防止治療
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US20070225360A1 (en) * 2006-03-22 2007-09-27 L'oreal Anti-aging composition containing phloretin
US7754700B2 (en) * 2006-04-24 2010-07-13 Trager Seymour F Composition and methods for alleviating symptoms of neurotoxicity
US20070280972A1 (en) * 2006-04-25 2007-12-06 Zars, Inc. Adhesive solid gel-forming formulations for dermal drug delivery
US8293965B2 (en) * 2006-04-28 2012-10-23 Kimberly-Clark Worldwide, Inc. Antimicrobial site dressings
US7723387B2 (en) * 2006-06-28 2010-05-25 Polymer Surfaces Group, Llc Self-neutralizing acid peel for dermatologic use
US7282225B1 (en) 2006-09-27 2007-10-16 Occular Technologies, Inc. Composition and methods for improving retinal health
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
US8337883B2 (en) 2006-11-03 2012-12-25 Durect Corporation Transdermal delivery systems
BRPI0808907A2 (pt) * 2007-03-20 2014-08-19 Shiseido Co Ltd Agente hidratante, e, composição externa para pele.
US20080293637A1 (en) * 2007-05-23 2008-11-27 Allergan, Inc. Cross-linked collagen and uses thereof
WO2009002913A1 (en) * 2007-06-22 2008-12-31 Avicena Group, Inc. Use of creatine compounds to treat dermatitis
FR2918876B1 (fr) * 2007-07-16 2012-10-05 Oreal Utilisation de lumiere verte pour activer la l-amino acide oxydase
US20110077737A1 (en) * 2007-07-30 2011-03-31 Allergan, Inc. Tunably Crosslinked Polysaccharide Compositions
US8318695B2 (en) * 2007-07-30 2012-11-27 Allergan, Inc. Tunably crosslinked polysaccharide compositions
GB0715141D0 (en) * 2007-08-03 2007-09-12 York Pharma Plc Improving skin barrier function
EP2067467A3 (de) 2007-09-14 2012-12-12 L'Oréal Zusammensetzungen und Verfahren zur Behandlung von Keratinsubstraten
US8697044B2 (en) 2007-10-09 2014-04-15 Allergan, Inc. Crossed-linked hyaluronic acid and collagen and uses thereof
WO2009065116A1 (en) 2007-11-16 2009-05-22 Aspect Pharmaceuticals Llc Compositions and methods for treating purpura
US8394784B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having multi-stage bioactive agent delivery
US8394782B2 (en) * 2007-11-30 2013-03-12 Allergan, Inc. Polysaccharide gel formulation having increased longevity
US20090143348A1 (en) * 2007-11-30 2009-06-04 Ahmet Tezel Polysaccharide gel compositions and methods for sustained delivery of drugs
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
US20090285866A1 (en) * 2008-05-13 2009-11-19 Afriat Isabelle R Self-healing polymer compositions
US8603531B2 (en) 2008-06-02 2013-12-10 Cedars-Sinai Medical Center Nanometer-sized prodrugs of NSAIDs
CN102119023B (zh) 2008-07-03 2014-04-09 弗吉尼亚大学专利基金会 阿帕地松单位剂量
EP2143421A1 (de) 2008-07-07 2010-01-13 Almirall Hermal GmbH Zusammensetzung zur topischen Behandlung von Strahlenkeratose
US8357795B2 (en) 2008-08-04 2013-01-22 Allergan, Inc. Hyaluronic acid-based gels including lidocaine
JP2010065022A (ja) * 2008-08-12 2010-03-25 Kao Corp 毛髪処理用組成物
EP2324064B1 (de) 2008-09-02 2017-11-08 Tautona Group LP Stränge aus hyaluronsäure und/oder derivaten daraus, herstellungsverfahren und verwendung
US8317677B2 (en) * 2008-10-06 2012-11-27 Allergan, Inc. Mechanical gastric band with cushions
US20100305397A1 (en) * 2008-10-06 2010-12-02 Allergan Medical Sarl Hydraulic-mechanical gastric band
ES2336995B1 (es) * 2008-10-13 2011-02-09 Lipotec, S.A. Composicion cosmetica o dermofarmaceutica para el cuidado de la piel,cuero cabelludo y uñas.
US20100185049A1 (en) * 2008-10-22 2010-07-22 Allergan, Inc. Dome and screw valves for remotely adjustable gastric banding systems
JP5638534B2 (ja) * 2008-11-24 2014-12-10 キンバリー クラーク ワールドワイド インコーポレイテッド 抗菌積層構造体
US20140105822A1 (en) * 2008-11-24 2014-04-17 Cedars-Sinai Medical Center Nanospheres comprising tocopherol, an amphiphilic spacer and a therapeutic or imaging agent
CA2750636C (en) 2009-01-23 2017-07-25 Jr Chem, Llc Rosacea treatments and kits for performing them
EP2228050A1 (de) * 2009-03-09 2010-09-15 Marcel Cohen Verwendung von Gamma-Aminobuttersäure als Depigmentierungssubstanz
US20100260695A1 (en) * 2009-04-09 2010-10-14 Mary Kay Inc. Combination of plant extracts to improve skin tone
US20100280310A1 (en) * 2009-05-01 2010-11-04 Allergan, Inc. Laparoscopic Gastric Band With Active Agents
US20110184229A1 (en) * 2009-05-01 2011-07-28 Allergan, Inc. Laparoscopic gastric band with active agents
US8390326B2 (en) * 2009-05-05 2013-03-05 William Marsh Rice University Method for fabrication of a semiconductor element and structure thereof
US20110008271A1 (en) * 2009-07-13 2011-01-13 Jr Chem, Llc Rosacea treatments using polymetal complexes
US20110137112A1 (en) * 2009-08-28 2011-06-09 Allergan, Inc. Gastric band with electric stimulation
WO2011031400A2 (en) * 2009-08-28 2011-03-17 Allergan, Inc. Gastric band with electric stimulation
EP2484356A4 (de) * 2009-09-30 2013-12-04 Shiseido Co Ltd Oral verabreichte zusammensetzung für reduzierte faltenbildung
WO2011040185A1 (ja) * 2009-09-30 2011-04-07 株式会社資生堂 肌あれ軽減経口組成物
US9421262B2 (en) * 2009-10-28 2016-08-23 Biomed Research & Technologies, Inc. Compositions and methods for treating dermatological conditions
US8992898B2 (en) 2010-04-17 2015-03-31 Shannon Elizabeth Klingman Antiperspirants and deodorants
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
US20110171286A1 (en) * 2010-01-13 2011-07-14 Allergan, Inc. Hyaluronic acid compositions for dermatological use
US9114188B2 (en) 2010-01-13 2015-08-25 Allergan, Industrie, S.A.S. Stable hydrogel compositions including additives
US20110171311A1 (en) * 2010-01-13 2011-07-14 Allergan Industrie, Sas Stable hydrogel compositions including additives
US8758221B2 (en) * 2010-02-24 2014-06-24 Apollo Endosurgery, Inc. Source reservoir with potential energy for remotely adjustable gastric banding system
US8840541B2 (en) * 2010-02-25 2014-09-23 Apollo Endosurgery, Inc. Pressure sensing gastric banding system
JP6246468B2 (ja) 2010-03-11 2017-12-13 メルク パテント ゲーエムベーハー 治療および化粧品におけるファイバー
EP2545600A2 (de) 2010-03-11 2013-01-16 Merck Patent GmbH Strahlungsfasern
AU2010348090B2 (en) * 2010-03-12 2015-09-03 Allergan Industrie Sas A fluid composition comprising a hyaluronan polymer and mannitol for improving skin condition
ES2729994T3 (es) 2010-03-22 2019-11-07 Allergan Inc Hidrogeles reticulados de polisacárido y proteína-polisacárido para aumento de tejido blando
US9028394B2 (en) 2010-04-29 2015-05-12 Apollo Endosurgery, Inc. Self-adjusting mechanical gastric band
US20110270024A1 (en) 2010-04-29 2011-11-03 Allergan, Inc. Self-adjusting gastric band having various compliant components
US9044298B2 (en) 2010-04-29 2015-06-02 Apollo Endosurgery, Inc. Self-adjusting gastric band
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8517915B2 (en) 2010-06-10 2013-08-27 Allergan, Inc. Remotely adjustable gastric banding system
US20130226268A1 (en) 2010-07-26 2013-08-29 Merck Patent Gmbh Nanocrystals in devices
US8883139B2 (en) 2010-08-19 2014-11-11 Allergan Inc. Compositions and soft tissue replacement methods
US8697057B2 (en) 2010-08-19 2014-04-15 Allergan, Inc. Compositions and soft tissue replacement methods
US9005605B2 (en) 2010-08-19 2015-04-14 Allergan, Inc. Compositions and soft tissue replacement methods
US8889123B2 (en) 2010-08-19 2014-11-18 Allergan, Inc. Compositions and soft tissue replacement methods
WO2012027274A2 (en) 2010-08-23 2012-03-01 The Regents Of The University Of California Compositions and methods for imaging
US20120059216A1 (en) 2010-09-07 2012-03-08 Allergan, Inc. Remotely adjustable gastric banding system
US8961393B2 (en) 2010-11-15 2015-02-24 Apollo Endosurgery, Inc. Gastric band devices and drive systems
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
WO2012110178A1 (en) 2011-02-14 2012-08-23 Merck Patent Gmbh Device and method for treatment of cells and cell tissue
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
CN103702659B (zh) 2011-06-03 2016-12-21 阿勒根公司 包括抗氧化剂的皮肤填充剂组合物
EP2736331A1 (de) * 2011-07-26 2014-06-04 Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) Pflanzenschutzzusammensetzung mit alpha-hydroxysäuren
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US8876694B2 (en) 2011-12-07 2014-11-04 Apollo Endosurgery, Inc. Tube connector with a guiding tip
US8961394B2 (en) 2011-12-20 2015-02-24 Apollo Endosurgery, Inc. Self-sealing fluid joint for use with a gastric band
KR20140123555A (ko) 2012-01-30 2014-10-22 메르크 파텐트 게엠베하 파이버 상의 나노결정
WO2014011624A2 (en) 2012-07-10 2014-01-16 Xpd Holdings Llc Stabilized multi-functional antioxidant compounds and methods of use
FR2993466B1 (fr) * 2012-07-18 2014-08-15 Prevor Internat Utilisation d'une creme de protection contre les effets des agents chimiques agressifs en contact avec la peau
GB201220354D0 (en) * 2012-11-12 2012-12-26 Medpharm Ltd Dermal compositions
AU2014305758B2 (en) 2013-08-09 2017-06-15 Puretech Scientific Llc Skin care compositions having cyclic diesters and methods thereof
US10722444B2 (en) 2014-09-30 2020-07-28 Allergan Industrie, Sas Stable hydrogel compositions including additives
DE202015008361U1 (de) 2014-12-03 2016-04-21 Mary Kay Inc. Kosmetische Zusammensetzungen
WO2016128783A1 (en) 2015-02-09 2016-08-18 Allergan Industrie Sas Compositions and methods for improving skin appearance
FR3033559B1 (fr) 2015-03-13 2020-11-20 Oreal Procede de synthese de nouveaux composes derives d'acide 3-hydroxy-cyclopentyl acetique
GB201521085D0 (en) * 2015-11-30 2016-01-13 Biozep As Use
US10683576B2 (en) * 2017-03-27 2020-06-16 Baker Hughes, A Ge Company, Llc Corrosion inhibitors for passivation of galvanized coatings and carbon steel
US11433011B2 (en) 2017-05-24 2022-09-06 L'oreal Methods for treating chemically relaxed hair
JP6501937B1 (ja) * 2017-10-30 2019-04-17 株式会社 資生堂 毛髪処理剤
EP4011355A1 (de) 2017-12-29 2022-06-15 L'oreal Zusammensetzungen zur änderung der haarfärbung
EP3965724A4 (de) * 2019-05-06 2023-05-17 Spinart, LLC Formulierungen und verfahren zur herstellung von stabilen kosmetischen zusammensetzungen
KR102232072B1 (ko) 2019-05-08 2021-03-25 연세대학교 산학협력단 에틸 피루베이트를 유효성분으로 포함하는 피부 섬유증의 예방 또는 치료용 조성물
US11419809B2 (en) 2019-06-27 2022-08-23 L'oreal Hair treatment compositions and methods for treating hair
CA3167217A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods
JP2023539426A (ja) 2020-07-31 2023-09-14 パン-モントージョ,フランシスコ グリコール酸とl-アラニンの薬学的組み合わせについて
FR3118872B1 (fr) * 2021-01-15 2024-02-02 Oreal Composition multiphasique comprenant un alpha-hydroxyacide
WO2022131141A1 (en) * 2020-12-14 2022-06-23 L'oreal Multi-phase composition comprising alpha hydroxy acid
CN115869294B (zh) * 2022-10-25 2023-10-20 广东药科大学 托品酸及其衍生物在制备治疗银屑病药物中的用途
CN115650948B (zh) * 2022-11-01 2023-12-19 中国科学院长春应用化学研究所 一种乙丙交酯的制备方法

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1772075A (en) * 1928-04-16 1930-08-05 Guy S Exon Vehicle propelled turntable
US2118666A (en) * 1936-02-20 1938-05-24 Burndy Engineering Co Inc Cable connecter
US3078537A (en) * 1960-07-14 1963-02-26 Louis H Morin Invisible scoop stringers employing abrasive preventing means
US3227010A (en) * 1963-08-13 1966-01-04 Midas Internat Corp Method of and means for installation of a crankcase ventilating system
FR1439834A (fr) * 1963-12-07 1966-05-27 Utilisation nouvelle en cosmétologie d'un activateur cellulaire
US3689668A (en) * 1967-10-18 1972-09-05 Emile Leon Piette Method of alleviating wrinkles on skin
SE325667B (de) * 1968-03-06 1970-07-06 Medisan Ab
US3856934A (en) * 1970-06-24 1974-12-24 A Kligman Skin depigmentation
GB1388836A (en) * 1971-06-01 1975-03-26 Medisan Ab Cosmetic compositions
US3879537A (en) * 1973-09-04 1975-04-22 Scott Eugene J Van Treatment of ichthyosiform dermatoses
US3955470A (en) * 1973-09-13 1976-05-11 Kruzell George R Bolt operating and locking mechanism for closed breech rocket gun
US3906108A (en) * 1973-10-12 1975-09-16 Johnson & Johnson Stabilized tretinoin cream emulsion
US3984566A (en) * 1974-02-25 1976-10-05 Scott Eugene J Van Method of alleviating the symptoms of dandruff
ZA752066B (en) * 1974-05-02 1976-03-31 Draco Ab Dermatologically active preparation
US3891184A (en) * 1974-07-01 1975-06-24 Meredith Fields Multi-purpose lift device
US4105762A (en) * 1975-02-05 1978-08-08 Rohm And Haas Company Metal salt complexes of 1-substituted aralkyl imidazoles, and methods and compositions for controlling phytopathogenic fungi using them
US4105782A (en) * 1975-03-07 1978-08-08 Yu Ruey J Treatment of acne and dandruff
US4021572A (en) * 1975-07-23 1977-05-03 Scott Eugene J Van Prophylactic and therapeutic treatment of acne vulgaris utilizing lactamides and quaternary ammonium lactates
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
US4197316A (en) * 1975-07-23 1980-04-08 Scott Eugene J Van Treatment of dry skin
US4380549A (en) * 1975-07-23 1983-04-19 Scott Eugene J Van Topical treatment of dry skin
US4053630A (en) * 1976-07-07 1977-10-11 Yu Ruey J Treatment of body odor and disturbed keratinization
US4105763A (en) * 1976-10-22 1978-08-08 Hoechst Aktiengesellschaft 1-Methyl-2-(phenyl-oxymethyl)-5-nitro-imidazoles
NO782652L (no) * 1978-08-02 1980-02-05 Arne Gjerde Beskyttelsesanordning for motordrevet sirkelsag
US4234599A (en) * 1978-10-04 1980-11-18 Scott Eugene J Van Treatment of skin keratoses with α-hydroxy acids and related compounds
US4246261A (en) * 1979-08-09 1981-01-20 Scott Eugene J Van Additives enhancing topical corticosteroid action
US4287214A (en) * 1979-09-24 1981-09-01 Scott Eugene J Van Dithranol compositions stabilized with alpha hydroxyacids
US4417203A (en) * 1981-05-26 1983-11-22 International Business Machines Corporation System for contactless electrical property testing of multi-layer ceramics
JPS587A (ja) * 1981-06-25 1983-01-05 Matsushita Electric Ind Co Ltd 燃焼装置
US4603146A (en) * 1984-05-16 1986-07-29 Kligman Albert M Methods for retarding the effects of aging of the skin
AU548341B2 (en) * 1982-02-02 1985-12-05 Unilever Plc Acne treatment composition
US4518798A (en) * 1982-09-30 1985-05-21 Exxon Research & Engineering Co. Preparing esters and carboxylic acids from lower olefins
DE3540175C2 (de) * 1985-11-13 1997-03-27 Merck Patent Gmbh Dithranolhaltige pharmazeutische Zubereitung
US4929722A (en) * 1986-06-06 1990-05-29 Union Carbide Chemicals And Plastics Company Inc. Acid decrystallization of aminopolysaccharides and derivatives thereof
AU618517B2 (en) * 1986-12-23 1992-01-02 Eugene J. Van Scott Additives enhancing topical actions of therapeutic agents
US5091171B2 (en) * 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US5702688A (en) * 1986-12-23 1997-12-30 Tristrata Technology, Inc. Amphoteric compositions and polymeric forms of alpha hydroxyacids, and their therapeutic use
JPH0511368Y2 (de) * 1987-12-02 1993-03-22
US5001171A (en) * 1987-12-07 1991-03-19 Bridgestone/Firestone, Inc. Process, modified rubbers and rubber compositions
US5021451A (en) * 1988-11-14 1991-06-04 Hoffman-La Roche Inc. Method for inhibiting hyperproliferative diseases
US5033100A (en) * 1989-06-26 1991-07-16 Fuji Photo Film Co., Ltd. Method and apparatus for classifying picture elements in radiation images
US5153230A (en) * 1989-10-06 1992-10-06 Perfective Cosmetics, Inc. Topical skin cream composition
US5108761A (en) * 1990-10-01 1992-04-28 The Procter & Gamble Company Method of preventing tooth enamel erosion utilizing an acidic beverage containing calcium
TW247878B (de) * 1991-07-02 1995-05-21 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
CA2019273A1 (en) 1991-02-15
CA2337750A1 (en) 1991-02-15
CA2337750C (en) 2002-10-15
CA2019273C (en) 2001-05-29
EP0413528B1 (de) 1995-11-15
US5886042A (en) 1999-03-23
AU5913990A (en) 1991-02-21
MX9203653A (es) 1992-09-01
GR3018157T3 (en) 1996-02-29
EP0671162A3 (de) 1995-12-27
US5883128A (en) 1999-03-16
US6060512A (en) 2000-05-09
US5091171B1 (en) 1995-09-26
DK0413528T3 (da) 1996-03-11
US5886041A (en) 1999-03-23
EP0671162A2 (de) 1995-09-13
DE69023574D1 (de) 1995-12-21
AU701962B2 (en) 1999-02-11
ATE130187T1 (de) 1995-12-15
ES2081936T3 (es) 1996-03-16
EP0413528A1 (de) 1991-02-20
US5091171A (en) 1992-02-25
US5091171B2 (en) 1997-07-15
AU660917B2 (en) 1995-07-13
AU3311095A (en) 1996-02-15

Similar Documents

Publication Publication Date Title
DE69023574D1 (de) Amphotere Zusammensetzungen und Polymerformen von alpha-Hydroxy-Säuren, und ihre therapeutische Anwendung.
BR9403783A (pt) Uso de uma composição cosmética
FI911986A0 (fi) Farmaceutiska foereningar.
DE10299026I2 (de) Neue Thienylcarbonsäureester von Aminoalkoholen, ihre Quaternierungsprodukte sowie die Herstellung und Verwendung dieser Verbindungen.
ATE203019T1 (de) Neue (r)-5-carbamoyl-8-fluor-3-n,n- disubstituierte-amino-3,4-dihydro-2h-1- benzopyrane
ATE160561T1 (de) L-carnitin-salz, dieses enthaltende kosmetische und pharmazeutische zusammensetzungen zur behandlung von dermatosen
DE69917858D1 (de) Gebrauch von Silicongummi zur Stabilisierung von Ascorbinsaüre und Vorbereitungen die diese Zusammensetzungen enthalten
ATE312603T1 (de) Theanin enthaltende zusammensetzung zur unterdrückung von verhaltensstörungen der haustieren
ATE140703T1 (de) Diaminsalze von clavulansäure
ES2124861T3 (es) Derivados de aminoacidos y su utilizacion como inhibidores de la encefalinasa.
DE69503724T2 (de) L-Carnitin-Salz, dieses enthaltende kosmetische und pharmazeutische Zusammensetzungen zur Behandlung von Dermatosen
ATE95421T1 (de) Piroxicam enthaltende pharmazeutische zusammensetzung zur topischen anwendung.
ATE91689T1 (de) Geminale bisphosphonsaeuren und deren derivate als antiarthritische mittel.
DE59401990D1 (de) Imidazolyl-substituierte Phenylessigsäureprolinamide
ES2074623T3 (es) Utilizacion de aminoacidos para la proteccion de tejidos cardiacos isquemicos y su recuperacion metabolica.
DE69210727D1 (de) Verwendung von 1,2-Dipalmitoyl-L-Alpha-Phosphatidyl-N,N-Dimethylethanilamine in dermatologischen und kosmetischen Zusammensetzungen
DE382180T1 (de) Derivate von thiazolidin-4-carbonsaeure, deren herstellung und sie enthaltende pharmazeutische zusammensetzungen.
MX12192A (es) Composicion farmaceutica para reducir o impedir las arritmias
ES2191671T3 (es) Esteres de 1,4-dihidropiridina 4-fenil-3-sustituidos.
DE500713T1 (de) Derivate des 3,3,5-trimethylcyclohexylesters von 2-methylpropionsaeure, ihr herstellungsverfahren sowie diese enthaltende therapeutische kompositionen.
ATE30715T1 (de) Cyclohexancarbonsaeuren und deren derivate als mittel gegen arrhythmie.

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation