DE68905516D1 - Hemmungsmittel des zellwachstums der glatten muskeln. - Google Patents
Hemmungsmittel des zellwachstums der glatten muskeln.Info
- Publication number
- DE68905516D1 DE68905516D1 DE8989304369T DE68905516T DE68905516D1 DE 68905516 D1 DE68905516 D1 DE 68905516D1 DE 8989304369 T DE8989304369 T DE 8989304369T DE 68905516 T DE68905516 T DE 68905516T DE 68905516 D1 DE68905516 D1 DE 68905516D1
- Authority
- DE
- Germany
- Prior art keywords
- inhibitors
- cell growth
- smooth muscles
- muscles
- smooth
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/189,622 US4945086A (en) | 1988-05-03 | 1988-05-03 | Smooth muscle cell growth inhibitor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68905516D1 true DE68905516D1 (de) | 1993-04-29 |
DE68905516T2 DE68905516T2 (de) | 1993-08-12 |
Family
ID=22698106
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989304369T Expired - Fee Related DE68905516T2 (de) | 1988-05-03 | 1989-04-28 | Hemmungsmittel des zellwachstums der glatten muskeln. |
Country Status (4)
Country | Link |
---|---|
US (1) | US4945086A (de) |
EP (1) | EP0341006B1 (de) |
JP (1) | JPH0284402A (de) |
DE (1) | DE68905516T2 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5177020A (en) * | 1985-03-28 | 1993-01-05 | Hoechst Aktiengesellschaft | Method for the immunological determination of heparan sulfate-proteoglycan and process for the preparation and purification of heparan sulfate-proteoglycan suitable for this purpose from tissues containing basal membrane |
US5486599A (en) * | 1989-03-29 | 1996-01-23 | The Board Of Trustees Of The Leland Stanford Junior University | Construction and use of synthetic constructs encoding syndecan |
EP0493533A4 (en) * | 1989-10-27 | 1992-10-28 | Case Western Reserve University | Inhibition of cell growth by keratan sulfate, chondroitin sulfate, dermatan sulfate and other glycans |
ES2116331T3 (es) * | 1991-01-15 | 1998-07-16 | Biotie Therapies Oy | Deteccion del contenido en sindecan en los materiales biologicos tales como tejidos o fluidos fisiologicos que indican transformaciones celulares malignas. |
WO1992017506A1 (en) * | 1991-03-29 | 1992-10-15 | Glycomed, Inc. | MODULATION OF tPA ACTIVITY BY HEPARIN FRAGMENTS |
GB9111439D0 (en) * | 1991-05-28 | 1991-07-17 | Thrombosis Res Inst | Inhibition of vascular smooth muscle cell proliferation |
US5705178A (en) * | 1991-05-31 | 1998-01-06 | Gliatech, Inc. | Methods and compositions based on inhibition of cell invasion and fibrosis by anionic polymers |
US5605938A (en) * | 1991-05-31 | 1997-02-25 | Gliatech, Inc. | Methods and compositions for inhibition of cell invasion and fibrosis using dextran sulfate |
WO1993005167A1 (en) * | 1991-09-06 | 1993-03-18 | Children's Medical Center Corporation | Cell-type specific heparan sulfate proteoglycans and their uses |
US5407955A (en) * | 1994-02-18 | 1995-04-18 | Eli Lilly And Company | Methods for lowering serum cholesterol and inhibiting smooth muscle cell proliferation, restenosis, endometriosis, and uterine fibroid disease |
US5665591A (en) * | 1994-12-06 | 1997-09-09 | Trustees Of Boston University | Regulation of smooth muscle cell proliferation |
US6262255B1 (en) | 1995-04-05 | 2001-07-17 | Biomm, Inc. | Non-immunogenic, biocompatible macromolecular membrane compositions, and methods for making them |
US6146847A (en) * | 1996-11-01 | 2000-11-14 | Genespan Corporation | Stabilized transient gene expression |
FI974321A0 (fi) | 1997-11-25 | 1997-11-25 | Jenny Ja Antti Wihurin Rahasto | Multipel heparinglykosaminoglykan och en proteoglykan innehaollande dessa |
DK2158923T3 (da) | 1998-08-06 | 2013-03-25 | Mountain View Pharmaceuticals | Peg-uratoxidase-konjugater og anvendelse deraf |
WO2001012675A1 (fr) * | 1999-08-10 | 2001-02-22 | Seikagaku Corporation | Derives de glycosaminoglycane et leur utilisation |
WO2001037853A2 (en) * | 1999-11-23 | 2001-05-31 | North Shore - Long Island Jewish Health System | Methods and agents for the inhibition of smooth muscle cell proliferation |
US7259152B2 (en) | 2000-06-07 | 2007-08-21 | Alfa Wasserman, Inc. | Methods and compositions using sulodexide for the treatment of diabetic nephropathy |
CZ2007700A3 (cs) | 2005-04-11 | 2008-02-27 | Savient Pharmaceuticals, Inc. | Variantní forma urátoxidázy a její použití |
US8188224B2 (en) | 2005-04-11 | 2012-05-29 | Savient Pharmaceuticals, Inc. | Variant forms of urate oxidase and use thereof |
US20080159976A1 (en) * | 2005-04-11 | 2008-07-03 | Jacob Hartman | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
US8148123B2 (en) | 2005-04-11 | 2012-04-03 | Savient Pharmaceuticals, Inc. | Methods for lowering elevated uric acid levels using intravenous injections of PEG-uricase |
ATE470701T1 (de) | 2005-04-21 | 2010-06-15 | Massachusetts Inst Technology | Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene,einschliesslich genidentischer und nicht- genidentischer zellen, gewebe oder organe |
JP2008545665A (ja) * | 2005-05-23 | 2008-12-18 | ユニベルシテ ドゥ ジュネーブ | 高体温による処置のための注入可能な超常磁性ナノ粒子および高体温インプラントを形成するための使用 |
CN102743792B (zh) | 2005-06-21 | 2014-09-24 | 夏尔再生医学公司 | 用于增强血管通路的方法和组合物 |
KR101288027B1 (ko) | 2006-04-12 | 2013-07-22 | 새비언트 파마수티컬즈 인크. | 양이온 계면활성제를 이용한 단백질 정제 방법 |
CN102803954A (zh) | 2009-06-25 | 2012-11-28 | 萨文特制药公司 | 通过监测peg化尿酸酶治疗期间的血清尿酸预测输液反应风险和抗体介导的响应丧失的方法和试剂盒 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2281130A2 (fr) * | 1974-08-08 | 1976-03-05 | Thomas Andre | Procede d'extraction et de traitement de glycoproteines, de mucopolysaccharides et de substances qui les accompagnent |
US4446126A (en) * | 1980-09-30 | 1984-05-01 | Cutter Laboratories, Inc. | Antithrombin-heparin complex and method for its production |
GB2131294B (en) * | 1982-11-30 | 1987-06-10 | Univ Manchester | Low molecular weight angiogenic factor |
FR2538404B1 (de) * | 1982-12-28 | 1985-08-23 | Anic Spa | |
US4745098A (en) * | 1984-02-24 | 1988-05-17 | The Regents Of The University Of California | Compositions and method for improving wound healing |
US4760131A (en) * | 1986-04-23 | 1988-07-26 | Collagen Corporation | Wound-healing composition |
-
1988
- 1988-05-03 US US07/189,622 patent/US4945086A/en not_active Expired - Fee Related
-
1989
- 1989-04-28 DE DE8989304369T patent/DE68905516T2/de not_active Expired - Fee Related
- 1989-04-28 EP EP89304369A patent/EP0341006B1/de not_active Expired - Lifetime
- 1989-05-02 JP JP1112307A patent/JPH0284402A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0341006B1 (de) | 1993-03-24 |
JPH0284402A (ja) | 1990-03-26 |
EP0341006A3 (en) | 1990-11-14 |
DE68905516T2 (de) | 1993-08-12 |
US4945086A (en) | 1990-07-31 |
EP0341006A2 (de) | 1989-11-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |