DE69002353T2 - Inhalationsgerät. - Google Patents

Inhalationsgerät.

Info

Publication number
DE69002353T2
DE69002353T2 DE1990602353 DE69002353T DE69002353T2 DE 69002353 T2 DE69002353 T2 DE 69002353T2 DE 1990602353 DE1990602353 DE 1990602353 DE 69002353 T DE69002353 T DE 69002353T DE 69002353 T2 DE69002353 T2 DE 69002353T2
Authority
DE
Germany
Prior art keywords
inhalation
inhaler
medicine
airflow
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1990602353
Other languages
English (en)
Other versions
DE69002353D1 (de
Inventor
Jan Anders Roland Andersson
Nils Goeran Nilsson
Per-Olof Stefan Fagerstroem
Thomas Mikael Wendel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Draco AB
Original Assignee
Draco AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco AB filed Critical Draco AB
Publication of DE69002353D1 publication Critical patent/DE69002353D1/de
Application granted granted Critical
Publication of DE69002353T2 publication Critical patent/DE69002353T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/009Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • A61J7/0409Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers
    • A61J7/0418Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers with timers with electronic history memory
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/0003Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A61M2016/0018Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical
    • A61M2016/0021Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors electrical with a proportional output signal, e.g. from a thermistor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3375Acoustical, e.g. ultrasonic, measuring means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/43General characteristics of the apparatus making noise when used correctly
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/14Static flow deviators in tubes disturbing laminar flow in tubes, e.g. archimedes screws

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Electrodes Of Semiconductors (AREA)
  • Meat, Egg Or Seafood Products (AREA)
  • Respiratory Apparatuses And Protective Means (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
DE1990602353 1989-03-07 1990-03-02 Inhalationsgerät. Expired - Lifetime DE69002353T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8900793A SE466684B (sv) 1989-03-07 1989-03-07 Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator

Publications (2)

Publication Number Publication Date
DE69002353D1 DE69002353D1 (de) 1993-09-02
DE69002353T2 true DE69002353T2 (de) 1993-12-02

Family

ID=20375263

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1990602353 Expired - Lifetime DE69002353T2 (de) 1989-03-07 1990-03-02 Inhalationsgerät.

Country Status (16)

Country Link
US (1) US5331953A (de)
EP (1) EP0387222B1 (de)
JP (1) JP2927541B2 (de)
KR (1) KR0135309B1 (de)
AT (1) ATE91911T1 (de)
AU (1) AU613264B2 (de)
CA (1) CA2028830C (de)
DE (1) DE69002353T2 (de)
DK (1) DK0387222T3 (de)
ES (1) ES2042267T3 (de)
FI (1) FI102948B1 (de)
IE (1) IE64129B1 (de)
NO (1) NO175289C (de)
PT (1) PT93347B (de)
SE (1) SE466684B (de)
WO (1) WO1990010470A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017080871A3 (de) * 2015-11-13 2017-06-29 Alfred Von Schuckmann Handbetätigbarer inhalator

Families Citing this family (222)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1240750B (it) * 1990-04-12 1993-12-17 Chiesi Farma Spa Dispositivo per la somministrazione di sostanze medicamentose in polvere
DE69127826T2 (de) * 1990-12-17 1998-04-09 Minnesota Mining & Mfg Inhalationsgerät
IT1248059B (it) * 1991-06-14 1995-01-05 Miat Spa Insufflatore multidose per farmaci in polvere
ATE359842T1 (de) * 1991-07-02 2007-05-15 Nektar Therapeutics Abgabevorrichtung für nebelförmige medikamente
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
JPH0822314B2 (ja) * 1991-09-26 1996-03-06 シェリング・コーポレーション エアロゾル薬物用の吸入器
US5363842A (en) * 1991-12-20 1994-11-15 Circadian, Inc. Intelligent inhaler providing feedback to both patient and medical professional
DE9307115U1 (de) * 1992-05-29 1993-09-02 Ggu Gesundheits Umweltforsch Vorrichtung zur Erzeugung inhalierbarer Wirkstoffe
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
GB2273660B (en) * 1992-09-11 1996-07-17 Aid Medic Ltd Drug delivery arrangement
CZ287848B6 (en) * 1992-12-18 2001-02-14 Schering Corp Inhalator of powder substances
WO1994016756A1 (en) * 1993-01-29 1994-08-04 Miris Medical Corporation Intrapulmonary delivery of hormones
US5505195A (en) * 1993-09-16 1996-04-09 Medtrac Technologies Inc. Dry powder inhalant device with dosage and air flow monitor
US5505192A (en) * 1993-11-12 1996-04-09 New-Med Corporation Dispenser monitoring system
DE4422710C1 (de) * 1994-06-29 1995-09-14 Boehringer Ingelheim Kg Inhalationsgerät mit einem Elektronikmodul zur Funktionsüberwachung
US6390088B1 (en) 1993-12-13 2002-05-21 Boehringer Ingelheim Kg Aerosol inhaler
DE4400084C2 (de) * 1994-01-04 2001-08-02 Softec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester in einem Luftstrom fein verteilter Form
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
MX9603936A (es) 1994-03-07 1997-05-31 Inhale Therapeutic Syst Metodos y composiciones para el suministro pulmonar de insulina.
US5839429A (en) * 1994-03-25 1998-11-24 Astra Aktiebolag Method and apparatus in connection with an inhaler
AU124387S (en) * 1994-03-25 1995-08-11 Astra Ab Training device for an inhaler
SE9401020D0 (sv) * 1994-03-25 1994-03-25 Astra Ab Method and apparatus in connection with an inhaler
WO1996009085A1 (en) 1994-09-21 1996-03-28 Inhale Therapeutic Systems Apparatus and methods for dispersing dry powder medicaments
JP3853360B2 (ja) * 1994-10-24 2006-12-06 パウダージェクト リサーチ リミテッド 粒子供給装置
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
US5507278A (en) * 1994-11-18 1996-04-16 Karell; Manuel L. Tongue-guard for inhaler
US5495848A (en) * 1994-11-25 1996-03-05 Nellcar Puritan Bennett Monitoring system for delivery of therapeutic gas
SE9404140D0 (sv) * 1994-11-29 1994-11-29 Astra Ab Dose indicating device
US5544647A (en) * 1994-11-29 1996-08-13 Iep Group, Inc. Metered dose inhalator
US5622163A (en) * 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
DE19500764C2 (de) * 1995-01-13 2001-09-27 Sofotec Gmbh & Co Kg Vorrichtung zum Verabreichen von Medikamenten in fester, in einem Luftstrom fein verteilter Form
US5758637A (en) * 1995-08-31 1998-06-02 Aerogen, Inc. Liquid dispensing apparatus and methods
US6085740A (en) 1996-02-21 2000-07-11 Aerogen, Inc. Liquid dispensing apparatus and methods
US5780014A (en) * 1995-04-14 1998-07-14 Inhale Therapeutic Systems Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin
SE9502800D0 (sv) * 1995-08-10 1995-08-10 Astra Ab Disposable inhaler
JP3317823B2 (ja) * 1995-08-11 2002-08-26 株式会社ユニシアジェックス 投薬器
US5649554A (en) * 1995-10-16 1997-07-22 Philip Morris Incorporated Electrical lighter with a rotatable tobacco supply
US5724986A (en) * 1995-11-06 1998-03-10 Jones Medical Instrument Co. Casing and spirometer for metered dose inhaler
DK0865302T3 (da) 1995-12-07 2000-10-02 Jago Pharma Ag Inhalator til gentagen dosisvis afgivelse af farmakologisk tørpulver
US7131441B1 (en) 1995-12-07 2006-11-07 Skyepharma Ag Inhaler for multiple dosed administration of a pharmacological dry powder
JP3830972B2 (ja) * 1996-02-21 2006-10-11 シェーリング コーポレイション 粉体薬剤吸入器
US5890490A (en) * 1996-11-29 1999-04-06 Aylsworth; Alonzo C. Therapeutic gas flow monitoring system
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
GB9700226D0 (en) * 1997-01-08 1997-02-26 Glaxo Group Ltd Inhalation device
SE9700940D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler IV
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
SE9700948D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler X
SE9700938D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
US6006747A (en) * 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5911219A (en) * 1997-04-18 1999-06-15 Aylsworth; Alonzo C. Therapeutic gas flow meter and monitor
TW533865U (en) 1997-06-10 2003-05-21 Glaxo Group Ltd Dispenser for dispensing medicament and actuation indicating device
CA2212430A1 (en) * 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
IT238038Y1 (it) * 1997-11-12 2000-09-29 Miat Spa Erogatore multidose di una sostanza in polvere o in grani,del tipo incui l'approntamento di una dose comporta la rotazione di un alberino
US6142339A (en) 1998-01-16 2000-11-07 1263152 Ontario Inc. Aerosol dispensing device
CA2315777C (en) 1998-01-16 2008-12-23 1263152 Ontario Inc. Indicating device for use with a dispensing device
US6358058B1 (en) 1998-01-30 2002-03-19 1263152 Ontario Inc. Aerosol dispensing inhaler training device
JP3488620B2 (ja) * 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
AU138849S (en) * 1998-03-30 1999-11-22 Astra Ab Inhaler with cap
US6729330B2 (en) 1998-05-05 2004-05-04 Trudell Medical International Indicating device for aerosol container
US6082358A (en) 1998-05-05 2000-07-04 1263152 Ontario Inc. Indicating device for aerosol container
US6336453B1 (en) 1999-04-30 2002-01-08 Trudell Medical International Indicating device for aerosol container
US6257233B1 (en) 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
US6142146A (en) * 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device
AU2003231650B2 (en) * 1998-06-12 2004-12-02 Microdose Therapeutx, Inc. Metering, packaging and delivery of pharmaceuticals and drugs
US6152130A (en) * 1998-06-12 2000-11-28 Microdose Technologies, Inc. Inhalation device with acoustic control
CA2334590C (en) * 1998-06-12 2009-08-18 Microdose Technologies, Inc. Inhalation device
US6260549B1 (en) 1998-06-18 2001-07-17 Clavius Devices, Inc. Breath-activated metered-dose inhaler
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
AU5970899A (en) 1998-08-28 2000-03-21 Glaxo Group Limited Dispenser
US6223744B1 (en) 1999-03-16 2001-05-01 Multi-Vet Ltd. Wearable aerosol delivery apparatus
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6235177B1 (en) 1999-09-09 2001-05-22 Aerogen, Inc. Method for the construction of an aperture plate for dispensing liquid droplets
US7971588B2 (en) 2000-05-05 2011-07-05 Novartis Ag Methods and systems for operating an aerosol generator
US7575761B2 (en) 2000-06-30 2009-08-18 Novartis Pharma Ag Spray drying process control of drying kinetics
US6546927B2 (en) 2001-03-13 2003-04-15 Aerogen, Inc. Methods and apparatus for controlling piezoelectric vibration
US6745760B2 (en) 2001-05-15 2004-06-08 Trudell Medical International Medicament applicator
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
JP4795637B2 (ja) 2001-09-28 2011-10-19 カーブ テクノロジー,インコーポレイティド 鼻ネブライザー
WO2003057291A1 (en) 2002-01-07 2003-07-17 Aerogen, Inc. Devices and methods for nebulizing fluids for inhalation
US7677467B2 (en) 2002-01-07 2010-03-16 Novartis Pharma Ag Methods and devices for aerosolizing medicament
WO2003059424A1 (en) 2002-01-15 2003-07-24 Aerogen, Inc. Methods and systems for operating an aerosol generator
ES2300568T3 (es) 2002-03-20 2008-06-16 Mannkind Corporation Aparato de inhalacion.
US7004164B2 (en) 2002-03-21 2006-02-28 Trudell Medical International Indicating device for aerosol container
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
US7582284B2 (en) * 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US6830046B2 (en) 2002-04-29 2004-12-14 Hewlett-Packard Development Company, L.P. Metered dose inhaler
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US8122881B2 (en) * 2002-05-09 2012-02-28 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US20030221687A1 (en) * 2002-05-09 2003-12-04 William Kaigler Medication and compliance management system and method
US6915962B2 (en) 2002-05-20 2005-07-12 Aerogen, Inc. Apparatus for providing aerosol for medical treatment and methods
DK1539286T3 (en) 2002-09-16 2015-04-27 Sanofi Sa INHALATOR FOR POWDER-DEFINED NAME MEDICAL SUBSTANCES
US6886557B2 (en) * 2002-10-31 2005-05-03 Hewlett-Packard Development Company, L.P. Inhalation device and method for delivering variable amounts of different components
US7275534B2 (en) * 2003-01-31 2007-10-02 Hewlett-Packard Development Company, L.P. Medicament ejector with ejection port servicing
US7726303B2 (en) * 2003-02-25 2010-06-01 Hewlett-Packard Development Company, L.P. Controlled medicament ejection
US8616195B2 (en) 2003-07-18 2013-12-31 Novartis Ag Nebuliser for the production of aerosolized medication
GB2398065A (en) * 2003-10-16 2004-08-11 Bespak Plc Dispensing apparatus
US7621273B2 (en) 2003-10-28 2009-11-24 Trudell Medical International Indicating device with warning dosage indicator
US7100530B2 (en) 2003-12-15 2006-09-05 Trudell Medical International, Inc. Dose indicating device
US7481213B2 (en) * 2004-02-11 2009-01-27 Hewlett-Packard Development Company, L.P. Medicament dispenser
US7467630B2 (en) * 2004-02-11 2008-12-23 Hewlett-Packard Development Company, L.P. Medicament dispenser
US7946291B2 (en) 2004-04-20 2011-05-24 Novartis Ag Ventilation systems and methods employing aerosol generators
JP4682554B2 (ja) * 2004-07-30 2011-05-11 横浜ゴム株式会社 シーリング材組成物
MX2007001903A (es) 2004-08-20 2007-08-02 Mannkind Corp Catalisis de sintesis de dicetopiperazina.
KR101306384B1 (ko) 2004-08-23 2013-09-09 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는디케토디옥산염
US7543582B2 (en) 2004-09-20 2009-06-09 Trudell Medical International Dose indicating device with display elements attached to container
ATE452671T1 (de) 2004-10-21 2010-01-15 Novo Nordisk As Injektionsvorrichtung mit einem prozessor zur sammlung von ausstossinformationen
WO2006045523A1 (en) 2004-10-21 2006-05-04 Novo Nordisk A/S Medication delivery system with a detector for providing a signal indicative of an amount of an ejected dose of drug
JP5189369B2 (ja) 2005-01-20 2013-04-24 トルーデル メディカル インターナショナル 分与装置
AU2006231741A1 (en) * 2005-03-30 2006-10-12 Canon Kabushiki Kaisha Liquid medicine ejection device
EP2392258B1 (de) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-Informatiksystem
US8836513B2 (en) 2006-04-28 2014-09-16 Proteus Digital Health, Inc. Communication system incorporated in an ingestible product
US8912908B2 (en) 2005-04-28 2014-12-16 Proteus Digital Health, Inc. Communication system with remote activation
US8802183B2 (en) 2005-04-28 2014-08-12 Proteus Digital Health, Inc. Communication system with enhanced partial power source and method of manufacturing same
CA2807044C (en) 2005-05-03 2014-06-10 The University Of Western Ontario An oral device and kit for use in association therewith
EA012656B1 (ru) 2005-05-25 2009-12-30 Аэроджен, Инк. Вибрационные системы и их применение
JP5465878B2 (ja) 2005-09-14 2014-04-09 マンカインド コーポレイション 活性薬剤に対する結晶性微粒子表面の親和性を増大させることに基づく薬物処方の方法
CN104383546B (zh) 2006-02-22 2021-03-02 曼金德公司 用于改善包含二酮哌嗪和活性剂的微粒的药物性质的方法
KR100638340B1 (ko) * 2006-03-15 2006-10-27 송인호 낙곡 회수용 흡입기
JP5183620B2 (ja) 2006-03-20 2013-04-17 ノボ・ノルデイスク・エー/エス 機械的薬剤投与デバイス用の電子モジュール
JP5241714B2 (ja) 2006-07-07 2013-07-17 プロテウス デジタル ヘルス, インコーポレイテッド スマートな非経口送達システム
US8141550B2 (en) 2006-08-01 2012-03-27 Trudell Medical International Dispensing device
US20080058772A1 (en) * 2006-08-31 2008-03-06 Robertson Timothy L Personal paramedic
KR20090129998A (ko) 2007-02-11 2009-12-17 맵 파마슈티컬스, 인코포레이티드 부작용 프로파일을 최소화하면서 편두통의 빠른 완화를 가능하게 하는 dhe의 치료적 투여 방법
US7907477B2 (en) * 2007-03-02 2011-03-15 Scott Puzia Bottle cap medication timer
US9270025B2 (en) 2007-03-09 2016-02-23 Proteus Digital Health, Inc. In-body device having deployable antenna
US8261738B2 (en) * 2007-07-24 2012-09-11 Respironics Respiratory Drug Delivery (Uk) Ltd. Apparatus and method for maintaining consistency for aerosol drug delivery treatments
US9125979B2 (en) 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
EP2058025B1 (de) * 2007-11-09 2014-09-03 Hitachi Ltd. Vorrichtung zur Verabreichung von Pulvermedikation
WO2009067463A1 (en) 2007-11-19 2009-05-28 Proteus Biomedical, Inc. Body-associated fluid transport structure evaluation devices
EP2230934B8 (de) 2007-12-14 2012-10-24 AeroDesigns, Inc Abgabe von aerosol-sprühbaren nahrungsmittelprodukten
US10004657B2 (en) 2008-02-08 2018-06-26 The University Of Western Ontario Method of brain activation
JP5570497B2 (ja) 2008-04-15 2014-08-13 トルーデル メディカル インターナショナル 嚥下エアーパルス治療マウスピース及びその使用方法
US8082873B2 (en) 2008-05-05 2011-12-27 Trudell Medical International Drive mechanism for an indicating device
US8087548B2 (en) * 2008-05-14 2012-01-03 S.C. Johnson & Son, Inc. Spray products with particles and improved valve for inverted dispensing without clogging
US8181591B1 (en) 2008-05-23 2012-05-22 Trudell Medical International Domed actuator for indicating device
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN104689432B (zh) 2008-06-13 2018-07-06 曼金德公司 干粉吸入器和用于药物输送的系统
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
WO2010008523A1 (en) 2008-07-13 2010-01-21 Map Pharmaceuticals, Inc. Methods and apparatus for delivering aerosolized medication
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
KR101214453B1 (ko) 2008-08-13 2012-12-24 프로테우스 디지털 헬스, 인코포레이티드 복용 가능한 회로
BRPI0912918B8 (pt) * 2008-08-25 2021-06-22 Koninklijke Philips Electronics Nv aparelho de aplicação de fármaco respiratório, e método de encorajar o uso de um aparelho respiratório de liberação de drogas
EP2626098B1 (de) 2008-10-22 2020-08-19 Trudell Medical International Modulares Aerosolabgabesystem
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
PL2405963T3 (pl) 2009-03-11 2014-04-30 Mannkind Corp Urządzenie, układ i sposób pomiaru oporu inhalatora
WO2010111403A2 (en) 2009-03-25 2010-09-30 Proteus Biomedical, Inc. Probablistic pharmacokinetic and pharmacodynamic modeling
CN102458236B (zh) 2009-04-28 2016-01-27 普罗秋斯数字健康公司 高可靠性的可摄入事件标记器及其使用方法
EP2440184B1 (de) 2009-06-12 2023-04-05 MannKind Corporation Diketopiperazin-mikropartikel mit definierten spefiischen oberflächenbereichen
WO2011056889A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
WO2011083377A1 (en) * 2010-01-07 2011-07-14 Koninklijke Philips Electronics N.V. Respiratory drug delivery apparatus including a feedback and compliance device
CN102905612A (zh) 2010-02-01 2013-01-30 普罗秋斯数字健康公司 双腕式数据采集系统
JP5841951B2 (ja) 2010-02-01 2016-01-13 プロテウス デジタル ヘルス, インコーポレイテッド データ収集システム
US20110282248A1 (en) 2010-03-04 2011-11-17 Martin Ruth E Portable high frequency air pulse delivery device
WO2011127252A2 (en) 2010-04-07 2011-10-13 Proteus Biomedical, Inc. Miniature ingestible device
EP2557986A4 (de) * 2010-04-11 2014-01-22 Proteus Digital Health Inc Vorrichtung, system und verfahren zur erkennung und verabreichung einer medizinischen dosis
GB201006901D0 (en) 2010-04-26 2010-06-09 Sagentia Ltd Device for monitoring status and use of an inhalation or nasal drug delivery device
RU2571331C1 (ru) 2010-06-21 2015-12-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
JP2014504902A (ja) 2010-11-22 2014-02-27 プロテウス デジタル ヘルス, インコーポレイテッド 医薬品を有する摂取可能なデバイス
RU2591625C2 (ru) 2011-03-15 2016-07-20 Новартис Аг Ингалятор
WO2012127046A2 (en) * 2011-03-24 2012-09-27 Sanofi-Aventis Deutschland Gmbh Device and method for detecting an actuation action performable with a medical device
DK2694402T3 (en) 2011-04-01 2017-07-03 Mannkind Corp BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US9756874B2 (en) 2011-07-11 2017-09-12 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2015112603A1 (en) 2014-01-21 2015-07-30 Proteus Digital Health, Inc. Masticable ingestible product and communication system therefor
WO2013016784A1 (en) * 2011-08-04 2013-02-07 Victor Esteve Dry powder inhaler
WO2013036881A2 (en) * 2011-09-07 2013-03-14 Syphase, Llc Dry powder inhalation device
AU2012328885B2 (en) 2011-10-24 2017-08-31 Mannkind Corporation Methods and compositions for treating pain
US9767708B2 (en) 2012-04-04 2017-09-19 Genia Medical Inc. Medicament training device and system
US10283014B2 (en) 2012-04-04 2019-05-07 Jbcb Holdings, Llc Smart packaging and display system
CA3176610A1 (en) 2012-06-25 2014-01-03 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and patient interaction
AU2013289957B2 (en) 2012-07-12 2017-02-23 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014018454A1 (en) 2012-07-23 2014-01-30 Proteus Digital Health, Inc. Techniques for manufacturing ingestible event markers comprising an ingestible component
US10029056B2 (en) 2012-08-29 2018-07-24 The Provost, Fellows, Foundation Scholars, & The Other Members Of Board, Of The College Of The Holy & Undivided Trinity Of Queen Elizabeth Near Dublin System and method for monitoring use of a device
JP5869736B2 (ja) 2012-10-18 2016-02-24 プロテウス デジタル ヘルス, インコーポレイテッド 通信デバイス用の電源において電力消失およびブロードキャスト電力を適応的に最適化するための装置、システム、および方法
GB2507104A (en) 2012-10-19 2014-04-23 Nicoventures Holdings Ltd Electronic inhalation device
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
TWI659994B (zh) 2013-01-29 2019-05-21 美商普羅托斯數位健康公司 高度可膨脹之聚合型薄膜及包含彼之組成物
JP5941240B2 (ja) 2013-03-15 2016-06-29 プロテウス デジタル ヘルス, インコーポレイテッド 金属検出器装置、システム、および方法
JP6469025B2 (ja) 2013-03-15 2019-02-13 トゥルーデル メディカル インターナショナル 口腔マウスピース及びその使用方法
EP3587404B1 (de) 2013-03-15 2022-07-13 MannKind Corporation Mikrokristalline diketopiperazinzusammensetzungen, verfahren zur herstellung und deren verwendung
US8807131B1 (en) 2013-06-18 2014-08-19 Isonea Limited Compliance monitoring for asthma inhalers
JP2016526471A (ja) * 2013-07-12 2016-09-05 オシラリ リミテッド ライアビリティ カンパニー 音声に基づく薬物送達モニター
BR112016000937A8 (pt) 2013-07-18 2021-06-22 Mannkind Corp formulações farmacêuticas de pó seco, método para a fabricação de uma formulação de pó seco e uso de uma formulação farmacêutica de pó seco
JP2016530930A (ja) 2013-08-05 2016-10-06 マンカインド コーポレイション 通気装置及び方法
CA2922686C (en) 2013-08-28 2023-03-07 Gecko Health Innovations, Inc. Devices, systems, and methods for adherence monitoring and devices, systems, and methods for monitoring use of consumable dispensers
ES2834636T3 (es) * 2013-08-30 2021-06-18 Adherium Nz Ltd Un monitor de cumplimiento para un inhalador de medicamento
US9796576B2 (en) 2013-08-30 2017-10-24 Proteus Digital Health, Inc. Container with electronically controlled interlock
US10019555B2 (en) 2013-10-19 2018-07-10 Cohero Health, Inc. Interactive respiratory device usage tracking system
US11424017B2 (en) 2013-10-19 2022-08-23 Aptargroup, Inc. Respiratory system and method that monitors medication flow
US10084880B2 (en) 2013-11-04 2018-09-25 Proteus Digital Health, Inc. Social media networking based on physiologic information
DK3113817T3 (da) * 2014-03-03 2021-02-01 Adherium Nz Ltd Overvågningsmonitor til en indretning til administration af medikamenter på tør pulverform
EP3122406B1 (de) * 2014-03-25 2017-11-22 Koninklijke Philips N.V. Inhalator mit zwei mikrofonen zum nachweis des inhalationsflusses
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
SE538400C2 (sv) * 2014-04-03 2016-06-14 Iconovo Ab Torrpulverinhalator
SE538399C2 (sv) * 2014-04-03 2016-06-14 Iconovo Ab Torrpulverinhalator
SE539930C2 (sv) * 2014-04-03 2018-01-23 Iconovo Ab Torrpulverinhalator
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
KR20160098719A (ko) * 2015-02-11 2016-08-19 엘지전자 주식회사 약통을 위한 디지털 캡 및 모바일 디바이스의 제어 방법
EP3058970A1 (de) 2015-02-19 2016-08-24 Sanofi-Aventis Deutschland GmbH Datensammlungsvorrichtung zur Befestigung an einer Injektionsvorrichtung
EP4316552A3 (de) 2015-06-09 2024-04-17 Sanofi-Aventis Deutschland GmbH Datensammelvorrichtung zur befestigung an einer injektionsvorrichtung
US11051543B2 (en) 2015-07-21 2021-07-06 Otsuka Pharmaceutical Co. Ltd. Alginate on adhesive bilayer laminate film
GB201517089D0 (en) 2015-09-28 2015-11-11 Nicoventures Holdings Ltd Vaping heat map system and method for electronic vapour provision systems
CN109152891B (zh) 2016-03-24 2022-11-08 特鲁德尔医学国际公司 具有电子指示器的呼吸护理系统
BR112018070608B1 (pt) 2016-04-12 2022-05-03 Biocorp Production S.A Dispositivo complementar de observância do inalador dosimetrado e inalador dosimetrado
US10512921B2 (en) * 2016-05-09 2019-12-24 Funai Electric Co., Ltd. Maintenance apparatus for vaporizing device
CA3225148A1 (en) 2016-05-19 2017-11-23 Mannkind Corporation Apparatus, system and method for detecting and monitoring inhalations
MX2018014121A (es) 2016-05-19 2019-04-29 Trudell Medical Int Camara de retencion con valvula inteligente.
CA3028604C (en) 2016-07-08 2023-12-05 Trudell Medical International Smart oscillating positive expiratory pressure device
KR20210018961A (ko) 2016-07-22 2021-02-18 프로테우스 디지털 헬스, 인코포레이티드 섭취 가능한 이벤트 마커의 전자기 감지 및 검출
IL265827B2 (en) 2016-10-26 2023-03-01 Proteus Digital Health Inc Methods for producing capsules with ingestible event markers
CA3036631A1 (en) 2016-12-09 2018-06-14 Trudell Medical International Smart nebulizer
US10989803B1 (en) 2017-08-21 2021-04-27 Massachusetts Institute Of Technology Security protocol for motion tracking systems
US11666801B2 (en) 2018-01-04 2023-06-06 Trudell Medical International Smart oscillating positive expiratory pressure device
EP3772252B1 (de) * 2018-03-26 2022-05-04 Philip Morris Products S.A. Inhalator mit einem durchlöcherten porösen trägerelement
US11071836B2 (en) 2018-03-29 2021-07-27 Reciprocal Labs Corporation Single dose inhaler monitoring attachment
WO2019215471A1 (en) 2018-05-11 2019-11-14 Biocorp Production S.A. Handheld metered dose inhaler
US11395890B2 (en) 2018-06-04 2022-07-26 Trudell Medical International Smart valved holding chamber
CA3152072A1 (en) 2019-08-27 2021-03-04 Trudell Medical International Smart oscillating positive expiratory pressure device

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
IT941426B (it) * 1971-07-17 1973-03-01 Isf Spa Inalatore a camera di turbinio per sostanze medicamentose polveriformi
US4109656A (en) * 1977-02-07 1978-08-29 Sybron Corporation Apparatus for use with insufflators
IL58720A (en) * 1979-01-11 1984-02-29 Scherico Ltd Inhalation device
GB2063075B (en) * 1979-11-07 1983-11-09 Sterwin Ag Dose indicator for inhalers
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
NZ209900A (en) * 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4811731A (en) * 1985-07-30 1989-03-14 Glaxo Group Limited Devices for administering medicaments to patients
CA1258054A (en) * 1986-04-25 1989-08-01 Robert E. Newell Indicating device
US4830022A (en) * 1987-07-27 1989-05-16 Medical Engineering And Development, Inc. Animal monitoring system
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
US5020527A (en) * 1990-02-20 1991-06-04 Texax-Glynn Corporation Inhaler device with counter/timer means
US5042467A (en) * 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017080871A3 (de) * 2015-11-13 2017-06-29 Alfred Von Schuckmann Handbetätigbarer inhalator
US10722664B2 (en) 2015-11-13 2020-07-28 Alfred Von Schuckmann Manually actuatable inhaler

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NO175289B (no) 1994-06-20
AU613264B2 (en) 1991-07-25
ATE91911T1 (de) 1993-08-15
FI102948B (fi) 1999-03-31
KR920700050A (ko) 1992-02-19
DE69002353D1 (de) 1993-09-02
NO904809L (no) 1990-11-05
ES2042267T3 (es) 1993-12-01
US5331953A (en) 1994-07-26
SE8900793D0 (sv) 1989-03-07
IE64129B1 (en) 1995-07-12
CA2028830A1 (en) 1990-09-08
SE8900793L (sv) 1990-09-08
CA2028830C (en) 2000-02-08
IE900765L (en) 1990-09-07
PT93347B (pt) 1998-05-29
DK0387222T3 (da) 1993-08-30
WO1990010470A1 (en) 1990-09-20
EP0387222A1 (de) 1990-09-12
NO175289C (no) 1994-09-28
NO904809D0 (no) 1990-11-05
SE466684B (sv) 1992-03-23
PT93347A (pt) 1990-11-07
AU5271090A (en) 1990-10-09
FI102948B1 (fi) 1999-03-31
EP0387222B1 (de) 1993-07-28
KR0135309B1 (ko) 1998-04-23
FI905521A0 (fi) 1990-11-07
JP2927541B2 (ja) 1999-07-28

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