DE68905516T2 - Hemmungsmittel des zellwachstums der glatten muskeln. - Google Patents
Hemmungsmittel des zellwachstums der glatten muskeln.Info
- Publication number
- DE68905516T2 DE68905516T2 DE8989304369T DE68905516T DE68905516T2 DE 68905516 T2 DE68905516 T2 DE 68905516T2 DE 8989304369 T DE8989304369 T DE 8989304369T DE 68905516 T DE68905516 T DE 68905516T DE 68905516 T2 DE68905516 T2 DE 68905516T2
- Authority
- DE
- Germany
- Prior art keywords
- inhibitors
- cell growth
- smooth muscles
- muscles
- smooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/189,622 US4945086A (en) | 1988-05-03 | 1988-05-03 | Smooth muscle cell growth inhibitor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68905516D1 DE68905516D1 (de) | 1993-04-29 |
DE68905516T2 true DE68905516T2 (de) | 1993-08-12 |
Family
ID=22698106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989304369T Expired - Fee Related DE68905516T2 (de) | 1988-05-03 | 1989-04-28 | Hemmungsmittel des zellwachstums der glatten muskeln. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4945086A (de) |
EP (1) | EP0341006B1 (de) |
JP (1) | JPH0284402A (de) |
DE (1) | DE68905516T2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177020A (en) * | 1985-03-28 | 1993-01-05 | Hoechst Aktiengesellschaft | Method for the immunological determination of heparan sulfate-proteoglycan and process for the preparation and purification of heparan sulfate-proteoglycan suitable for this purpose from tissues containing basal membrane |
US5486599A (en) * | 1989-03-29 | 1996-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Construction and use of synthetic constructs encoding syndecan |
WO1991006303A1 (en) * | 1989-10-27 | 1991-05-16 | Case Western Reserve University | Inhibition of cell growth by keratan sulfate, chondroitin sulfate, dermatan sulfate and other glycans |
RU2139540C1 (ru) * | 1991-01-15 | 1999-10-10 | Биоти Терапис Лтд. | Способ обнаружения озлокачествления |
AU1680692A (en) * | 1991-03-29 | 1992-11-02 | Glycomed Incorporated | Modulation of tpa activity by heparin fragments |
GB9111439D0 (en) * | 1991-05-28 | 1991-07-17 | Thrombosis Res Inst | Inhibition of vascular smooth muscle cell proliferation |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
US5705178A (en) * | 1991-05-31 | 1998-01-06 | Gliatech, Inc. | Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers |
AU2561792A (en) * | 1991-09-06 | 1993-04-05 | Children's Medical Center Corporation | Cell-type specific heparan sulfate proteoglycans and their uses |
US5407955A (en) * | 1994-02-18 | 1995-04-18 | Eli Lilly And Company | Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease |
US5665591A (en) * | 1994-12-06 | 1997-09-09 | Trustees Of Boston University | Regulation of smooth muscle cell proliferation |
US6262255B1 (en) | 1995-04-05 | 2001-07-17 | Biomm, Inc. | Non-immunogenic, biocompatible macromolecular membrane compositions, and methods for making them |
US6146847A (en) * | 1996-11-01 | 2000-11-14 | Genespan Corporation | Stabilized transient gene expression |
FI974321A0 (fi) | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
PT1588716E (pt) | 1998-08-06 | 2011-05-25 | Mountain View Pharmaceuticals | Conjugados de peg-urato oxidase e sua utiliza??o |
AU6472900A (en) * | 1999-08-10 | 2001-03-13 | Seikagaku Corporation | Glycosaminoglycan derivatives and utilization thereof |
WO2001037853A2 (en) * | 1999-11-23 | 2001-05-31 | North Shore - Long Island Jewish Health System | Methods and agents for the inhibition of smooth muscle cell proliferation |
US7259152B2 (en) | 2000-06-07 | 2007-08-21 | Alfa Wasserman, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
US20080159976A1 (en) * | 2005-04-11 | 2008-07-03 | Jacob Hartman | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
JP2008535500A (ja) | 2005-04-11 | 2008-09-04 | サビエント ファーマセウティカルズ インク. | 変異型尿酸オキシダーゼおよびその利用 |
US8148123B2 (en) | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
US7811800B2 (en) | 2005-04-11 | 2010-10-12 | Savient Pharmaceuticals, Inc. | Variant form of urate oxidase and use thereof |
EP1874919B1 (de) | 2005-04-21 | 2010-06-09 | Massachusetts Institute Of Technology | Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe |
US20090081122A1 (en) * | 2005-05-23 | 2009-03-26 | Universite De Geneve | Injectable superparamagnetic nanoparticles for treatment by hyperthermia and use for forming an hyperthermic implant |
CN102743792B (zh) | 2005-06-21 | 2014-09-24 | 夏尔再生医学公司 | 用于增强血管通路的方法和组合物 |
CN101622270B (zh) | 2006-04-12 | 2014-01-01 | 萨文特医药公司 | 用阳离子表面活性剂纯化蛋白质的方法 |
SG176897A1 (en) | 2009-06-25 | 2012-01-30 | Savient Pharmaceuticals Inc | Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2281130A2 (fr) * | 1974-08-08 | 1976-03-05 | Thomas Andre | Procede d'extraction et de traitement de glycoproteines, de mucopolysaccharides et de substances qui les accompagnent |
US4446126A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Antithrombin-heparin complex and method for its production |
DE3381236D1 (de) * | 1982-11-30 | 1990-04-05 | Univ Manchester | Produktion von angiogenen faktoren. |
FR2538404B1 (de) * | 1982-12-28 | 1985-08-23 | Anic Spa | |
US4745098A (en) * | 1984-02-24 | 1988-05-17 | The Regents Of The University Of California | Compositions and method for improving wound healing |
US4760131A (en) * | 1986-04-23 | 1988-07-26 | Collagen Corporation | Wound-healing composition |
-
1988
- 1988-05-03 US US07/189,622 patent/US4945086A/en not_active Expired - Fee Related
-
1989
- 1989-04-28 DE DE8989304369T patent/DE68905516T2/de not_active Expired - Fee Related
- 1989-04-28 EP EP89304369A patent/EP0341006B1/de not_active Expired - Lifetime
- 1989-05-02 JP JP1112307A patent/JPH0284402A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0341006A2 (de) | 1989-11-08 |
US4945086A (en) | 1990-07-31 |
JPH0284402A (ja) | 1990-03-26 |
DE68905516D1 (de) | 1993-04-29 |
EP0341006A3 (en) | 1990-11-14 |
EP0341006B1 (de) | 1993-03-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |