DE68915329T2 - Adsorbens,das eine Beschichtung von Polyethylenimin derivatisiert mit hydrophoben Gruppen beinhaltet ; seine Herstellung und Anwendung für Immuntests und Separationen. - Google Patents

Adsorbens,das eine Beschichtung von Polyethylenimin derivatisiert mit hydrophoben Gruppen beinhaltet ; seine Herstellung und Anwendung für Immuntests und Separationen.

Info

Publication number
DE68915329T2
DE68915329T2 DE68915329T DE68915329T DE68915329T2 DE 68915329 T2 DE68915329 T2 DE 68915329T2 DE 68915329 T DE68915329 T DE 68915329T DE 68915329 T DE68915329 T DE 68915329T DE 68915329 T2 DE68915329 T2 DE 68915329T2
Authority
DE
Germany
Prior art keywords
immunoassays
separations
adsorbent
manufacture
coating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68915329T
Other languages
English (en)
Other versions
DE68915329D1 (de
Inventor
Philip Hon-Peng Lau
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dade Behring Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Application granted granted Critical
Publication of DE68915329D1 publication Critical patent/DE68915329D1/de
Publication of DE68915329T2 publication Critical patent/DE68915329T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545—Synthetic resin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/824—Immunological separation techniques
DE68915329T 1988-05-02 1989-04-27 Adsorbens,das eine Beschichtung von Polyethylenimin derivatisiert mit hydrophoben Gruppen beinhaltet ; seine Herstellung und Anwendung für Immuntests und Separationen. Expired - Fee Related DE68915329T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/188,956 US4952519A (en) 1988-05-02 1988-05-02 Protein immobilization with poly(ethyleneimine) derivatized with a hydroprobic group

Publications (2)

Publication Number Publication Date
DE68915329D1 DE68915329D1 (de) 1994-06-23
DE68915329T2 true DE68915329T2 (de) 1994-09-22

Family

ID=22695269

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68915329T Expired - Fee Related DE68915329T2 (de) 1988-05-02 1989-04-27 Adsorbens,das eine Beschichtung von Polyethylenimin derivatisiert mit hydrophoben Gruppen beinhaltet ; seine Herstellung und Anwendung für Immuntests und Separationen.

Country Status (4)

Country Link
US (1) US4952519A (de)
EP (1) EP0341498B1 (de)
JP (1) JPH0734859B2 (de)
DE (1) DE68915329T2 (de)

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US6274324B1 (en) * 1989-12-01 2001-08-14 Unilever Patent Holdings B.V. Specific binding reagent comprising a variable domain protein linked to a support or tracer
GB8927230D0 (en) * 1989-12-01 1990-01-31 Unilever Plc Reagents
DE4015157A1 (de) * 1990-05-11 1991-11-14 Miles Inc Asymetrische sandwich-membranen fuer diagnose-teststreifen
SE467308B (sv) * 1990-10-22 1992-06-29 Berol Nobel Ab Fast yta belagd med ett hydrofilt ytterskikt med kovalent bundna biopolymerer, saett att framstaella en saadan yta och ett konjugat daerfoer
SE467309B (sv) * 1990-10-22 1992-06-29 Berol Nobel Ab Hydrofiliserad fast yta, foerfarande foer dess framstaellning samt medel daerfoer
JP2994739B2 (ja) * 1990-11-29 1999-12-27 和光純薬工業株式会社 微量成分の迅速測定方法
GB9026903D0 (en) * 1990-12-11 1991-01-30 Couture Leonard Table grill
US5314830A (en) * 1992-10-30 1994-05-24 University Of New Mexico Immobilized hydrophobically-modified antibodies
DE4341524C2 (de) * 1993-12-06 1997-01-16 Gluesenkamp Karl Heinz Dr Verfahren zur Immobilisierung von Biomolekülen und Affinitätsliganden an polymere Träger
US5527711A (en) * 1993-12-13 1996-06-18 Hewlett Packard Company Method and reagents for binding chemical analytes to a substrate surface, and related analytical devices and diagnostic techniques
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
CA2473376A1 (en) 2002-01-16 2003-07-31 Dynal Biotech Asa Method for isolating nucleic acids and protein from a single sample
US7141369B2 (en) * 2002-04-25 2006-11-28 Semibio Technology, Inc. Measuring cellular metabolism of immobilized cells
GB0229287D0 (en) * 2002-12-16 2003-01-22 Dna Res Innovations Ltd Polyfunctional reagents
EP1746424A4 (de) * 2004-05-14 2008-05-14 Tohoku Techno Arch Co Ltd Verfahren zur immobilisierung von protein, proteinchip, verfahren zur immobilisierung einer zelle und zellchip
WO2011153464A2 (en) * 2010-06-03 2011-12-08 New York University In situ oriented immobilization of proteins on a support

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US3619371A (en) * 1967-07-03 1971-11-09 Nat Res Dev Production of a polymeric matrix having a biologically active substance bound thereto
US3796634A (en) * 1970-03-19 1974-03-12 Us Health Education & Welfare Insolubilized biologically active enzymes
GB1380898A (en) * 1970-12-11 1975-01-15 Koch Light Lab Ltd Bonding of enzymes enzyme derivatives and other biologically active compounds to polymeric materials and polymeric materials to which such biologically active compounds can be bound
US4006059A (en) * 1974-07-29 1977-02-01 Purdue Research Foundation Hydrophobic noncovalent binding of proteins to support materials
US4001583A (en) * 1974-10-04 1977-01-04 Barrett M James Covalently bound biological substances to plastic materials and use in radioassay
CS181417B1 (en) * 1975-03-27 1978-03-31 Miroslav Bleha Method for preparing insoluble biologically active compounds
CA1083508A (fr) * 1975-11-13 1980-08-12 Jacques Grange Supports porteurs de chaines laterales, procedes d'obtention de ces supports, procedes de fixation de composes organiques comportant un residu glucidique sur lesdits supports, produits et reactifs resultant de ladite fixation chimique
DE2603319C3 (de) * 1976-01-29 1979-08-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur Fixierung von biologisch aktiven Proteinen an Trägern
US4045384A (en) * 1976-07-23 1977-08-30 The Dow Chemical Company Method for forming an amide bond between a latex and protein
US4176006A (en) * 1978-01-13 1979-11-27 Redpath Sugars Limited Enzyme immobilization with a disulphide bridge
US4278651A (en) * 1978-09-27 1981-07-14 Becton Dickinson & Company Supported receptor and use thereof in an assay
US4220565A (en) * 1979-01-18 1980-09-02 Scripps Clinic & Research Foundation Immunochemical conjugates: method and composition
US4245005A (en) * 1979-02-28 1981-01-13 Purdue Research Foundation Pellicular coated support and method
US4279787A (en) * 1979-07-30 1981-07-21 Tetra Consultants Inc. Method of binding antigens to insoluble polymeric substances
US4286964A (en) * 1979-10-12 1981-09-01 Seed Brian S Polyfunctional epoxides and halohydrins used as bridging groups to bind aromatic amine group-containing alcohols and thiols to hydroxyl bearing substrates
US4253995A (en) * 1980-02-11 1981-03-03 Scripps Clinic And Research Foundation Immunochemical conjugates: method and composition
US4253996A (en) * 1980-02-13 1981-03-03 Scripps Clinic And Research Foundation Immunochemical conjugates: method and composition
JPS56115727A (en) * 1980-02-19 1981-09-11 Kuraray Co Ltd Carrier for immobilizing physiologically active substance
JPS56141559A (en) * 1980-04-04 1981-11-05 Toray Ind Inc Reagent for immunological inspection
US4444879A (en) * 1981-01-29 1984-04-24 Science Research Center, Inc. Immunoassay with article having support film and immunological counterpart of analyte
WO1983002954A1 (en) * 1982-02-23 1983-09-01 Ventrex Lab Inc Multipurpose supports for immunological and biological use
DE3223885A1 (de) * 1982-06-26 1983-12-29 Basf Ag, 6700 Ludwigshafen Makroporoese, hydrophile traeger fuer enzyme
JPS5980442A (ja) * 1982-09-24 1984-05-09 ベクトン・デイツキンソン・アンド・カンパニ− 大分子結合用の化学的変成表面
JPS5968344A (ja) * 1982-10-12 1984-04-18 Agency Of Ind Science & Technol 非対称機能膜及びその製法
DE3311889A1 (de) * 1983-03-31 1984-10-11 Byk-Mallinckrodt Chemische Produkte Gmbh, 6057 Dietzenbach Verfahren zur irreversiblen bindung von protein an polystyroloberflaechen unter erhaltung der biologischen aktivitaet, so erhaltene polystyroloberflaechen und ihre verwendung
EP0134307B1 (de) * 1983-07-29 1989-04-19 Henning Berlin GmbH Chemie und Pharmawerk Voraktivierte Kunststoffoberflächen zur Immobilisierung von organisch-chemischen und biologischen Materialien, Verfahren zur Herstellung und Verwendung derselben
US4582810A (en) * 1983-09-30 1986-04-15 Becton, Dickinson And Company Immuno-agglutination particle suspensions
US4609707A (en) * 1983-11-10 1986-09-02 Genetic Systems Corporation Synthesis of polymers containing integral antibodies
DE3408299A1 (de) * 1984-03-07 1985-09-12 Bayer Ag, 5090 Leverkusen Verfahren zur immobilisierung von zellen und enzymen
US4615985A (en) * 1984-04-16 1986-10-07 Genetic Diagnostics Corporation Immobilized protein on nylon for immunoassay
US4806546A (en) * 1985-09-30 1989-02-21 Miles Inc. Immobilization of nucleic acids on derivatized nylon supports
US4753983A (en) * 1986-05-07 1988-06-28 Bioprobe International, Inc. Polymeric matrix for affinity chromatography and immobilization of ligands
US4808530A (en) * 1986-09-05 1989-02-28 The Ohio State University Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface

Also Published As

Publication number Publication date
US4952519A (en) 1990-08-28
DE68915329D1 (de) 1994-06-23
EP0341498B1 (de) 1994-05-18
JPH0734859B2 (ja) 1995-04-19
JPH0243947A (ja) 1990-02-14
EP0341498A1 (de) 1989-11-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DADE CHEMISTRY SYSTEMS INC. (N.D.GES.D. STAATES DE

8327 Change in the person/name/address of the patent owner

Owner name: DADE BEHRING, INC.(N.D.GES.DES STAATES DELAWARE),

8339 Ceased/non-payment of the annual fee