DE68922614T2 - Antisense-oligonukleotide gegen c-myb proto-oncogene und deren verwendungen. - Google Patents

Antisense-oligonukleotide gegen c-myb proto-oncogene und deren verwendungen.

Info

Publication number
DE68922614T2
DE68922614T2 DE68922614T DE68922614T DE68922614T2 DE 68922614 T2 DE68922614 T2 DE 68922614T2 DE 68922614 T DE68922614 T DE 68922614T DE 68922614 T DE68922614 T DE 68922614T DE 68922614 T2 DE68922614 T2 DE 68922614T2
Authority
DE
Germany
Prior art keywords
oncogenes
oligonucleotides
antisense
myb
myb proto
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68922614T
Other languages
English (en)
Other versions
DE68922614D1 (de
Inventor
Alan Gewirtz
Bruno Calabretta
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Temple University of Commonwealth System of Higher Education
Original Assignee
Temple University of Commonwealth System of Higher Education
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Temple University of Commonwealth System of Higher Education filed Critical Temple University of Commonwealth System of Higher Education
Application granted granted Critical
Publication of DE68922614D1 publication Critical patent/DE68922614D1/de
Publication of DE68922614T2 publication Critical patent/DE68922614T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
DE68922614T 1988-11-07 1989-11-03 Antisense-oligonukleotide gegen c-myb proto-oncogene und deren verwendungen. Expired - Fee Related DE68922614T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26790188A 1988-11-07 1988-11-07
US40802689A 1989-09-15 1989-09-15
US07/427,659 US5098890A (en) 1988-11-07 1989-10-27 Antisence oligonucleotides to c-myb proto-oncogene and uses thereof
PCT/US1989/004927 WO1990005445A1 (en) 1988-11-07 1989-11-03 Antisense oligonucleotides to c-myb proto-oncogene and uses thereof

Publications (2)

Publication Number Publication Date
DE68922614D1 DE68922614D1 (de) 1995-06-14
DE68922614T2 true DE68922614T2 (de) 1996-01-11

Family

ID=27402019

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68922614T Expired - Fee Related DE68922614T2 (de) 1988-11-07 1989-11-03 Antisense-oligonukleotide gegen c-myb proto-oncogene und deren verwendungen.

Country Status (7)

Country Link
US (1) US5098890A (de)
EP (1) EP0424476B1 (de)
AT (1) ATE122234T1 (de)
AU (1) AU641636B2 (de)
DE (1) DE68922614T2 (de)
DK (1) DK3591D0 (de)
WO (1) WO1990005445A1 (de)

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Also Published As

Publication number Publication date
AU5035090A (en) 1990-06-12
ATE122234T1 (de) 1995-05-15
DK3591D0 (da) 1991-01-09
DE68922614D1 (de) 1995-06-14
EP0424476B1 (de) 1995-05-10
AU641636B2 (en) 1993-09-30
EP0424476A4 (en) 1992-05-06
EP0424476A1 (de) 1991-05-02
WO1990005445A1 (en) 1990-05-31
US5098890A (en) 1992-03-24

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