DE69020422T2 - Zusammensetzung in Form eines Schaumes enthaltend 5-Aminosalicylic Säure zur intra-rektal Verabreichung. - Google Patents

Zusammensetzung in Form eines Schaumes enthaltend 5-Aminosalicylic Säure zur intra-rektal Verabreichung.

Info

Publication number
DE69020422T2
DE69020422T2 DE69020422T DE69020422T DE69020422T2 DE 69020422 T2 DE69020422 T2 DE 69020422T2 DE 69020422 T DE69020422 T DE 69020422T DE 69020422 T DE69020422 T DE 69020422T DE 69020422 T2 DE69020422 T2 DE 69020422T2
Authority
DE
Germany
Prior art keywords
intra
rectal administration
aminosalicylic acid
composition
foam containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69020422T
Other languages
English (en)
Other versions
DE69020422D1 (de
DE69020422T3 (de
Inventor
John Norman Charles Healey
Marshall Whiteman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Original Assignee
Smith Kline and French Laboratories Ltd
GlaxoSmithKline LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10655759&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69020422(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smith Kline and French Laboratories Ltd, GlaxoSmithKline LLC filed Critical Smith Kline and French Laboratories Ltd
Publication of DE69020422D1 publication Critical patent/DE69020422D1/de
Publication of DE69020422T2 publication Critical patent/DE69020422T2/de
Application granted granted Critical
Publication of DE69020422T3 publication Critical patent/DE69020422T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
DE69020422T 1989-04-26 1990-04-23 Zusammensetzung in Form eines Schaumes enthaltend 5-Aminosalicylic Säure zur intra-rektal Verabreichung. Expired - Lifetime DE69020422T3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898909559A GB8909559D0 (en) 1989-04-26 1989-04-26 Pharmaceutical compositions

Publications (3)

Publication Number Publication Date
DE69020422D1 DE69020422D1 (de) 1995-08-03
DE69020422T2 true DE69020422T2 (de) 1995-11-16
DE69020422T3 DE69020422T3 (de) 2000-03-30

Family

ID=10655759

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69020422T Expired - Lifetime DE69020422T3 (de) 1989-04-26 1990-04-23 Zusammensetzung in Form eines Schaumes enthaltend 5-Aminosalicylic Säure zur intra-rektal Verabreichung.

Country Status (17)

Country Link
US (1) US5082651A (de)
EP (1) EP0395329B2 (de)
JP (1) JP2566662B2 (de)
KR (1) KR0179344B1 (de)
AT (1) ATE124261T1 (de)
AU (1) AU623245B2 (de)
CA (1) CA2014889C (de)
DE (1) DE69020422T3 (de)
DK (1) DK0395329T4 (de)
ES (1) ES2074124T5 (de)
GB (1) GB8909559D0 (de)
GR (2) GR3017367T3 (de)
HK (1) HK1004521A1 (de)
IE (1) IE67621B1 (de)
NZ (1) NZ233415A (de)
PT (1) PT93884B (de)
ZA (1) ZA903127B (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9000485D0 (sv) * 1990-02-09 1990-02-09 Pharmacia Ab Foamable composition for pharmaceutical use, use thereof and method of treatment
IT1243379B (it) * 1990-07-27 1994-06-10 Giuliani Spa Composizione farmaceutica adatta alla somministrazione rettale di principi attivi che esplicano un'azione di medicazione a livello del colon prevalentemente di tipo topico
JP3425441B2 (ja) * 1990-10-22 2003-07-14 ガストロ サービシイズ ピーティーワイ リミテッド 非炎症性及び非感染性腸障害の処置
IT1247529B (it) * 1991-04-24 1994-12-17 Poli Ind Chimica Spa Composizioni farmaceutiche in forma di schiuma per somministrazione intravaginale, cutanea e orale
AU1907992A (en) * 1991-06-07 1993-01-08 Byk Nederland Bv Pharmaceutical enema preparation
FR2713486B1 (fr) * 1993-12-14 1996-02-09 Scophysa Nouvelles compositions pour mousses, notamment mousses rectales, et mousses ainsi obtenues.
DE4420735C2 (de) * 1994-06-15 1996-09-05 Allphamed Arzneimittel Gmbh Verfahren zur Herstellung mechanisch stabiler, sich mit hoher Auflösegeschwindigkeit auszeichnender Brausetabletten
GB9414699D0 (en) * 1994-07-21 1994-09-07 Slagel David Aqueous foamable composition
GB9503119D0 (en) * 1995-02-17 1995-04-05 Durand Ltd Medication and apparatus and method of applying medication
US6166024A (en) 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
US6326364B1 (en) 1999-02-08 2001-12-04 Cedars-Sinai Medical Center Use of 5-aminosalicylates as antimicrobial agents
JP2001072576A (ja) * 1999-09-03 2001-03-21 Kissei Pharmaceut Co Ltd 経口用医薬品組成物
EP1214925B1 (de) * 1999-09-06 2006-06-14 Setsuko Ueda Chemisches mittel zum entfernen von hautschuppen
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
TWI249519B (en) 2000-08-29 2006-02-21 Nobex Corp Immunoregulatory compounds and derivatives and methods of treating diseases therewith
CA2359812C (en) 2000-11-20 2004-02-10 The Procter & Gamble Company Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures
US8048924B2 (en) * 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
EP1312368A1 (de) * 2001-11-19 2003-05-21 Dr. Falk Pharma Gmbh Zusammensetzungen enthaltend Mesalazin zur Behandlung von entzündlichen Darmerkrankungen
WO2004037225A2 (en) * 2002-10-25 2004-05-06 Foamix Ltd. Cosmetic and pharmaceutical foam
IL152486A0 (en) * 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US20050186142A1 (en) * 2002-10-25 2005-08-25 Foamix Ltd. Kit and composition of imidazole with enhanced bioavailability
US9211259B2 (en) * 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US10117812B2 (en) * 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20070292355A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Anti-infection augmentation foamable compositions and kit and uses thereof
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US20060193789A1 (en) * 2002-10-25 2006-08-31 Foamix Ltd. Film forming foamable composition
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US20080317679A1 (en) * 2002-10-25 2008-12-25 Foamix Ltd. Foamable compositions and kits comprising one or more of a channel agent, a cholinergic agent, a nitric oxide donor, and related agents and their uses
US20080206161A1 (en) * 2002-10-25 2008-08-28 Dov Tamarkin Quiescent foamable compositions, steroids, kits and uses thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US20050271596A1 (en) * 2002-10-25 2005-12-08 Foamix Ltd. Vasoactive kit and composition and uses thereof
US20050069566A1 (en) * 2003-08-04 2005-03-31 Foamix Ltd. Foam carrier containing amphiphilic copolymeric gelling agent
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US7704518B2 (en) * 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US20060233721A1 (en) * 2002-10-25 2006-10-19 Foamix Ltd. Foam containing unique oil globules
US20050205086A1 (en) * 2002-10-25 2005-09-22 Foamix Ltd. Retinoid immunomodulating kit and composition and uses thereof
US9668972B2 (en) * 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US20070292359A1 (en) * 2002-10-25 2007-12-20 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
US8486376B2 (en) * 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8486374B2 (en) * 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
CN1856294A (zh) * 2003-08-25 2006-11-01 弗米克斯有限公司 渗透性药物泡沫
US20100112088A1 (en) * 2003-08-29 2010-05-06 Jay Pravda Materials and methods for treatment of disorders associated with oxidative stress
US8916546B2 (en) 2003-08-29 2014-12-23 Therapeutic Research Llc Materials and methods for treatment and diagnosis of disorders associated with oxidative stress
ZA200507017B (en) * 2004-02-04 2007-03-28 Foamix Ltd Cosmetic and pharmaceutical foam with solid matter
HUE028158T2 (en) 2004-07-07 2016-12-28 Biocon Ltd Synthesis of bound immunoregulatory compounds
US20080152596A1 (en) * 2005-07-19 2008-06-26 Foamix Ltd. Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof
EP2061467A4 (de) * 2006-09-08 2013-08-21 Foamix Ltd Gefärbte oder färbbare und schäumbare zusammensetzung sowie schaumstoff dafür
US20080260655A1 (en) * 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
EP2073794A2 (de) * 2006-11-14 2009-07-01 Foamix Ltd. Stabile, nicht-alkoholische und schäumbare pharmazeutische emulsionszusammensetzungen mit einem geschmeidigen weichmacher
US7645801B2 (en) * 2007-01-29 2010-01-12 Alaven Pharmaceutical Llc Reduced irritant enema for treatment of inflammatory bowel disease (IBD)
MX2009013683A (es) * 2007-06-13 2010-04-07 Jay Pravda Materiales y metodos para el tratamiento y diagnostico de trastornos asociados con estres oxidativo.
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US20090130029A1 (en) * 2007-11-21 2009-05-21 Foamix Ltd. Glycerol ethers vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) * 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
EP2242476A2 (de) * 2008-01-14 2010-10-27 Foamix Ltd. Aufschäumbare pharmazeutische poloxamer-zusammensetzungen mit wirkstoffen und/oder therapeutischen zellen und verwendungen
CA2760186C (en) 2009-04-28 2019-10-29 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
US8945516B2 (en) 2009-10-02 2015-02-03 Foamix Pharmaceuticals Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
MX2012005883A (es) 2009-11-23 2012-10-09 Cipla Ltd Composicion topica en espuma.
CA2781579A1 (en) 2009-11-23 2011-05-26 Cipla Limited Topical foam composition
US8174881B2 (en) 2009-11-24 2012-05-08 Micron Technology, Inc. Techniques for reducing disturbance in a semiconductor device
AU2013342069B2 (en) 2012-11-09 2018-05-31 Haz Two, Llc Enema composition for treatment of ulcerative colitis having long term stability
JP2015168654A (ja) * 2014-03-07 2015-09-28 三笠製薬株式会社 ＮＳＡＩＤｓ含有泡沫化製剤用水性組成物
CA2978573A1 (en) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions and methods for treating rosacea and acne
US20190351060A1 (en) * 2016-12-16 2019-11-21 Ferring B.V. Rectal Foam Formulations

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1304682A (de) * 1969-02-03 1973-01-24
US3866800A (en) * 1969-02-12 1975-02-18 Alberto Culver Co Non-pressurized package containing self-heating products
AU1314370A (en) * 1970-02-09 1971-09-30 Alberto-Culver Company Gas-releasable and foamable compositions
US3997467A (en) * 1971-11-26 1976-12-14 Pharmacia Aktiebolag Foam forming composition
US4112942A (en) * 1974-10-09 1978-09-12 Reckitt & Colman Products Limited Method of preparing and administering a foam enema
AR205589A1 (es) * 1974-10-09 1976-05-14 Reckitt & Colmann Prod Ltd Dispositivo introductor de una composicion acuosa en una cavidad corporal
DE2755224A1 (de) * 1976-12-15 1978-07-13 Procter & Gamble Schmerzen und entzuendungen linderndes mittel zur oertlichen anwendung
US4211777A (en) * 1977-11-25 1980-07-08 Fisons Limited Compositions comprising a compound having sodium cromoglycate activity and aminosalicylic acid
WO1981002672A1 (en) * 1980-03-20 1981-10-01 Ferring Farma Lab Pharmaceutical composition and method for the treatment of colitis ulcerosa and crohn's disease
US4440763A (en) * 1981-03-18 1984-04-03 Block Drug Company, Inc. Use of 4-aminosalicyclic acid as an anti-inflammatory agent
SU1172558A1 (ru) * 1983-07-11 1985-08-15 Научно-исследовательский институт проктологии Способ лечени воспалительных заболеваний толстой кишки
US4664256A (en) * 1983-09-06 1987-05-12 Farmaceutisk Laboratorium Ferring A/S Packaged stable enema solution or suspension containing 5-aminosalicyclic acid
US4657900A (en) * 1983-09-27 1987-04-14 Rowell Laboratories Pharmaceutical article of manufacture comprising a bisulfite stabilized aqueous solution of 5-aminosalicylic acid and method
FR2561919B1 (fr) * 1984-04-03 1986-12-19 Roussel Uclaf Composition pharmaceutique constituee d'une part, a titre de principe actif, par la 9a,11b-dichloro 16a-methyl 21-oxycarbonyldicyclohexyl methyloxy pregna-1,4-diene 3,20-dione et d'autre part, par un excipient pharmaceutique inerte apte a permettre l'action du produit dans le rectum ou le colon
US4639367A (en) * 1985-03-18 1987-01-27 Product Resources International, Inc. Aerosol foam
US4752465A (en) * 1985-09-20 1988-06-21 Product Resources International, Inc. Aerosol foam
US4889709A (en) * 1985-03-18 1989-12-26 Product Resources International, Inc. Aerosol foam with adsorbate and container containing same
EP0251462A3 (de) * 1986-05-28 1988-10-26 Lloyd I. Osipow Polymer und Treibmittel enthaltende Zusammensetzungen für geschäumte Strukturen
AU1388388A (en) * 1987-04-01 1988-10-06 Dak-Laboratoriet A/S Benzoic acid derivatives and use thereof
US4945084A (en) * 1987-07-08 1990-07-31 Norman Oksman Method and composition for topically treating anorectal or other dermal wounds

Also Published As

Publication number Publication date
IE901469L (en) 1990-10-26
AU623245B2 (en) 1992-05-07
KR900015741A (ko) 1990-11-10
ATE124261T1 (de) 1995-07-15
KR0179344B1 (ko) 1999-03-20
DK0395329T4 (da) 2000-04-10
GR3032575T3 (en) 2000-05-31
HK1004521A1 (en) 1998-11-27
DE69020422D1 (de) 1995-08-03
GR3017367T3 (en) 1995-12-31
GB8909559D0 (en) 1989-06-14
EP0395329A2 (de) 1990-10-31
IE67621B1 (en) 1996-04-17
AU5367290A (en) 1990-11-01
JP2566662B2 (ja) 1996-12-25
NZ233415A (en) 1991-05-28
ES2074124T5 (es) 2000-01-16
DE69020422T3 (de) 2000-03-30
CA2014889C (en) 2000-05-30
DK0395329T3 (da) 1995-10-30
EP0395329B2 (de) 1999-11-17
CA2014889A1 (en) 1990-10-26
ES2074124T3 (es) 1995-09-01
EP0395329A3 (de) 1991-11-21
PT93884B (pt) 1996-10-31
JPH02295928A (ja) 1990-12-06
US5082651A (en) 1992-01-21
PT93884A (pt) 1990-11-20
EP0395329B1 (de) 1995-06-28
ZA903127B (en) 1991-12-24

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8363 Opposition against the patent
8366 Restricted maintained after opposition proceedings